[carbonyl-11C]Desmethyl-WAY-100635 (DWAY) is a potent and selective radioligand for central 5-HT(1A) receptors in vitro and in vivo

European Journal of Nuclear Medicine

Volumn 25, Issue 4, 1998, Pages 338-346

  Pike, Victor W ^a   Halldin, Christer ^b   McCarron, Julie A ^a   Lundkvist, Camilla ^b   Hirani, Ella ^a   Olsson, Hans ^b   Hume, Susan P ^a   Karlsson, Per ^b   Osman, Safiye ^a   Swahn, Carl Gunnar ^b   Hall, Håkan ^b   Wikström, Håkan ^c   Mensonidas, Marguerite ^c   Poole, Keith G ^a   Farde, Lars ^b  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

5 HT(1A) receptors; carbonyl 11C Desmethyl WAY 100635; DWAY; Positron emission tomography; Radioligand

Indexed keywords

CARBON 11; RADIOLIGAND; SEROTONIN 1A RECEPTOR; SEROTONIN AGONIST; CARBON; DESMETHYL WAY 100635; DESMETHYL-WAY 100635; DIAGNOSTIC AGENT; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; PIPERAZINE DERIVATIVE; PYRIDINE DERIVATIVE; SEROTONIN 1 RECEPTOR; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; AUTORADIOGRAPHY; BRAIN REGION; CEREBELLUM; FRONTAL CORTEX; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; INTRAVENOUS DRUG ADMINISTRATION; MONKEY; NEOCORTEX; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RAPHE NUCLEUS; RAT; RECEPTOR DENSITY; TIME; ANIMAL; BRAIN; COMPUTER ASSISTED EMISSION TOMOGRAPHY; ISOTOPE LABELING; MACACA; MALE; METABOLISM; SCINTISCANNING; SPRAGUE DAWLEY RAT; TISSUE DISTRIBUTION;

ANIMALS; AUTORADIOGRAPHY; BRAIN; CARBON RADIOISOTOPES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; ISOTOPE LABELING; MACACA FASCICULARIS; MALE; PIPERAZINES; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; SEROTONIN ANTAGONISTS; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 14444272981     PISSN: 03406997     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002590050230     Document Type: Article

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