Advances in nanomedicines for malaria treatment

Advances in Colloid and Interface Science

Volumn 201-202, Issue , 2013, Pages 1-17

  Aditya, N P ^a   Vathsala, P G ^b   Vieira, V ^c   Murthy, R S R ^d   Souto, E B ^c  

^a Sejong University   (South Korea)

^b INDIAN INSTITUTE OF SCIENCE   (India)

^c UNIVERSIDADE FERNANDO PESSOA   (Portugal)

^d ISF COLLEGE OF PHARMACY   (India)

Author keywords

Colloidal carriers; Dendrimers; Lipids; Liposomes; Malaria; Microfluidics; Nanomedicine; Plasmodium; Polymers; Solid lipid nanoparticles; Toxicity

Indexed keywords

BIO-COMPATIBLE SYSTEMS; COLLOIDAL CARRIERS; INFECTIOUS DISEASE; MALARIA; PLASMODIUM; SOLID LIPID NANOPARTICLE (SLN); TARGET DELIVERY; TROPICAL COUNTRIES;

BIOCOMPATIBILITY; DENDRIMERS; DISEASES; DRUG DELIVERY; LIPIDS; LIPOSOMES; MEDICAL NANOTECHNOLOGY; MICROFLUIDICS; POLYMERS; TOXICITY;

MALARIA CONTROL;

ANTIMALARIAL AGENT; BIOMATERIAL; BUTYLCRESOL; DENDRIMER; DIHYDROARTEMISININ; DIPALMITOYLPHOSPHATIDYLCHOLINE; DISTEAROYLPHOSPHATIDYLCHOLINE; LIPID; LIPOSOME; MALARIA VACCINE; MEDIUM CHAIN TRIACYLGLYCEROL; NANOPARTICLE; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE; PHOSPHATIDYLGLYCEROL; POLYMER; POLYPROPYLENEIMINE; POVIDONE; SILVER NANOPARTICLE; SOLID LIPID NANOPARTICLE;

1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE; ABSORPTION, DISTRIBUTION, METABOLISM AND EXCRETION; ACT; ADME; AFM; AG NPS; ANIMAL; AREA UNDER THE CURVE; AREA UNDER THE PLASMA LEVEL-TIME CURVE; ARTEMISIN COMBINATION THERAPY; ATOMIC FORCE MICROSCOPY; CCRD; CENTRAL COMPOSITE ROTABLE DESIGN; CHEMISTRY; CHILD; CHOL; CHOLESTROL; CLINICAL TRIAL (TOPIC); COLLOID; COLLOIDAL CARRIERS; DEP; DHA; DIBENHENOYL PHOSPHATIDYLCHOLINE; DIFFERENCIAL SCANNING CALORIMETRY; DIMYRISTOYL PHOSPHATIDYLCHOLINE; DIMYRISTOYL PHOSPHATIDYLGLYCEROL; DIPALMITOYL PHOSPHATIDYLGLYCEROL; DISTEAROYL PHOSPHATIDYLGLYCEROL; DISTEAROYL PHOSPHOETHANOLAMINE; DL; DLS; DMPC; DMPG; DNDI; DOPC; DPPC; DPPG; DRUG DELIVERY SYSTEM; DRUG DEVELOPMENT; DRUG LOADING; DRUGS FOR NEGLETED DISEASES INITIATE; DSC; DSPC; DSPE; DSPG; DYNAMIC LIGHT SCATTERING; EE; EGG PHOSPHATIDYLCHOLINE; EGG PHOSPHATIDYLGLYCEROL; ELECTROPHORESIS; ENCAPSULATION EFFICIENCY; ENDPLATE CURRENT; EPG; ERYTHROCYTE; ERYTHROCYTE MEMBRANE; FACS; FEMALE; FFF; FIELD-FLOW-FRACTIONATION; FLUORESCENCE ACTIVATED CELL SORTING; FOOD VACUOLE MEMBRANE; FOURIER TRANSFORMED INFRARED SPECTROSCOPY; FTIR; FVM; GENE THERAPY; HCM; HOST RED CELL MEMBRANE; HPMC; HPΒCD; HUMAN; HYDROXYL PROPYL METHYL CELLULOSE; HYDROXYPROPYL-Β-CYCLODEXTRIN; ICT; IMMUNE CHROMATOGRAPHIC TESTS; INSTITUTE FOR ONE WORLD HEALTH; IOWH; LC; LEUKOCYTE; LOADING CAPACITY; MALARIA; MALE; MEDICINE FOR MALARIA VENTURE; METABOLISM; MICRO ANALYSIS SYSTEMS; MICROFLUIDICS; MITOCHONDRIAL MEMBRANE; MM; MMV; MOSQUITO; MULTIDRUG RESISTANCE; NANOMEDICINE; NANOSTRUCTURED LIPID CARRIERS; NEW PERMEATION PATHWAYS; NLC; NPP; NUCLEAR MAGNETIC RESONANCE; ODNS; OLIGODEOXYNUCLEOTIDES; PACA; PARASITE PLASMA MEMBRANE; PC; PCQD; PCS; PE; PG; PHOTON CORRELATION SPECTROSCOPY; PLASMODIUM; PLGA; POLY (D,L-LACTIDE-CO-GLYCOLIDE); POLYALKYLCYANOACRYLATES; POLYVINYL PYRROLIDON; POSITIVELY CHARGED QDOTS; PPI; PPM; PREGNANCY; RBCM; RESPONSE SURFACE METHOD; REVIEW; RSM; SCANNING ELECTRON MICROSCOPY; SELF-MICRO EMULSIFYING DRUG DELIVERY SYSTEMS; SLN; SMEDDS; TEM; TNF-Α; TOXICITY; TRANSMISSION ELECTRON MICROSCOPY; TUBOVESICULAR MEMBRANE; TUMOR NECROSIS FACTOR-Α; TVM; ΜTAS;

