Absorption of the novel artemisinin derivatives artemisone and artemiside: Potential application of Pheroid™ technology

International Journal of Pharmaceutics

Volumn 414, Issue 1-2, 2011, Pages 260-266

  Steyn, J Dewald ^a   Wiesner, Lubbe ^b   Du Plessis, Lissinda H ^a   Grobler, Anne F ^a   Smith, Peter J ^b   Chan, Wing Chi ^c   Haynes, Richard K ^c   Kotzé, Awie F ^a  

^a NORTH WEST UNIVERSITY   (South Africa)

^b UNIVERSITY OF CAPE TOWN   (South Africa)

^c HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

Artemiside; Artemisone; Malaria; Pharmacokinetic analysis; Pheroid technology

Indexed keywords

ARTEMISIDE; ARTEMISININ DERIVATIVE; ARTEMISONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIMALARIAL ACTIVITY; ARTICLE; BLOOD SAMPLING; BRAIN MALARIA; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG SOLUBILITY; DRUG TRANSPORT; LIQUID CHROMATOGRAPHY; MALARIA; MASS SPECTROMETRY; MONOTHERAPY; MOUSE; NONHUMAN; PRIORITY JOURNAL; TECHNOLOGY;

ABSORPTION; ADMINISTRATION, ORAL; ALPHA-TOCOPHEROL; ANIMALS; ANTIMALARIALS; ARACHIDONIC ACID; ARTEMISININS; COLLOIDS; DRUG CARRIERS; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; EXCIPIENTS; GLYCEROL; MALARIA, CEREBRAL; MALE; MICE; MICE, INBRED C57BL; PARTICLE SIZE; PLASMODIUM; VITAMINS;

EID: 79959747614     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.05.003     Document Type: Article

References (18)

1. J.K. Baird Effectiveness of antimalarial drugs N. Engl. J. Med. 352 2005 1565 1577
2. L.K. Basco, P. Ringwald, J.F. Franetich, and D. Mazier Assessment of pyronaridine activity in vivo and in vitro against the hepatic stages of malaria in laboratory mice Trans. R. Soc. Trop. Med. Hyg. 93 1999 651 652 (Pubitemid 30015797)
3. A.M. Dondorp, F. Nosten, P. Yi, D. Das, A.P. Phyo, J. Tarning, K.M. Lwin, F. Ariey, W. Hanpithakpong, S.J. Lee, P. Ringwald, K. Silamut, M. Imwong, K. Chitovanich, P. Lim, T. Herdman, S.S. An, S. Yeung, P. Singhasivanon, N.P.J. Day, N. Lindegardh, D. Socheat, and N.J. White Artemisinin resistance in Plasmodium falciparum malaria N. Engl. J. Med. 361 2009 455 467
4. E. Gkrania-Klotsas, and A.M.L. Lever An update on malaria prevention, diagnosis and treatment for the returning traveller Blood Rev. 21 2006 73 87
5. A. Grobler, A.F. Kotzé, and J. Du Plessis The design of a skin-friendly carrier for cosmetic compounds using Pheroid™ technology J. Wiechers, Science and Applications of Skin Delivery Systems 2008 Allured Publishing Corporation Wheaton, IL
6. S.I. Hay, C.A. Guerra, A.J. Tatem, A.M. Noor, and R.W. Snow The global distribution and population at risk of malaria: past, present, and future Lancet: Infect. Dis. 4 2004 327 336 (Pubitemid 38692697)
7. R.K. Haynes, B. Fugmann, J. Stetter, K. Rieckmann, H.D. Heilmann, H.W. Chan, M.K. Cheung, W.L. Lam, H.N. Wong, S.L. Croft, L. Vivas, L. Rattray, L. Stewart, W. Peters, B.L. Robinson, M.D. Edstein, B. Kotecka, D.E. Kyle, B. Beckermann, M. Gerisch, M. Radtke, G. Schmuck, W. Steinke, U. Wollborn, K. Schmeer, and A. Röhmer Artemisone - a highly active antimalarial drug of the artemisinin class Angew. Chem. Int. Ed. 45 2006 2082 2088 (Pubitemid 44105182)
8. C. Jonker, J.H. Hamman, and A.F. Kotzé Intestinal paracellular permeation enhancement with quaternised chitosan: in situ and in vitro evaluation Int. J. Pharm. 238 2002 205 213 (Pubitemid 34457889)
9. S. Krishna, A.C. Uhlemann, and R.K. Haynes Artemisinins: mechanisms of action and potential for resistance Drug Resist. Updat. 7 2004 233 244 (Pubitemid 39469096)
10. S.R. Meshnick, T.E. Taylor, and S. Kamchonwonpaisan Artemisinin and the antimalarial endoperoxides: from herbal remedy to targeted chemotherapy Microbiol. Rev. 60 1996 301 315 (Pubitemid 26171692)
11. T.K. Mutabingwa Artemisinin-based combination therapies (ACTs): best hope for malaria treatment but inaccessible to the needy Acta Trop. 95 2005 305 315 (Pubitemid 41207297)
12. E.A. Ojo-Amaize, E.J. Nchekwube, H.B. Cottam, O.A. Oyemade, A.A. Adesomoju, and J.I. Okogun Plasmodium berghei: antiparasitic effects of orally administered hypoestoxide in mice Exp. Parasitol. 117 2007 218 221 (Pubitemid 47331442)
13. T. Velkov, S. Chuang, J. Wielens, H. Sakkelaris, W.N. Charman, C.J.H. Porter, and M.J. Scanlon The interaction of lipophilic drugs with intestinal fatty acid-binding protein J. Biol. Chem. 280 2005 17769 17776 (Pubitemid 41389015)
14. N.J. White Antimalarial drug resistance J. Clin. Invest. 113 2004 1084 1092 (Pubitemid 38544090)
15. J.W. Wong, and K.H. Yuen Improved oral bioavailability of artemisinin through inclusion complexation with β- and γ-cyclodextrins Int. J. Pharm. 227 2001 177 185 (Pubitemid 32868771)
16. C.J. Woodrow, R.K. Haynes, and S. Krishna Artemisinins Postgrad. Med. J. 81 2005 71 78 (Pubitemid 40282867)
17. World Health Organization (WHO) Guidelines for the Treatment of Malaria 2006 266 pp.
18. World Health Organization (WHO) International Travel and Health. Situation as on January 2009 2009 250 pp. http://www.scribd.com/doc/19637506/ International-travel-and-health (accessed on 16.11.09)