Radiosynthesis and preclinical evaluation of 18F-F13714 as a fluorinated 5-HT 1A receptor agonist radioligand for PET neuroimaging

Journal of Nuclear Medicine

Volumn 53, Issue 6, 2012, Pages 969-976

  Lemoine, Laëtitia ^a   Becker, Guillaume ^a,b   Vacher, Bernard ^c   Billard, Thierry ^a   Lancelot, Sophie ^a,b   Newman Tancredi, Adrian ^c   Zimmer, Luc ^a,b  

^a UNIVERSITÉ LYON 1   (France)

^b CERMEP IMAGERIE DU VIVANT   (France)

^c INSTITUT DE RECHERCHE PIERRE FABRE   (France)

Author keywords

Agonist; Cat; PET; Rat; Serotonin 1A receptor

Indexed keywords

DRUG METABOLITE; F 13714 F 18; SEROTONIN 1A RECEPTOR; TRACER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BRAIN CORTEX; CAT; CINGULATE GYRUS; CONTROLLED STUDY; DORSAL RAPHE NUCLEUS; DRUG DISTRIBUTION; DRUG PENETRATION; DRUG PURITY; DRUG SYNTHESIS; EX VIVO STUDY; HIPPOCAMPUS; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; MALE; NEUROIMAGING; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

AMINOPYRIDINES; ANIMALS; BRAIN; CATS; FLUORINE RADIOISOTOPES; ISOTOPE LABELING; MALE; PIPERIDINES; POSITRON-EMISSION TOMOGRAPHY; RADIOLIGAND ASSAY; RADIOPHARMACEUTICALS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, SEROTONIN, 5-HT1A; SEROTONIN 5-HT1 RECEPTOR AGONISTS;

EID: 84861880589     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.111.101212     Document Type: Article

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