Remotely-controlled production of the 5-HT(1A) receptor radioligand, [carbonyl-11C]WAY-100635, via 11C-carboxylation of an immobilized Grignard reagent

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 38, Issue 10, 1996, Pages 941-953

  McCarron, Julie A ^a   Turton, David R ^a   Pike, Victor W ^a   Poole, Keith G ^a  

^a MRC CLINICAL SCIENCES CENTRE   (United Kingdom)

Author keywords

5 HT(1A) receptors; 11C carboxylation; Immobilized Grignard reagent; PET; Radioligand; carbonyl 11C WAY 100635

Indexed keywords

CARBON DIOXIDE; CHLORINE COMPOUNDS; POLYPROPYLENES; POSITRON EMISSION TOMOGRAPHY; RADIOACTIVITY; REMOTE CONTROL;

11C-CARBOXYLATION; 5-HT(1A) RECEPTOR; CARBON-11; GRIGNARD REAGENT; HUMAN BRAIN; IMMOBILIZED GRIGNARD REAGENT; PYRIDYL; RADIOLIGANDS; [CARBONYL; [CARBONYL-11C]WAY-100635;

CARBOXYLATION;

CARBON 11; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; RADIOLIGAND; SEROTONIN 1A RECEPTOR;

ARTICLE; DRUG PURIFICATION; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOTOPE LABELING; REACTION ANALYSIS;

EID: 0029798822     PISSN: 03624803     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1344(199610)38:10<941::AID-JLCR906>3.0.CO;2-Y     Document Type: Article

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