B-cell translocation gene 2 positively regulates GLP-1-stimulated insulin secretion via induction of PDX-1 in pancreatic β-cells

Experimental and Molecular Medicine

Volumn 45, Issue 5, 2013, Pages

  Hwang, Seung Lark ^a   Kwon, Okyun ^a   Kim, Sun Gyun ^b   Lee, In Kyu ^c   Kim, Yong Deuk ^a  

^a Yeungnam University   (South Korea)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c Kyungpook National University School of Medicine   (South Korea)

Author keywords

B cell translocation gene 2; Glucagon like peptide 1; Insulin; Pancreatic duodenal homeobox 1

Indexed keywords

EXENDIN 4; GLUCAGON LIKE PEPTIDE 1; MESSENGER RNA; NEUROGENIC DIFFERENTIATION FACTOR; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR MAFA; TRANSCRIPTION FACTOR PDX 1; BTG2 PROTEIN, MOUSE; BTG2 PROTEIN, RAT; HOMEODOMAIN PROTEIN; IMMEDIATE EARLY PROTEIN; INSULIN; PANCREATIC AND DUODENAL HOMEOBOX 1 PROTEIN; PEPTIDE; TRANSACTIVATOR PROTEIN; TUMOR SUPPRESSOR PROTEIN; VENOM;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; B CELL TRANSLOCATION GENE 2; CONTROLLED STUDY; GENE; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE OVEREXPRESSION; IN VITRO STUDY; IN VIVO STUDY; INSULIN RELEASE; INSULIN RESISTANCE; MALE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREATIC DUODENAL HOMEOBOX 1 GENE; PROMOTER REGION; PROTEIN DNA INTERACTION; RAT; TRANSCRIPTION REGULATION; UPREGULATION; ANIMAL; C57BL MOUSE; DRUG EFFECT; GENETICS; HUMAN; METABOLISM; PROTEIN BINDING; SECRETION (PROCESS);

ADENOVIRIDAE;

ANIMALS; GENE EXPRESSION REGULATION; GLUCAGON-LIKE PEPTIDE 1; HOMEODOMAIN PROTEINS; HUMANS; IMMEDIATE-EARLY PROTEINS; INSULIN; INSULIN-SECRETING CELLS; MALE; MICE; MICE, INBRED C57BL; PEPTIDES; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RATS; TRANS-ACTIVATORS; TUMOR SUPPRESSOR PROTEINS; VENOMS;

EID: 84881125893     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.2013.47     Document Type: Article

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