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Volumn 301, Issue 5, 2011, Pages

Exendin-4 upregulates the expression of Wnt-4, a novel regulator of pancreatic β-cell proliferation

Author keywords

Diabetes; Glucagon like peptide 1

Indexed keywords

ANTIDIABETIC AGENT; EXENDIN 4; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; MESSENGER RNA; SECRETED FRIZZLED RELATED PROTEIN 4; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR 7 LIKE 2; TUMOR NECROSIS FACTOR ALPHA; WNT10B PROTEIN; WNT4 PROTEIN;

EID: 80054961220     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00144.2011     Document Type: Article
Times cited : (29)

References (30)
  • 4
    • 33747339465 scopus 로고    scopus 로고
    • Wnt signaling: Multiple pathways, multiple receptors, and multiple transcription factors
    • Gordon MD, Nusse R. Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors. J Biol Chem 281: 22429-22433, 2006.
    • (2006) J Biol Chem , vol.281 , pp. 22429-22433
    • Gordon, M.D.1    Nusse, R.2
  • 6
    • 77949272169 scopus 로고    scopus 로고
    • Thiazolidinediones increase the wingless-type MMTV integration site family (WNT) inhibitor Dickkopf-1 in adipocytes: A link with osteogenesis
    • Gustafson B, Eliasson B, Smith U. Thiazolidinediones increase the wingless-type MMTV integration site family (WNT) inhibitor Dickkopf-1 in adipocytes: a link with osteogenesis. Diabetologia 53: 536-540, 2010.
    • (2010) Diabetologia , vol.53 , pp. 536-540
    • Gustafson, B.1    Eliasson, B.2    Smith, U.3
  • 7
    • 0036842027 scopus 로고    scopus 로고
    • Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation
    • Heller RS, Dichmann DS, Jensen J, Miller C, Wong G, Madsen OD, Serup P. Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation. Dev Dyn 225: 260-270, 2002.
    • (2002) Dev Dyn , vol.225 , pp. 260-270
    • Heller, R.S.1    Dichmann, D.S.2    Jensen, J.3    Miller, C.4    Wong, G.5    Madsen, O.D.6    Serup, P.7
  • 9
    • 51249114496 scopus 로고    scopus 로고
    • The WNT signalling pathway and diabetes mellitus
    • Jin T. The WNT signalling pathway and diabetes mellitus. Diabetologia 51: 1771-1780, 2008.
    • (2008) Diabetologia , vol.51 , pp. 1771-1780
    • Jin, T.1
  • 10
    • 72449185129 scopus 로고    scopus 로고
    • Regulation of wingless-type MMTV integration site family (WNT) signalling in pancreatic islets from wild-type and obese mice
    • Krutzfeldt J, Stoffel M. Regulation of wingless-type MMTV integration site family (WNT) signalling in pancreatic islets from wild-type and obese mice. Diabetologia 53: 123-127, 2010.
    • (2010) Diabetologia , vol.53 , pp. 123-127
    • Krutzfeldt, J.1    Stoffel, M.2
  • 11
    • 23944479411 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 protects beta cells from cytokine-induced apoptosis and necrosis: Role of protein kinase B
    • Li L, El-Kholy W, Rhodes CJ, Brubaker PL. Glucagon-like peptide-1 protects beta cells from cytokine-induced apoptosis and necrosis: role of protein kinase B. Diabetologia 48: 1339-1349, 2005.
    • (2005) Diabetologia , vol.48 , pp. 1339-1349
    • Li, L.1    El-Kholy, W.2    Rhodes, C.J.3    Brubaker, P.L.4
  • 12
    • 43749120731 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 activation of TCF7L2-dependent Wnt signaling enhances pancreatic beta cell proliferation
    • Liu Z, Habener JF. Glucagon-like peptide-1 activation of TCF7L2-dependent Wnt signaling enhances pancreatic beta cell proliferation. J Biol Chem 283: 8723-8735, 2008.
