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Volumn 13, Issue 8, 2013, Pages 1178-1187

Soy and its isoflavones: The truth behind the science in breast cancer

Author keywords

Estrogen metabolism; Isoflavones; Mammographic density; Menstrual cycle; Phytoestrogens; Tumors

Indexed keywords

DAIDZIN; EQUOL; ESTRADIOL; ESTROGEN; GENISTIN; GLYCITEIN; ISOFLAVONE DERIVATIVE; PHYTOESTROGEN; PROGESTERONE RECEPTOR; PROTEIN PS2; SOY ISOFLAVONE DERIVATIVE; SOYBEAN PROTEIN; TAMOXIFEN; UNCLASSIFIED DRUG;

EID: 84888267104     PISSN: 18715206     EISSN: 18755992     Source Type: Journal    
DOI: 10.2174/18715206113139990320     Document Type: Article
Times cited : (56)

References (107)
  • 3
    • 0028942008 scopus 로고
    • Breast cancer incidence in Asian migrants to the United States and their descendants
    • Stanford, J.L., Herrinton, L.J., Schwartz, S.M., Weiss, N.S. Breast cancer incidence in Asian migrants to the United States and their descendants. Epidemiology, 1995, 6, 181-183.
    • (1995) Epidemiology , vol.6 , pp. 181-183
    • Stanford, J.L.1    Herrinton, L.J.2    Schwartz, S.M.3    Weiss, N.S.4
  • 4
    • 66849115652 scopus 로고    scopus 로고
    • Adolescent and adult soy food intake and breast cancer risk: Results from the Shanghai Women's Health Study
    • Lee, S.A., Shu, X.O., Li, H., Yang, G., Cai, H., Wen, W., Ji, B.T., Gao, J., Gao, Y.T., Zheng, W., Adolescent and adult soy food intake and breast cancer risk: results from the Shanghai Women's Health Study. Am. J. Clin. Nutr., 2009, 89, 1920-1926.
    • (2009) Am. J. Clin. Nutr , vol.89 , pp. 1920-1926
    • Lee, S.A.1    Shu, X.O.2    Li, H.3    Yang, G.4    Cai, H.5    Wen, W.6    Ji, B.T.7    Gao, J.8    Gao, Y.T.9    Zheng, W.10
  • 5
    • 77950464161 scopus 로고    scopus 로고
    • A vegetable-fruit-soy dietary pattern protects against breast cancer among postmenopausal Singapore Chinese women
    • Butler, L.M., Wu, A.H., Wang, R., Koh, W.P., Yuan, J.M., Yu, M.C. A vegetable-fruit-soy dietary pattern protects against breast cancer among postmenopausal Singapore Chinese women. Am. J. Clin. Nutr., 2010, 91, 1013-1019.
    • (2010) Am. J. Clin. Nutr , vol.91 , pp. 1013-1019
    • Butler, L.M.1    Wu, A.H.2    Wang, R.3    Koh, W.P.4    Yuan, J.M.5    Yu, M.C.6
  • 7
    • 62149124861 scopus 로고    scopus 로고
    • Urinary isoflavones and their metabolites validate the dietary isoflavone intakes in US adults
    • Chun, O.K., Chung, S.J., Song, W.O. Urinary isoflavones and their metabolites validate the dietary isoflavone intakes in US adults. J. Am. Diet. Assoc., 2009, 109, 245-54.
    • (2009) J. Am. Diet. Assoc , vol.109 , pp. 245-254
    • Chun, O.K.1    Chung, S.J.2    Song, W.O.3
  • 8
    • 0030976331 scopus 로고    scopus 로고
    • Phyto-oestrogens and Western diseases
    • Adlercreutz, H., Mazur, W. Phyto-oestrogens and Western diseases. Annals of medicine, 1997, 29, 95-120.
    • (1997) Annals of Medicine , vol.29 , pp. 95-120
    • Adlercreutz, H.1    Mazur, W.2
  • 9
    • 33749160353 scopus 로고    scopus 로고
    • Estimated Asian adult soy protein and isoflavone intakes
    • Messina, M., Nagata, C., Wu, A.H. Estimated Asian adult soy protein and isoflavone intakes. Nutr. Cancer, 2006, 55, 1-12.
    • (2006) Nutr. Cancer , vol.55 , pp. 1-12
    • Messina, M.1    Nagata, C.2    Wu, A.H.3
  • 10
    • 0029776049 scopus 로고    scopus 로고
    • Phytoestrogen content of foods--a compendium of literature values
    • Reinli, K., Block, G. Phytoestrogen content of foods--a compendium of literature values. Nutr. Cancer, 1996, 26, 123-48.
    • (1996) Nutr. Cancer , vol.26 , pp. 123-148
    • Reinli, K.1    Block, G.2
  • 11
    • 0028849729 scopus 로고
    • Phytoestrogens: Epidemiology and a possible role in cancer protection
    • Adlercreutz, H. Phytoestrogens: Epidemiology and a possible role in cancer protection. Environ. Health Perspect., 1995, 103 Suppl 7, 103-112.
