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Volumn 19, Issue 1, 2011, Pages 197-210
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Synthesis, antiprotozoal, antimicrobial, β-hematin inhibition, cytotoxicity and methemoglobin (MetHb) formation activities of bis(8-aminoquinolines)
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Author keywords
8 Aminoquinolines; Bisquinolines; Malaria; Primaquine
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Indexed keywords
8 AMINOQUINOLINE DERIVATIVE;
[[4 [(6 METHOXYQUINOLIN 8 YL)AMINO]PENTYL]AMINO] METHYL [4 [(6 METHOXYQUINOLIN 8 YL)AMINO]PENTYL] CARBAMATE 2 HYDROCHLORIDE;
ANTIFUNGAL AGENT;
ANTIINFECTIVE AGENT;
ANTILEISHMANIAL AGENT;
ANTIMALARIAL AGENT;
ANTIPROTOZOAL AGENT;
BENZYL [5 [[4 [(6 METHOXYQUINOLIN 8 YL)AMINO]PENTYL]AMINO] 4 [[[4 [(6 METHOXYQUINOLIN8 YL)AMINO]PENTYL]CARBAMOYL]AMINO] 5 OXOPENTYL]CARBAMATE;
BENZYL [6 [[4 [(METHOXYQUINOLIN 8 YL)AMINO]PENTYL]AMINO] 5 [[[4 [(METHOXYQUINOLIN 8 YL)AMINO]PENTYL]CARBAMOYL]AMINO] 6 OXOHEXYL]CARBAMATE;
BENZYL[5 [[4 [(2 TERT BUTYL 6 METHOXYQUINOLIN 8 YL)PENTYL]AMINO] 4 [[[4 [(2 TERT BUTYL 6 METHOXYQUINOLIN 8 YL]AMINO]PENTYL]CARBAMOYL]AMINO] 5 OXOPENTYL]CARBAMATE;
BENZYL[6 [[4 [(2 TERT BUTYL 6 METHOXYQUINOLIN 8 YL)AMINO]PENTYL]AMINO] 5 [[[4 [(2 TERT BUTYL 6 METHOXYQUINOLIN 8 YL)AMINO]PENTYL]CARBAMOYL]AMINO] 6 OXOHEXYL]CARBAMATE;
BENZYL[N [(BENZYLOXY)CARBONYL] N [5 [[4 [(6 METHOXYQUINOLIN 8 YL)AMINO]PENTYL]AMINO] 4 [[[4 [(5 METHOXYQUINOLIN 8 YL)AMINO]PENTYL]CARBAMOYL]AMINO] 5 OXOPENTYL]CARBAMIMIDOYL]CARBAMATE;
BETA HEMATIN;
CYTOTOXIC AGENT;
HEMATIN;
METHEMOGLOBIN;
N [4 [(2 TERT BUTYL 5 METHOXYQUINOLIN 8 YL)AMINO]PENTYL] N2 [[4 [(2 TERT BUTYL 6 METHOXYQUINOLIN 8 YL)AMINO]PENTYL]CARBAMOYL] LEVO LYSINAMIDE 3 HYDROCHLORIDE;
N [4 [(6 METHOXYQUINOLIN 8 YL)AMINO]PENTYL] N2 [[4 [(6 METHOXYQUINOLIN 8 YL)AMINO]PENTYL]CARBAMOYL] LEVO LYSINAMIDE 3 HYDROCHLORIDE;
N [4 [(6 METHOXYQUINOLIN 8 YL)AMINO]PENTYL]N2 [[4 [(6 METHOXYQUINOLIN 8 YL)AMINO]PENTYL]CARBAMOYL] N5 [N [(2,2,5 7,8 PENTAMETHYL 3,4 DIHYDRO 2H CHROMEN 6 YL)SULFONYL]CARBAMIMIDOYL] L ORNITHINAMIDE;
