-
1
-
-
3042683172
-
Information theory in molecular biology
-
Adami, C. (2004). Information theory in molecular biology. Phys Life Rev 1, 3-22.
-
(2004)
Phys Life Rev
, vol.1
, pp. 3-22
-
-
Adami, C.1
-
2
-
-
0347314981
-
Physical complexity of symbolic sequences
-
Adami, C., Cerf, N. J. (2000). Physical complexity of symbolic sequences. Physica D (Amsterdam) 37, 62-69.
-
(2000)
Physica D (Amsterdam)
, vol.37
, pp. 62-69
-
-
Adami, C.1
Cerf, N.J.2
-
3
-
-
8844286070
-
The place of metabolism in the origin of life
-
Anet, F.A. (2004). The place of metabolism in the origin of life. Curr Opin Chem Biol 8, 654-659.
-
(2004)
Curr Opin Chem Biol
, vol.8
, pp. 654-659
-
-
Anet, F.A.1
-
4
-
-
0344430112
-
Aptamers switch on fluorescence of triphenylmethane dyes
-
Babendure, J.R., Adams, S.R., Tsien, R.Y. (2003). Aptamers switch on fluorescence of triphenylmethane dyes. J Am Chem Soc 125, 14716-14717.
-
(2003)
J Am Chem Soc
, vol.125
, pp. 14716-14717
-
-
Babendure, J.R.1
Adams, S.R.2
Tsien, R.Y.3
-
5
-
-
2342511433
-
New RNA motifs suggest an expanded scope for riboswitches in bacterial genetic control
-
Barrick, J.E., Corbino, K.A., Winkler, W.C., Nahvi, A., Mandal, M., Collins, J., Lee, M., Roth, A., Sudarsan, N., Jona, I., Wickiser, J.K., Breaker, R.R. (2004). New RNA motifs suggest an expanded scope for riboswitches in bacterial genetic control. Proc Natl Acad Sci USA 101, 6421-6426.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 6421-6426
-
-
Barrick, J.E.1
Corbino, K.A.2
Winkler, W.C.3
Nahvi, A.4
Mandal, M.5
Collins, J.6
Lee, M.7
Roth, A.8
Sudarsan, N.9
Jona, I.10
Wickiser, J.K.11
Breaker, R.R.12
-
6
-
-
0027488624
-
Isolation of a new ribozymes from a large pool of random sequences
-
Bartel, D.P., Szostak, J.W. (1993). Isolation of a new ribozymes from a large pool of random sequences. Science 261, 1411-1418.
-
(1993)
Science
, vol.261
, pp. 1411-1418
-
-
Bartel, D.P.1
Szostak, J.W.2
-
7
-
-
0033610480
-
Quantitative analysis of receptors for adenosine nucleotides obtained via in vitro selection from a library incorporating a cationic nucleotide analog
-
Battersby, T.R., Ang, D.N., Burgstaller, P., Jurczyk, S.C., Bowser, M.T., Buchanan, D.D., Kennedy, R.T., Benner, S.A. (1999). Quantitative analysis of receptors for adenosine nucleotides obtained via in vitro selection from a library incorporating a cationic nucleotide analog. J Am Chem Soc 121, 9781-9789.
-
(1999)
J Am Chem Soc
, vol.121
, pp. 9781-9789
-
-
Battersby, T.R.1
Ang, D.N.2
Burgstaller, P.3
Jurczyk, S.C.4
Bowser, M.T.5
Buchanan, D.D.6
Kennedy, R.T.7
Benner, S.A.8
-
8
-
-
0023916814
-
RNA as an RNA polymerase: net elongation of an RNA primer catalyzed by the Tetrahymena ribozyme
-
Been, M.D., Cech, T.R. (1988). RNA as an RNA polymerase: net elongation of an RNA primer catalyzed by the Tetrahymena ribozyme. Science 238, 1412-1416.
-
(1988)
Science
, vol.238
, pp. 1412-1416
-
-
Been, M.D.1
Cech, T.R.2
-
9
-
-
0037426848
-
Synthetic biology: Act natural
-
Benner, S.A. (2003). Synthetic biology: Act natural. Nature 421, 118.
-
(2003)
Nature
, vol.421
, pp. 118
-
-
Benner, S.A.1
-
10
-
-
6944225455
-
Understanding nucleic acids using synthetic chemistry
-
Benner, S.A. (2004). Understanding nucleic acids using synthetic chemistry. Acc Chem Res 37, 784-797.
-
(2004)
Acc Chem Res
, vol.37
, pp. 784-797
-
-
Benner, S.A.1
-
11
-
-
0003000419
-
Did the RNA world exploit an expanded genetic alphabet?
-
In: The RNAWorld, 2nd edn, Gesteland, R.F., Cech, T.R., Atkins, J.F., eds. New York: Cold Spring Harbor Press
-
Benner, S.A., Burgstaller, P., Battersby, T.R., Jurczyk, S (1999). Did the RNA world exploit an expanded genetic alphabet? In: The RNAWorld, 2nd edn, Gesteland, R.F., Cech, T.R., Atkins, J.F., eds. New York: Cold Spring Harbor Press, pp. 163-181.
-
(1999)
, pp. 163-181
-
-
Benner, S.A.1
Burgstaller, P.2
Battersby, T.R.3
Jurczyk, S.4
-
12
-
-
0034696587
-
Kinetic framework for ligation by an efficient RNA ligase ribozyme
-
Bergman, N.H., Johnston, W.K., Bartel, D.P. (2000). Kinetic framework for ligation by an efficient RNA ligase ribozyme. Biochemistry 39, 3115-3123.
-
(2000)
Biochemistry
, vol.39
, pp. 3115-3123
-
-
Bergman, N.H.1
Johnston, W.K.2
Bartel, D.P.3
-
13
-
-
0346728679
-
In vitro compartmentalization by double emulsions: sorting and gene enrichment by fluorescence activated cell sorting
-
Bernath, K., Hai, M., Mastrobattista, E., Griffiths, A.D., Magdassi, S., Tawfik, D.S. (2004). In vitro compartmentalization by double emulsions: sorting and gene enrichment by fluorescence activated cell sorting. Anal Biochem 325, 151-157.
-
(2004)
Anal Biochem
, vol.325
, pp. 151-157
-
-
Bernath, K.1
Hai, M.2
Mastrobattista, E.3
Griffiths, A.D.4
Magdassi, S.5
Tawfik, D.S.6
-
14
-
-
18044391361
-
Covalent DNA display as a novel tool for directed evolution of proteins in vitro
-
Bertschinger, J., Neri, D. (2004). Covalent DNA display as a novel tool for directed evolution of proteins in vitro. Protein Eng Des Sel 17, 699-707.
-
(2004)
Protein Eng Des Sel
, vol.17
, pp. 699-707
-
-
Bertschinger, J.1
Neri, D.2
-
15
-
-
0026575221
-
Selection of single-stranded DNA molecules that bind and inhibit human thrombin
-
Bock, L.C., Griffin, L.C., Latham, J.A., Vermaas, E.H., Toole, J.J. (1992). Selection of single-stranded DNA molecules that bind and inhibit human thrombin. Nature 355, 564-566.
-
(1992)
Nature
, vol.355
, pp. 564-566
-
-
Bock, L.C.1
Griffin, L.C.2
Latham, J.A.3
Vermaas, E.H.4
Toole, J.J.5
-
16
-
-
0027946423
-
Continuous in vitro evolution of bacteriophage RNA polymerase promoters
-
Breaker, R.R., Banerji, A., Joyce, G.F. (1994). Continuous in vitro evolution of bacteriophage RNA polymerase promoters. Biochemistry 33, 11980-11986.
-
(1994)
Biochemistry
, vol.33
, pp. 11980-11986
-
-
Breaker, R.R.1
Banerji, A.2
Joyce, G.F.3
-
17
-
-
0035747243
-
Biomimetic selectivity
-
Breslow, R. (2001). Biomimetic selectivity. Chem Rec 1, 3-11.
-
(2001)
Chem Rec
, vol.1
, pp. 3-11
-
-
Breslow, R.1
-
18
-
-
0020594894
-
Pb(II)-catalysed cleavage of the sugar-phosphate backbone of yeast tRNAPhe-implications for lead toxicity and self-splicing RNA
-
Brown, R.S., Hingerty, B.E., Dewan, J.C., Klug, A. (1983). Pb(II)-catalysed cleavage of the sugar-phosphate backbone of yeast tRNAPhe-implications for lead toxicity and self-splicing RNA. Nature 303, 543-546.