    • (1995) Environ. Health Perspect , vol.103 , Issue.SUPPL. 7 , pp. 103-112
    • Adlercreutz, H.1
  • 12
    • 33750205003 scopus 로고    scopus 로고
    • Isoflavone metabolites and their in vitro dual functions: They can act as an estrogenic agonist or antagonist depending on the estrogen concentration
    • Hwang, C.S., Kwak, H.S., Lim, H.J., Lee, S.H., Kang, Y.S., Choe, T.B., Hur, H.G., Han, K.O. Isoflavone metabolites and their in vitro dual functions: They can act as an estrogenic agonist or antagonist depending on the estrogen concentration. J. Steroid Biochem. Mol. Biol., 2006, 101, 246-253.
    • (2006) J. Steroid Biochem. Mol. Biol , vol.101 , pp. 246-253
    • Hwang, C.S.1    Kwak, H.S.2    Lim, H.J.3    Lee, S.H.4    Kang, Y.S.5    Choe, T.B.6    Hur, H.G.7    Han, K.O.8
  • 13
    • 31544474853 scopus 로고    scopus 로고
    • Dietary soy isoflavones inhibit estrogen effects in the postmenopausal breast
    • Wood, C.E., Register, T.C., Franke, A.A., Anthony, M.S., Cline, J.M. Dietary soy isoflavones inhibit estrogen effects in the postmenopausal breast. Cancer Res., 2006, 66, 1241-1249.
    • (2006) Cancer Res , vol.66 , pp. 1241-1249
    • Wood, C.E.1    Register, T.C.2    Franke, A.A.3    Anthony, M.S.4    Cline, J.M.5
  • 14
    • 45849115105 scopus 로고    scopus 로고
    • The key importance of soy isoflavone bioavailability to understanding health benefits
    • Larkin, T., Price, W.E., Astheimer, L. The key importance of soy isoflavone bioavailability to understanding health benefits. Crit. Rev. Food Sci. Nutr., 2008, 48, 538-552.
    • (2008) Crit. Rev. Food Sci. Nutr , vol.48 , pp. 538-552
    • Larkin, T.1    Price, W.E.2    Astheimer, L.3
  • 16
    • 0037383299 scopus 로고    scopus 로고
    • Bioavailability, disposition, and dose-response effects of soy isoflavones when consumed by healthy women at physiologically typical dietary intakes
    • Setchell, K.D., Brown, N.M., Desai, P.B., Zimmer-Nechimias, L., Wolfe, B., Jakate, A.S., Creutzinger, V., Heubi, J.E., Bioavailability, disposition, and dose-response effects of soy isoflavones when consumed by healthy women at physiologically typical dietary intakes. J. Nutr., 2003, 133, 1027-1035.
    • (2003) J. Nutr , vol.133 , pp. 1027-1035
    • Setchell, K.D.1    Brown, N.M.2    Desai, P.B.3    Zimmer-Nechimias, L.4    Wolfe, B.5    Jakate, A.S.6    Creutzinger, V.7    Heubi, J.E.8
  • 17
    • 0037371414 scopus 로고    scopus 로고
    • Metabolism of flavonoids via enteric recycling: Role of intestinal disposition
    • Chen, J., Lin, H., Hu, M. Metabolism of flavonoids via enteric recycling: role of intestinal disposition. J Pharmacol. Exp. Ther., 2003, 304, 1228-1235.
    • (2003) J Pharmacol. Exp. Ther , vol.304 , pp. 1228-1235
    • Chen, J.1    Lin, H.2    Hu, M.3
  • 18
    • 0029146781 scopus 로고
    • Bioavailability of soybean isoflavones depends upon gut microflora in women
    • Xu, X., Harris, K.S., Wang, H.J., Murphy, P.A., Hendrich, S., Bioavailability of soybean isoflavones depends upon gut microflora in women. J. Nutr., 1995, 125, 2307-2315.
    • (1995) J. Nutr , vol.125 , pp. 2307-2315
    • Xu, X.1    Harris, K.S.2    Wang, H.J.3    Murphy, P.A.4    Hendrich, S.5
  • 19
    • 0031936764 scopus 로고    scopus 로고
    • HPLC analysis of isoflavonoids and other phenolic agents from foods and from human fluids
    • Franke, A. A., Custer, L. J., Wang, W., Shi, C. Y., HPLC analysis of isoflavonoids and other phenolic agents from foods and from human fluids. Proc. Soc. Exp. Biol. Med., 1998, 217, 263-73.
    • (1998) Proc. Soc. Exp. Biol. Med , vol.217 , pp. 263-273
    • Franke, A.A.1    Custer, L.J.2    Wang, W.3    Shi, C.Y.4
  • 20
    • 0036712527 scopus 로고    scopus 로고
    • Hydrolysis of isoflavone glycosides to aglycones by beta-glycosidase does not alter plasma and urine isoflavone pharmacokinetics in postmenopausal women
    • Richelle, M., Pridmore-Merten, S., Bodenstab, S., Enslen, M., Offord, E. A. Hydrolysis of isoflavone glycosides to aglycones by beta-glycosidase does not alter plasma and urine isoflavone pharmacokinetics in postmenopausal women. J. Nutr., 2002, 132, 2587-92.
