8-OH-DPAT acts on both 5-HT1A and 5-HT7 receptors to induce hypothermia in rodents

European Journal of Pharmacology

Volumn 487, Issue 1-3, 2004, Pages 125-132

  Hedlund, Peter B ^a   Kelly, Lisa ^b   Mazur, Curt ^b   Lovenberg, Timothy ^b   Sutcliffe, J Gregor ^a   Bonaventure, Pascal ^b  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Hypothermia; In vivo; Knockout; Mouse; Serotonin; Thermoregulation

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 2A [4 (4 PHENYL 1,2,3,6 TETRAHYDROPYRIDYL)BUTYL] 2A,3,4,5 TETRAHYDROBENZO[CD]INDOL 2(1H) ONE; 3 [2 [2 (4 METHYL 1 PIPERIDINYL)ETHYL] 1 PYRROLIDINESULFONYL]PHENOL; ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; ATIPAMEZOLE; DR 4004; N TERT BUTYL 3 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL] 2 PHENYLPROPIONAMIDE; PINDOLOL; SEROTONIN 1A RECEPTOR; SEROTONIN 7 RECEPTOR; SEROTONIN AGONIST; SEROTONIN ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BODY TEMPERATURE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; FEMALE; HYPOTHERMIA; KNOCKOUT MOUSE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANIMALS; BODY TEMPERATURE; BODY TEMPERATURE REGULATION; FEMALE; HYPOTHERMIA; IMIDAZOLES; INDOLES; MICE; PHENOLS; PIPERAZINES; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, SEROTONIN, 5-HT1A; RECEPTORS, SEROTONIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; SULFONAMIDES; TELEMETRY;

EID: 1642413511     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.01.031     Document Type: Article

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