-
(1983)
Nature
, vol.303
, pp. 543-546
-
-
Brown, R.S.1
Hingerty, B.E.2
Dewan, J.C.3
Klug, A.4
-
19
-
-
0027995790
-
Isolation of RNA aptamers for biological cofactors by in vitro selection
-
Burgstaller, P., Famulok, M. (1994). Isolation of RNA aptamers for biological cofactors by in vitro selection. Angew Chem Int Ed Engl 33, 1084-1087.
-
(1994)
Angew Chem Int Ed Engl
, vol.33
, pp. 1084-1087
-
-
Burgstaller, P.1
Famulok, M.2
-
20
-
-
0030833542
-
RNA aptamers to the adenosine moiety of S-adenosyl methionine: structural inferences from variations on a theme and the reproducibility of SELEX
-
Burke, D.H., Gold, L. (1997). RNA aptamers to the adenosine moiety of S-adenosyl methionine: structural inferences from variations on a theme and the reproducibility of SELEX. Nucleic Acids Res 25, 2020-2024.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 2020-2024
-
-
Burke, D.H.1
Gold, L.2
-
21
-
-
8844275985
-
Nucleic-acidtemplated synthesis as a model system for ancient translation
-
Calderone, C.T., Liu, D.R. (2004). Nucleic-acidtemplated synthesis as a model system for ancient translation. Curr Opin Chem Biol 8, 645-653.
-
(2004)
Curr Opin Chem Biol
, vol.8
, pp. 645-653
-
-
Calderone, C.T.1
Liu, D.R.2
-
22
-
-
0033485280
-
The parallel and convergent universes of polyketide synthases and nonribosomal peptide synthetases
-
Cane, D.E., Walsh, C.T. (1999). The parallel and convergent universes of polyketide synthases and nonribosomal peptide synthetases. Chem Biol 6, R319-325.
-
(1999)
Chem Biol
, vol.6
-
-
Cane, D.E.1
Walsh, C.T.2
-
23
-
-
1942489258
-
Informational complexity and functional activity of RNA structures
-
Carothers, J.M., Oestreich, S.C., Davis, J.H., Szostak, J.W. (2004). Informational complexity and functional activity of RNA structures. J Am Chem Soc 126, 5130-5135.
-
(2004)
J Am Chem Soc
, vol.126
, pp. 5130-5135
-
-
Carothers, J.M.1
Oestreich, S.C.2
Davis, J.H.3
Szostak, J.W.4
-
24
-
-
0011190457
-
A model for the RNA-catalyzed replication of RNA
-
Cech, T.R. (1986). A model for the RNA-catalyzed replication of RNA. Proc Natl Acad Sci USA 83, 4360-4363.
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 4360-4363
-
-
Cech, T.R.1
-
25
-
-
0036863325
-
Ribozymes, the first 20 years
-
Cech, T.R. (2002). Ribozymes, the first 20 years. Biochem Soc Trans 30, 1162-1166.
-
(2002)
Biochem Soc Trans
, vol.30
, pp. 1162-1166
-
-
Cech, T.R.1
-
26
-
-
0141606847
-
Combinatorial minimization and secondary structure determination of a nucleotide synthase ribozyme
-
Chapple, K.E., Bartel, D.P., Unrau, P.J. (2003). Combinatorial minimization and secondary structure determination of a nucleotide synthase ribozyme. RNA 9, 1208-1220.
-
(2003)
RNA
, vol.9
, pp. 1208-1220
-
-
Chapple, K.E.1
Bartel, D.P.2
Unrau, P.J.3
-
27
-
-
0043210727
-
TNA synthesis by DNA polymerases
-
Chaput, J.C., Szostak, J.W. (2003). TNA synthesis by DNA polymerases. J Am Chem Soc 125, 9274-9275.
-
(2003)
J Am Chem Soc
, vol.125
, pp. 9274-9275
-
-
Chaput, J.C.1
Szostak, J.W.2
-
28
-
-
0037471633
-
DNA polymerase-mediated DNA synthesis on a TNA template
-
Chaput, J.C., Ichida, J.K., Szostak, J.W. (2003). DNA polymerase-mediated DNA synthesis on a TNA template. J Am Chem Soc 125, 856-857.
-
(2003)
J Am Chem Soc
, vol.125
, pp. 856-857
-
-
Chaput, J.C.1
Ichida, J.K.2
Szostak, J.W.3
-
29
-
-
0037191747
-
Venter aims for maximum impact with minimal genome
-
Check, E. (2002). Venter aims for maximum impact with minimal genome. Nature 420, 350.
-
(2002)
Nature
, vol.420
, pp. 350
-
-
Check, E.1
-
30
-
-
4444326623
-
Evolution of a T7 RNA polymerase variant that transcribes 2'-O-methyl RNA
-
Chelliserrykattil, J., Ellington, A.D. (2004). Evolution of a T7 RNA polymerase variant that transcribes 2'-O-methyl RNA. Nat Biotechnol 22, 1155-1160.
-
(2004)
Nat Biotechnol
, vol.22
, pp. 1155-1160
-
-
Chelliserrykattil, J.1
Ellington, A.D.2
-
31
-
-
4444281964
-
The emergence of competition between model protocells
-
Chen, I.A., Roberts, R.W., Szostak, J.W. (2004). The emergence of competition between model protocells. Science 305, 1474-1476.
-
(2004)
Science
, vol.305
, pp. 1474-1476
-
-
Chen, I.A.1
Roberts, R.W.2
Szostak, J.W.3
-
32
-
-
0842313326
-
Altering the sequence specificity of HaeIII methyltransferase by directed evolution using in vitro compartmentalization
-
Cohen, H.M., Tawfik, D.S., Griffiths, A.D. (2004). Altering the sequence specificity of HaeIII methyltransferase by directed evolution using in vitro compartmentalization. Protein Eng Des Sel 17, 3-11.
-
(2004)
Protein Eng Des Sel
, vol.17
, pp. 3-11
-
-
Cohen, H.M.1
Tawfik, D.S.2
Griffiths, A.D.3
-
33
-
-
0036359632
-
Panning of antibody phage-display libraries. Standard protocols
-
Coomber, D.W. (2002). Panning of antibody phage-display libraries. Standard protocols. Methods Mol Biol 178, 133-145.
-
(2002)
Methods Mol Biol
, vol.178
, pp. 133-145
-
-
Coomber, D.W.1
-
34
-
-
1642415515
-
The direct catalytic asymmetric mannich reaction
-
Cordova, A. (2004). The direct catalytic asymmetric mannich reaction. Acc Chem Res 37, 102-112.
-
(2004)
Acc Chem Res
, vol.37
, pp. 102-112
-
-
Cordova, A.1
-
35
-
-
0037015034
-
Isolation of high-affinity GTP aptamers from partiallystructured RNA libraries
-
Davis, J.D., Szostak, J.W. (2002). Isolation of high-affinity GTP aptamers from partiallystructured RNA libraries. Proc Natl Acad Sci USA 99, 11616-11621.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 11616-11621
-
-
Davis, J.D.1
Szostak, J.W.2
-
36
-
-
0029904020
-
Solution structure of an ATP-binding RNA aptamer reveals a novel fold
-
Dieckmann, T., Suzuki, E., Nakamura, G.K., Feigon, J. (1996). Solution structure of an ATP-binding RNA aptamer reveals a novel fold. RNA 2, 628-640.
-
(1996)
RNA
, vol.2
, pp. 628-640
-
-
Dieckmann, T.1
Suzuki, E.2
Nakamura, G.K.3
Feigon, J.4
-
37
-
-
0037062949
-
The chemical repertoire of natural ribozymes
-
Doudna, J.A., Cech, T.R. (2002). The chemical repertoire of natural ribozymes. Nature 418, 222-228.
-
(2002)
Nature
, vol.418
, pp. 222-228
-
-
Doudna, J.A.1
Cech, T.R.2
-
38
-
-
0024475234
-
RNA-catalysed synthesis of complementary-strand RNA
-
Doudna, J.A., Szostak, J.W. (1989). RNA-catalysed synthesis of complementary-strand RNA. Nature 339, 519-522.
