PET radiotracers for molecular imaging of serotonin 5-HT1A receptors

Current Medicinal Chemistry

Volumn 21, Issue 1, 2014, Pages 70-81

  Billard, T ^a,b   Le Bars, D ^a,b   Zimmer, L ^a,b  

^a CERMEP IMAGERIE DU VIVANT   (France)

^b UNIVERSITÉ LYON 1   (France)

Author keywords

5 HT1A receptor.; Agonist; Antagonist; Neurotransmission; Positron emission tomography; Radiopharmaceutical

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; ANTIDEPRESSANT AGENT; ANXIOLYTIC AGENT; BUSPIRONE; CPC 222 C 11; CUMI 101 C 11; DESMETHYL N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE CARBONYL C 11; F 15599 F 18; FLUOROCYCLOHEXYL N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE F 18; MPPF F 18; N (6 BROMO PYRIDIN 2 YL) N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE CARBONYL C 11; N (6 FLUORO PYRIDIN 2 YL) N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE CARBONYL C 11; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE CARBONYL C 11; N TERT BUTYL 3 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL] 2 PHENYLPROPIONAMIDE; SEROTONIN; SEROTONIN 1A AGONIST; SEROTONIN 1A ANTAGONIST; SEROTONIN 1A RECEPTOR; SEROTONIN UPTAKE INHIBITOR; TRACER; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; BLOOD BRAIN BARRIER; CLINICAL TRIAL (TOPIC); DOSIMETRY; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG METABOLISM; DRUG PENETRATION; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG UPTAKE; FEEDING BEHAVIOR; HUMAN; ISOTOPE LABELING; LIGAND BINDING; LIPOPHILICITY; MOLECULAR IMAGING; MOOD; NONHUMAN; PARTIAL AGONISM; POSITRON EMISSION TOMOGRAPHY; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; PSYCHOPHARMACOLOGY; RADIOACTIVITY; RECEPTOR BINDING; RECEPTOR DENSITY; REGULATORY MECHANISM; SENSORY SYSTEM; SEROTONINERGIC TRANSMISSION; SLEEP; WAKEFULNESS;

ANIMALS; HUMANS; MOLECULAR IMAGING; POSITRON-EMISSION TOMOGRAPHY; RADIOACTIVE TRACERS; RECEPTOR, SEROTONIN, 5-HT1A; SEROTONIN 5-HT1 RECEPTOR AGONISTS; SEROTONIN 5-HT1 RECEPTOR ANTAGONISTS;

EID: 84889584181     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/09298673113209990215     Document Type: Article

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