    • (2002) J. Nutr , vol.132 , pp. 2587-2592
    • Richelle, M.1    Pridmore-Merten, S.2    Bodenstab, S.3    Enslen, M.4    Offord, E.A.5
  • 21
    • 0033464522 scopus 로고    scopus 로고
    • The role of intestinal bacteria in the causation and prevention of cancer: Modulation by diet and probiotics
    • Parodi, P. The role of intestinal bacteria in the causation and prevention of cancer: modulation by diet and probiotics. Aust J Dairy Technol, 1999, 54, 103-121.
    • (1999) Aust J Dairy Technol , vol.54 , pp. 103-121
    • Parodi, P.1
  • 22
    • 84865146287 scopus 로고    scopus 로고
    • Effects of estrogen and estrus cycle on pharmacokinetics, absorption, and disposition of genistein in female Sprague-Dawley rats
    • Kulkarni, K.H., Yang, Z., Niu, T., Hu, M., Effects of estrogen and estrus cycle on pharmacokinetics, absorption, and disposition of genistein in female Sprague-Dawley rats. J. Agric. Food Chem., 2012, 60, 7949-7956.
    • (2012) J. Agric. Food Chem , vol.60 , pp. 7949-7956
    • Kulkarni, K.H.1    Yang, Z.2    Niu, T.3    Hu, M.4
  • 23
    • 0031039888 scopus 로고    scopus 로고
    • Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta
    • Kuiper, G.G., Carlsson, B., Grandien, K., Enmark, E., Häggblad, J., Nilsson, S., Gustafsson, J.A. Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta. Endocrinology, 1997, 138, 863-870.
    • (1997) Endocrinology , vol.138 , pp. 863-870
    • Kuiper, G.G.1    Carlsson, B.2    Grandien, K.3    Enmark, E.4    Häggblad, J.5    Nilsson, S.6    Gustafsson, J.A.7
  • 25
    • 0346849610 scopus 로고    scopus 로고
    • Phytoestrogens modulate binding response of estrogen receptors alpha and beta to the estrogen response element
    • Kostelac, D., Rechkemmer, G., Briviba, K. Phytoestrogens modulate binding response of estrogen receptors alpha and beta to the estrogen response element. J. Agric. Food Chem., 2003, 51, 7632-5.
    • (2003) J. Agric. Food Chem , vol.51 , pp. 7632-7635
    • Kostelac, D.1    Rechkemmer, G.2    Briviba, K.3
  • 27
    • 1642393243 scopus 로고    scopus 로고
    • Dietary soy containing phytoestrogens does not have detectable estrogenic effects on hepatic protein synthesis in postmenopausal women
    • Teede, H.J., Dalais, F.S., McGrath, B.P. Dietary soy containing phytoestrogens does not have detectable estrogenic effects on hepatic protein synthesis in postmenopausal women. Am. J. Clin. Nutr., 2004, 79, 396-401.
    • (2004) Am. J. Clin. Nutr , vol.79 , pp. 396-401
    • Teede, H.J.1    Dalais, F.S.2    McGrath, B.P.3
  • 28
    • 33748988463 scopus 로고    scopus 로고
    • Addressing the soy and breast cancer relationship: Review, commentary, and workshop proceedings
    • Messina, M., McCaskill-Stevens, W., Lampe, J. W., Addressing the soy and breast cancer relationship: Review, commentary, and workshop proceedings. J. Natl. Cancer Inst., 2006, 98, 1275-1284.
    • (2006) J. Natl. Cancer Inst , vol.98 , pp. 1275-1284
    • Messina, M.1    McCaskill-Stevens, W.2    Lampe, J.W.3
  • 29
    • 0028136777 scopus 로고
    • Biological effects of a diet of soy protein rich in isoflavones on the menstrual cycle of premenopausal women
    • Cassidy, A., Bingham, S., Setchell, K. D. Biological effects of a diet of soy protein rich in isoflavones on the menstrual cycle of premenopausal women. Am. J. Clin. Nutr., 1994, 60, 333-340.
    • (1994) Am. J. Clin. Nutr , vol.60 , pp. 333-340
    • Cassidy, A.1    Bingham, S.2    Setchell, K.D.3
  • 30
    • 33846305324 scopus 로고    scopus 로고
    • Effects of soya consumption for one month on steroid hormones in premenopausal women: Implications for breast cancer risk reduction. Cancer Epidemiol
    • Lu, L.J., Anderson, K.E., Grady, J. J., Nagamani, M. Effects of soya consumption for one month on steroid hormones in premenopausal women: implications for breast cancer risk reduction. Cancer Epidemiol. Biomarkers Prev., 1996, 5, 63-70.