1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE; ABSORPTION, DISTRIBUTION, METABOLISM AND EXCRETION; ACT; ADME; AFM; AG NPS; AREA UNDER THE PLASMA LEVEL-TIME CURVE; ARTEMISIN COMBINATION THERAPY; ATOMIC FORCE MICROSCOPY; AUC; CCRD; CENTRAL COMPOSITE ROTABLE DESIGN; CHOL; CHOLESTROL; COLLOIDAL CARRIERS; DBPC; DENDRIMERS; DEP; DHA; DIBENHENOYL PHOSPHATIDYLCHOLINE; DIELECTROPHORESIS; DIFFERENCIAL SCANNING CALORIMETRY; DIHYDROARTEMISININ; DIMYRISTOYL PHOSPHATIDYLCHOLINE; DIMYRISTOYL PHOSPHATIDYLGLYCEROL; DIPALMITOYL PHOSPHATIDYLCHOLINE; DIPALMITOYL PHOSPHATIDYLGLYCEROL; DISTEAROYL PHOSPHATIDYLCHOLINE; DISTEAROYL PHOSPHATIDYLGLYCEROL; DISTEAROYL PHOSPHOETHANOLAMINE; DL; DLS; DMPC; DMPG; DNDI; DOPC; DPPC; DPPG; DRUG LOADING; DRUGS FOR NEGLETED DISEASES INITIATE; DSC; DSPC; DSPE; DSPG; DYNAMIC LIGHT SCATTERING; EE; EGG PHOSPHATIDYLCHOLINE; EGG PHOSPHATIDYLGLYCEROL; ENCAPSULATION EFFICIENCY; EPC; EPG; FACS; FFF; FIELD-FLOW-FRACTIONATION; FLUORESCENCE ACTIVATED CELL SORTING; FOOD VACUOLE MEMBRANE; FOURIER TRANSFORMED INFRARED SPECTROSCOPY; FTIR; FVM; HCM; HOST RED CELL MEMBRANE; HPMC; HPΒCD; HYDROXYL PROPYL METHYL CELLULOSE; HYDROXYPROPYL-Β-CYCLODEXTRIN; ICT; IMMUNE CHROMATOGRAPHIC TESTS; INSTITUTE FOR ONE WORLD HEALTH; IOWH; LC; LIPIDS; LIPOSOMES; LOADING CAPACITY; MALARIA; MCT; MEDICINE FOR MALARIA VENTURE; MEDIUM CHAIN TRIGLYCERIDE; MICRO ANALYSIS SYSTEMS; MICROFLUIDICS; MITOCHONDRIAL MEMBRANE; MM; MMV; NANOMEDICINE; NANOSTRUCTURED LIPID CARRIERS; NEW PERMEATION PATHWAYS; NLC; NMR; NPP; NUCLEAR MAGNETIC RESONANCE; ODNS; OLIGODEOXYNUCLEOTIDES; PACA; PARASITE PLASMA MEMBRANE; PC; PCQD; PCS; PE; PG; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE; PHOSPHATIDYLGLYCEROL; PHOTON CORRELATION SPECTROSCOPY; PLASMODIUM; PLGA; POLY (D,L-LACTIDE-CO-GLYCOLIDE); POLYALKYLCYANOACRYLATES; POLYMERS; POLYPROPYLENEIMINE; POLYVINYL PYRROLIDON; POSITIVELY CHARGED QDOTS; PPI; PPM; PVP; RBC; RBCM; RED BLOOD CELL; RED BLOOD CELL MEMBRANE; RESPONSE SURFACE METHODOLOGY; RSM; SCANNING ELECTRON MICROSCOPY; SELF-MICRO EMULSIFYING DRUG DELIVERY SYSTEMS; SEM; SILVER NANOPARTICLES; SLN; SMEDDS; SOLID LIPID NANOPARTICLES; TEM; TNF-Α; TOXICITY; TRANSMISSION ELECTRON MICROSCOPY; TUBOVESICULAR MEMBRANE; TUMOR NECROSIS FACTOR-Α; TVM; WBC; WHITE BLOOD CELL; ΜTAS;

ANIMALS; ANTIMALARIALS; BIOCOMPATIBLE MATERIALS; CHILD; CLINICAL TRIALS AS TOPIC; COLLOIDS; CULICIDAE; DENDRIMERS; DRUG DELIVERY SYSTEMS; DRUG DISCOVERY; DRUG RESISTANCE, MULTIPLE; FEMALE; GENETIC THERAPY; HUMANS; LIPIDS; LIPOSOMES; MALARIA; MALARIA VACCINES; MALE; NANOMEDICINE; NANOPARTICLES; PLASMODIUM; POLYMERS; PREGNANCY;

EID: 84888345927     PISSN: 00018686     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cis.2013.10.014     Document Type: Review

References (208)

