Selection, design, and characterization of a new potentially therapeutic ribozyme

RNA

Volumn 8, Issue 2, 2002, Pages 214-228

  Zinnen, Shawn P ^a   Domenico, Kristal ^a   Wilson, Mike ^a   Dickinson, Brent A ^a   Beaudry, Amber ^a   Mokler, Victor ^a   Daniher, Andrew T ^a   Burgin, Alex ^a   Beigelman, Leonid ^a  

^a Sirna Therapeutics Inc   (United States)

Author keywords

Catalysis; Divalent ions; Herzyme ; Nuclease stability; Ribozyme; RNA cleavage

Indexed keywords

ADENOSINE TRIPHOSPHATE DERIVATIVE; CALCIUM ION; CYTIDINE TRIPHOSPHATE; DNA; EXONUCLEASE; GUANOSINE TRIPHOSPHATE DERIVATIVE; HERZYME; MAGNESIUM ION; MESSENGER RNA; METAL ION; NUCLEASE; OLIGONUCLEOTIDE; PHOSPHODIESTERASE; RIBOZYME; RNA; URIDINE TRIPHOSPHATE; ZINZYME;

ARTICLE; CATALYSIS; CATALYST; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME SUBSTRATE; HALF LIFE TIME; PRIORITY JOURNAL; RNA CLEAVAGE; RNA SEQUENCE; RNA STRUCTURE;

BASE SEQUENCE; DRUG DESIGN; DRUG STABILITY; GENE LIBRARY; KINETICS; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; OLIGODEOXYRIBONUCLEOTIDES; RNA, CATALYTIC; TRANSCRIPTION, GENETIC;

EID: 0036215509     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1355838202014723     Document Type: Article

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