    • (1996) Biomarkers Prev , vol.5 , pp. 63-70
    • Lu, L.J.1    Anderson, K.E.2    Grady, J.J.3    Nagamani, M.4
  • 32
    • 67349280310 scopus 로고    scopus 로고
    • Soy, phytoestrogens and metabolism: A review
    • Cederroth, C.R., Nef, S. Soy, phytoestrogens and metabolism: A review. Mol Cell Endocrinol, 2009, 304, 30-42.
    • (2009) Mol Cell Endocrinol , vol.304 , pp. 30-42
    • Cederroth, C.R.1    Nef, S.2
  • 33
    • 84888244909 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention, Available at, (Accessed June 12, 2012)
    • Centers for Disease Control and Prevention. Breast Cancer: Risk Factors. Available at: http://www.cdc.gov/cancer/breast/basic_info/risk_factors.htm (Accessed June 12, 2012)
    • Breast Cancer: Risk Factors
  • 34
    • 0242457714 scopus 로고    scopus 로고
    • Sources of estrogen and their importance
    • Simpson, E.R. Sources of estrogen and their importance. J. Steroid Biochem. Mol. Biol., 2003, 86, 225-230.
    • (2003) J. Steroid Biochem. Mol. Biol , vol.86 , pp. 225-230
    • Simpson, E.R.1
  • 35
    • 0029872530 scopus 로고    scopus 로고
    • Concentrations of estrone, estradiol, and estrone sulfate and evaluation of sulfatase and aromatase activities in pre- and postmenopausal breast cancer patients
    • Pasqualini, J. R., Chetrite, G., Blacker, C., Feinstein, M. C., Delalonde, L., Talbi, M., Maloche, C. Concentrations of estrone, estradiol, and estrone sulfate and evaluation of sulfatase and aromatase activities in pre- and postmenopausal breast cancer patients. J. Clin. Endocrinol. Metab., 1996, 81, 1460-1464.
    • (1996) J. Clin. Endocrinol. Metab , vol.81 , pp. 1460-1464
    • Pasqualini, J.R.1    Chetrite, G.2    Blacker, C.3    Feinstein, M.C.4    Delalonde, L.5    Talbi, M.6    Maloche, C.7
  • 36
    • 0025461598 scopus 로고
    • Serum hormone levels in pre-menopausal Chinese women in Shanghai and white women in Los Angeles: Results from two breast cancer casecontrol studies
    • Bernstein, L., Yuan, J.M., Ross, R.K., Pike, M.C., Hanisch, R., Lobo, R., Stanczyk, F., Gao, Y.T., Henderson, B.E. Serum hormone levels in pre-menopausal Chinese women in Shanghai and white women in Los Angeles: results from two breast cancer casecontrol studies. Cancer Causes Control, 1990, 1, 51-58.
    • (1990) Cancer Causes Control , vol.1 , pp. 51-58
    • Bernstein, L.1    Yuan, J.M.2    Ross, R.K.3    Pike, M.C.4    Hanisch, R.5    Lobo, R.6    Stanczyk, F.7    Gao, Y.T.8    Henderson, B.E.9
  • 37
    • 0035800440 scopus 로고    scopus 로고
    • Population-based case-control study of soyfood intake and breast cancer risk in Shanghai
    • Dai, Q., Shu, X.O., Jin, F., Potter, J.D., Kushi, L.H., Teas, J., Gao, Y.T., Zheng, W. Population-based case-control study of soyfood intake and breast cancer risk in Shanghai. Br. J. Cancer, 2001, 85, 372-378.
    • (2001) Br. J. Cancer , vol.85 , pp. 372-378
    • Dai, Q.1    Shu, X.O.2    Jin, F.3    Potter, J.D.4    Kushi, L.H.5    Teas, J.6    Gao, Y.T.7    Zheng, W.8
  • 38
    • 75649105769 scopus 로고    scopus 로고
    • Soy product and isoflavone intake and breast cancer risk defined by hormone receptor status
    • Zhang, C., Ho, S. C., Lin, F., Cheng, S., Fu, J., Chen, Y. Soy product and isoflavone intake and breast cancer risk defined by hormone receptor status. Cancer Sci., 2010, 101, 501-7.
    • (2010) Cancer Sci , vol.101 , pp. 501-507
    • Zhang, C.1    Ho, S.C.2    Lin, F.3    Cheng, S.4    Fu, J.5    Chen, Y.6
  • 39
    • 38049074972 scopus 로고    scopus 로고
    • Epidemiology of soy exposures and breast cancer risk
    • Wu, A.H., Yu, M.C., Tseng, C.C., Pike, M.C. Epidemiology of soy exposures and breast cancer risk. Br. J. Cancer, 2008, 98, 9-14.
    • (2008) Br. J. Cancer , vol.98 , pp. 9-14
    • Wu, A.H.1    Yu, M.C.2    Tseng, C.C.3    Pike, M.C.4
  • 40
    • 0034903603 scopus 로고    scopus 로고
    • Assessing phytoestrogen exposure via a foodfrequency questionnaire
    • Horn-Ross, P. L. Assessing phytoestrogen exposure via a foodfrequency questionnaire. Cancer Causes Control, 2001, 12, 477-478.