1. B.M. Greenwood, K. Bojang, C.J. Whitty, and G.A. Targett Malaria Lancet 365 2005 1487 1498 (Pubitemid 40591695)
2. R.W. Snow, C.A. Guerra, A.M. Noor, H.Y. Myint, and S.I. Hay The global distribution of clinical episodes of Plasmodium falciparum malaria Nature 434 2005 214 217 (Pubitemid 40388051)
3. E.L. Korenromp, B.G. Williams, E. Gouws, C. Dye, and R.W. Snow Measurement of trends in childhood malaria mortality in Africa: an assessment of progress toward targets based on verbal autopsy Lancet Infect Dis 3 2003 349 358 (Pubitemid 36718014)
4. P. Druilhe, P. Daubersies, J. Patarapotikul, C. Gentil, L. Chene, and T. Chongsuphajaisiddhi A primary malarial infection is composed of a very wide range of genetically diverse but related parasites J Clin Invest 101 1998 2008 2016 (Pubitemid 28226121)
5. S.L. Croft, and P. Olliaro Leishmaniasis chemotherapy - challenges and opportunities Clin Microbiol Infect 17 2011 1478 1483
6. R. Pink, A. Hudson, M.A. Mouries, and M. Bendig Opportunities and challenges in antiparasitic drug discovery Nat Rev Drug Discov 4 2005 727 740 (Pubitemid 43090494)
7. V.C. Mosqueira, P.M. Loiseau, C. Bories, P. Legrand, J.P. Devissaguet, and G. Barratt Efficacy and pharmacokinetics of intravenous nanocapsule formulations of halofantrine in Plasmodium berghei-infected mice Antimicrob Agents Chemother 48 2004 1222 1228 (Pubitemid 38405476)
8. Z. Hawass, Y.Z. Gad, S. Ismail, R. Khairat, D. Fathalla, and N. Hasan Ancestry and pathology in King Tutankhamun's family JAMA 303 2010 638 647
9. R.L. Miller, S. Ikram, G.J. Armelagos, R. Walker, W.B. Harer, and C.J. Shiff Diagnosis of Plasmodium falciparum infections in mummies using the rapid manual ParaSight-F test Trans R Soc Trop Med Hyg 88 1994 31 32
10. J. de Zulueta Malaria and ecosystems: from prehistory to posteradication Parassitologia 36 1994 7 15
11. S. Jarcho Malaria and murder (Joseph Jones, 1878) Bull N Y Acad Med 44 1968 759 760
12. S. Jarcho Some observations on disease in prehistoric North America Bull Hist Med 38 1964 1 19
13. P.C. Garnham Comments on biology of human malaria Mil Med 131 1966 961 962 [Suppl.]
14. D. Bell, C. Wongsrichanalai, and J.W. Barnwell Ensuring quality and access for malaria diagnosis: how can it be achieved? Nat Rev Microbiol 4 2006 682 695
15. C.K. Murray, R.A. Gasser Jr., A.J. Magill, and R.S. Miller Update on rapid diagnostic testing for malaria Clin Microbiol Rev 21 2008 97 110 (Pubitemid 351160011)
16. J.S. Yeom, G. Jun, J.Y. Kim, W.J. Lee, E.H. Shin, and K.S. Chang Status of Plasmodium vivax malaria in the Republic of Korea, 2008-2009: decrease followed by resurgence Trans R Soc Trop Med Hyg 106 2012 429 436
17. D.S. Yamamoto, M. Sumitani, H. Nagumo, S. Yoshida, and H. Matsuoka Induction of antisporozoite antibodies by biting of transgenic Anopheles stephensi delivering malarial antigen via blood feeding Insect Mol Biol 21 2012 223 233
18. D.K. Mathias, J.L. Plieskatt, J.S. Armistead, J.M. Bethony, K.B. Abdul-Majid, and A. McMillan Expression, immunogenicity, histopathology, and potency of a mosquito-based malaria transmission-blocking recombinant vaccine Infect Immun 80 2012 1606 1614
19. S.K. Ghosh, S. Tiwari, K. Raghavendra, T.S. Sathyanarayan, and A.P. Dash Observations on sporozoite detection in naturally infected sibling species of the Anopheles culicifacies complex and variant of Anopheles stephensi in India J Biosci 33 2008 333 336
20. S.K. Ghosh, S.N. Tiwari, T.S. Sathyanarayan, T.R. Sampath, V.P. Sharma, and N. Nanda Larvivorous fish in wells target the malaria vector sibling species of the Anopheles culicifacies complex in villages in Karnataka, India Trans R Soc Trop Med Hyg 99 2005 101 105 (Pubitemid 40028790)
21. N.M. Douglas, N.M. Anstey, P.A. Buffet, J.R. Poespoprodjo, T.W. Yeo, and N.J. White The anaemia of Plasmodium vivax malaria Malar J 11 2012 135
22. R.N. Price, N.M. Douglas, N.M. Anstey, and L. von Seidlein Plasmodium vivax treatments: what are we looking for? Curr Opin Infect Dis 24 2011 578 585
23. J.R. Poespoprodjo, W. Fobia, E. Kenangalem, D.A. Lampah, A. Hasanuddin, and N. Warikar Vivax malaria: a major cause of morbidity in early infancy Clin Infect Dis 48 2009 1704 1712
24. I.A. McGregor Mechanisms of acquired immunity and epidemiological patterns of antibody responses in malaria in man Bull World Health Organ 50 1974 259 266
25. S.M. Muxel, A.P. Freitas do Rosario, C.A. Zago, S.I. Castillo-Mendez, L.R. Sardinha, and S.M. Rodriguez-Malaga The spleen CD4 + T cell response to blood-stage Plasmodium chabaudi malaria develops in two phases characterized by different properties PLoS One 6 2011 e22434
26. T.O. Diallo, F. Remoue, L. Gaayeb, A.M. Schacht, N. Charrier, and D. De Clerck Schistosomiasis coinfection in children influences acquired immune response against Plasmodium falciparum malaria antigens PLoS One 5 2010 e12764
27. M.O. Makobongo, G. Riding, H. Xu, C. Hirunpetcharat, D. Keough, and J. de Jersey The purine salvage enzyme hypoxanthine guanine xanthine phosphoribosyl transferase is a major target antigen for cell-mediated immunity to malaria Proc Natl Acad Sci U S A 100 2003 2628 2633 (Pubitemid 36297549)
28. L. Schofield, M.C. Hewitt, K. Evans, M.A. Siomos, and P.H. Seeberger Synthetic GPI as a candidate anti-toxic vaccine in a model of malaria Nature 418 2002 785 789
29. A. Molano, S.H. Park, Y.H. Chiu, S. Nosseir, A. Bendelac, and M. Tsuji Cutting edge: the IgG response to the circumsporozoite protein is MHC class II-dependent and CD1d-independent: exploring the role of GPIs in NK T cell activation and antimalarial responses J Immunol 164 2000 5005 5009 (Pubitemid 30305169)
30. C.F. Ockenhouse, P.F. Sun, D.E. Lanar, B.T. Wellde, B.T. Hall, and K. Kester Phase I/IIa safety, immunogenicity, and efficacy trial of NYVAC-Pf7, a pox-vectored, multiantigen, multistage vaccine candidate for Plasmodium falciparum malaria J Infect Dis 177 1998 1664 1673 (Pubitemid 28243593)
31. P.L. Alonso, J. Sacarlal, J.J. Aponte, A. Leach, E. Macete, and P. Aide Duration of protection with RTS, S/AS02A malaria vaccine in prevention of Plasmodium falciparum disease in Mozambican children: single-blind extended follow-up of a randomised controlled trial Lancet 366 2005 2012 2018 (Pubitemid 41773376)
32. P.L. Alonso, J. Sacarlal, J.J. Aponte, A. Leach, E. Macete, and J. Milman Efficacy of the RTS, S/AS02A vaccine against Plasmodium falciparum infection and disease in young African children: randomised controlled trial Lancet 364 2004 1411 1420 (Pubitemid 39370716)
33. F. Gay, S. Zougbede, N. N'Dilimabaka, A. Rebollo, D. Mazier, and A. Moreno Cerebral malaria: what is known and what is on research Rev Neurol (Paris) 168 2012 239 256
34. S. Mohanty, D.K. Patel, S.S. Pati, and S.K. Mishra Adjuvant therapy in cerebral malaria Indian J Med Res 124 2006 245 260 (Pubitemid 44734281)
35. S.J. Dunachie, M. Walther, J.M. Vuola, D.P. Webster, S.M. Keating, and T. Berthoud A clinical trial of prime-boost immunisation with the candidate malaria vaccines RTS, S/AS02A and MVA-CS Vaccine 24 2006 2850 2859