N [4 [(METHOXYQUINOLIN 8 YL)AMINO]PENTYL] N2 [[4 [(6 METHOXYQUINOLIN 8 YL)AMINO]PENTYL]CARBAMOYL] DEXTRO ARGININAMIDE 3 HYDROCHLORIDE;
N,N2 BIS [4 [(2 TERT BUTYL 6 METHOXYQUINOLIN 8 YL)AMINO]PENTYL] GLYCINAMIDE 2 HYDROCHLORIDE;
N1,N1 (IMINODIETHANE 2,1 DIYL)BIS[N4 (6 METHOXYQUINOLIN 8 YL)PENTANE 1,4 DIAMINE] 2 HYDROCHLORIDE;
N1,N1 (IMINODIETHANE 2,1 DIYL)BIS[N4 6 METHOXYQUINOLIN 8 YL)PENTANE 1,4 DIAMINE] 2 HYDROCHLORIDE;
N1,N5 BIS [4 [(6 METHOXYQUINOLIN 8 YL)AMINO]PENTYL] LEVO GLUTAMAMIDE 3 HYDROCHLORIDE;
PRIMAQUINE;
TERT BUTYL [5 [[4 [(2 TERT BUTYL 6 METHOXYQUINOLIN 8 YL)AMINO]PENTYL]AMINO] 4 [[[4 [(2 TERT BUTYL 6 METHOXYQUINOLIN 8 YL)AMINO]PENTYL]CARBAMOYL]AMINO] 5 OXOPENTYL]CARBAMATE;
TERT BUTYL [5 [[4 [(6 METHOXYQUINOLIN 8 YL)AMINO]PENTYL]AMINO] 4 [[[4 [(6 METHOXYQUINOLIN 8 YL)AMINO]PENTYL]CARBAMOYL]AMINO] 5 OXOPENTYL]CARBAMATE;
TERT BUTYL [6 [[4 [(2 TERT BUTYL 6 METHOXYQUINOLIN 8 YL)AMINO]PENTYL]AMINO] 5 [[[4 [(21 TERT BUTYL 6 METHOXYQUINOLIN 8 YL)AMINO]PENTYL]CARBAMOYL]AMINO] 6 OXOHEXYL] CARBAMATE;
TERT BUTYL [6 [[4 [(6 METHOXYQUINOLIN 8 YL)AMINO]PENTYL]AMINO] 5 [[[4 [(6 METHOXYQUINOLIN 8 YL)AMINO]PENTYL]CARBAMOYL]AMINO] 6 OXOHEXYL]CARBAMATE;
UNCLASSIFIED DRUG;
UNINDEXED DRUG;
ANIMAL EXPERIMENT;
ANIMAL MODEL;
ANTIBACTERIAL ACTIVITY;
ANTIFUNGAL ACTIVITY;
ANTIMICROBIAL ACTIVITY;
ANTIPROTOZOAL ACTIVITY;
ARTICLE;
CONTROLLED STUDY;
DRUG CYTOTOXICITY;
DRUG STRUCTURE;
DRUG SYNTHESIS;
GLUCOSE 6 PHOSPHATE DEHYDROGENASE DEFICIENCY;
IC 50;
IN VITRO STUDY;
IN VIVO STUDY;
LEISHMANIA DONOVANI;
MINIMUM INHIBITORY CONCENTRATION;
MOUSE;
NONHUMAN;
PLASMODIUM BERGHEI;
PLASMODIUM BERGHEI INFECTION;
PLASMODIUM FALCIPARUM;
SCHIZONT;
AMINOQUINOLINES;
ANIMALS;
ANTI-INFECTIVE AGENTS;
ANTIPROTOZOAL AGENTS;
HEMEPROTEINS;
HUMANS;
METHEMOGLOBIN;
FUNGI;
LEISHMANIA DONOVANI;
PLASMODIUM BERGHEI;
PLASMODIUM FALCIPARUM;
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EID: 78650724579
PISSN: 09680896
EISSN: None
Source Type: Journal
DOI: 10.1016/j.bmc.2010.11.036 Document Type: Article |
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Times cited : (52)
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References (41)
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