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Volumn 23, Issue 5, 1996, Pages 627-634

Characterization of the radioactive metabolites of the 5-HT(1A) receptor radioligand, [O-methyl-11C]WAY-100635, in monkey and human plasma by HPLC: Comparison of the behaviour of an identified radioactive metabolite with parent radioligand in monkey using PET

(15) Osman, Safiye a Lundkvist, Camilla b Pike, Victor W a Halldin, Christer b McCarron, Julie A a Swahn, Carl Gunnar b Ginovart, Natalie b Luthra, Sajinder K a Bench, Christopher J a,c Grasby, Paul M a Wikström, Håkan d Barf, Tjeerd d Cliffe, Ian A e,f Fletcher, Allan e,f Farde, Lars b

a HAMMERSMITH HOSPITAL (United Kingdom)

b KAROLINSKA INSTITUTE (Sweden)

c IMPERIAL COLLEGE SCHOOL OF MEDICINE (United Kingdom)

d UNIVERSITY OF GRONINGEN (Netherlands)

e PFIZER INC (United States)

f Cerebrus Limited (United Kingdom)

Author keywords

5 HT(1A) receptor; Antagonist; Radioactive metabolites; Radioligand; O methyl 11C WAY 100635

Indexed keywords

CARBON 11; DRUG METABOLITE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; PIPERAZINE DERIVATIVE; SEROTONIN ANTAGONIST;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; BRAIN; CONTROLLED STUDY; HUMAN TISSUE; INTRAVENOUS DRUG ADMINISTRATION; METABOLISM; MONKEY; NONHUMAN; POSITRON EMISSION TOMOGRAPHY;

EID: 0345108066 PISSN: 09698051 EISSN: None Source Type: Journal
DOI: 10.1016/0969-8051(96)00061-3 Document Type: Article

Times cited : (87)

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