Formulation optimization of dihydroartemisinin nanostructured lipid carrier using response surface methodology

Powder Technology

Volumn 197, Issue 1-2, 2010, Pages 120-128

  Zhang, Xiaoyun ^a,b   Liu, Jianping ^a   Qiao, Hua ^b   Liu, Huan ^a   Ni, Jingman ^b   Zhang, Wenli ^a   Shi, Yanbin ^b  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b LANZHOU UNIVERSITY   (China)

Author keywords

Central composite rotatable design; Dihydroartemisinin; Nanostructured lipid carrier; Response surface methodology

Indexed keywords

CENTRAL COMPOSITE ROTATABLE DESIGN; DIHYDROARTEMISININ; DRUG ENCAPSULATION EFFICIENCY; DRUG LOADING; FACTORIAL DESIGN; FORMULATION OPTIMIZATION; IN-VITRO; INDEPENDENT VARIABLES; LIPID CONCENTRATION; MEAN DIAMETER; NANOSTRUCTURED LIPID CARRIER; NANOSTRUCTURED LIPID CARRIERS; OPTIMAL FORMULATION; OPTIMIZED CONDITIONS; POLYDISPERSITY INDICES; RESPONSE SURFACE METHODOLOGY; SPHERICAL PARTICLE; TEM; TOTAL LIPIDS;

CONCENTRATION (PROCESS); DESIGN; ENCAPSULATION; LIQUIDS; POLYDISPERSITY; SURFACE PROPERTIES; ZETA POTENTIAL;

OPTIMIZATION;

DIHYDROARTEMISININ; GLYCEROL STEARATE; MIGLYOL; NANOMATERIAL;

ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DISPERSION; DRUG FORMULATION; DRUG RELEASE; DRUG STRUCTURE; ENCAPSULATION; FACTORIAL ANALYSIS; IN VITRO STUDY; PARTICLE SIZE; RESPONSE SURFACE METHOD; ZETA POTENTIAL;

EID: 70350074027     PISSN: 00325910     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.powtec.2009.09.004     Document Type: Article

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