    • (2001) Cancer Causes Control , vol.12 , pp. 477-478
    • Horn-Ross, P.L.1
  • 43
    • 0036714766 scopus 로고    scopus 로고
    • Adolescent and adult soy intake and risk of breast cancer in Asian- Americans
    • Wu, A.H., Wan, P., Hankin, J., Tseng, C.C., Yu, M.C., Pike, M.C. Adolescent and adult soy intake and risk of breast cancer in Asian- Americans. Carcinogenesis, 2002, 23, 1491-1496.
    • (2002) Carcinogenesis , vol.23 , pp. 1491-1496
    • Wu, A.H.1    Wan, P.2    Hankin, J.3    Tseng, C.C.4    Yu, M.C.5    Pike, M.C.6
  • 44
    • 43249085452 scopus 로고    scopus 로고
    • The role of early life genistein exposures in modifying breast cancer risk
    • Warri, A., Saarinen, N.M., Makela, S., Hilakivi-Clarke, L. The role of early life genistein exposures in modifying breast cancer risk. Br. J. Cancer, 2008, 98, 1485-1493.
    • (2008) Br. J. Cancer , vol.98 , pp. 1485-1493
    • Warri, A.1    Saarinen, N.M.2    Makela, S.3    Hilakivi-Clarke, L.4
  • 45
    • 34547558889 scopus 로고    scopus 로고
    • Nutritional modulation of terminal end buds: Its relevance to breast cancer prevention
    • Hilakivi-Clarke, L. Nutritional modulation of terminal end buds: Its relevance to breast cancer prevention. Curr. Cancer Drug Targets, 2007, 7, 465-74.
    • (2007) Curr. Cancer Drug Targets , vol.7 , pp. 465-474
    • Hilakivi-Clarke, L.1
  • 46
  • 48
    • 0030827132 scopus 로고    scopus 로고
    • Mammographic density in women on postmenopausal hormone replacement therapy
    • discussion 673-4
    • Leung, W., Goldberg, F., Zee, B., Sterns, E. Mammographic density in women on postmenopausal hormone replacement therapy. Surgery, 1997, 122, 669-73; discussion 673-4.
    • (1997) Surgery , vol.122 , pp. 669-673
    • Leung, W.1    Goldberg, F.2    Zee, B.3    Sterns, E.4
  • 49
    • 0346218106 scopus 로고    scopus 로고
    • Quantitative assessment of mammographic breast density: Relationship with breast cancer risk
    • Harvey, J.A., Bovbjerg, V.E. Quantitative assessment of mammographic breast density: Relationship with breast cancer risk. Radiology, 2004, 230, 29-41.
    • (2004) Radiology , vol.230 , pp. 29-41
    • Harvey, J.A.1    Bovbjerg, V.E.2
  • 51
    • 7944234372 scopus 로고    scopus 로고
    • A 2-year soy intervention in premenopausal women does not change mammographic densities
    • Maskarinec, G., Takata, Y., Franke, A.A., Williams, A.E., Murphy, S.P. A 2-year soy intervention in premenopausal women does not change mammographic densities. J. Nutr., 2004, 134, 3089-94.
    • (2004) J. Nutr , vol.134 , pp. 3089-3094
    • Maskarinec, G.1    Takata, Y.2    Franke, A.A.3    Williams, A.E.4    Murphy, S.P.5
  • 52
    • 77953593007 scopus 로고    scopus 로고
    • Long-term endometrial and breast safety of a specific, standardized soy extract
    • Palacios, S., Pornel, B., Vazquez, F., Aubert, L., Chantre, P., Mares, P. Long-term endometrial and breast safety of a specific, standardized soy extract. Climacteric, 2010, 13, 368-75.
    • (2010) Climacteric , vol.13 , pp. 368-375
    • Palacios, S.1    Pornel, B.2    Vazquez, F.3    Aubert, L.4    Chantre, P.5    Mares, P.6
  • 53
    • 0038407920 scopus 로고    scopus 로고
    • Mammographic densities in a one-year isoflavone intervention
    • Maskarinec, G., Williams, A.E., Carlin, L. Mammographic densities in a one-year isoflavone intervention. Eur. J. Cancer Prev., 2003, 12, 165-169.
    • (2003) Eur. J. Cancer Prev , vol.12 , pp. 165-169
    • Maskarinec, G.1    Williams, A.E.2    Carlin, L.3
  • 56
    • 0033869533 scopus 로고    scopus 로고
    • Decreased ovarian hormones during a soya diet: Implications for breast cancer prevention
    • Lu, L. J., Anderson, K. E., Grady, J. J., Kohen, F., Nagamani, M. Decreased ovarian hormones during a soya diet: Implications for breast cancer prevention. Cancer Res., 2000, 60, 4112-21.
