-
1
-
-
0033762832
-
A role for activin A and betacellulin in human fetal pancreatic cell differentiation and growth
-
Demeterco C, Beattie GM, Atala Dib S, Lopez AD, Hayek A 2000 A role for activin A and betacellulin in human fetal pancreatic cell differentiation and growth. J Clin Endocrinol Metab 85:3892-3897
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 3892-3897
-
-
Demeterco, C.1
Beattie, G.M.2
Atala Dib, S.3
Lopez, A.D.4
Hayek, A.5
-
2
-
-
0028284507
-
Hepatocyte growth factor/scatter factor has insulinotropic activity in human fetal pancreatic cells
-
Otonkoski T, Beattie GM, Rubin JS, Lopez AD, Baird A, Hayek A 1994 Hepatocyte growth factor/scatter factor has insulinotropic activity in human fetal pancreatic cells. Diabetes 43:947-953
-
(1994)
Diabetes
, vol.43
, pp. 947-953
-
-
Otonkoski, T.1
Beattie, G.M.2
Rubin, J.S.3
Lopez, A.D.4
Baird, A.5
Hayek, A.6
-
3
-
-
0027265403
-
Nicotinamide is a potent inducer of endocrine differentiation in cultured human fetal pancreatic cells
-
Otonkoski T, Beattie GM, Mally MI, Ricordi C, Hayek A 1993 Nicotinamide is a potent inducer of endocrine differentiation in cultured human fetal pancreatic cells. J Clin Invest 92:1459-1466
-
(1993)
J Clin Invest
, vol.92
, pp. 1459-1466
-
-
Otonkoski, T.1
Beattie, G.M.2
Mally, M.I.3
Ricordi, C.4
Hayek, A.5
-
4
-
-
0030953998
-
Phosphatidylinositol 3-kinase is a negative regulator of cellular differentiation
-
Ptasznik A, Beattie GM, Mally MI, Cirulli V, Lopez A, Hayek A 1997 Phosphatidylinositol 3-kinase is a negative regulator of cellular differentiation. J Cell Biol 137:1127-1136
-
(1997)
J Cell Biol
, vol.137
, pp. 1127-1136
-
-
Ptasznik, A.1
Beattie, G.M.2
Mally, M.I.3
Cirulli, V.4
Lopez, A.5
Hayek, A.6
-
5
-
-
0033513455
-
Exendin-4 stimulates both β-cell replication and neogenesis, resulting in increased β-cell mass and improved glucose tolerance in diabetic rats
-
Xu G, Stoffers DA, Habener JF, Bonner-Weir S 1999 Exendin-4 stimulates both β-cell replication and neogenesis, resulting in increased β-cell mass and improved glucose tolerance in diabetic rats. Diabetes 48:2270-2276
-
(1999)
Diabetes
, vol.48
, pp. 2270-2276
-
-
Xu, G.1
Stoffers, D.A.2
Habener, J.F.3
Bonner-Weir, S.4
-
6
-
-
0028829481
-
Constitution of a biphasic insulin response to glucose in human fetal pancreatic β-cells with glucagon-like peptide 1
-
Otonkoski T, Hayek A 1995 Constitution of a biphasic insulin response to glucose in human fetal pancreatic β-cells with glucagon-like peptide 1. J Clin Endocrinol Metab 80:3779-3783
-
(1995)
J Clin Endocrinol Metab
, vol.80
, pp. 3779-3783
-
-
Otonkoski, T.1
Hayek, A.2
-
7
-
-
0034032317
-
Insulmotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas
-
Stoffers DA, Kieffers TJ, Hussain MA, Drucker DJ, Bonner-Weir S, Habener JF, Egan JM 2000 Insulmotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas. Diabetes 49:741-748
-
(2000)
Diabetes
, vol.49
, pp. 741-748
-
-
Stoffers, D.A.1
Kieffers, T.J.2
Hussain, M.A.3
Drucker, D.J.4
Bonner-Weir, S.5
Habener, J.F.6
Egan, J.M.7
-
8
-
-
0028179423
-
Acid B galactosidase: A developmentally regulated marker of endocrine cell precursors in the human fetal pancreas
-
Beattie GM, Levine F, Mally MI, Otonkoski T, O'Brien JS, Salomon DR, Hayek A 1994 Acid B galactosidase: A developmentally regulated marker of endocrine cell precursors in the human fetal pancreas. J Clin Endocrinol Metab 78:1232-1240
-
(1994)
J Clin Endocrinol Metab
, vol.78