-
(1989)
Nature
, vol.339
, pp. 519-522
-
-
Doudna, J.A.1
Szostak, J.W.2
-
39
-
-
0029379551
-
Let's get specific: the relationship between specificity and affinity
-
Eaton, B.E., Gold, L., Zichi, D.A. (1995) Let's get specific: the relationship between specificity and affinity. Chem Biol 2, 633-638.
-
(1995)
Chem Biol
, vol.2
, pp. 633-638
-
-
Eaton, B.E.1
Gold, L.2
Zichi, D.A.3
-
40
-
-
0029093855
-
The secondary structure and sequence optimization of an RNA ligase ribozyme
-
Ekland, E.H., Bartel, D.P. (1995). The secondary structure and sequence optimization of an RNA ligase ribozyme. Nucleic Acids Res 23, 3231-3238.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 3231-3238
-
-
Ekland, E.H.1
Bartel, D.P.2
-
41
-
-
0029832218
-
RNA-catalysed RNA polymerization using nucleoside triphosphates
-
Ekland, E.H., Bartel, D.P. (1996). RNA-catalysed RNA polymerization using nucleoside triphosphates. Nature 382, 373-376.
-
(1996)
Nature
, vol.382
, pp. 373-376
-
-
Ekland, E.H.1
Bartel, D.P.2
-
42
-
-
0029147392
-
Structurally complex and highly active RNA ligases derive from random RNA sequences
-
Ekland, E.H., Szostak, J.W., and Bartel, D.P. (1995). Structurally complex and highly active RNA ligases derive from random RNA sequences. Science 269, 364-370.
-
(1995)
Science
, vol.269
, pp. 364-370
-
-
Ekland, E.H.1
Szostak, J.W.2
Bartel, D.P.3
-
43
-
-
0033215167
-
Small nucleolar RNAs
-
Eliceiri, G.L. (1999). Small nucleolar RNAs. Cell Mol Life Sci 56, 22-31.
-
(1999)
Cell Mol Life Sci
, vol.56
, pp. 22-31
-
-
Eliceiri, G.L.1
-
44
-
-
0025074907
-
In vitro selection of RNA molecules that bind specific ligands
-
Ellington, A.D., Szostak, J.W. (1990). In vitro selection of RNA molecules that bind specific ligands. Nature 346, 818-822.
-
(1990)
Nature
, vol.346
, pp. 818-822
-
-
Ellington, A.D.1
Szostak, J.W.2
-
45
-
-
0026599465
-
Selection in vitro of single-stranded DNA molecules that fold into specific ligand binding structures
-
Ellington, A.D., Szostak, J.W. (1992). Selection in vitro of single-stranded DNA molecules that fold into specific ligand binding structures. Nature 355,850-852.
-
(1992)
Nature
, vol.355
, pp. 850-852
-
-
Ellington, A.D.1
Szostak, J.W.2
-
46
-
-
0344326234
-
Chemical etiology of nucleic acid structure
-
Eschenmoser, A. (1999). Chemical etiology of nucleic acid structure. Science 284, 2118-2124.
-
(1999)
Science
, vol.284
, pp. 2118-2124
-
-
Eschenmoser, A.1
-
47
-
-
1542579763
-
The TNA-family of nucleic acid systems: properties and prospects
-
Eschenmoser, A. (2004). The TNA-family of nucleic acid systems: properties and prospects. Orig Life Evol Biosph 34, 277-306.
-
(2004)
Orig Life Evol Biosph
, vol.34
, pp. 277-306
-
-
Eschenmoser, A.1
-
48
-
-
0042430533
-
Unnatural RNA display libraries
-
Frankel, A., Li S., Starck, S.R., Roberts, R.W. (2003). Unnatural RNA display libraries. Curr Opin Struct Biol 13, 506-512.
-
(2003)
Curr Opin Struct Biol
, vol.13
, pp. 506-512
-
-
Frankel, A.1
Li, S.2
Starck, S.R.3
Roberts, R.W.4
-
49
-
-
0019128225
-
RNase P of Bacillus subtilis has a RNA component
-
Gardiner, K., Pace, N.R. (1980). RNase P of Bacillus subtilis has a RNA component. J Biol Chem 255, 7507-7509.
-
(1980)
J Biol Chem
, vol.255
, pp. 7507-7509
-
-
Gardiner, K.1
Pace, N.R.2
-
50
-
-
4644350506
-
DNAtemplated organic synthesis and selection of a library of macrocycles
-
Gartner, Z.J., Tse, B.N., Grubina, R., Doyon, J.B., Snyder, T.M., Liu, D.R. (2004). DNAtemplated organic synthesis and selection of a library of macrocycles. Science 305, 1601-1605.
-
(2004)
Science
, vol.305
, pp. 1601-1605
-
-
Gartner, Z.J.1
Tse, B.N.2
Grubina, R.3
Doyon, J.B.4
Snyder, T.M.5
Liu, D.R.6
-
51
-
-
0347482479
-
Nucleobase pairing in expanded Watson-Crick-like genetic information systems
-
Geyer, C.R., Battersby, T.R., Benner, S.A. (2003). Nucleobase pairing in expanded Watson-Crick-like genetic information systems. Structure (Camb) 11, 1485-1498.
-
(2003)
Structure (Camb)
, vol.11
, pp. 1485-1498
-
-
Geyer, C.R.1
Battersby, T.R.2
Benner, S.A.3
-
52
-
-
0035836707
-
Directed evolution of polymerase function by compartmentalized self-replication
-
Ghadessy, F.J., Ong, J.L., Holliger, P. (2001). Directed evolution of polymerase function by compartmentalized self-replication. Proc Natl Acad Sci USA 98, 4552-4557.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 4552-4557
-
-
Ghadessy, F.J.1
Ong, J.L.2
Holliger, P.3
-
53
-
-
2542525398
-
Generic expansion of the substrate spectrum of a DNA polymerase by directed evolution
-
Ghadessy, F.J., Ramsay, N., Boudsocq, F., Loakes, D., Brown, A., Iwai, S., Vaisman, A., Woodgate, R., Holliger, P. (2004). Generic expansion of the substrate spectrum of a DNA polymerase by directed evolution. Nat Biotechnol 22, 755-759.
-
(2004)
Nat Biotechnol
, vol.22
, pp. 755-759
-
-
Ghadessy, F.J.1
Ramsay, N.2
Boudsocq, F.3
Loakes, D.4
Brown, A.5
Iwai, S.6
Vaisman, A.7
Woodgate, R.8
Holliger, P.9
-
54
-
-
36849148382
-
The RNA World
-
Gilbert, W. (1986). The RNA World. Nature 319, 618.
-
(1986)
Nature
, vol.319
, pp. 618
-
-
Gilbert, W.1
-
55
-
-
0037172779
-
Metal ion requirements for structure and catalysis of an RNA ligase ribozyme
-
Glasner, M.E., Bergman, N.H., Bartel, D.P. (2002). Metal ion requirements for structure and catalysis of an RNA ligase ribozyme. Biochemistry 41, 8103-8112.
-
(2002)
Biochemistry
, vol.41
, pp. 8103-8112
-
-
Glasner, M.E.1
Bergman, N.H.2
Bartel, D.P.3
-
56
-
-
33746167205
-
On genetic information and genetic coding
-
In: The Scope of Logic, Methodology, and the Philosophy of Science, P. Gardenfors, J. Wolenski, K. Kajania-Placek, eds. Dordrecht: Kluwer
-
Godfrey-Smith, P. (2002). On genetic information and genetic coding. In: The Scope of Logic, Methodology, and the Philosophy of Science, Vol. II. P. Gardenfors, J. Wolenski, K. Kajania-Placek, eds. Dordrecht: Kluwer, pp. 387-400.
-
(2002)
, vol.II
, pp. 387-400
-
-
Godfrey-Smith, P.1
-
57
-
-
0025084575
-
In vitro genetic analysis of the Tetrahymena self-splicing intron
-
Green, R., Ellington, A.D., Szostak, J.W. (1990). In vitro genetic analysis of the Tetrahymena self-splicing intron. Nature 347, 406-408.
-
(1990)
Nature
, vol.347
, pp. 406-408
-
-
Green, R.1
Ellington, A.D.2
Szostak, J.W.3
-
58
-
-
0033908031
-
Man-made enzymes-from design to in vitro compartmentalisation
-
Griffiths, A.D., Tawfik, D.S. (2000). Man-made enzymes-from design to in vitro compartmentalisation. Curr Opin Biotechnol 11, 338-353.
