High-yield radiosynthesis and preliminary in vivo evaluation of p- [18F]MPPF, a fluoro analog of WAY-100635

Nuclear Medicine and Biology

Volumn 25, Issue 4, 1998, Pages 343-350

  Le Bars, D ^a   Lemaire, C ^b   Ginovart, N ^a   Plenevaux, A ^b   Aerts, J ^b   Brihaye, C ^b   Hassoun, W ^a   Leviel, V ^a   Mekhsian, P ^c   Weissmann, D ^c   Pujol, J F ^c   Luxen, A ^b   Comar, D ^a  

^a CERMEP IMAGERIE DU VIVANT   (France)

^b UNIVERSITY OF LIÈGE   (Belgium)

^c UNIVERSITÉ LYON 1   (France)

Author keywords

5HT1A; Antagonist; Fluorine 18; PET; Serotonin; WAY 100635

Indexed keywords

4 FLUORO N [2 [1 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N 2 PYRIDINYL BENZAMIDE F 18; FLUORINE 18; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; PIPERAZINE DERIVATIVE; SEROTONIN; SEROTONIN 1A RECEPTOR; SEROTONIN ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CAT; DRUG ACCUMULATION; DRUG FORMULATION; DRUG SYNTHESIS; INTRAVENOUS DRUG ADMINISTRATION; ISOTOPE LABELING; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RADIOISOTOPE DISTRIBUTION;

ANIMALS; BRAIN; CATS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; FLUORINE RADIOISOTOPES; MOLECULAR STRUCTURE; PIPERAZINES; PYRIDINES; QUALITY CONTROL; RADIOLIGAND ASSAY; RADIOPHARMACEUTICALS; SEROTONIN ANTAGONISTS; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0031972003     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8051(97)00229-1     Document Type: Article

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