Glucagon-like peptide I and glucose-dependent insulinotropic polypeptide stimulate Ca2+-induced secretion in rat α-cells by a protein kinase A- mediated mechanism

Diabetes

Volumn 46, Issue 5, 1997, Pages 792-800

  Ding, Wei Guang ^a   Renström, Erik ^a   Rorsman, Patrik ^a   Buschard, Karsten ^b   Gromada, Jesper ^a  

^a NOVO NORDISK A S   (Denmark)

^b Department of Rheumatology and the Osteoporosis Research Centre   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CYCLIC AMP DEPENDENT PROTEIN KINASE; GLUCAGON; GLUCAGON LIKE PEPTIDE 1; INSULIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; EXOCYTOSIS; GLUCAGON RELEASE; HORMONE ACTION; NONHUMAN; PANCREAS ISLET ALPHA CELL; PRIORITY JOURNAL; RAT; VOLTAGE CLAMP;

EID: 0030943464     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diab.46.5.792     Document Type: Article

References (35)

1. Ashcroft FM, Rorsman P: Electrophysiology of pancreatic islet cells. In The Electrophysiology of Neuroendocrine Cells. Hescheler J, Scherübl H, Eds. Boca Raton, FL, CRC Press, 1995, p. 207-243
2. Moens K, Heimberg H, Flamez D, Huypens P, Quartier E, Ling Z, Pipeleers D, Gremlich S, Thorens B, Schuit F: Expression and functional activity of glucagon, glucagon-like peptide 1, and glucose-dependent insulinotropic peptide receptors in rat pancreatic islet cells. Diabetes 45:257-261, 1996
3. Heller RS, Kieffer TJ, Habener JF: Insulinotropic glucagon-like peptide I receptor expression in glucagon-producing α-cells of the rat endocrine pancreas. Diabetes 46:785-791, 1997
4. Neher E, Marty A: Discrete changes of cell membrane capacitance observed under conditions of enhanced secretion in bovine adrenal chromaffin cells. Proc Natl Acad Sci USA 79:6712-6716, 1982
5. Josefsen K, Stenvang JP, Kindmark H, Berggren P-O, Horn T, Kjœr T, Buschard K: Fluorescence-activated cell sorted rat islet cells and studies of the insulin secretory process. J Endocrin 149:145-154, 1996
6. Rorsman P, Ashcroft FM, Berggren P-O: Regulation of glucagon release from pancreatic α-cells. Biochem Pharmacol 41:1783-1790, 1991
7. Rorsman P, Hellman B: Voltage-activated currents in guinea pig pancreatic α2 cells. J Gen Physiol 91:223-242, 1988
8. Ämmälä C, Eliasson L, Bokvist K, Larsson O, Ashcroft FM, Rorsman P: Exocytosis elicited by action potentials and voltage-clamp calcium currents in individual mouse pancreatic β-cells. J Physiol 472:665-688, 1993
9. Rorsman P, Trube G: Calcium and delayed potassium currents in mouse pancreatic β-cells under voltage-clamp conditions. J Physiol 374:531-550, 1986
10. Horn R, Marty A: Muscarinic activation of ionic currents measured by a new whole-cell recording method. J Gen Physiol 92:145-159, 1988
11. Rae J, Cooper K, Gates P, Watsky M: Low access resistance perforated patch recordings using amphotericin B. J Neurosci Methods 37:15-26, 1991
12. Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ: Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers Arch 391:85-100, 1981
13. Hille B: Ionic Channels of Excitable Membranes. Sunderland, MA, Sinauer Associates, 1992, p. 1-20
14. Bishop AE, Polak JM: The anatomy, organization and ultrastructure of the islets of Langerhans. In Textbook of Diabetes. Pickup J, Williams G, Eds. Oxford, Blackwell Scientific, 1991, p. 57-71
15. Gromada J, Dissing S, Rorsman P: Desensitization of glucagon-like peptide 1 receptors in insulin-secreting βTC3 cells: role of PKA-independent mechanisms. Br J Pharmacol 118:769-775, 1996