-
(2000)
Curr Opin Biotechnol
, vol.11
, pp. 338-353
-
-
Griffiths, A.D.1
Tawfik, D.S.2
-
59
-
-
0037413687
-
Directed evolution of an extremely fast phosphotriesterase by in vitro compartmentalization
-
Griffiths, A.D., Tawfik, D.S. (2003). Directed evolution of an extremely fast phosphotriesterase by in vitro compartmentalization. EMBO J 22, 24-35.
-
(2003)
EMBO J
, vol.22
, pp. 24-35
-
-
Griffiths, A.D.1
Tawfik, D.S.2
-
60
-
-
0021013526
-
The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme
-
Guerrier-Takada, C., Gardiner, K., Marsh, T., Pace, N., Altman, S. (1983). The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme. Cell 35, 849-857.
-
(1983)
Cell
, vol.35
, pp. 849-857
-
-
Guerrier-Takada, C.1
Gardiner, K.2
Marsh, T.3
Pace, N.4
Altman, S.5
-
61
-
-
19344373204
-
DNA display II. Genetic manipulation of combinatorial chemistry libraries for small-molecule evolution
-
Halpin, D.R., Harbury, P.B. (2004). DNA display II. Genetic manipulation of combinatorial chemistry libraries for small-molecule evolution. PLoS Biol 2, E174.
-
(2004)
PLoS Biol
, vol.2
-
-
Halpin, D.R.1
Harbury, P.B.2
-
62
-
-
19344370973
-
DNA display III. Solid-phase organic synthesis on unprotected DNA
-
Halpin, D.R., Lee, J.A., Wrenn, S.J., Harbury, P.B. (2004). DNA display III. Solid-phase organic synthesis on unprotected DNA. PLoS Biol 2, E175.
-
(2004)
PLoS Biol
, vol.2
-
-
Halpin, D.R.1
Lee, J.A.2
Wrenn, S.J.3
Harbury, P.B.4
-
63
-
-
0033930772
-
Replicability and recurrence in the experimental evolution of a group I ribozyme
-
Hanczyc, M. M., Dorit, R. L. (2000). Replicability and recurrence in the experimental evolution of a group I ribozyme. Mol Biol Evol 17, 1050-1060.
-
(2000)
Mol Biol Evol
, vol.17
, pp. 1050-1060
-
-
Hanczyc, M.M.1
Dorit, R.L.2
-
64
-
-
8844249335
-
Replicating vesicles as models of primitive cell growth and division
-
Hanczyc, M.M., Szostak, J.W. (2004). Replicating vesicles as models of primitive cell growth and division. Curr Opin Chem Biol 8, 660-664.
-
(2004)
Curr Opin Chem Biol
, vol.8
, pp. 660-664
-
-
Hanczyc, M.M.1
Szostak, J.W.2
-
65
-
-
0142147270
-
Experimental models of primitive cellular compartments: encapsulation, growth, and division
-
Hanczyc, M.M., Fujikawa, S.M., Szostak, J.W. (2003). Experimental models of primitive cellular compartments: encapsulation, growth, and division. Science 302, 618-622.
-
(2003)
Science
, vol.302
, pp. 618-622
-
-
Hanczyc, M.M.1
Fujikawa, S.M.2
Szostak, J.W.3
-
66
-
-
0041832289
-
Evolutionary landscapes for the acquisition of new ligand recognition by RNA aptamers
-
Held, D.M., Greathouse, S.T., Agrawal, A., Burke, D.H. (2003). Evolutionary landscapes for the acquisition of new ligand recognition by RNA aptamers. J Mol Evol 57, 299-308.
-
(2003)
J Mol Evol
, vol.57
, pp. 299-308
-
-
Held, D.M.1
Greathouse, S.T.2
Agrawal, A.3
Burke, D.H.4
-
67
-
-
0034603154
-
Adaptive recognition by nucleic acid aptamers
-
Hermann, T., Patel, D.J. (2000). Adaptive recognition by nucleic acid aptamers. Science 287, 820-825.
-
(2000)
Science
, vol.287
, pp. 820-825
-
-
Hermann, T.1
Patel, D.J.2
-
68
-
-
0037439599
-
Simultaneous detection of diverse analytes with an aptazyme ligase array
-
Hesselberth, J.R., Robertson, M.P., Knudsen, S.M., Ellington, A.D. (2003). Simultaneous detection of diverse analytes with an aptazyme ligase array. Anal Biochem 312, 106-112.
-
(2003)
Anal Biochem
, vol.312
, pp. 106-112
-
-
Hesselberth, J.R.1
Robertson, M.P.2
Knudsen, S.M.3
Ellington, A.D.4
-
69
-
-
0344874269
-
Evolution of aptamers with a new specificity and new secondary structures from an ATP aptamer
-
Huang, Z., Szostak, J.W. (2003). Evolution of aptamers with a new specificity and new secondary structures from an ATP aptamer. RNA 9, 1456-1463.
-
(2003)
RNA
, vol.9
, pp. 1456-1463
-
-
Huang, Z.1
Szostak, J.W.2
-
70
-
-
0028965943
-
A DNA aptamer that binds adenosine and ATP
-
Huizenga, D.E., Szostak, J.W. (1995). A DNA aptamer that binds adenosine and ATP. Biochemistry 34, 656-665.
-
(1995)
Biochemistry
, vol.34
, pp. 656-665
-
-
Huizenga, D.E.1
Szostak, J.W.2
-
71
-
-
14844327763
-
An in vitro selection system for TNA
-
Ichida, J.K., Zou, K., Horhota, A., Yu, B., McLaughlin, L.W., Szostak, J.W. (2005). An in vitro selection system for TNA. J Am Chem Soc 127, 2802-2803.
-
(2005)
J Am Chem Soc
, vol.127
, pp. 2802-2803
-
-
Ichida, J.K.1
Zou, K.2
Horhota, A.3
Yu, B.4
McLaughlin, L.W.5
Szostak, J.W.6
-
72
-
-
0028224199
-
High-resolution molecular discrimination by RNA
-
Jenison, R. D., Gill, S. C., Pardi, A., Polisky, B. (1994). High-resolution molecular discrimination by RNA. Science 263, 1425-1429.
-
(1994)
Science
, vol.263
, pp. 1425-1429
-
-
Jenison, R.D.1
Gill, S.C.2
Pardi, A.3
Polisky, B.4
-
73
-
-
0029946537
-
Structural basis of RNA folding and recognition in an AMP-RNA aptamer complex
-
Jiang, F., Kumar, R.A, Jones, R.A., Patel, D.J. (1996). Structural basis of RNA folding and recognition in an AMP-RNA aptamer complex. Nature 382, 183-186.
-
(1996)
Nature
, vol.382
, pp. 183-186
-
-
Jiang, F.1
Kumar, R.A.2
Jones, R.A.3
Patel, D.J.4
-
74
-
-
0035906978
-
RNAcatalyzed RNA polymerization: accurate and general RNA-templated primer extension
-
Johnston, W.K., Unrau, P.J., Lawrence, M.S., Glasner, M.E., Bartel, D.P. (2001). RNAcatalyzed RNA polymerization: accurate and general RNA-templated primer extension. Science 292, 1319-1325.
-
(2001)
Science
, vol.292
, pp. 1319-1325
-
-
Johnston, W.K.1
Unrau, P.J.2
Lawrence, M.S.3
Glasner, M.E.4
Bartel, D.P.5
-
75
-
-
0024443885
-
Amplification, mutation, and selection of catalytic RNA
-
Joyce, G.F. (1989). Amplification, mutation, and selection of catalytic RNA. Gene 82, 83-87.
-
(1989)
Gene
, vol.82
, pp. 83-87
-
-
Joyce, G.F.1
-
76
-
-
0037062978
-
The antiquity of RNA-based evolution
-
Joyce, G.F. (2002). The antiquity of RNA-based evolution. Nature 418, 214-221.
-
(2002)
Nature
, vol.418
, pp. 214-221
-
-
Joyce, G.F.1
-
77
-
-
0021770666
-
Nonenzymatic template-directed synthesis on RNA random copolymers. Poly(C, U) templates
-
Joyce, G.F., Inoue, T., Orgel, L.E. (1984). Nonenzymatic template-directed synthesis on RNA random copolymers. Poly(C, U) templates. J Mol Biol 176, 279-306.
