Stability of transmembrane amyloid β-peptide and membrane integrity tested by molecular modeling of site-specific Aβ42 mutations

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Poojari, Chetan ^a   Strodel, Birgit ^a,b  

^a FORSCHUNGSZENTRUM JÜLICH   (Germany)

^b HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; MUTANT PROTEIN;

ARTICLE; BETA SHEET; CONTROLLED STUDY; GENE MUTATION; GENETIC POLYMORPHISM; LIPID BILAYER; LIPID MEMBRANE; MEMBRANE BIOLOGY; MEMBRANE DAMAGE; MEMBRANE INTEGRITY; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MODEL; NERVE CELL MEMBRANE; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN STABILITY; WILD TYPE;

ALZHEIMER DISEASE; AMINO ACID SUBSTITUTION; AMYLOID BETA-PEPTIDES; CELL MEMBRANE; HUMANS; LIPID BILAYERS; MODELS, MOLECULAR; MUTATION, MISSENSE; PEPTIDE FRAGMENTS; PROTEIN STABILITY;

EID: 84887897788     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0078399     Document Type: Article

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