    • (2008) J Biol Chem , vol.283 , pp. 8723-8735
    • Liu, Z.1    Habener, J.F.2
  • 13
    • 54049088180 scopus 로고    scopus 로고
    • The transcription factor 7-like 2 gene and increased risk of type 2 diabetes: An update
    • Lyssenko V. The transcription factor 7-like 2 gene and increased risk of type 2 diabetes: an update. Curr Opin Clin Nutr Metab Care 11: 385-392, 2008.
    • (2008) Curr Opin Clin Nutr Metab Care , vol.11 , pp. 385-392
    • Lyssenko, V.1
  • 14
    • 45849093670 scopus 로고    scopus 로고
    • The what, where, when and how of Wnt/beta-catenin signaling in pancreas development
    • Murtaugh LC. The what, where, when and how of Wnt/beta-catenin signaling in pancreas development. Organogenesis 4: 81-86, 2008.
    • (2008) Organogenesis , vol.4 , pp. 81-86
    • Murtaugh, L.C.1
  • 15
    • 77957684206 scopus 로고    scopus 로고
    • Genetic variants affecting incretin sensitivity and incretin secretion
    • Mussig K, Staiger H, Machicao F, Haring HU, Fritsche A. Genetic variants affecting incretin sensitivity and incretin secretion. Diabetologia 53: 2289-2297, 2010.
    • (2010) Diabetologia , vol.53 , pp. 2289-2297
    • Mussig, K.1    Staiger, H.2    Machicao, F.3    Haring, H.U.4    Fritsche, A.5
  • 16
    • 0037428472 scopus 로고    scopus 로고
    • Transcriptional activation of the proglucagon gene by lithium and beta-catenin in intestinal endocrine L cells
    • Ni Z, Anini Y, Fang X, Mills G, Brubaker PL, Jin T. Transcriptional activation of the proglucagon gene by lithium and beta-catenin in intestinal endocrine L cells. J Biol Chem 278: 1380-1387, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 1380-1387
    • Ni, Z.1    Anini, Y.2    Fang, X.3    Mills, G.4    Brubaker, P.L.5    Jin, T.6
  • 17
    • 0032403191 scopus 로고    scopus 로고
    • Nrf1 in a complex with fosB, c-jun, junD and ATF2 forms the AP1 component at the TNF alpha promoter in stimulated mast cells
    • Novotny V, Prieschl EE, Csonga R, Fabjani G, Baumruker T. Nrf1 in a complex with fosB, c-jun, junD and ATF2 forms the AP1 component at the TNF alpha promoter in stimulated mast cells. Nucleic Acids Res 26: 5480-5485, 1998.
    • (1998) Nucleic Acids Res , vol.26 , pp. 5480-5485
    • Novotny, V.1    Prieschl, E.E.2    Csonga, R.3    Fabjani, G.4    Baumruker, T.5
  • 18
    • 67349270566 scopus 로고    scopus 로고
    • Translating TCF7L2: From gene to function
    • Pearson ER. Translating TCF7L2: from gene to function. Diabetologia 52: 1227-1230, 2009.
    • (2009) Diabetologia , vol.52 , pp. 1227-1230
    • Pearson, E.R.1
  • 20
    • 77957678974 scopus 로고    scopus 로고
    • Anti-inflammatory action of exendin-4 in human islets is enhanced by phosphodiesterase inhibitors: Potential therapeutic benefits in diabetic patients
    • Pugazhenthi U, Velmurugan K, Tran A, Mahaffey G, Pugazhenthi S. Anti-inflammatory action of exendin-4 in human islets is enhanced by phosphodiesterase inhibitors: potential therapeutic benefits in diabetic patients. Diabetologia 53: 2357-2368, 2010.
    • (2010) Diabetologia , vol.53 , pp. 2357-2368
    • Pugazhenthi, U.1    Velmurugan, K.2    Tran, A.3    Mahaffey, G.4    Pugazhenthi, S.5
  • 21
    • 0026499517 scopus 로고
    • The regulation of the human tumor necrosis factor alpha promoter region in macrophage, T cell, and B cell lines