-
(1984)
J Mol Biol
, vol.176
, pp. 279-306
-
-
Joyce, G.F.1
Inoue, T.2
Orgel, L.E.3
-
78
-
-
0023372377
-
The case for an ancestral genetic system involving simple analogues of the nucleotides
-
Joyce, G.F., Schwartz, A.W., Miller, S., Orgel, L.E. (1987). The case for an ancestral genetic system involving simple analogues of the nucleotides. Proc Natl Acad Sci USA 84, 4398-4402.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 4398-4402
-
-
Joyce, G.F.1
Schwartz, A.W.2
Miller, S.3
Orgel, L.E.4
-
79
-
-
0348133608
-
RNA sensors: novel regulators of gene expression
-
Kaempfer, R. (2003). RNA sensors: novel regulators of gene expression. EMBO Rep 4, 1043-1047.
-
(2003)
EMBO Rep
, vol.4
, pp. 1043-1047
-
-
Kaempfer, R.1
-
80
-
-
4944255180
-
Reaction discovery enabled by DNA-templated synthesis and in vitro selection
-
Kanan, M.W., Rozenman, M.M., Sakurai, K., Snyder, T.M., Liu, D.R. (2004). Reaction discovery enabled by DNA-templated synthesis and in vitro selection. Nature 431, 545-549.
-
(2004)
Nature
, vol.431
, pp. 545-549
-
-
Kanan, M.W.1
Rozenman, M.M.2
Sakurai, K.3
Snyder, T.M.4
Liu, D.R.5
-
81
-
-
0022619420
-
Autocatalytic sets of proteins
-
Kauffman, S. (1986). Autocatalytic sets of proteins. J Theor Biol 119, 1-24.
-
(1986)
J Theor Biol
, vol.119
, pp. 1-24
-
-
Kauffman, S.1
-
82
-
-
0035810165
-
Functional proteins from a random-sequence library
-
Keefe, A.D., Szostak, J.W. (2001). Functional proteins from a random-sequence library. Nature 410, 715-718.
-
(2001)
Nature
, vol.410
, pp. 715-718
-
-
Keefe, A.D.1
Szostak, J.W.2
-
83
-
-
0037319334
-
Finding specific RNA motifs: function in a zeptomole world?
-
Knight, R., Yarus, M. (2003). Finding specific RNA motifs: function in a zeptomole world? RNA 9, 218-230.
-
(2003)
RNA
, vol.9
, pp. 218-230
-
-
Knight, R.1
Yarus, M.2
-
84
-
-
0032755647
-
Allosteric selection of ribozymes that respond to the second messengers cGMP and cAMP
-
Koizumi, M., Soukup, G.A., Kerr, J.N., Breaker, R.R. (1999). Allosteric selection of ribozymes that respond to the second messengers cGMP and cAMP. Nat Struct Biol 6, 1062-1071.
-
(1999)
Nat Struct Biol
, vol.6
, pp. 1062-1071
-
-
Koizumi, M.1
Soukup, G.A.2
Kerr, J.N.3
Breaker, R.R.4
-
85
-
-
0020417286
-
Selfsplicing RNA: autoexcision and autocyclization of the ribosomal RNA intervening sequence of Tetrahymena
-
Kruger, K., Grabowski, P.J., Zaug, A.J., Sands, J., Gottschling, D.E., Cech, T.R. (1982). Selfsplicing RNA: autoexcision and autocyclization of the ribosomal RNA intervening sequence of Tetrahymena. Cell 31, 147-157.
-
(1982)
Cell
, vol.31
, pp. 147-157
-
-
Kruger, K.1
Grabowski, P.J.2
Zaug, A.J.3
Sands, J.4
Gottschling, D.E.5
Cech, T.R.6
-
86
-
-
0029138009
-
RNA aptamers that bind flavin and nicotinamide redox cofactors
-
Lauhon, C.T., Szostak, J.W. (1995). RNA aptamers that bind flavin and nicotinamide redox cofactors. J Am Chem Soc 117, 1246-1257.
-
(1995)
J Am Chem Soc
, vol.117
, pp. 1246-1257
-
-
Lauhon, C.T.1
Szostak, J.W.2
-
87
-
-
0042347704
-
Processivity of ribozyme-catalyzed RNA polymerization
-
Lawrence, M.S., Bartel, D.P. (2003). Processivity of ribozyme-catalyzed RNA polymerization. Biochemistry 42, 8748-8755.
-
(2003)
Biochemistry
, vol.42
, pp. 8748-8755
-
-
Lawrence, M.S.1
Bartel, D.P.2
-
88
-
-
0027137780
-
Evolution in vitro: analysis of a lineage of ribozymes
-
Lehman, N., Joyce, G.F. (1993). Evolution in vitro: analysis of a lineage of ribozymes. Curr Biol 3, 723-34.
-
(1993)
Curr Biol
, vol.3
, pp. 723-734
-
-
Lehman, N.1
Joyce, G.F.2
-
89
-
-
0033936360
-
The genotypic landscape during in vitro evolution of a catalytic RNA: implications for phenotypic buffering
-
Lehman, N., Donne, M.D., West, M., Dewey, T.G. (2000). The genotypic landscape during in vitro evolution of a catalytic RNA: implications for phenotypic buffering. J Mol Evol 50, 481-490.
-
(2000)
J Mol Evol
, vol.50
, pp. 481-490
-
-
Lehman, N.1
Donne, M.D.2
West, M.3
Dewey, T.G.4
-
90
-
-
0030954291
-
Toward an efficient DNAzyme
-
Li, Y., Sen, D. (1997). Toward an efficient DNAzyme. Biochemistry 36, 5589-5599.
-
(1997)
Biochemistry
, vol.36
, pp. 5589-5599
-
-
Li, Y.1
Sen, D.2
-
91
-
-
0642306490
-
The origins of RNA catalysis in ribozymes
-
Lilley, D.M. (2003). The origins of RNA catalysis in ribozymes. Trends Biochem Sci 28, 495-501.
-
(2003)
Trends Biochem Sci
, vol.28
, pp. 495-501
-
-
Lilley, D.M.1
-
92
-
-
0242332191
-
A four-base paired genetic helix with expanded size
-
Liu, H., Gao, J., Lynch, S.R., Saito, Y.D., Maynard, L., Kool, E.T. (2003). A four-base paired genetic helix with expanded size. Science 302, 868-871.
-
(2003)
Science
, vol.302
, pp. 868-871
-
-
Liu, H.1
Gao, J.2
Lynch, S.R.3
Saito, Y.D.4
Maynard, L.5
Kool, E.T.6
-
93
-
-
0030072640
-
Chance and necessity in the selection of nucleic acid catalysts
-
Lorsch, J.R., Szostak, J.W. (1996). Chance and necessity in the selection of nucleic acid catalysts. Acc Chem Res 29, 103-110.
-
(1996)
Acc Chem Res
, vol.29
, pp. 103-110
-
-
Lorsch, J.R.1
Szostak, J.W.2
-
94
-
-
0036829840
-
Toward the engineering of minimal living cells
-
Luisi, P.L. (2002). Toward the engineering of minimal living cells. Anat Rec 268, 208-214.
-
(2002)
Anat Rec
, vol.268
, pp. 208-214
-
-
Luisi, P.L.1
-
95
-
-
0842334528
-
Adenine riboswitches and gene activation by disruption of a transcription terminator
-
Mandal, M., Breaker, R.R. (2004). Adenine riboswitches and gene activation by disruption of a transcription terminator. Nat Struct Mol Biol 11, 29-35.
-
(2004)
Nat Struct Mol Biol
, vol.11
, pp. 29-35
-
-
Mandal, M.1
Breaker, R.R.2
-
96
-
-
0037471691
-
On the origins of cells: a hypothesis for the evolutionary transitions from abiotic geochemistry to chemoautotrophic prokaryotes, and from prokaryotes to nucleated cells
-
Martin, W., Russell, M.J. (2003). On the origins of cells: a hypothesis for the evolutionary transitions from abiotic geochemistry to chemoautotrophic prokaryotes, and from prokaryotes to nucleated cells. Philos Trans R Soc Lond B Biol Sci 358, 59-83.
-
(2003)
Philos Trans R Soc Lond B Biol Sci
, vol.358
, pp. 59-83
-
-
Martin, W.1
Russell, M.J.2
-
97
-
-
0014935646
-
Natural selection and the concept of a protein space
-
Maynard Smith, J. (1970). Natural selection and the concept of a protein space. Nature 225, 563-564.
