Exendin-4 inhibits glucolipotoxic ER stress in pancreatic β cells via regulation of SREBP1c and C/EBPβ transcription factors

Journal of Endocrinology

Volumn 216, Issue 3, 2013, Pages 343-352

  Oh, Yoon Sin ^a,d   Lee, Youn Jung ^a   Kang, Yup ^b   Han, Jaeseok ^c   Lim, Oh Kyung ^d   Jun, Hee Sook ^a  

^a Gachon University College of Medicine   (South Korea)

^b Ajou University School of Medicine   (South Korea)

^c UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^d Gachon University Gil Hospital   (South Korea)

Author keywords

C EBP ; ER stress; Exendin 4; SREBP1c

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; CASPASE 3; CCAAT ENHANCER BINDING PROTEIN BETA; EXENDIN 4; GLUCOSE; INITIATION FACTOR 2ALPHA; PALMITIC ACID; PROTEIN IRE1; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; STRESS ACTIVATED PROTEIN KINASE;

APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; CASPASE 3; CCAAT-ENHANCER-BINDING PROTEIN-BETA; ENDOPLASMIC RETICULUM STRESS; INSULIN-SECRETING CELLS; PEPTIDES; RATS; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; VENOMS;

EID: 84875069480     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1530/JOE-12-0311     Document Type: Article

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