, pp. 1232-1240
-
-
Beattie, G.M.1
Levine, F.2
Mally, M.I.3
Otonkoski, T.4
O'Brien, J.S.5
Salomon, D.R.6
Hayek, A.7
-
9
-
-
0027733820
-
Maturation and function of human fetal pancreatic cells after cryopreservation
-
Beattie GM, Otonkoski T, Lopez AD, Hayek A 1993 Maturation and function of human fetal pancreatic cells after cryopreservation. Transplantation 56:1340-1343
-
(1993)
Transplantation
, vol.56
, pp. 1340-1343
-
-
Beattie, G.M.1
Otonkoski, T.2
Lopez, A.D.3
Hayek, A.4
-
10
-
-
0014978068
-
An improved fluorometric assay for DNA
-
Hinegardener RT 1971 An improved fluorometric assay for DNA. Anal Biochem 39:197-201
-
(1971)
Anal Biochem
, vol.39
, pp. 197-201
-
-
Hinegardener, R.T.1
-
11
-
-
0030754650
-
Experimental transplantation of human fetal and adult pancreatic islets
-
Hayek A, Beattie GM 1997 Experimental transplantation of human fetal and adult pancreatic islets. J Clin Endocrinol Metab 82:2471-2475
-
(1997)
J Clin Endocrinol Metab
, vol.82
, pp. 2471-2475
-
-
Hayek, A.1
Beattie, G.M.2
-
12
-
-
0032908654
-
Glucose-lowering and insulin-sensitizing actions of exendin 4: Studies on obese diabetic (ob/ob, db/db) mice, diabetic fatty Zucker rats, and diabetic rhesus monkeys (Macaca mulatta)
-
Young AA, Guedulin BR, Bhavsar S, Bodkin N, Jodka C, Hansen B, Denaro M 1999 Glucose-lowering and insulin-sensitizing actions of exendin 4: Studies on obese diabetic (ob/ob, db/db) mice, diabetic fatty Zucker rats, and diabetic rhesus monkeys (Macaca mulatta). Diabetes 48:1026-1034
-
(1999)
Diabetes
, vol.48
, pp. 1026-1034
-
-
Young, A.A.1
Guedulin, B.R.2
Bhavsar, S.3
Bodkin, N.4
Jodka, C.5
Hansen, B.6
Denaro, M.7
-
13
-
-
0026648961
-
Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom: Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas
-
Eng J, Kleinman WA, Singh G, Raufman JP 1992 Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom: Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas. J Biol Chem 267:7402-7405
-
(1992)
J Biol Chem
, vol.267
, pp. 7402-7405
-
-
Eng, J.1
Kleinman, W.A.2
Singh, G.3
Raufman, J.P.4
-
14
-
-
0027184119
-
Exendin-4 is a potent agonist and truncated exendin (9-39)-amide an antagonist at the GLP-1 (7-36)-amide receptor of insulin-secreting β-cells
-
Goke R, Fehman H-C, Linn T, Schmidt H, Krause M, Eng J, Goke B 1993 Exendin-4 is a potent agonist and truncated exendin (9-39)-amide an antagonist at the GLP-1 (7-36)-amide receptor of insulin-secreting β-cells. J Biol Chem 268:19650-19655
-
(1993)
J Biol Chem
, vol.268
, pp. 19650-19655
-
-
Goke, R.1
Fehman, H.-C.2
Linn, T.3
Schmidt, H.4
Krause, M.5
Eng, J.6
Goke, B.7
-
15
-
-
0034456212
-
Exendin-4 decelerates food intake, weight gain, and fat deposition in Zucker rats
-
Szayna M, Doyle ME, Betkey JA, Halloway HW, Spencer RGS, Greig HN, Egan JM 2000 Exendin-4 decelerates food intake, weight gain, and fat deposition in Zucker rats. Endocrinology 141:1936-1941
-
(2000)
Endocrinology
, vol.141
, pp. 1936-1941
-
-
Szayna, M.1
Doyle, M.E.2
Betkey, J.A.3
Halloway, H.W.4
Spencer, R.G.S.5
Greig, H.N.6
Egan, J.M.7
-
16
-
-
0032932825
-
Once daily injection of exendin-4 to diabetic mice achieves long-term beneficial effects on blood glucose concentrations
-
Greig NH, Halloway HW, De Ore KA, Jani D, Wang Y, Zhou J, Garant MJ, Egan JM 1999 Once daily injection of exendin-4 to diabetic mice achieves long-term beneficial effects on blood glucose concentrations. Diabetologia 42:45-50
-
(1999)
Diabetologia
, vol.42
, pp. 45-50
