Ontogeny of regeneration of β-cells in the neonatal rat after treatment with streptozotocin

Endocrinology

Volumn 147, Issue 5, 2006, Pages 2346-2356

  Thyssen, Sandra ^a   Arany, Edith ^a   Hill, D J ^a,b  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b LAWSON HEALTH RESEARCH INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BUFFER; GLUCAGON; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 1 [9-39]; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; GLUCOSE; GLUCOSE TRANSPORTER 2; HOMEODOMAIN PROTEIN; INSULIN; MESSENGER RNA; PROGLUCAGON; RECEPTOR BLOCKING AGENT; STREPTOZOCIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL LOSS; CELL MATURATION; CELL PROLIFERATION; CELL REGENERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; GLUCAGON BLOOD LEVEL; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; HOMEOBOX; HORMONE SYNTHESIS; HYPERGLYCEMIA; MOUSE; NEWBORN PERIOD; NONHUMAN; ONTOGENY; PANCREAS; PANCREAS ISLET; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL HYPERPLASIA; PERINATAL PERIOD; PHENOTYPE; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; RNA ANALYSIS; TARGET CELL; TISSUE LEVEL;

ANIMALS; ANIMALS, NEWBORN; CELL PROLIFERATION; DNA PRIMERS; FEMALE; GLUCAGON; GLUCOSE; IMMUNOHISTOCHEMISTRY; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MALE; MICE; MICROSCOPY, FLUORESCENCE; PANCREAS; PROGLUCAGON; RADIOIMMUNOASSAY; RATS; RATS, WISTAR; REGENERATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STREPTOZOCIN; TIME FACTORS;

EID: 33645868980     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2005-0396     Document Type: Article

References (54)