-
(1970)
Nature
, vol.225
, pp. 563-564
-
-
Maynard Smith, J.1
-
98
-
-
0033083733
-
It's a noisy business! Genetic regulation at the nanomolar scale
-
McAdams, H.H., Arkin, A. (1999). It's a noisy business! Genetic regulation at the nanomolar scale. Trends Genet 15, 65-69.
-
(1999)
Trends Genet
, vol.15
, pp. 65-69
-
-
McAdams, H.H.1
Arkin, A.2
-
99
-
-
19344373638
-
What is life-and how do we search for it in other worlds?
-
McKay, C.P. (2004). What is life-and how do we search for it in other worlds? PLoS Biol 2, e302.
-
(2004)
PLoS Biol
, vol.2
-
-
McKay, C.P.1
-
100
-
-
0002502220
-
Before RNA and after: Geophysical and geochemical constraints on molecular evolution
-
In: The RNA World, 2nd edn, Gesteland, R.F., Cech, T.R., Atkins, J.F., eds. New York: Cold Spring Harbor Press
-
Mojzsis, S.J., Krishnamurthy, R., Arrhenius, G. (1999). Before RNA and after: Geophysical and geochemical constraints on molecular evolution. In: The RNA World, 2nd edn, Gesteland, R.F., Cech, T.R., Atkins, J.F., eds. New York: Cold Spring Harbor Press, pp. 1-47.
-
(1999)
, pp. 1-47
-
-
Mojzsis, S.J.1
Krishnamurthy, R.2
Arrhenius, G.3
-
101
-
-
0041427845
-
Liposome-entrapped polymerases as models for microscale/nanoscale bioreactors
-
Monnard, P.A. (2003). Liposome-entrapped polymerases as models for microscale/nanoscale bioreactors. J Membr Biol 191, 87-97.
-
(2003)
J Membr Biol
, vol.191
, pp. 87-97
-
-
Monnard, P.A.1
-
102
-
-
0036829555
-
Membrane self-assembly processes: Steps toward the first cellular life
-
Monnard, P.A., Deamer, D.W. (2002). Membrane self-assembly processes: Steps toward the first cellular life. Anat Rec 268, 196-207.
-
(2002)
Anat Rec
, vol.268
, pp. 196-207
-
-
Monnard, P.A.1
Deamer, D.W.2
-
103
-
-
0037465559
-
Factors that contribute to efficient catalytic activity of a small Ca2+-dependent deoxyribozyme in relation to its RNA cleavage function
-
Okumoto, Y., Tanabe, Y., Sugimoto, N. (2003). Factors that contribute to efficient catalytic activity of a small Ca2+-dependent deoxyribozyme in relation to its RNA cleavage function. Biochemistry 42, 2158-2165.
-
(2003)
Biochemistry
, vol.42
, pp. 2158-2165
-
-
Okumoto, Y.1
Tanabe, Y.2
Sugimoto, N.3
-
104
-
-
0022845689
-
RNA catalysis and the origins of life
-
Orgel, L.E. (1986). RNA catalysis and the origins of life. J Theor Biol 123, 127-149.
-
(1986)
J Theor Biol
, vol.123
, pp. 127-149
-
-
Orgel, L.E.1
-
105
-
-
0346158948
-
Why does TNA cross-pair more strongly with RNA than with DNA? an answer from X-ray analysis
-
Pallan, P.S., Wilds, C.J., Wawrzak, Z., Krishnamurthy, R., Eschenmoser, A., Egli, M. (2003). Why does TNA cross-pair more strongly with RNA than with DNA? an answer from X-ray analysis. Angew Chem Int Ed Engl 42, 5893-5895.
-
(2003)
Angew Chem Int Ed Engl
, vol.42
, pp. 5893-5895
-
-
Pallan, P.S.1
Wilds, C.J.2
Wawrzak, Z.3
Krishnamurthy, R.4
Eschenmoser, A.5
Egli, M.6
-
106
-
-
0026755205
-
In vitro selection of RNAs that undergo autolytic cleavage with Pb2+
-
Pan, T., Uhlenbeck, O.C. (1992). In vitro selection of RNAs that undergo autolytic cleavage with Pb2+. Biochemistry 31, 3887-3895.
-
(1992)
Biochemistry
, vol.31
, pp. 3887-3895
-
-
Pan, T.1
Uhlenbeck, O.C.2
-
107
-
-
0036780107
-
Inaugural article: a self-replicating ligase ribozyme
-
Paul, N., Joyce, G.F. (2002). Inaugural article: a self-replicating ligase ribozyme. Proc Natl Acad Sci USA 99, 12733-12740.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 12733-12740
-
-
Paul, N.1
Joyce, G.F.2
-
108
-
-
0037180804
-
A ribozyme composed of only two different nucleotides
-
Reader, J.S., Joyce, G.F. (2002). A ribozyme composed of only two different nucleotides. Nature 420, 841-844.
-
(2002)
Nature
, vol.420
, pp. 841-844
-
-
Reader, J.S.1
Joyce, G.F.2
-
109
-
-
0034968504
-
Replication and mutation on neutral networks
-
Reidys, C., Forst, C. V., Schuster, P. (2001). Replication and mutation on neutral networks. Bull Math Biol 63, 57-94.
-
(2001)
Bull Math Biol
, vol.63
, pp. 57-94
-
-
Reidys, C.1
Forst, C.V.2
Schuster, P.3
-
110
-
-
0346726114
-
Borate minerals stabilize ribose
-
Ricardo, A., Carrigan, M.A., Olcott, A.N., Benner, S.A. (2004). Borate minerals stabilize ribose. Science 303, 196.
-
(2004)
Science
, vol.303
, pp. 196
-
-
Ricardo, A.1
Carrigan, M.A.2
Olcott, A.N.3
Benner, S.A.4
-
111
-
-
0141921620
-
Expanded divalent metal-ion tolerance of evolved ligase ribozymes
-
Riley, C.A., Lehman, N. (2003). Expanded divalent metal-ion tolerance of evolved ligase ribozymes. Biochimie 85, 683-689.
-
(2003)
Biochimie
, vol.85
, pp. 683-689
-
-
Riley, C.A.1
Lehman, N.2
-
112
-
-
0030817279
-
RNA-peptide fusions for the in vitro selection of peptides and proteins
-
Roberts, R.W., Szostak, J.W. (1997). RNA-peptide fusions for the in vitro selection of peptides and proteins. Proc Natl Acad Sci USA 94, 12297-12302.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 12297-12302
-
-
Roberts, R.W.1
Szostak, J.W.2
-
113
-
-
0025332385
-
Selection in vitro of an RNA enzyme that specifically cleaves single-stranded DNA
-
Robertson, D.L., Joyce, G.F. (1990). Selection in vitro of an RNA enzyme that specifically cleaves single-stranded DNA. Nature 344, 467-468.
-
(1990)
Nature
, vol.344
, pp. 467-468
-
-
Robertson, D.L.1
Joyce, G.F.2
-
115
-
-
0346992203
-
In vitro selection of ribozymes dependent on peptides for activity
-
Robertson, M.P., Knudsen, S.M., Ellington, A.D. (2004). In vitro selection of ribozymes dependent on peptides for activity. RNA 10, 114-127.
-
(2004)
RNA
, vol.10
, pp. 114-127
-
-
Robertson, M.P.1
Knudsen, S.M.2
Ellington, A.D.3
-
116
-
-
0033581938
-
A ribozyme that lacks cytidine
-
Rogers, J., Joyce, G.F. (1999). A ribozyme that lacks cytidine. Nature 402, 323-325.
-
(1999)
Nature
, vol.402
, pp. 323-325
-
-
Rogers, J.1
Joyce, G.F.2
-
117
-
-
0242415199
-
Efficient and Sequence-Specific DNA-Templated Polymerization of Peptide Nucleic Acid Aldehydes
-
Rosenbaum, D.M., and Liu, D.R. (2003). Efficient and Sequence-Specific DNA-Templated Polymerization of Peptide Nucleic Acid Aldehydes. J Am Chem Soc 125, 13924-13925.