-
-
Greig, N.H.1
Halloway, H.W.2
De Ore, K.A.3
Jani, D.4
Wang, Y.5
Zhou, J.6
Garant, M.J.7
Egan, J.M.8
-
17
-
-
0034522773
-
Glucagon-like peptide-1 induces cell proliferation and pancreatic-duodenum homeobox-1 expression and increases endocrine cell mass in the pancreas of old, glucose-intolerant rats
-
Perfetti R, Zhou J, Doyle ME, Egan J 2000 Glucagon-like peptide-1 induces cell proliferation and pancreatic-duodenum homeobox-1 expression and increases endocrine cell mass in the pancreas of old, glucose-intolerant rats. Endocrinology 141:4600-4605
-
(2000)
Endocrinology
, vol.141
, pp. 4600-4605
-
-
Perfetti, R.1
Zhou, J.2
Doyle, M.E.3
Egan, J.4
-
18
-
-
0344357096
-
Glucagon-like peptide 1 stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line
-
Drucker DJ, Philippe J, Mojsov S, Chick WL, Habener JF 1987 Glucagon-like peptide 1 stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line. Proc Natl Acad Sci USA 84:3434-3438
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 3434-3438
-
-
Drucker, D.J.1
Philippe, J.2
Mojsov, S.3
Chick, W.L.4
Habener, J.F.5
-
19
-
-
0032768616
-
Glucagon-like peptide 1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA binding activity in B (1NS-1) cells
-
Buteau J, Roduit R, Susini S, Prentki M 1999 Glucagon-like peptide 1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA binding activity in B (1NS-1) cells. Diabetologia 42:856-864
-
(1999)
Diabetologia
, vol.42
, pp. 856-864
-
-
Buteau, J.1
Roduit, R.2
Susini, S.3
Prentki, M.4
-
20
-
-
0028149890
-
Insulin-promoter-factor 1 is required for pancreas development in mice
-
Jonsson J, Carlsson L, Edlund T, Edlund H 1994 Insulin-promoter-factor 1 is required for pancreas development in mice. Nature 371:606-609
-
(1994)
Nature
, vol.371
, pp. 606-609
-
-
Jonsson, J.1
Carlsson, L.2
Edlund, T.3
Edlund, H.4
-
21
-
-
0031031571
-
Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF-1 gene coding sequence
-
Stoffers DA, Zinkin NT, Stanojevic V, Clarke WL, Habener JF 1997 Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF-1 gene coding sequence. Nat Genet 15:106-110
-
(1997)
Nat Genet
, vol.15
, pp. 106-110
-
-
Stoffers, D.A.1
Zinkin, N.T.2
Stanojevic, V.3
Clarke, W.L.4
Habener, J.F.5
-
22
-
-
0027154077
-
Glucose modulates the binding of an islet-specific factor to a conserved sequence within the rat I and the human insulin promoters
-
Melloul D, Ben-Neriah Y, Cerasi E 1993 Glucose modulates the binding of an islet-specific factor to a conserved sequence within the rat I and the human insulin promoters. Proc Natl Acad Sci USA 90:3865-3869
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 3865-3869
-
-
Melloul, D.1
Ben-Neriah, Y.2
Cerasi, E.3
-
23
-
-
0030447883
-
Purification of the β-cell glucose sensitive factor that transactivates the insulin gene differentially in normal and transformed islet cells
-
Marshak S, Totary H, Cerasi E, Melloul D 1996 Purification of the β-cell glucose sensitive factor that transactivates the insulin gene differentially in normal and transformed islet cells. Proc Natl Acad Sci USA 93:15057-15062
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 15057-15062
-
-
Marshak, S.1
Totary, H.2
Cerasi, E.3
Melloul, D.4
-
25
-
-
0033009460
-
The homeodomain protein IDX-1 increases after an early burst of proliferation during pancreatic regeneration
-
Sharma A, Zangen DH, Reitz P, Taneja M, Lissauer ME, Miller CP, Weir GC, Bonner-Weir S 1999 The homeodomain protein IDX-1 increases after an early burst of proliferation during pancreatic regeneration. Diabetes 48:507-513