    • Rhoades KL, Golub SH, Economou JS. The regulation of the human tumor necrosis factor alpha promoter region in macrophage, T cell, and B cell lines. J Biol Chem 267: 22102-22107, 1992.
    • (1992) J Biol Chem , vol.267 , pp. 22102-22107
    • Rhoades, K.L.1    Golub, S.H.2    Economou, J.S.3
  • 24
    • 77955554379 scopus 로고    scopus 로고
    • Wingless-type MMTV integration site family (WNT) signalling in pancreatic beta cells-more complex than expected
    • Schinner S. Wingless-type MMTV integration site family (WNT) signalling in pancreatic beta cells-more complex than expected. Diabetologia 53: 2073-2075, 2010.
    • (2010) Diabetologia , vol.53 , pp. 2073-2075
    • Schinner, S.1
  • 26
    • 36649015410 scopus 로고    scopus 로고
    • Regulation of insulin secretion, glucokinase gene transcription and beta cell proliferation by adipocyte-derived Wnt signalling molecules
    • Schinner S, Ulgen F, Papewalis C, Schott M, Woelk A, Vidal-Puig A, Scherbaum WA. Regulation of insulin secretion, glucokinase gene transcription and beta cell proliferation by adipocyte-derived Wnt signalling molecules. Diabetologia 51: 147-154, 2008.
    • (2008) Diabetologia , vol.51 , pp. 147-154
    • Schinner, S.1    Ulgen, F.2    Papewalis, C.3    Schott, M.4    Woelk, A.5    Vidal-Puig, A.6    Scherbaum, W.A.7
  • 27
    • 36649015410 scopus 로고    scopus 로고
    • Regulation of insulin secretion, glucokinase gene transcription and beta cell proliferation by adipocyte-derived Wnt signalling molecules
    • Schinner S, Ulgen F, Papewalis C, Schott M, Woelk A, Vidal-Puig A, Scherbaum WA. Regulation of insulin secretion, glucokinase gene transcription and beta cell proliferation by adipocyte-derived Wnt signalling molecules. Diabetologia 51: 147-154, 2008.
    • (2008) Diabetologia , vol.51 , pp. 147-154
    • Schinner, S.1    Ulgen, F.2    Papewalis, C.3    Schott, M.4    Woelk, A.5    Vidal-Puig, A.6    Scherbaum, W.A.7
  • 28
    • 40949141938 scopus 로고    scopus 로고
    • Transcription factor 7-like 2 regulates beta-cell survival and function in human pancreatic islets
    • Shu L, Sauter NS, Schulthess FT, Matveyenko AV, Oberholzer J, Maedler K. Transcription factor 7-like 2 regulates beta-cell survival and function in human pancreatic islets. Diabetes 57: 645-653, 2008.
    • (2008) Diabetes , vol.57 , pp. 645-653
    • Shu, L.1    Sauter, N.S.2    Schulthess, F.T.3    Matveyenko, A.V.4    Oberholzer, J.5    Maedler, K.6
  • 29
    • 0346363760 scopus 로고    scopus 로고
    • The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma
    • Tian E, Zhan F, Walker R, Rasmussen E, Ma Y, Barlogie B, Shaughnessy JD Jr. The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma. N Engl J Med 349: 2483-2494, 2003.
    • (2003) N Engl J Med , vol.349 , pp. 2483-2494
    • Tian, E.1    Zhan, F.2    Walker, R.3    Rasmussen, E.4    Ma, Y.5    Barlogie, B.6    Shaughnessy Jr., J.D.7
  • 30
    • 12544254474 scopus 로고    scopus 로고
    • TCF-4 mediates cell type-specific regulation of proglucagon gene expression by beta-catenin and glycogen synthase kinase-3beta
    • Yi F, Brubaker PL, Jin T. TCF-4 mediates cell type-specific regulation of proglucagon gene expression by beta-catenin and glycogen synthase kinase-3beta. J Biol Chem 280: 1457-1464, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 1457-1464
    • Yi, F.1    Brubaker, P.L.2    Jin, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.