36. J. Schneider, J.A. Langermans, S.C. Gilbert, T.J. Blanchard, S. Twigg, and S. Naitza A prime-boost immunisation regimen using DNA followed by recombinant modified vaccinia virus Ankara induces strong cellular immune responses against the Plasmodium falciparum TRAP antigen in chimpanzees Vaccine 19 2001 4595 4602 (Pubitemid 32800740)
37. J. Schneider, S.C. Gilbert, C.M. Hannan, P. Degano, E. Prieur, and E.G. Sheu Induction of CD8 + T cells using heterologous prime-boost immunisation strategies Immunol Rev 170 1999 29 38 (Pubitemid 29490742)
38. J.M. Marshall, and C.E. Taylor Malaria control with transgenic mosquitoes PLoS Med 6 2009 e20
39. F. Catteruccia, H.C. Godfray, and A. Crisanti Impact of genetic manipulation on the fitness of Anopheles stephensi mosquitoes Science 299 2003 1225 1227 (Pubitemid 36237462)
40. A. Mohmmed, P.V. Dasaradhi, R.K. Bhatnagar, V.S. Chauhan, and P. Malhotra In vivo gene silencing in Plasmodium berghei - a mouse malaria model Biochem Biophys Res Commun 309 2003 506 511 (Pubitemid 37083280)
41. N.J. White, and M. Ho The pathophysiology of malaria Adv Parasitol 31 1992 83 173
42. P.A. Holding, J. Stevenson, N. Peshu, and K. Marsh Cognitive sequelae of severe malaria with impaired consciousness Trans R Soc Trop Med Hyg 93 1999 529 534 (Pubitemid 29495841)
43. J.A. Carter, V. Mung'ala-Odera, B.G. Neville, G. Murira, N. Mturi, and C. Musumba Persistent neurocognitive impairments associated with severe falciparum malaria in Kenyan children J Neurol Neurosurg Psychiatry 76 2005 476 481 (Pubitemid 40486569)
44. F.J. Breeveld, S.G. Vreden, and M.P. Grobusch History of malaria research and its contribution to the malaria control success in Suriname: a review Malar J 11 2012 95
45. U. D'Alessandro, and H. Buttiens History and importance of antimalarial drug resistance Trop Med Int Health 6 2001 845 848 (Pubitemid 33010869)
46. S. Pukrittayakamee, W. Supanaranond, S. Looareesuwan, S. Vanijanonta, and N.J. White Quinine in severe falciparum malaria: evidence of declining efficacy in Thailand Trans R Soc Trop Med Hyg 88 1994 324 327 (Pubitemid 24206458)
47. K. Kaur, M. Jain, S.I. Khan, M.R. Jacob, B.L. Tekwani, and S. Singh Synthesis, antiprotozoal, antimicrobial, beta-hematin inhibition, cytotoxicity and methemoglobin (MetHb) formation activities of bis(8-aminoquinolines) Bioorg Med Chem 19 2011 197 210
48. C.V. Plowe, C. Roper, J.W. Barnwell, C.T. Happi, H.H. Joshi, and W. Mbacham World Antimalarial Resistance Network (WARN) III: molecular markers for drug resistant malaria Malar J 6 2007 121
49. J. Bhisutthibhan, X.Q. Pan, P.A. Hossler, D.J. Walker, C.A. Yowell, and J. Carlton The Plasmodium falciparum translationally controlled tumor protein homolog and its reaction with the antimalarial drug artemisinin J Biol Chem 273 1998 16192 16198 (Pubitemid 28311392)
50. L. Cui, Z. Wang, H. Jiang, D. Parker, H. Wang, and X.Z. Su Lack of association of the S769N mutation in Plasmodium falciparum SERCA (PfATP6) with resistance to artemisinins Antimicrob Agents Chemother 56 2012 2546 2552
51. S.R. Meshnick Artemisinin: mechanisms of action, resistance and toxicity Int J Parasitol 32 2002 1655 1660 (Pubitemid 35339455)
52. F. ter Kuile, N.J. White, P. Holloway, G. Pasvol, and S. Krishna Plasmodium falciparum: in vitro studies of the pharmacodynamic properties of drugs used for the treatment of severe malaria Exp Parasitol 76 1993 85 95 (Pubitemid 23197907)
53. N.P. Aditya, G. Chimote, K. Gunalan, R. Banerjee, S. Patankar, and B. Madhusudhan Curcuminoids-loaded liposomes in combination with arteether protects against Plasmodium berghei infection in mice Exp Parasitol 131 2012 292 299
54. D. Bunnag, C. Viravan, S. Looareesuwan, J. Karbwang, and T. Harinasuta Double blind randomised clinical trial of oral artesunate at once or twice daily dose in falciparum malaria Southeast Asian J Trop Med Public Health 22 1991 539 543
55. R. McGready, M. Boel, M.J. Rijken, E.A. Ashley, T. Cho, and O. Moo Effect of early detection and treatment on malaria related maternal mortality on the north-Western border of Thailand 1986-2010 PLoS One 7 2012 e40244
56. A. Bell Antimalarial drug synergism and antagonism: mechanistic and clinical significance FEMS Microbiol Lett 253 2005 171 184 (Pubitemid 41674513)
57. A. Sabchareon, P. Attanath, P. Phanuaksook, P. Chanthavanich, Y. Poonpanich, and D. Mookmanee Efficacy and pharmacokinetics of atovaquone and proguanil in children with multidrug-resistant Plasmodium falciparum malaria Trans R Soc Trop Med Hyg 92 1998 201 206 (Pubitemid 28200803)
58. D.G. Heppner Jr., D.S. Walsh, N. Uthaimongkol, D.B. Tang, S. Tulyayon, and B. Permpanich Randomized, controlled, double-blind trial of daily oral azithromycin in adults for the prophylaxis of Plasmodium vivax malaria in Western Thailand Am J Trop Med Hyg 73 2005 842 849 (Pubitemid 41688456)
59. R.A. Kuschner, D.G. Heppner, S.L. Andersen, B.T. Wellde, T. Hall, and I. Schneider Azithromycin prophylaxis against a chloroquine-resistant strain of Plasmodium falciparum Lancet 343 1994 1396 1397 (Pubitemid 24167514)
60. I. Zeile, J.B. Gahutu, C. Shyirambere, C. Steininger, A. Musemakweri, and F. Sebahungu Molecular markers of Plasmodium falciparum drug resistance in southern highland Rwanda Acta Trop 121 2012 50 54
61. K.V. Sashidhara, M. Kumar, R.K. Modukuri, R.K. Srivastava, A. Soni, and K. Srivastava Antiplasmodial activity of novel keto-enamine chalcone-chloroquine based hybrid pharmacophores Bioorg Med Chem 20 2012 2971 2981
62. J. Marfurt, F. Chalfein, P. Prayoga, F. Wabiser, G. Wirjanata, and B. Sebayang Artemisinin-based combination therapy against P. vivax: Comparative ex vivo activity of next-generation endoperoxides in multidrug resistant field isolates Antimicrob Agents Chemother 2012 10.1128/AAC.00283-12
63. A.M. Lehane, C.A. McDevitt, K. Kirk, and D.A. Fidock Degrees of chloroquine resistance in Plasmodium - is the redox system involved? Int J Parasitol Drugs Drug Resist 2 2012 47 57
64. R. Brunner, H. Aissaoui, C. Boss, Z. Bozdech, R. Brun, and O. Corminboeuf Identification of a new chemical class of antimalarials J Infect Dis 206 2012 735 743
65. A.R. Anvikar, B. Sharma, S.K. Sharma, S.K. Ghosh, R.M. Bhatt, and A. Kumar In vitro assessment of drug resistance in Plasmodium falciparum in five States of India Indian J Med Res 135 2012 494 499
66. H.C. Rachel, T. Rafaelle, L.Q. Marie, C. Gerard, L. Bernard, and K. Fathi A cluster of acute diarrhea suspected to be cholera in French travelers in Haiti, December 2010 J Travel Med 19 2012 189 191
67. A. Corpolongo, P. De Nardo, P. Ghirga, E. Gentilotti, R. Bellagamba, and C. Tommasi Haemolytic anaemia in an HIV-infected patient with severe falciparum malaria after treatment with oral artemether-lumefantrine Malar J 11 2012 91
68. V. Duque, D. Seixas, C. Ventura, S. Da Cunha, and A. Melico-Silvestre Plasmodium falciparum malaria, bilateral sixth cranial nerve palsy and delayed cerebellar ataxia J Infect Dev Ctries 6 2012 290 294