1. Gepts W, de Mey J 1978 Islet cell survival determined by morphology. An immunocytochemical study of the islet of Langerhans in juvenile diabetes mellitus. Diabetes 27(Suppl 1):251-261
2. Volk BW, Wellman KF 1985 The pancreas in idiopathic diabetes. In: Volk BW, Arquilla ER, eds. The diabetic pancreas. 2nd ed. New York: Plenum Press; 353
3. Hess D, Li L, Sakano S, Hill DJ, Strutt B, Thyssen S, Gray D, Bhatia M 2003 Bone marrow derived stem cells rescue hyperglycemia by regeneration of recipient islets. Nat Biotechnol 21:763-770
4. Kodoma S, Kuhtreiber W, Fujimura S, Dale EA, Faustman DL 2003 Islet regeneration during the reversal of autoimmune diabetes in NOD mice. Science 302:1223-1227
5. Edlund H 2001 Developmental biology of the pancreas. Diabetes 50(Suppl 1):S5-S9
6. Soria B 2001 In vitro differentiation of pancreatic β-cells. Differentiation 68:205-219
7. Habener JF, Kemp DM, Thomas MK 2005 Minireview: transcriptional regulation in pancreatic development. Endocrinology 146:1025-1034
8. Scaglia L, Cahill CJ, Finegood DT, Bonner-Weir S 1997 Apoptosis participates in the remodeling of the endocrine pancreas in the neonatal rat. Endocrinology 138:1736-1741
9. Petrik J, Arany E, McDonald TJ, Hill DJ 1998 Apoptosis in the pancreatic islet cells of the neonatal rat is associated with a reduced expression of insulin-like growth factor II that may at as a survival factor. Endocrinology 139:2994-3004
10. + cells are islet progenitors and are distinct from duct progenitors. Development 129:2447-2457
11. Mellitzer G, Martin M, Sidhoum-Jenny M, Orvain C, Barths J, Seymour PA, Sander M, Gradwohl G 2004 Pancreatic islet progenitor cells in neurogenin 3-yellow fluorescent protein knock-add-on mice. Mol Endocrinol 18:2765-2776
12. Joanette E, Reusens B, Arany E, Thyssen S, Remacle RC, Hill DJ 2004 Low protein diet during early life causes a reduction in the number of cells immunopositive for nestin and CD34 in both pancreatic ducts and islets in the rat. Endocrinology 145:3004-3013
13. Treutelaar MK, Skidmore JM, Dias-Leme CL, Hara M, Zhang L, Simeone D, Martin DM, Burant CF 2003 Nestin lineage cells contribute to the microvasculature but not endocrine cells of the islet. Diabetes 52:2503-2512
14. Delacour A, Nepote V, Trumpp A, Herrera PL 2004 Nestin expression in pancreatic exocrine cell lineages. Mech Dev 121:3-14
15. Herrera PL 2002 Defining the cell lineages of the islets of Langerhans using transgenic mice. Int J Dev Biol 46:97-103
16. Herrera PL 2000 Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages. Development 127:2317-2322
17. Fernandes A, King LC, Guz Y, Stein R, Wright CV, Teitelman G 1997 Differentiation of new insulin-producing cells is induced by injury in adult pancreatic islets. Endocrinology 138:1750-1762
18. Montanya E, Nacher V, Biarnes M, Soler J 2000 Linear correlation between β-cell mass and body weight throughout the lifespan in Lewis rats. Diabetes 49:1341-1346
19. Bonner-Weir S, Deery D, Leahy JL, Weir GC 1989 Compensatory growth of pancreatic β-cells in adult rats after short-term glucose infusion. Diabetes 38:49-53
20. Rosenberg L, Duguid WP, Vinik AL 1989 The effect of cellophane wrapping of the pancreas in the Syrian golden hamster: autoradiographic observations. Pancreas 4:31-37
21. Prado ML, Cruz AR 1983 Adaptation of the endocrine tissue of rat pancreas after partial pancreatectomy - a morphometric study. Acta Anat 116:346-352
22. Portha B, Blondel O, Serradas P, McEvoy R, Giroix MH, Kergoat M, Bailbe D 1989 The rat models of non-insulin dependent diabetes induced by neonatal streptozotocin. Diabete Metab 15:61-75
23. Movassat J, Saulnier C, Portha B 1997 Insulin administration enhances growth of the β-cell mass in streptozotocin-treated newborn rats. Diabetes 46:1445-1452
24. Bonner-Weir S, Trent DF, Honey RN, Weir GC 1981 Responses of neonatal rat islets to streptozotocin: limited B-cell regeneration and hyperglycemia. Diabetes 30:64-69
25. Guz Y, Nasir I, Teitelman G 2001 Regeneration of pancreatic β-cells from intra-islet precursor cells in an experimental model of diabetes. Endocrinology 142:4956-4968
26. Dor Y, Brown J, Martinez OI, Melton DA 2004 Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation. Nature 429:41-46
27. Seaberg RM, Smukler S, Kieffer TJ, Enikolopov G, Asghar Z, Wheeler MB, Korbutt G, van der Kooy D 2004 Clonal identification of multipotent precursors from adult mouse pancreas that generate neural and pancreatic lineages. Nat Biotech 22:1115-1124
28. Hsu SM, Raine L, Fanger H 1981 Use of avidin-biotin peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabelled antibody (PAP) procedures. J Histochem Cytochem 29:577-580
29. Bock T, Pakkenberg B, Buschard K 2003 Increased islet volume but unchanged islet number in ob/ob mice. Diabetes 52:1716-1722
30. Bock T, Kynel A, Pakkenberg B, Buschard K 2003 The postnatal growth of the β-cell mass in pigs. J Endocrinol 179:245-252