    • (2000) Cancer Res , vol.60 , pp. 4112-4121
    • Lu, L.J.1    Anderson, K.E.2    Grady, J.J.3    Kohen, F.4    Nagamani, M.5
  • 57
    • 0036121473 scopus 로고    scopus 로고
    • Acute and chronic effects of genistein, tyrphostin and lavendustin A on steroid synthesis in luteinized human granulosa cells
    • Whitehead, S. A., Cross, J. E., Burden, C., Lacey, M. Acute and chronic effects of genistein, tyrphostin and lavendustin A on steroid synthesis in luteinized human granulosa cells. Hum. Reprod., 2002, 17, 589-94.
    • (2002) Hum. Reprod , vol.17 , pp. 589-594
    • Whitehead, S.A.1    Cross, J.E.2    Burden, C.3    Lacey, M.4
  • 58
    • 33750132434 scopus 로고    scopus 로고
    • Phytoestrogens and their low dose combinations inhibit mRNA expression and activity of aromatase in human granulosa-luteal cells
    • Rice, S., Mason, H. D., Whitehead, S. A. Phytoestrogens and their low dose combinations inhibit mRNA expression and activity of aromatase in human granulosa-luteal cells. J. Steroid Biochem. Mol. Biol., 2006, 101, 216-25.
    • (2006) J. Steroid Biochem. Mol. Biol , vol.101 , pp. 216-225
    • Rice, S.1    Mason, H.D.2    Whitehead, S.A.3
  • 59
    • 79955608460 scopus 로고    scopus 로고
    • The National Cancer Institute, Available at, (Accessed May 21, 2012)
    • The National Cancer Institute. Aromatase Inhibitors. Available at: http://www.cancer.gov/cancertopics/treatment/aromataseinhibitors/Page4 (Accessed May 21, 2012).
    • Aromatase Inhibitors
  • 60
    • 0019447387 scopus 로고
    • Morphological evaluation of cell turnover in relation to the menstrual cycle in the resting human breast
    • Ferguson, D.J., Anderson, T.J. Morphological evaluation of cell turnover in relation to the menstrual cycle in the resting human breast. Br. J. Cancer, 1981, 44, 177-181.
    • (1981) Br. J. Cancer , vol.44 , pp. 177-181
    • Ferguson, D.J.1    Anderson, T.J.2
  • 61
    • 0020953749 scopus 로고
    • Individual variation in gonadotrophin and steroid concentrations and in the lengths of the follicular and luteal phases in women with regular menstrual cycles
    • Lenton, E.A., Lawrence, G.F., Coleman, R. A., Cooke, I.D. Individual variation in gonadotrophin and steroid concentrations and in the lengths of the follicular and luteal phases in women with regular menstrual cycles. Clin. Reprod. Fertil., 1983, 2, 143-150.
    • (1983) Clin. Reprod. Fertil , vol.2 , pp. 143-150
    • Lenton, E.A.1    Lawrence, G.F.2    Coleman, R.A.3    Cooke, I.D.4
  • 62
    • 0020671721 scopus 로고
    • Retrospective assessment of menstrual cycle length in patients with breast cancer, in patients with benign breast disease, and in women without breast disease
    • Olsson, H., Landin-Olsson, M., Gullberg, B. Retrospective assessment of menstrual cycle length in patients with breast cancer, in patients with benign breast disease, and in women without breast disease. J. Natl. Cancer Inst., 1983, 70, 17-20.
    • (1983) J. Natl. Cancer Inst , vol.70 , pp. 17-20
    • Olsson, H.1    Landin-Olsson, M.2    Gullberg, B.3
  • 63
    • 0032477289 scopus 로고    scopus 로고
    • Effect of soymilk consumption on serum estrogen concentrations in premenopausal Japanese women
    • Nagata, C., Takatsuka, N., Inaba, S., Kawakami, N., Shimizu, H. Effect of soymilk consumption on serum estrogen concentrations in premenopausal Japanese women. J. Natl. Cancer Inst., 1998, 90, 1830-1835.
    • (1998) J. Natl. Cancer Inst , vol.90 , pp. 1830-1835
    • Nagata, C.1    Takatsuka, N.2    Inaba, S.3    Kawakami, N.4    Shimizu, H.5
  • 65
    • 0028856746 scopus 로고
    • Biological effects of isoflavones in young women: Importance of the chemical composition of soyabean products
    • Cassidy, A., Bingham, S., Setchell, K., Biological effects of isoflavones in young women: Importance of the chemical composition of soyabean products. Br. J. Nutr., 1995, 74, 587-601.
    • (1995) Br. J. Nutr , vol.74 , pp. 587-601
    • Cassidy, A.1    Bingham, S.2    Setchell, K.3
  • 68
    • 0031848636 scopus 로고    scopus 로고
    • Functional role of estrogen metabolism in target cells: Review and perspectives
    • Zhu, B.T., Conney, A.H., Functional role of estrogen metabolism in target cells: Review and perspectives. Carcinogenesis, 1998, 19, 1-27.
    • (1998) Carcinogenesis , vol.19 , pp. 1-27
    • Zhu, B.T.1    Conney, A.H.2
  • 69
    • 0029890377 scopus 로고    scopus 로고
    • Molecular mechanisms of estrogen carcinogenesis
    • Yager, J.D., Liehr, J.G. Molecular mechanisms of estrogen carcinogenesis. Annu. Rev. Pharmacol. Toxicol., 1996, 36, 203-232.