69. G. Franken, I. Muller-Stover, M.C. Holtfreter, S. Walter, H. Mehlhorn, and A. Labisch Why do Plasmodium malariae infections sometimes occur in spite of previous antimalarial medication? Parasitol Res 111 2012 943 946
70. M.H. Irvine, A. Einarson, and P. Bozzo Prophylactic use of antimalarials during pregnancy Can Fam Physician 57 2011 1279 1281
71. F. Nosten, R. McGready, U. d'Alessandro, A. Bonell, F. Verhoeff, and C. Menendez Antimalarial drugs in pregnancy: a review Curr Drug Saf 1 2006 1 15
72. F. Nosten, and N.J. White Artemisinin-based combination treatment of falciparum malaria Am J Trop Med Hyg 77 2007 181 192
73. R.M. Fairhurst, B. Sadou, A. Guindo, D.A. Diallo, O.K. Doumbo, and T.E. Wellems Case report: life-threatening hypoglycaemia associated with sulfadoxine-pyrimethamine, a commonly used antimalarial drug Trans R Soc Trop Med Hyg 97 2003 595 596 (Pubitemid 40590102)
74. L.R. Dias, A.C. Freitas, E.J. Barreiro, D.K. Goins, D. Nanayakkara, and J.D. McChesney Synthesis and biological activity of new potential antimalarial: 1H-pyrazolo[3,4-b]pyridine derivatives Boll Chim Farm 139 2000 14 20 (Pubitemid 30252175)
75. C.C. Campbell, W.E. Collins, W.K. Milhous, J.M. Roberts, and A. Armstead Adaptation of the Indochina I/CDC strain of Plasmodium falciparum to the squirrel monkey (Saimiri sciureus) Am J Trop Med Hyg 35 1986 472 475 (Pubitemid 16089962)
76. M. Treiber, G. Wernsdorfer, U. Wiedermann, K. Congpuong, J. Sirichaisinthop, and W.H. Wernsdorfer Sensitivity of Plasmodium vivax to chloroquine, mefloquine, artemisinin and atovaquone in north-western Thailand Wien Klin Wochenschr 123 Suppl. 1 2011 20 25
77. M.T. Alam, D.K. de Souza, S. Vinayak, S.M. Griffing, A.C. Poe, and N.O. Duah Selective sweeps and genetic lineages of Plasmodium falciparum drug-resistant alleles in Ghana J Infect Dis 203 2011 220 227
78. C. Wongsrichanalai, and S.R. Meshnick Declining artesunate-mefloquine efficacy against falciparum malaria on the Cambodia-Thailand border Emerg Infect Dis 14 2008 716 719 (Pubitemid 351838633)
79. H. Mahgoub, G.I. Gasim, I.R. Musa, and I. Adam Severe Plasmodium vivax malaria among Sudanese children at New Halfa Hospital, Eastern Sudan Parasites Vectors 5 2012 154
80. K. Saravu, V. Acharya, K. Kumar, and R. Kumar Plasmodium vivax remains responsive to chloroquine with primaquine treatment regimen: a prospective cohort study from tertiary care teaching hospital in southern India Trop Doct 42 2012 163 164
81. P. Phompradit, J. Kuesap, W. Chaijaroenkul, R. Rueangweerayut, Y. Hongkaew, and R. Yamnuan Prevalence and distribution of glucose-6-phosphate dehydrogenase (G6PD) variants in Thai and Burmese populations in malaria endemic areas of Thailand Malar J 10 2011 368
82. S. Kim, C. Nguon, B. Guillard, S. Duong, S. Chy, and S. Sum Performance of the CareStart G6PD deficiency screening test, a point-of-care diagnostic for primaquine therapy screening PLoS One 6 2011 e28357
83. W.M. Ramos Junior, J.F. Sardinha, M.R. Costa, M.S. Santana, M.G. Alecrim, and M.V. Lacerda Clinical aspects of hemolysis in patients with P. vivax malaria treated with primaquine, in the Brazilian Amazon Braz J Infect Dis 14 2010 410 412
84. S.F. Drysdale, P.A. Phillips-Howard, and R.H. Behrens Proguanil, chloroquine, and mouth ulcers Lancet 335 1990 164 (Pubitemid 20032757)
85. A.M. Daniels Mouth ulceration associated with proguanil Lancet 1 1986 269 (Pubitemid 16132872)
86. F.H. Nogueira, L.M. Moreira-Campos, R.L. Santos, and G.A. Pianetti Quality of essential drugs in tropical countries: evaluation of antimalarial drugs in the Brazilian Health System Rev Soc Bras Med Trop 44 2011 582 586
87. J.L. Vieira, and A.F. Midio Drug monitoring of quinine in men with nonsevere falciparum malaria: study in the Amazon region of Brazil Ther Drug Monit 23 2001 612 615 (Pubitemid 33086487)
88. H. Habeeb, J.R. Ripper, A. Cohen, and P.B. Hinfey A Case of Imported Severe Plasmodium falciparum Malaria in the Emergency Department and the Current Role of Exchange Transfusion Treatment J Emerg Med 44 2013 e211 e215
89. A.M. Alkhunaizi, J.A. Al-Tawfiq, and M.H. Al-Shawaf Transfusion- transmitted malaria in a kidney transplant recipient. How safe is our blood transfusion? Saudi Med J 29 2008 293 295 (Pubitemid 351385137)
90. F.N. Boctor, and R.P. Dorion Malaria and hereditary elliptocytosis Am J Hematol 83 2008 753
91. C.R. Newton, and D.A. Warrell Neurological manifestations of falciparum malaria Ann Neurol 43 1998 695 702 (Pubitemid 28280212)
92. G.H. Posner, I.H. Paik, W. Chang, K. Borstnik, S. Sinishtaj, and A.S. Rosenthal Malaria-infected mice are cured by a single dose of novel artemisinin derivatives J Med Chem 50 2007 2516 2519 (Pubitemid 46799263)
93. K. Borstnik, I.H. Paik, T.A. Shapiro, and G.H. Posner Antimalarial chemotherapeutic peroxides: artemisinin, yingzhaosu A and related compounds Int J Parasitol 32 2002 1661 1667 (Pubitemid 35336007)
94. R.M. Fairhurst, G.M. Nayyar, J.G. Breman, R. Hallett, J.L. Vennerstrom, and S. Duong Artemisinin-resistant malaria: research challenges, opportunities, and public health implications Am J Trop Med Hyg 87 2012 231 241
95. A. Dorn, S.R. Vippagunta, H. Matile, C. Jaquet, J.L. Vennerstrom, and R.G. Ridley An assessment of drug-haematin binding as a mechanism for inhibition of haematin polymerisation by quinoline antimalarials Biochem Pharmacol 55 1998 727 736 (Pubitemid 28319636)
96. J.L. Vennerstrom, A.L. Ager Jr., S.L. Andersen, J.M. Grace, V. Wongpanich, and C.K. Angerhofer Assessment of the antimalarial potential of tetraoxane WR 148999 Am J Trop Med Hyg 62 2000 573 578 (Pubitemid 32210477)
97. J.L. Vennerstrom, Y. Dong, S.L. Andersen, A.L. Ager Jr., H. Fu, and R.E. Miller Synthesis and antimalarial activity of sixteen dispiro-1,2,4, 5-tetraoxanes: alkyl-substituted 7,8,15,16-tetraoxadispiro[5.2.5. 2]hexadecanes J Med Chem 43 2000 2753 2758 (Pubitemid 30463924)
98. U.S. Svensson, and M. Ashton Identification of the human cytochrome P450 enzymes involved in the in vitro metabolism of artemisinin Br J Clin Pharmacol 48 1999 528 535 (Pubitemid 29454233)
99. F. Teuscher, M.L. Gatton, N. Chen, J. Peters, D.E. Kyle, and Q. Cheng Artemisinin-induced dormancy in Plasmodium falciparum: duration, recovery rates, and implications in treatment failure J Infect Dis 202 2010 1362 1368
100. M. van Vugt, S. Looareesuwan, P. Wilairatana, R. McGready, L. Villegas, and I. Gathmann Artemether-lumefantrine for the treatment of multidrug-resistant falciparum malaria Trans R Soc Trop Med Hyg 94 2000 545 548
101. N.J. White, M. van Vugt, and F. Ezzet Clinical pharmacokinetics and pharmacodynamics and pharmacodynamics of artemether-lumefantrine Clin Pharmacokinet 37 1999 105 125
102. L. von Seidlein, K. Bojang, P. Jones, S. Jaffar, M. Pinder, and S. Obaro A randomized controlled trial of artemether/benflumetol, a new antimalarial and pyrimethamine/sulfadoxine in the treatment of uncomplicated falciparum malaria in African children Am J Trop Med Hyg 58 1998 638 644 (Pubitemid 28237264)