-
(1999)
Diabetes
, vol.48
, pp. 507-513
-
-
Sharma, A.1
Zangen, D.H.2
Reitz, P.3
Taneja, M.4
Lissauer, M.E.5
Miller, C.P.6
Weir, G.C.7
Bonner-Weir, S.8
-
26
-
-
0033385631
-
PDX-1 and Msx-2 expression in the regenerating and developing pancreas
-
Kritzik MR, Jones E, Chen Z, Krakowski M, Krahl T, Good A, Wright C, Fox H, Sarvetnick N 1999 PDX-1 and Msx-2 expression in the regenerating and developing pancreas. J Endocrinol 161:523-530
-
(1999)
J Endocrinol
, vol.161
, pp. 523-530
-
-
Kritzik, M.R.1
Jones, E.2
Chen, Z.3
Krakowski, M.4
Krahl, T.5
Good, A.6
Wright, C.7
Fox, H.8
Sarvetnick, N.9
-
27
-
-
0034463097
-
PDX-1 and cell-cell contact act in synergy to promote delta-cell development in a human pancreatic endocrine precursor cell line
-
Itkin-Ansari P, Demeterco C, Bossie S, de la Tour DD, Beattie GM, Movassat J, Mally MI, Hayek A, Levine F 2000 PDX-1 and cell-cell contact act in synergy to promote delta-cell development in a human pancreatic endocrine precursor cell line. Mol Endocrinol 14:814-822
-
(2000)
Mol Endocrinol
, vol.14
, pp. 814-822
-
-
Itkin-Ansari, P.1
Demeterco, C.2
Bossie, S.3
De la Tour, D.D.4
Beattie, G.M.5
Movassat, J.6
Mally, M.I.7
Hayek, A.8
Levine, F.9
-
28
-
-
0031775277
-
Rat endocrine pancreatic development in relation to two homeobox gene products (Pdx-1 and Nkx 6.1)
-
Oster A, Jensen J, Serup P, Galante P, Madsen OD, Larsson LI 1998 Rat endocrine pancreatic development in relation to two homeobox gene products (Pdx-1 and Nkx 6.1). J Histochem Cytochem 46:707-715
-
(1998)
J Histochem Cytochem
, vol.46
, pp. 707-715
-
-
Oster, A.1
Jensen, J.2
Serup, P.3
Galante, P.4
Madsen, O.D.5
Larsson, L.I.6
-
29
-
-
0031843386
-
Mice lacking homeodomain transcription factor Nkx 2.2 have diabetes due to arrested differentiation of pancreatic β cells
-
Sussel K, Kalamars J, Hartigan-O'Connor DJ, Meneses JJ, Pedersen RA, Rubenstein JL, German MS 1998 Mice lacking homeodomain transcription factor Nkx 2.2 have diabetes due to arrested differentiation of pancreatic β cells. Development 125:2221-2231
-
(1998)
Development
, vol.125
, pp. 2221-2231
-
-
Sussel, K.1
Kalamars, J.2
Hartigan-O'Connor, D.J.3
Meneses, J.J.4
Pedersen, R.A.5
Rubenstein, J.L.6
German, M.S.7
-
30
-
-
0035405821
-
Glucagon-like peptide 1 and exendin 4 stimulate B cell neogenesis in streptozotocin-treated newborn rats resulting in persistently improved glucose homeostasis at adult age
-
Tourrel C, Bailbé D, Meile MJ, Kergoat M, Portha B 2001 Glucagon-like peptide 1 and exendin 4 stimulate B cell neogenesis in streptozotocin-treated newborn rats resulting in persistently improved glucose homeostasis at adult age. Diabetes 50:1562-1570
-
(2001)
Diabetes
, vol.50
, pp. 1562-1570
-
-
Tourrel, C.1
Bailbé, D.2
Meile, M.J.3
Kergoat, M.4
Portha, B.5
-
31
-
-
0030969443
-
Functional β cell mass after transplantation of human fetal pancreatic cells. Differentiation or proliferation?
-
Beattie GM, Otonkoski T, Lopez AD, Hayek A 1997 Functional β cell mass after transplantation of human fetal pancreatic cells. Differentiation or proliferation? Diabetes 46:244-248
-
(1997)
Diabetes
, vol.46
, pp. 244-248
-
-
Beattie, G.M.1
Otonkoski, T.2
Lopez, A.D.3
Hayek, A.4
-
32
-
-
0031936954
-
Glucagon-like peptide 1
-
Drucker DJ 1998 Glucagon-like peptide 1. Diabetes 47:159-169
-
(1998)
Diabetes
, vol.47
, pp. 159-169
-
-
Drucker, D.J.1
|