31. Wang R, Li J, Yashpal N 2004 Phenotypic analysis of c-kit expression in epithelial monolayers derived from postnatal rat pancreatic islets. J Endocrinol 182:113-122
32. Jensen J, Serup P, Karlsen C, Nielsen TF, Madsen OD 1996 mRNA profiling of rat islet tumors reveals nkx 6.1 as a β-cell-specific homeodomain transcription factor. J Biol Chem 27:18749-18785
33. Lindqvist N, Vidal-Sanz M, Hallbook F 2002 Single cell RT-PCR analysis of tyrosine kinase receptor expression in adult rat retinal ganglion cells isolated by retinal sandwiching. Brain Res Brain Res Protoc 10:75-83
34. Gelling RW, Du XQ, Dichmann DS, Romer J, Huang H, Cui L, Obici S, Tang B, Holst JJ, Fledelius C, Johansen PB, Rossetti L, Jelicks LA, Serup P, Nishimura E, Charron MJ 2003 Lower blood glucose, hyperglucagonemia, and pancreatic α cell hyperplasia in glucagon receptor knockout mice. Proc Natl Acad Sci USA 100:1438-1443
35. Detrillaux MC, Portha B, Roze C, Hollande E 1982 Ultrastructural study of pancreatic B cell regeneration in newborn rats after destruction by streptozotocin. Virch Arch 39:173-185
36. Wang RN, Bouwens L.Koppel G 1994 β Cell proliferation in normal and streptozotocin-treated newborn rats: site, dynamics and capacity. Diabetologia 37:1088-1096
37. Nagasao J, Yoshioka K, Amasaki H, Mutoh K 2004 Expression of nestin and IGF-I in rat pancreas after streptozotocin administration. Anat Histol Embryol 33:1-4
38. Chen L, Komiya I, Inman L, McCorkle K, Alam T, Unger RH 1989 Molecular and cellular responses of islets during perturbations of glucose homeostasis determined by in situ hybridization histochemistry. Proc Natl Acad Sci USA 86:1367-1371
39. Raskin P, Aydin I, Unger RH 1976 Effect of insulin on the exaggerated glucagon response to arginine stimulation in diabetes mellitus. Diabetes 25:227-229
40. Vincent M, Guz Y, Rozenberg M, Webb G, Furuta M, Steiner D, Teitelman G 2003 Abrogation of protein convertase 2 activity results in delayed islet cell differentiation and maturation, increased α-cell proliferation, and islet neogenesis. Endocrinology 144:4061-4069
41. Stoffers DA 2004 The development of β-cell mass: recent progress and potential role of GLP-1. Horm Metab Res 36:811-821
42. Bulotta A, Farilla L, Hui H, Perfetti R 2004 The role of GLP-1 in the regulation of islet cell mass. Cell Biochem Biophys 40(Suppl 3):65-78
43. Abraham EJ, Leech CA, Lin JC, Zulewski H, Habener JF 2002 Insulinotropic hormone glucagon-like peptide-1 differentiation of human pancreatic islet-derived progenitor cells into insulin-producing cells. Endocrinology 143:3152-3161
44. Dhanvantari S, Seidah NG, Brubaker PL 1996 Role of prohormone convertases in the tissue specific processing of proglucagon. Mol Endocrinol 10:342-355
45. Scopsi L, Gullo M, Rilke F, Martin S, Steiner DF 1995 Pro-protein convertases (PC1/3 and PC2) in normal and neoplastic human tissues: their use as markers of neuroendocrine differentiation. J Clin Endocrinol Metab 80:294-301
46. Zhu X, Zhou A, Dey A, Norrbom C, Caroll R, Zhang C, Laurent V, Lindberg I, Ugleholdt R, Holst JJ, Steiner DF 2002 Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects. Proc Natl Acad Sci USA 99:10293-10298
47. Furuta M, Yano H, Zhou A, Rouille Y, Holst JJ, Carroll R, Ravazzola M, Orci L, Furuta H, Steiner DF 1997 Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2. Proc Natl Acad Sci USA 94:6646-6651
48. Nie Y, Nakashima M, Brubaker PL, Li QL, Perfetti R, Jansen E, Zambre Y, Pipeleers D, Friedman TC 2000 Regulation of pancreatic PC1 and PC2 associated with increased glucagon-like peptide 1 in diabetic rats. J Clin Invest 105:955-965
49. Kreymann B, Ghatei MA, Domin J, Kanse S, Bloom SR 1991 Developmental patterns of glucagon-like peptide-1-(7-36) amide and peptide-YY in rat pancreas and gut. Endocrinology 129:1001-1005
50. DeLeon DD, Deng S, Madani R, Ahima RS, Drucker DJ, Stoffers DA 2003 Role of endogenous glucagon-like peptide-1 in islet regeneration after partial pancreatectomy. Diabetes 52:365-371
51. Ferrand N, Astesano A, Phan H-H, Lelong C, Rosselin G 1995 Dynamics of pancreatic cell growth and differentiation during diabetes reversion in STZ-treated newborn rats. Am J Physiol 269:C1250-C1264
52. Wang R, Li J, Yashpal N, Gao N 2005 Nestin expression and clonal analysis of islet-derived epithelial monolayers: insight into nestin-expressing cell heterogeneity and differentiation potential. J Endocrinol 184:329-339
53. Gershengorn MC, Hardikar AA, Wei C, Geras-Raaka E, Marcus-Samuels B, Raaka BM 2004 Epithelial to mesenchymal transition generates proliferative human islet precursor cells. Science 306:2261-2264
54. Banerjee M, Bhonde RR 2003 Islet generation from intra islet precursor cells of diabetic pancreas: In vitro studies depicting in vivo differentiation. J Pancreas 4:137-145