103. B. Tarnchompoo, C. Sirichaiwat, W. Phupong, C. Intaraudom, W. Sirawaraporn, and S. Kamchonwongpaisan Development of 2,4-diaminopyrimidines as antimalarials based on inhibition of the S108N and C59R+S108N mutants of dihydrofolate reductase from pyrimethamine-resistant Plasmodium falciparum J Med Chem 45 2002 1244 1252 (Pubitemid 34263561)
104. I.B. Muller, and J.E. Hyde Antimalarial drugs: modes of action and mechanisms of parasite resistance Future Microbiol 5 2010 1857 1873
105. A. Mital Recent advances in antimalarial compounds and their patents Curr Med Chem 14 2007 759 773 (Pubitemid 46477710)
106. J.N. Dominguez Chemotherapeutic agents against malaria: what next after chloroquine? Curr Top Med Chem 2 2002 1173 1185
107. L. Sun, F. Shah, M.A. Helal, Y. Wu, Y. Pedduri, and A.G. Chittiboyina Design, synthesis, and development of novel guaianolide-endoperoxides as potential antimalarial agents J Med Chem 53 2010 7864 7868
108. N. Kumura, H. Furukawa, A.N. Onyango, M. Izumi, S. Nakajima, and H. Ito Different behavior of artemisinin and tetraoxane in the oxidative degradation of phospholipid Chem Phys Lipids 160 2009 114 120
109. R.C. Reddy, P.G. Vatsala, V.G. Keshamouni, G. Padmanaban, and P.N. Rangarajan Curcumin for malaria therapy Biochem Biophys Res Commun 326 2005 472 474 (Pubitemid 39593570)
110. D.N. Nandakumar, V.A. Nagaraj, P.G. Vathsala, P. Rangarajan, and G. Padmanaban Curcumin-artemisinin combination therapy for malaria Antimicrob Agents Chemother 50 2006 1859 1860
111. B. Joe, M. Vijaykumar, and B.R. Lokesh Biological properties of curcumin-cellular and molecular mechanisms of action Crit Rev Food Sci Nutr 44 2004 97 111 (Pubitemid 38552286)
112. G. Shoba, D. Joy, T. Joseph, M. Majeed, R. Rajendran, and P.S. Srinivas Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers Planta Med 64 1998 353 356 (Pubitemid 28234275)
113. E. Roduner Size matters: why nanomaterials are different Chem Soc Rev 35 2006 583 592 (Pubitemid 43948237)
114. J.D. Steyn, L. Wiesner, L.H. du Plessis, A.F. Grobler, P.J. Smith, and W.C. Chan Absorption of the novel artemisinin derivatives artemisone and artemiside: potential application of Pheroid technology Int J Pharm 414 2011 260 266
115. C. Slabbert, L.H. Plessis, and A.F. Kotze Evaluation of the physical properties and stability of two lipid drug delivery systems containing mefloquine Int J Pharm 409 2011 209 215
116. A.D. Bangham, M.M. Standish, and J.C. Watkins Diffusion of univalent ions across the lamellae of swollen phospholipids J Mol Biol 13 1965 238 252
117. B. Isacchi, M.C. Bergonzi, M. Grazioso, C. Righeschi, A. Pietretti, and C. Severini Artemisinin and artemisinin plus curcumin liposomal formulations: enhanced antimalarial efficacy against Plasmodium berghei-infected mice Eur J Pharm Biopharm 80 2012 528 534
118. P. Urban, J. Estelrich, A. Cortes, and X. Fernandez-Busquets A nanovector with complete discrimination for targeted delivery to Plasmodium falciparum-infected versus non-infected red blood cells in vitro J Control Release 151 2011 202 211
119. P. Urban, J. Estelrich, A. Adeva, A. Cortes, and X. Fernandez-Busquets Study of the efficacy of antimalarial drugs delivered inside targeted immunoliposomal nanovectors Nanoscale Res Lett 6 2011 620
120. M. Gabriels, and J. Plaizier-Vercammen Physical and chemical evaluation of liposomes, containing artesunate J Pharm Biomed Anal 31 2003 655 667 (Pubitemid 36315707)
121. M.A. Atemnkeng, B. Chimanuka, B. Dejaegher, Y.V. Heyden, and J. Plaizier-Vercammen Evaluation of Artemisia annua infusion efficacy for the treatment of malaria in Plasmodium chabaudi chabaudi infected mice Exp Parasitol 122 2009 344 348
122. B. Chimanuka, M. Gabriels, M.R. Detaevernier, and J.A. Plaizier-Vercammen Preparation of beta-artemether liposomes, their HPLC-UV evaluation and relevance for clearing recrudescent parasitaemia in Plasmodium chabaudi malaria-infected mice J Pharm Biomed Anal 28 2002 13 22 (Pubitemid 34171642)
123. A.A. Al-Angary, M.A. Al-Meshal, M.A. Bayomi, and S.H. Khidr Evaluation of liposomal formulations containing the antimalarial agent arteether Int J Pharm 128 1996 163 168 (Pubitemid 26092153)
124. M.A. Bayomi, A.A. Al-Angary, M.A. Al-Meshal, and M.M. Al-Dardiri In vivo evaluation of arteether liposomes Int J Pharm 175 1998 1 7 (Pubitemid 28487010)
125. M. Owais, G.C. Varshney, A. Choudhury, S. Chandra, and C.M. Gupta Chloroquine encapsulated in malaria-infected erythrocyte-specific antibody-bearing liposomes effectively controls chloroquine-resistant Plasmodium berghei infections in mice Antimicrob Agents Chemother 39 1995 180 184
126. P.A. Peeters, B.G. Brunink, W.M. Eling, and D.J. Crommelin Therapeutic effect of chloroquine(CQ)-containing immunoliposomes in rats infected with Plasmodium berghei parasitized mouse red blood cells: comparison with combinations of antibodies and CQ or liposomal CQ Biochim Biophys Acta 981 1989 269 276 (Pubitemid 19149722)
127. P.A. Peeters, K. de Leest, W.M. Eling, and D.J. Crommelin Chloroquine blood levels after administration of the liposome-encapsulated drug in relation to therapy of murine malaria Pharm Res 6 1989 787 793 (Pubitemid 19247849)
128. D.J.A. Crommelin, U.K. Nässander, P.A.M. Peeters, P.A. Steerenberg, W.H. de Jong, and W.M.C. Eling Drug-laden liposomes in antitumor therapy and in the treatment of parasitic diseases J Control Release 11 1990 233 243 (Pubitemid 20070101)
129. D.J.A. Crommelin, W.M.C. Eling, P.A. Steerenberg, U.K. Nässander, G. Storm, and W.H. DeJong Liposomes and immunoliposomes for controlled release or site specific delivery of antiparasitic drugs and cystostatics J Control Release 16 1991 147 154
130. L. Qiu, N. Jing, and Y. Jin Preparation and in vitro evaluation of liposomal chloroquine diphosphate loaded by a transmembrane pH-gradient method Int J Pharm 361 2008 56 63
131. N.S. Postma, D.J. Crommelin, W.M. Eling, and J. Zuidema Treatment with liposome-bound recombinant human tumor necrosis factor-alpha suppresses parasitemia and protects against Plasmodium berghei k173-induced experimental cerebral malaria in mice J Pharmacol Exp Ther 288 1999 114 120 (Pubitemid 29113481)
132. K.J. Longmuir, R.T. Robertson, S.M. Haynes, J.L. Baratta, and A.J. Waring Effective targeting of liposomes to liver and hepatocytes in vivo by incorporation of a Plasmodium amino acid sequence Pharm Res 23 2006 759 769
133. A.H. Price, and K.A. Fletcher Ethnic differences in the reactions to drugs and xenobiotics. The metabolism and toxicity of primaquine Prog Clin Biol Res 214 1986 261 278
134. A.K. Agrawal, A. Singhal, and C.M. Gupta Functional drug targeting to erythrocytes in vivo using antibody bearing liposomes as drug vehicles Biochem Biophys Res Commun 148 1987 357 361 (Pubitemid 17146325)