-
(2003)
J Am Chem Soc
, vol.125
, pp. 13924-13925
-
-
Rosenbaum, D.M.1
Liu, D.R.2
-
118
-
-
0032568656
-
An amino acid as a cofactor for a catalytic polynucleotide
-
Roth, A., Breaker, R.R. (1998). An amino acid as a cofactor for a catalytic polynucleotide. Proc Natl Acad Sci USA 95, 6027-6031.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6027-6031
-
-
Roth, A.1
Breaker, R.R.2
-
119
-
-
1642308960
-
A universal definition of life: autonomy and open-ended evolution
-
Ruiz-Mirazo, K., Pereto, J., Moreno, A. (2004). A universal definition of life: autonomy and open-ended evolution. Orig Life Evol Biosph 34, 323-346.
-
(2004)
Orig Life Evol Biosph
, vol.34
, pp. 323-346
-
-
Ruiz-Mirazo, K.1
Pereto, J.2
Moreno, A.3
-
120
-
-
0031259915
-
Accessing rare activities from random RNA sequences: the importance of the length of molecules in the starting pool
-
Sabeti, P.C., Unrau, P.J., Bartel, D.P. (1997). Accessing rare activities from random RNA sequences: the importance of the length of molecules in the starting pool. Chem Biol 4, 767-774.
-
(1997)
Chem Biol
, vol.4
, pp. 767-774
-
-
Sabeti, P.C.1
Unrau, P.J.2
Bartel, D.P.3
-
121
-
-
0014827737
-
In vitro selection of bacteriophage Q-beta ribonucleic acid variants resistant to ethidium bromide
-
Saffhill, R., Schneider-Bernloehr, H., Orgel, L.E., Spiegelman, S. (1970). In vitro selection of bacteriophage Q-beta ribonucleic acid variants resistant to ethidium bromide. J Mol Biol 51, 531-539.
-
(1970)
J Mol Biol
, vol.51
, pp. 531-539
-
-
Saffhill, R.1
Schneider-Bernloehr, H.2
Orgel, L.E.3
Spiegelman, S.4
-
122
-
-
0035498871
-
In vitro evolution suggests multiple origins for the hammerhead ribozyme
-
Salehi-Ashtiani, K., Szostak, J.W. (2001). In vitro evolution suggests multiple origins for the hammerhead ribozyme. Nature 414, 82-84.
-
(2001)
Nature
, vol.414
, pp. 82-84
-
-
Salehi-Ashtiani, K.1
Szostak, J.W.2
-
123
-
-
0027180473
-
An RNA motif that binds ATP
-
Sassanfar, M., Szostak, J.W. (1993). An RNA motif that binds ATP. Nature 364, 550-553.
-
(1993)
Nature
, vol.364
, pp. 550-553
-
-
Sassanfar, M.1
Szostak, J.W.2
-
124
-
-
3142758746
-
A small aptamer with strong and specific recognition of the triphosphate of ATP
-
Sazani, P.L., Larralde, R., Szostak, J.W. (2004). A small aptamer with strong and specific recognition of the triphosphate of ATP. J Am Chem Soc 126, 8370.
-
(2004)
J Am Chem Soc
, vol.126
, pp. 8370
-
-
Sazani, P.L.1
Larralde, R.2
Szostak, J.W.3
-
125
-
-
0022228967
-
Periodic perturbations of chemical oscillators: experiments
-
Schneider, F.W. (1985). Periodic perturbations of chemical oscillators: experiments. Annu Rev Phys Chem 36, 347-378.
-
(1985)
Annu Rev Phys Chem
, vol.36
, pp. 347-378
-
-
Schneider, F.W.1
-
126
-
-
0023042012
-
Information content of binding sites on nucleotide sequences
-
Schneider, T. D., Stormo, G. D., Gold, L., and Ehrenfeucht, A. (1986). Information content of binding sites on nucleotide sequences. J Mol Biol 188, 415-431.
-
(1986)
J Mol Biol
, vol.188
, pp. 415-431
-
-
Schneider, T.D.1
Stormo, G.D.2
Gold, L.3
Ehrenfeucht, A.4
-
127
-
-
0034680801
-
Chemical etiology of nucleic acid structure: the alpha-threofuranosyl-(3'p2') oligonucleotide system
-
Schoning, K., Scholz, P., Guntha, S., Wu, X., Krishnamurthy, R., Eschenmoser, A. (2000). Chemical etiology of nucleic acid structure: the alpha-threofuranosyl-(3'p2') oligonucleotide system. Science 290, 1347-1351.
-
(2000)
Science
, vol.290
, pp. 1347-1351
-
-
Schoning, K.1
Scholz, P.2
Guntha, S.3
Wu, X.4
Krishnamurthy, R.5
Eschenmoser, A.6
-
128
-
-
0034698298
-
One sequence, two ribozymes: implications for the emergence of new ribozyme folds
-
Schultes, E.A., Bartel, D.P. (2000). One sequence, two ribozymes: implications for the emergence of new ribozyme folds. Science 289, 448-452.
-
(2000)
Science
, vol.289
, pp. 448-452
-
-
Schultes, E.A.1
Bartel, D.P.2
-
129
-
-
0033102314
-
A small catalytic RNA motif with Diels-Alderase activity
-
Seelig, B., Jaschke, A. (1999). A small catalytic RNA motif with Diels-Alderase activity. Chem Biol 6, 167-76.
-
(1999)
Chem Biol
, vol.6
, pp. 167-176
-
-
Seelig, B.1
Jaschke, A.2
-
130
-
-
0035070585
-
Immobilized RNA switches for the analysis of complex chemical and biological mixtures
-
Seetharaman, S., Zivarts, M., Sudarsan, N., Breaker, R.R. (2001). Immobilized RNA switches for the analysis of complex chemical and biological mixtures. Nat Biotechnol 19, 336-341.
-
(2001)
Nat Biotechnol
, vol.19
, pp. 336-341
-
-
Seetharaman, S.1
Zivarts, M.2
Sudarsan, N.3
Breaker, R.R.4
-
131
-
-
18744362702
-
Microbead display by in vitro compartmentalisation: selection for binding using flow cytometry
-
Sepp, A., Tawfik, D.S., Griffiths, A.D. (2002). Microbead display by in vitro compartmentalisation: selection for binding using flow cytometry. FEBS Lett 532, 455-458.
-
(2002)
FEBS Lett
, vol.532
, pp. 455-458
-
-
Sepp, A.1
Tawfik, D.S.2
Griffiths, A.D.3
-
132
-
-
1842618467
-
Sequence-specific cleavage of RNA in the absence of divalent metal ions by a DNAzyme incorporating imidazolyl and amino functionalities
-
Sidorov, A.V., Grasby, J.A., Williams, DM. (2004). Sequence-specific cleavage of RNA in the absence of divalent metal ions by a DNAzyme incorporating imidazolyl and amino functionalities. Nucleic Acids Res 32, 1591-1601.
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 1591-1601
-
-
Sidorov, A.V.1
Grasby, J.A.2
Williams, D.M.3
-
133
-
-
6344219578
-
Deoxyribozymes: DNA catalysts for bioorganic chemistry
-
Silverman, S.K. (2004). Deoxyribozymes: DNA catalysts for bioorganic chemistry. Org Biomol Chem 2, 2701-2706.
-
(2004)
Org Biomol Chem
, vol.2
, pp. 2701-2706
-
-
Silverman, S.K.1
-
134
-
-
0036830435
-
Molecular indicators (biomarkers) of past life
-
Simoneit, B.R. (2002). Molecular indicators (biomarkers) of past life. Anat Rec 268, 186-195.
-
(2002)
Anat Rec
, vol.268
, pp. 186-195
-
-
Simoneit, B.R.1
-
135
-
-
0347364647
-
Generating a synthetic genome by whole genome assembly: X174 bacteriophage from synthetic oligonucleotides
-
Smith, H.O., Hutchison, C.A., Pfannkoch, C., Venter, C.J. (2003). Generating a synthetic genome by whole genome assembly: X174 bacteriophage from synthetic oligonucleotides. Proc Natl Acad Sci USA 100, 15440-15445.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 15440-15445
-
-
Smith, H.O.1
Hutchison, C.A.2
Pfannkoch, C.3
Venter, C.J.4
-
136
-
-
0042658199
-
RNA, the first macromolecular catalyst: the ribosome is a ribozyme
-
Steitz, T.A., Moore, P.B. (2003). RNA, the first macromolecular catalyst: the ribosome is a ribozyme. Trends Biochem Sci 28, 411-418.