    • (1996) Annu. Rev. Pharmacol. Toxicol , vol.36 , pp. 203-232
    • Yager, J.D.1    Liehr, J.G.2
  • 72
  • 74
    • 0033847348 scopus 로고    scopus 로고
    • Soy consumption alters endogenous estrogen metabolism in postmenopausal women
    • Xu, X., Duncan, A.M., Wangen, K.E., Kurzer, M.S. Soy consumption alters endogenous estrogen metabolism in postmenopausal women. Cancer Epidemiol. Biomarkers Prev., 2000, 9, 781-786.
    • (2000) Cancer Epidemiol. Biomarkers Prev , vol.9 , pp. 781-786
    • Xu, X.1    Duncan, A.M.2    Wangen, K.E.3    Kurzer, M.S.4
  • 75
    • 0032407033 scopus 로고    scopus 로고
    • Effects of soy isoflavones on estrogen and phytoestrogen metabolism in premenopausal women
    • Xu, X., Duncan, A.M., Merz, B.E., Kurzer, M.S. Effects of soy isoflavones on estrogen and phytoestrogen metabolism in premenopausal women. Cancer Epidemiol. Biomarkers Prev., 1998, 7, 1101-1108.
    • (1998) Cancer Epidemiol. Biomarkers Prev , vol.7 , pp. 1101-1108
    • Xu, X.1    Duncan, A.M.2    Merz, B.E.3    Kurzer, M.S.4
  • 86
    • 70350217376 scopus 로고    scopus 로고
    • Soy isoflavones and risk of cancer recurrence in a cohort of breast cancer survivors: The life after cancer epidemiology study
    • Guha, N., Kwan, M.L., Quesenberry, C.P., Jr., Weltzien, E.K., Castillo, A.L., Caan, B.J. Soy isoflavones and risk of cancer recurrence in a cohort of breast cancer survivors: The life after cancer epidemiology study. Breast Cancer Res. Treat., 2009, 118, 395-405.
    • (2009) Breast Cancer Res. Treat , vol.118 , pp. 395-405
    • Guha, N.1    Kwan, M.L.2    Quesenberry Jr., C.P.3    Weltzien, E.K.4    Castillo, A.L.5    Caan, B.J.6
  • 89
    • 17844379469 scopus 로고    scopus 로고
    • One year soy protein supplementation has positive effects on bone formation markers but not bone density in postmenopausal women
    • Arjmandi, B. H., Lucas, E. A., Khalil, D. A., Devareddy, L., Smith, B. J., McDonald, J., Arquitt, A. B., Payton, M. E., Mason, C. One year soy protein supplementation has positive effects on bone formation markers but not bone density in postmenopausal women. Nutr. J., 2005, 4, 8.
    • (2005) Nutr. J , vol.4 , pp. 8
    • Arjmandi, B.H.1    Lucas, E.A.2    Khalil, D.A.3    Devareddy, L.4    Smith, B.J.5    McDonald, J.6    Arquitt, A.B.7    Payton, M.E.8    Mason, C.9
  • 90
    • 0028216956 scopus 로고
    • Soy intake and cancer risk: A review of the in vitro and in vivo data
    • Messina, M.J., Persky, V., Setchell, K.D., Barnes, S. Soy intake and cancer risk: A review of the in vitro and in vivo data. Nutr Cancer, 1994, 21, 113-131.
    • (1994) Nutr Cancer , vol.21 , pp. 113-131
    • Messina, M.J.1    Persky, V.2    Setchell, K.D.3    Barnes, S.4
  • 91
    • 78650992290 scopus 로고    scopus 로고
    • Soy isoflavones consumption and risk of breast cancer incidence or recurrence: A meta-analysis of prospective studies
    • Dong, J.Y., Qin, L.Q. Soy isoflavones consumption and risk of breast cancer incidence or recurrence: A meta-analysis of prospective studies. Breast Cancer Res. Treat., 2011, 125, 315-23.
    • (2011) Breast Cancer Res. Treat , vol.125 , pp. 315-323
    • Dong, J.Y.1    Qin, L.Q.2
  • 93
    • 66749171779 scopus 로고    scopus 로고
    • Effects of soy protein and isoflavones on circulating hormone concentrations in pre- and post-menopausal women: A systematic review and meta-analysis
    • Hooper, L., Ryder, J.J., Kurzer, M.S., Lampe, J.W., Messina, M.J., Phipps, W.R., Cassidy, A. Effects of soy protein and isoflavones on circulating hormone concentrations in pre- and post-menopausal women: A systematic review and meta-analysis. Human Reprod. Update, 2009, 15, 423-440.