135. G. Stensrud, S.A. Sande, S. Kristensen, and G. Smistad Formulation and characterisation of primaquine loaded liposomes prepared by a pH gradient using experimental design Int J Pharm 198 2000 213 228 (Pubitemid 30184858)
136. J.E. Smith, P. Pirson, and R.E. Sinden Studies on the kinetics of uptake and distribution of free and liposome-entrapped primaquine, and of sporozoites by isolated perfused rat liver Ann Trop Med Parasitol 77 1983 379 386 (Pubitemid 13002410)
137. P. Pirson, R. Steiger, and A. Trouet The disposition of free and liposomally encapsulated antimalarial primaquine in mice Biochem Pharmacol 31 1982 3501 3507 (Pubitemid 13234515)
138. B. Arica, A.Y. Ozer, M.T. Ercan, and A.A. Hincal Characterization, in vitro and in vivo studies on primaquine diphosphate liposomes J Microencapsul 12 1995 469 485
139. S.M. Haynes, K.J. Longmuir, R.T. Robertson, J.L. Baratta, and A.J. Waring Liposomal polyethyleneglycol and polyethyleneglycol-peptide combinations for active targeting to liver in vivo Drug Deliv 15 2008 207 217 (Pubitemid 351630931)
140. N.S. Postma, C.C. Hermsen, J. Zuidema, and W.M. Eling Plasmodium vinckei: optimization of desferrioxamine B delivery in the treatment of murine malaria Exp Parasitol 89 1998 323 330 (Pubitemid 28375780)
141. S. Casares, T.D. Brumeanu, and T.L. Richie The RTS,S malaria vaccine Vaccine 28 2010 4880 4894
142. J.N. Verma, M. Rao, S. Amselem, U. Krzych, C.R. Alving, and S.J. Green Adjuvant effects of liposomes containing lipid A: enhancement of liposomal antigen presentation and recruitment of macrophages Infect Immun 60 1992 2438 2444
143. S.K. Sharma, C. Gupta, V. Dwivedi, S. Misra-Bhattacharya, and O. Mohammad Prophylactic potential of liposomized integral membrane protein of Plasmodium yoelii nigeriensis against blood stage infection in BALB/c mice Vaccine 25 2007 2103 2111 (Pubitemid 46227668)
144. P. Shahgaldian, E. Da Silva, A.W. Coleman, B. Rather, and M.J. Zaworotko Para-acyl-calix-arene based solid lipid nanoparticles (SLNs): a detailed study of preparation and stability parameters Int J Pharm 253 2003 23 38 (Pubitemid 36197828)
145. E.B. Souto, and R.H. Muller Lipid nanoparticles: effect on bioavailability and pharmacokinetic changes Handb Exp Pharmacol 2010 115 141
146. W. Mehnert, and K. Mader Solid lipid nanoparticles: production, characterization and applications Adv Drug Deliv Rev 47 2001 165 196 (Pubitemid 32324113)
147. Muller RH, Lucks JS. Arzneistofftrager aus festen Lipidteilchen, Feste Lipidnanosphären (SLN). European Patent No EP 0605497. 1996.
148. Gasco MR. Method for producing solid lipid microspheres having a narrow size distribution. US Patent No 5250236. 1993.
149. A.P. Nayak, W. Tiyaboonchai, S. Patankar, B. Madhusudhan, and E.B. Souto Curcuminoids-loaded lipid nanoparticles: novel approach towards malaria treatment Colloids Surf B Biointerfaces 81 2010 263 273
150. A.P. Nayak, W. Tiyaboonchai, S. Patankar, B. Madhusudhan, and E.B. Souto Curcuminoids-loaded lipid nanoparticles: novel approach towards malaria treatment Colloids Surf B Biointerfaces 81 2010 263 273
151. N.P. Aditya, S. Patankar, B. Madhusudhan, R.S. Murthy, and E.B. Souto Arthemeter-loaded lipid nanoparticles produced by modified thin-film hydration: pharmacokinetics, toxicological and in vivo anti-malarial activity Eur J Pharm Sci 40 2010 448 455
152. X. Zhang, J. Liu, H. Qiao, H. Liu, J. Ni, and W. Zhang Formulation optimization of dihydroartemisinin nanostructured lipid carrier using response surface methodology Powder Technol 197 2010 120 128
153. M. Joshi, S. Pathak, S. Sharma, and V. Patravale Design and in vivo pharmacodynamic evaluation of nanostructured lipid carriers for parenteral delivery of artemether: nanoject Int J Pharm 364 2008 119 126
154. Y. Gupta, A. Jain, and S.K. Jain Transferrin-conjugated solid lipid nanoparticles for enhanced delivery of quinine dihydrochloride to the brain J Pharm Pharmacol 59 2007 935 940 (Pubitemid 47051073)
155. E.B. Souto, N.P. Aditya, and R.S.R. Murthy Lipid nanoemulsions for anticancer drug therapy Pharmazie 66 2011 1 6
156. A.M. Dierling, and Z. Cui Targeting primaquine into liver using chylomicron emulsions for potential vivax malaria therapy Int J Pharm 303 2005 143 152 (Pubitemid 41318031)
157. K.K. Singh, and S.K. Vingkar Formulation, antimalarial activity and biodistribution of oral lipid nanoemulsion of primaquine Int J Pharm 347 2008 136 143 (Pubitemid 350180322)
158. M. Joshi, S. Pathak, S. Sharma, and V. Patravale Solid microemulsion preconcentrate (NanOsorb) of artemether for effective treatment of malaria Int J Pharm 362 2008 172 178
159. I. Henriksen, S.R. Våagen, S.A. Sande, G. Smistad, and J. Karlsen Interactions between liposomes and chitosan II: effect of selected parameters on aggregation and leakage Int J Pharm 146 1997 193 204
160. P.V.C. Covreur Nanotechnology: intelligent design to treat complex disease Pharm Res 23 2006 1417 1450
161. P.R. Lockman, R.J. Mumper, M.A. Khan, and D.D. Allen Nanoparticle technology for drug delivery across the blood-brain barrier Drug Dev Ind Pharm 28 2002 1 13 (Pubitemid 34279373)
162. G. Barratt Colloidal drug carriers: achievements and perspectives Cell Mol Life Sci 60 2003 21 37 (Pubitemid 36223115)
163. C.C.P. Vauthier Nanomedicines: a new approach for the treatment of serious diseases J Biomed Nanotechnol 3 2007 223 234
164. T.Z.N. Xu, H.L. Nichols, D. Shi, and X. Wen Modification of nanostructured materials for biomedical applications Mater Sci Eng C 27 2007 579 594 (Pubitemid 46281627)
165. F. Akhtar, M.M. Rizvi, and S.K. Kar Oral delivery of curcumin bound to chitosan nanoparticles cured Plasmodium yoelii infected mice Biotechnol Adv 30 2012 310 320
166. R. Surolia, M. Pachauri, and P.C. Ghosh Preparation and characterization of monensin loaded PLGA nanoparticles: in vitro anti-malarial activity against Plasmodium falciparum J Biomed Nanotechnol 8 2012 172 181
167. P.P. Dandekar, R. Jain, S. Patil, R. Dhumal, D. Tiwari, and S. Sharma Curcumin-loaded hydrogel nanoparticles: application in anti-malarial therapy and toxicological evaluation J Pharm Sci 99 2010 4992 5010
168. F. Foger, W. Noonpakdee, B. Loretz, S. Joojuntr, W. Salvenmoser, and M. Thaler Inhibition of malarial topoisomerase II in Plasmodium falciparum by antisense nanoparticles Int J Pharm 319 2006 139 146 (Pubitemid 44051799)
169. P.P. Pednekar, K.R. Jadhav, and V.J. Kadam Aptamer-dendrimer bioconjugate: a nanotool for therapeutics, diagnosis, and imaging Expert Opin Drug Deliv 9 2012 1273 1288
170. E. Lallana, F. Fernandez-Trillo, A. Sousa-Herves, R. Riguera, and E. Fernandez-Megia Click chemistry with polymers, dendrimers, and hydrogels for drug delivery Pharm Res 29 2012 902 921
171. D. Bhadra, S. Bhadra, and N.K. Jain PEGylated peptide-based dendritic nanoparticulate systems for delivery of artemether J Drug Deliv Sci Technol 15 2005 65 73 (Pubitemid 40208981)
172. D. Bhadra, S. Bhadra, and N.K. Jain PEGylated peptide dendrimeric carriers for the delivery of antimalarial drug chloroquine phosphate Pharm Res 23 2006 623 633