-
(2003)
Trends Biochem Sci
, vol.28
, pp. 411-418
-
-
Steitz, T.A.1
Moore, P.B.2
-
137
-
-
0028050350
-
Rapid evolution of a protein in vitro by DNA shuffling
-
Stemmer, W.P. (1994). Rapid evolution of a protein in vitro by DNA shuffling. Nature 370, 389-391.
-
(1994)
Nature
, vol.370
, pp. 389-391
-
-
Stemmer, W.P.1
-
138
-
-
0034525463
-
Ribonucleotide reductases: the link between an RNA and a DNA world?
-
Stubbe, J. (2000). Ribonucleotide reductases: the link between an RNA and a DNA world? Curr Opin Struct Biol 10, 731-736.
-
(2000)
Curr Opin Struct Biol
, vol.10
, pp. 731-736
-
-
Stubbe, J.1
-
139
-
-
0041523501
-
Structure and activity of ribozymes
-
In: Redesigning the Molecules of Life. S.A. Benner, ed. Heidelberg: Springer-Verlag
-
Szostak, J.W. (1988). Structure and activity of ribozymes. In: Redesigning the Molecules of Life. S.A. Benner, ed. Heidelberg: Springer-Verlag, pp. 87-114.
-
(1988)
, pp. 87-114
-
-
Szostak, J.W.1
-
140
-
-
0037665961
-
Functional information: molecular messages
-
Szostak, J.W. (2003). Functional information: molecular messages. Nature 423, 689.
-
(2003)
Nature
, vol.423
, pp. 689
-
-
Szostak, J.W.1
-
141
-
-
0035905809
-
Synthesizing life
-
Szostak, J.W., Bartel, D.P., Luisi, L. (2001). Synthesizing life. Nature 409, 387-390.
-
(2001)
Nature
, vol.409
, pp. 387-390
-
-
Szostak, J.W.1
Bartel, D.P.2
Luisi, L.3
-
142
-
-
0031854986
-
Man-made cell-like compartments for molecular evolution
-
Tawfik, D.S., Griffiths, A.D. (1998). Man-made cell-like compartments for molecular evolution. Nat Biotechnol 16, 652-656.
-
(1998)
Nat Biotechnol
, vol.16
, pp. 652-656
-
-
Tawfik, D.S.1
Griffiths, A.D.2
-
143
-
-
0642367619
-
Group I aptazymes as genetic regulatory switches
-
Thompson, K.M., Syrett, H.A., Knudsen, S.M., Ellington, A.D. (2002). Group I aptazymes as genetic regulatory switches. BMC Biotechnol 2, 21.
-
(2002)
BMC Biotechnol
, vol.2
, pp. 21
-
-
Thompson, K.M.1
Syrett, H.A.2
Knudsen, S.M.3
Ellington, A.D.4
-
144
-
-
1942456902
-
Reduction of an aldehyde by a NADH/Zn2+-dependent redox active ribozyme
-
Tsukiji, S., Pattnaik, S.B., Suga, H. (2004). Reduction of an aldehyde by a NADH/Zn2+-dependent redox active ribozyme. J Am Chem Soc 126, 5044-5045.
-
(2004)
J Am Chem Soc
, vol.126
, pp. 5044-5045
-
-
Tsukiji, S.1
Pattnaik, S.B.2
Suga, H.3
-
145
-
-
0025194307
-
Systematic evolution of ligands by exponential enrichment
-
Tuerk, C., Gold, L. (1990). Systematic evolution of ligands by exponential enrichment. Science 249, 505-510.
-
(1990)
Science
, vol.249
, pp. 505-510
-
-
Tuerk, C.1
Gold, L.2
-
146
-
-
0032541654
-
RNA-catalysed nucleotide synthesis
-
Unrau, P.J., Bartel, D.P. (1998). RNA-catalysed nucleotide synthesis. Nature 395, 260-263.
-
(1998)
Nature
, vol.395
, pp. 260-263
-
-
Unrau, P.J.1
Bartel, D.P.2
-
147
-
-
84889362995
-
Factors that affect the outcome of in vitro selection
-
Harvard University doctoral thesis
-
Urbach, J.M. (2000). Factors that affect the outcome of in vitro selection. Harvard University doctoral thesis.
-
(2000)
-
-
Urbach, J.M.1
-
148
-
-
0042848694
-
A novel, modification-dependent ATP-binding aptamer selected from an RNA library incorporating a cationic functionality
-
Vaish, N.K., Larralde, R., Fraley, A.W., Szostak, J.W., McLaughlin, L.W. (2003). A novel, modification-dependent ATP-binding aptamer selected from an RNA library incorporating a cationic functionality. Biochemistry 42, 8842-8851.
-
(2003)
Biochemistry
, vol.42
, pp. 8842-8851
-
-
Vaish, N.K.1
Larralde, R.2
Fraley, A.W.3
Szostak, J.W.4
McLaughlin, L.W.5
-
149
-
-
0035823759
-
Proteinbased materials, toward a new level of structural control
-
van Hest, J.C., Tirrell, D.A. (2001). Proteinbased materials, toward a new level of structural control. Chem Commun (Camb) 19, 1897-1904.
-
(2001)
Chem Commun (Camb)
, vol.19
, pp. 1897-1904
-
-
Van Hest, J.C.1
Tirrell, D.A.2
-
150
-
-
0024390674
-
The design and catalytic properties of a simplified ribonuclease P RNA
-
Waugh, D.S., Green, C.J., Pace, N.R. (1989). The design and catalytic properties of a simplified ribonuclease P RNA. Science 244, 1569-1571.
-
(1989)
Science
, vol.244
, pp. 1569-1571
-
-
Waugh, D.S.1
Green, C.J.2
Pace, N.R.3
-
151
-
-
0032853242
-
In vitro selection of functional nucleic acids
-
Wilson, D.S., Szostak, J.W. (1999). In vitro selection of functional nucleic acids. Annu Rev Biochem 68, 611-647.
-
(1999)
Annu Rev Biochem
, vol.68
, pp. 611-647
-
-
Wilson, D.S.1
Szostak, J.W.2
-
152
-
-
0030901131
-
Continuous in vitro evolution of catalytic function
-
Wright, M.C., Joyce, G.F. (1997). Continuous in vitro evolution of catalytic function. Science 276, 614-617.
-
(1997)
Science
, vol.276
, pp. 614-617
-
-
Wright, M.C.1
Joyce, G.F.2
-
153
-
-
0029972909
-
Structural basis of ligand discrimination by two related RNA aptamers resolved by NMR spectroscopy
-
Yang, Y., Kochoyan, M., Burgstaller, P, Westhof, E., Famulok, M. (1996). Structural basis of ligand discrimination by two related RNA aptamers resolved by NMR spectroscopy. Science 272, 1343-1347.
-
(1996)
Science
, vol.272
, pp. 1343-1347
-
-
Yang, Y.1
Kochoyan, M.2
Burgstaller, P.3
Westhof, E.4
Famulok, M.5
-
154
-
-
0346555269
-
Optimization of specificity in a cellular protein interaction network by negative selection
-
Zarrinpar, A., Park, S-H., Lim, W.A. (2003). Optimization of specificity in a cellular protein interaction network by negative selection. Nature 426, 676-680.
-
(2003)
Nature
, vol.426
, pp. 676-680
-
-
Zarrinpar, A.1
Park, S.-H.2
Lim, W.A.3
-
155
-
-
0030754926
-
Optimization of DNA shuffling for high fidelity recombination
-
Zhao, H., Arnold, F.H. (1997). Optimization of DNA shuffling for high fidelity recombination. Nucleic Acids Res 25, 1307-1308.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 1307-1308
-
-
Zhao, H.1
Arnold, F.H.2
-
156
-
-
0036215509
-
Selection, design, and characterization of a new potentially therapeutic ribozyme
-
Zinnen, S.P., Domenico, K., Wilson, M., Dickinson, B.A., Beaudry, A., Mokler, V., Daniher, A.T., Burgin, A., Beigelman, L. (2002). Selection, design, and characterization of a new potentially therapeutic ribozyme. RNA 8, 214-228.
-
(2002)
RNA
, vol.8
, pp. 214-228
-
-
Zinnen, S.P.1
Domenico, K.2
Wilson, M.3
Dickinson, B.A.4
Beaudry, A.5
Mokler, V.6
Daniher, A.T.7
Burgin, A.8
Beigelman, L.9
|