    • (2009) Human Reprod. Update , vol.15 , pp. 423-440
    • Hooper, L.1    Ryder, J.J.2    Kurzer, M.S.3    Lampe, J.W.4    Messina, M.J.5    Phipps, W.R.6    Cassidy, A.7
  • 95
    • 33747585809 scopus 로고    scopus 로고
    • Effects of high-dose soy isoflavones and equol on reproductive tissues in female cynomolgus monkeys
    • Wood, C.E., Appt, S.E., Clarkson, T.B., Franke, A.A., Lees, C.J., Doerge, D.R., Cline, J.M. Effects of high-dose soy isoflavones and equol on reproductive tissues in female cynomolgus monkeys. Biol. Reprod., 2006, 75, 477-486.
    • (2006) Biol. Reprod , vol.75 , pp. 477-486
    • Wood, C.E.1    Appt, S.E.2    Clarkson, T.B.3    Franke, A.A.4    Lees, C.J.5    Doerge, D.R.6    Cline, J.M.7
  • 96
    • 50249148343 scopus 로고    scopus 로고
    • Estrogen effects on epithelial proliferation and benign proliferative lesions in the postmenopausal primate mammary gland
    • Wood, C.E., Hester, J.M., Appt, S.E., Geisinger, K.R., Cline, J.M. Estrogen effects on epithelial proliferation and benign proliferative lesions in the postmenopausal primate mammary gland. Lab Ivest., 2008, 88, 938-948.
    • (2008) Lab Ivest , vol.88 , pp. 938-948
    • Wood, C.E.1    Hester, J.M.2    Appt, S.E.3    Geisinger, K.R.4    Cline, J.M.5
  • 97
    • 0035394121 scopus 로고    scopus 로고
    • Soy diets containing varying amounts of genistein stimulate growth of estrogen-dependent (MCF-7) tumors in a dose-dependent manner
    • Allred, C.D., Allred, K.F., Ju, Y.H., Virant, S.M., Helferich, W.G., Soy diets containing varying amounts of genistein stimulate growth of estrogen-dependent (MCF-7) tumors in a dose-dependent manner. Cancer Res., 2001, 61, 5045-5450.
    • (2001) Cancer Res , vol.61 , pp. 5045-5450
    • Allred, C.D.1    Allred, K.F.2    Ju, Y.H.3    Virant, S.M.4    Helferich, W.G.5
  • 102
    • 3242693966 scopus 로고    scopus 로고
    • Breast and uterine effects of soy isoflavones and conjugated equine estrogens in postmenopausal female monkeys
    • Wood, C.E., Register, T.C., Anthony, M.S., Kock, N.D., Cline, J.M. Breast and uterine effects of soy isoflavones and conjugated equine estrogens in postmenopausal female monkeys. J. Clin. Endocrinol. Metab., 2004, 89, 3462-3468.
    • (2004) J. Clin. Endocrinol. Metab , vol.89 , pp. 3462-3468
    • Wood, C.E.1    Register, T.C.2    Anthony, M.S.3    Kock, N.D.4    Cline, J.M.5
  • 104
    • 49949116697 scopus 로고    scopus 로고
    • The combination of genistin and ipriflavone prevents mammary tumorigenesis and modulates lipid profile
    • Hooshmand, S., Khalil, D.A., Murillo, G., Singletary, K., Kamath, S.K., Arjmandi, B.H., The combination of genistin and ipriflavone prevents mammary tumorigenesis and modulates lipid profile. Clin. Nutr., 2008, 27, 643-648.
    • (2008) Clin. Nutr , vol.27 , pp. 643-648
    • Hooshmand, S.1    Khalil, D.A.2    Murillo, G.3    Singletary, K.4    Kamath, S.K.5    Arjmandi, B.H.6
  • 106
    • 80054953743 scopus 로고    scopus 로고
    • Soy isoflavone phase II metabolism differs between rodents and humans: Implications for the effect on breast cancer risk
    • Setchell, K.D., Brown, N.M., Zhao, X., Lindley, S.L., Heubi, J.E., King, E.C., Messina, M.J. Soy isoflavone phase II metabolism differs between rodents and humans: implications for the effect on breast cancer risk. Am. J. Clin. Nutr., 2011, 94, 1284-1294.
    • (2011) Am. J. Clin. Nutr , vol.94 , pp. 1284-1294
    • Setchell, K.D.1    Brown, N.M.2    Zhao, X.3    Lindley, S.L.4    Heubi, J.E.5    King, E.C.6    Messina, M.J.7
  • 107
    • 0037339004 scopus 로고    scopus 로고
    • Soy protein has a greater effect on bone in postmenopausal women not on hormone replacement therapy, as evidenced by reducing bone resorption and urinary calcium excretion
    • Arjmandi, B.H., Khalil, D.A., Smith, B.J., Lucas, E.A., Juma, S., Payton, M.E., Wild, R.A. Soy protein has a greater effect on bone in postmenopausal women not on hormone replacement therapy, as evidenced by reducing bone resorption and urinary calcium excretion. J. Clin. Endocrinol. Metab., 2003, 88, 1048-54.
    • (2003) J. Clin. Endocrinol. Metab , vol.88 , pp. 1048-1054
    • Arjmandi, B.H.1    Khalil, D.A.2    Smith, B.J.3    Lucas, E.A.4    Juma, S.5    Payton, M.E.6    Wild, R.A.7


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