173. D. Bhadra, A.K. Yadav, S. Bhadra, and N.K. Jain Glycodendrimeric nanoparticulate carriers of primaquine phosphate for liver targeting Int J Pharm 295 2005 221 233 (Pubitemid 40558805)
174. M. Gomes, I. Ribeiro, M. Warsame, H. Karunajeewa, and M. Petzold Rectal artemisinins for malaria: a review of efficacy and safety from individual patient data in clinical studies BMC Infect Dis 8 2008 39
175. D. Gugulothu, S. Pathak, S. Suryavanshi, S. Sharma, and V. Patravale Self-microemulsifiyng suppository formulation of beta-artemether AAPS PharmSciTech 11 2010 1179 1184
176. S.D. Mandawgade, S. Sharma, S. Pathak, and V.B. Patravale Development of SMEDDS using natural lipophile: application to beta-Artemether delivery Int J Pharm 362 2008 179 183
177. M.E. Brewster, and T. Loftsson Cyclodextrins as pharmaceutical solubilizers Adv Drug Deliv Rev 59 2007 645 666 (Pubitemid 47299263)
178. J.W. Wong, and K.H. Yuen Inclusion complexation of artemisinin with alpha-, beta-, and gamma-cyclodextrins Drug Dev Ind Pharm 29 2003 1035 1044 (Pubitemid 37346105)
179. I.E. Crandall, W.A. Szarek, J.Z. Vlahakis, Y. Xu, R. Vohra, and J. Sui Sulfated cyclodextrins inhibit the entry of Plasmodium into red blood cells. Implications for malarial therapy Biochem Pharmacol 73 2007 632 642 (Pubitemid 46172457)
180. M.G. Hartell, R. Hicks, A.K. Bhattacharjee, B.W. Koser, K. Carvalho, and J.E. Van Hamont Nuclear magnetic resonance and molecular modeling analysis of the interaction of the antimalarial drugs artelinic acid and artesunic acid with beta-cyclodextrin J Pharm Sci 93 2004 2076 2089 (Pubitemid 39045488)
181. M.T. Ansari, I. Iqbal, and V.B. Sunderland Dihydroartemisinin- cyclodextrin complexation: solubility and stability Arch Pharm Res 32 2009 155 165
182. C.O. Onyeji, S.I. Omoruyi, and F.A. Oladimeji Dissolution properties and characterization of halofantrine-2-hydroxypropyl-beta-cyclodextrin binary systems Pharmazie 62 2007 858 863 (Pubitemid 350144621)
183. M.J. Ku, F.M. Dossin, Y. Choi, C.B. Moraes, J. Ryu, and R. Song Quantum dots: a new tool for anti-malarial drug assays Malar J 10 2011 118
184. K. Huikko, R. Kostiainen, and T. Kotiaho Introduction to micro-analytical systems: bioanalytical and pharmaceutical applications Eur J Pharm Sci 20 2003 149 171 (Pubitemid 37205209)
185. P. Gascoyne, J. Satayavivad, and M. Ruchirawat Microfluidic approaches to malaria detection Acta Trop 89 2004 357 369 (Pubitemid 38117072)
186. G. Rajakumar, and Rahuman A. Abdul Larvicidal activity of synthesized silver nanoparticles using Eclipta prostrata leaf extract against filariasis and malaria vectors Acta Trop 118 2011 196 203
187. T. Santhoshkumar, A.A. Rahuman, G. Rajakumar, S. Marimuthu, A. Bagavan, and C. Jayaseelan Synthesis of silver nanoparticles using Nelumbo nucifera leaf extract and its larvicidal activity against malaria and filariasis vectors Parasitol Res 108 2011 693 702
188. B.M. Greenwood, D.A. Fidock, D.E. Kyle, S.H. Kappe, P.L. Alonso, and F.H. Collins Malaria: progress, perils, and prospects for eradication J Clin Invest 118 2008 1266 1276 (Pubitemid 351500419)
189. S. Krishna, L. Bustamante, R.K. Haynes, and H.M. Staines Artemisinins: their growing importance in medicine Trends Pharmacol Sci 29 2008 520 527
190. G.A. Biagini, S.A. Ward, and P.G. Bray Malaria parasite transporters as a drug-delivery strategy Trends Parasitol 21 2005 299 301 (Pubitemid 40807171)
191. K. Haldar, and L. Uyetake The movement of fluorescent endocytic tracers in Plasmodium falciparum infected erythrocytes Mol Biochem Parasitol 50 1992 161 177
192. B. Pouvelle, J.A. Gormley, and T.F. Taraschi Characterization of trafficking pathways and membrane genesis in malaria-infected erythrocytes Mol Biochem Parasitol 66 1994 83 96 (Pubitemid 24250055)
193. E.R. Burns, and S.P. Pollack falciparum infected erythrocytes are capable of endocytosis In Vitro Cell Dev Biol 24 1988 481 486
194. K.T. Tokuyasu, R. Schekman, and S.J. Singer Domains of receptor mobility and endocytosis in the membranes of neonatal human erythrocytes and reticulocytes are deficient in spectrin J Cell Biol 80 1979 481 486 (Pubitemid 9091520)
195. A. Kilejian The biosynthesis of the knob protein and a 65 000 dalton histidine-rich polypeptide of Plasmodium falciparum Mol Biochem Parasitol 12 1984 185 194 (Pubitemid 14030498)
196. Y. Yuthavong, P. Wilairat, B. Panijpan, C. Potiwan, and G.H. Beale Alteration in membrane proteins of mouse erythrocytes infected with different species and strains of malaria parasites Comp Biochem Physiol 63B 1979 83 85 (Pubitemid 9185390)
197. B.S.S. Rothen-Rutishauser, B. Haenni, N. Kapp, and P. Gehr Interaction of fine particles and nanoparticles with red blood cells visualized with advanced microscopic techniques Environ Sci Technol 40 2006 4353 4359 (Pubitemid 44092367)
198. I.D. Goodyer, B. Pouvelle, T.G. Schneider, D.P. Trelka, and T.F. Taraschi Characterization of macromolecular transport pathways in malaria-infected erythrocytes Mol Biochem Parasitol 87 1997 13 28 (Pubitemid 27308849)
199. S.A. Lauer, P.K. Rathod, N. Ghori, and K. Haldar A membrane network for nutrient import in red cells infected with the malaria parasite Science 276 1997 1122 1125 (Pubitemid 27218122)
200. B. Pouvelle, and J. Gysin Presence of the parasitophorous duct in Plasmodium falciparum and P. vivax parasitized Saimiri monkey red blood cells Parasitol Today 13 1997 357 361 (Pubitemid 27364609)
201. B. Pouvelle, R. Spiegel, L. Hsiao, R.J. Howard, R.L. Morris, and A.P. Thomas Direct access to serum macromolecules by intraerythrocytic malaria parasites Nature 353 1991 73 75 (Pubitemid 21912459)
202. J.E. Bodammer, and G.F. Bahr The initiation of a "metabolic window" in the surface of host erythrocytes by Plasmodium berghei NYU-2 Lab Invest 28 1973 708 718
203. C. Bracho, I. Dunia, L.R. De, E.L. Benedetti, and H.A. Perez Traffic pathways of Plasmodium vivax antigens during intraerythrocytic parasite development Parasitol Res 88 2002 253 258 (Pubitemid 34146603)
204. H. Wickert, F. Wissing, K.T. Andrews, A. Stich, G. Krohne, and M. Lanzer Evidence for trafficking of PfEMP1 to the surface of P. falciparum-infected erythrocytes via a complex membrane network Eur J Cell Biol 82 2003 271 284 (Pubitemid 36818151)
205. J. Kanaani, and H. Ginsburg Effects of cinnamic acid derivatives on in vitro growth of Plasmodium falciparum and on the permeability of the membrane of malaria-infected erythrocytes Antimicrob Agents Chemother 36 1992 1102 1108
206. J.M. Upston, and A.M. Gero Parasite-induced permeation of nucleosides in Plasmodium falciparum malaria Biochim Biophys Acta 1236 1995 249 258
207. H. Ginsburg, and W.D. Stein New permeability pathways induced by the malarial parasite in the membrane of its host erythrocyte: potential routes for targeting of drugs into infected cells Biosci Rep 7 1987 455 463
208. K. Kirk Membrane transport in the malaria-infected erythrocyte Physiol Rev 81 2001 495 537 (Pubitemid 32267072)