16. Widmann C, Dolci W, Thorens B: Agonist-induced internalization and recycling of the glucagon-like peptide-1 receptor in transfected fibroblasts and in insulinomas. Biochem J 310:203-214, 1995
17. Widmann C, Dolci W, Thorens B: Desensitization and phosphorylation of the glucagon-like peptide-1 (GLP-1) receptor by GLP-1 and 4-phorbol 12-myristate 13-acetate. Mol Endocrinol 10:62-75, 1996
18. Thorens B: Glucagon-like peptide-1 and control of insulin secretion. Diabetes Metab 21:311-318, 1995
19. Fehmann HC, Göke R, Göke B: Cell and molecular biology of the incretin hormones glucagon-like peptide-1 and glucose-dependent insulin releasing polypeptide. Endocrine Rev 16:390-410, 1995
20. De Wit JW, Hekstra B, Jastorff B, Stec VJ, Baraniak J, Van Driel R, Van Haastrert JH: Inhibitory action of certain cyclophosphate derivates of cAMP on cAMP-dependent protein Kinases. Eur J Biochem 142:255-260, 1984
21. D'Alessio DA, Fujimoto WF, Ensinck JW: Effects of glucagonlike peptide 1-(7-36) on release of insulin, glucagon, and somatostatin by rat pancreatic islet cell monolayer cultures. Diabetes 38:1534-1538, 1989
22. Heller RS, Aponte GW: Intra-islet regulation of hormone secretion by glucagon-like peptide-1-(7-36)amide. Am J Physiol 269:G852-G860, 1995
23. Fehmann HC, Habener JF: Functional receptors for the insulinotropic hormone glucagon-like peptide-1(7-37) on a somatostatin secreting cell line. FEBS Lett 279:335-340, 1991
24. Seaquist ER, Armstrong MB, Gettys TW, Walseth TF: Somatostatin selectively couples to G(o-alpha) in HIT-T15 cells. Diabetes 44:85-89, 1995
25. Schuit FC, Derde MP, Pipeleers DG: Sensitivity of pancreatic α and β cells to somatostatin. Diabetologia 32:207-212, 1989
26. Ørskov C, Poulsen SS: Glucagonlike peptide-1-(7-36)-amide receptors only in islets of Langerhans. Diabetes 40:1292-1296, 1991
27. Renström E, Ding W-G, Bokvist K, Rorsman P: Neurotransmitter-induced inhibition of exocytosis in insulin-secreting-cells by activation of calcineurin. Neuron 17:513-522, 1996
28. Komatsu R, Matsuyama T, Namba M, Watanabe N, Itoh, H, Kono N, Tarui S: Glucagonostatic and insulinotropic action of glucagonlike peptide 1-(7-36)-amide. Diabetes 38:902-905, 1989
29. Kawai K, Suzuki S, Ohashi S, Mukai H, Ohmori H, Murayama Y, Yamashita K: Comparison of the effects of glucagon-like peptide-1-(1-37) and -(7-37) and glucagon on islet hormone release from isolated perfused canine and rat pancreases. Endocrinology 124:1768-1773, 1989
30. Nauck MA, Heimesaat MM, Ørskov C, Holst JJ, Ebert R, Creutzfeldt W: Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus. J Clin Invest 91:301-307, 1993
31. Fehmann HC, Strowski M, Lankatbuttgereit B, Göke B: Molecular and functional-characterization of insulin-receptors present on hamster glucagonoma cells. Digestion 55:214-220, 1994
32. van Schravendijk CFH, Fories A, Hooghe-Peters EL, Rogiers V, De Meyts P, Sodoyeez JC, Pipeleers D: Pancreatic hormone receptors on islet cells. Endocrinology 117:841-848, 1985
33. 2-cells by insulin/glucose and amino acids. Biophys Biochim Acta 1310:212-216, 1996
34. Holst JJ, Ørskov C: Glucagon and other proglucagon-derived peptides. In Gut Peptides: Biochemistry and Physiology. Walsh JH, Dockray GJ, Eds. New York, Raven, 1994, p. 305-340
35. Kreymann B, Williams GW, Ghatei MA, Bloom SR: Glucagon-like peptide-1 7-36: a physiological incretin in man. Lancet 2:1300-1304, 1987