Sequence-specific cleavage of RNA in the absence of divalent metal ions by a DNAzyme incorporating imidazolyl and amino functionalities

Nucleic Acids Research

Volumn 32, Issue 4, 2004, Pages 1591-1601

  Sidorov, Alexander V ^a   Grasby, Jane A ^a   Williams, David M ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

3 (AMINOPROPYNYL) 7 DEAZA DEOXYADENOSINE TRIPHOSPHATE; DEOXYADENOSINE TRIPHOSPHATE; DEOXYRIBOZYME; DEOXYURIDINE TRIPHOSPHATE DERIVATIVE; HISTIDINE DERIVATIVE; LYSINE DERIVATIVE; METAL ION; RIBONUCLEASE A; RNA; UNCLASSIFIED DRUG; DEOXYRIBONUCLEOTIDE; DIVALENT CATION; DRUG DERIVATIVE; FLUORESCEIN; FLUORESCENT DYE; HISTIDINE; LYSINE; METAL;

ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME MODIFICATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; HYDROLYSIS; IN VITRO STUDY; IONIC STRENGTH; MOLECULAR RECOGNITION; PH; PRIORITY JOURNAL; RNA DEGRADATION; RNA SEQUENCE; CHEMISTRY; CONFORMATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KINETICS; METABOLISM; NUCLEOTIDE SEQUENCE;

BASE SEQUENCE; CATIONS, DIVALENT; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYRIBONUCLEOTIDES; DNA, CATALYTIC; FLUORESCEIN; FLUORESCENT DYES; HISTIDINE; KINETICS; LYSINE; METALS; NUCLEIC ACID CONFORMATION; RNA; SUBSTRATE SPECIFICITY;

EID: 1842618467     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkh326     Document Type: Article

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