-
1
-
-
0026597063
-
Alzheimer's disease: The amyloid cascade hypothesis
-
Hardy J.A., Higgins G.A. (1992) Alzheimer's disease: The amyloid cascade hypothesis. Science 256:184-185.
-
(1992)
Science
, vol.256
, pp. 184-185
-
-
Hardy, J.A.1
Higgins, G.A.2
-
2
-
-
0242668337
-
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
-
DOI 10.1126/science.1079469
-
Kayed R., Head E., Thompson J.L., McIntire T.M., Milton S.C., Cotman C.W., Glabe C.G. (2003) Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science 300:486-489. (Pubitemid 36444329)
-
(2003)
Science
, vol.300
, Issue.5618
, pp. 486-489
-
-
Kayed, R.1
Head, E.2
Thompson, J.L.3
McIntire, T.M.4
Milton, S.C.5
Cotman, C.W.6
Glabel, C.G.7
-
3
-
-
8744220663
-
Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases
-
DOI 10.1074/jbc.C400260200
-
Kayed R., Sokolov Y., Edmonds B., McIntire T.M., Milton S.C., Hall J.E., Glabe C.G. (2004) Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases. J Biol Chem 279:46363-46366. (Pubitemid 39518276)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.45
, pp. 46363-46366
-
-
Kayed, R.1
Sokolov, Y.2
Edmonds, B.3
McIntire, T.M.4
Milton, S.C.5
Hall, J.E.6
Glabe, C.G.7
-
4
-
-
57649217285
-
The role of amyloid precursor protein processing by BACE1, the β-secretase, in Alzheimer disease pathophysiology
-
Cole S.L., Vassar R. (2008) The role of amyloid precursor protein processing by BACE1, the β-secretase, in Alzheimer disease pathophysiology. J Biol Chem 283: 29621-29625.
-
(2008)
J Biol Chem
, vol.283
, pp. 29621-29625
-
-
Cole, S.L.1
Vassar, R.2
-
5
-
-
57649174625
-
Intramembrane proteolysis by γ-secretase
-
Steiner H., Fluhrer R., Haass C. (2008) Intramembrane proteolysis by γ-secretase. J Biol Chem 283:29627-29631.
-
(2008)
J Biol Chem
, vol.283
, pp. 29627-29631
-
-
Steiner, H.1
Fluhrer, R.2
Haass, C.3
-
6
-
-
40349102241
-
Active γ-secretase is localized to detergent-resistant membranes in human brain
-
DOI 10.1111/j.1742-4658.2008.06278.x
-
Hur J-Y, Welander H., Behbahani H., Aoki M, Frå nberg J, Winblad B, Frykman S, Tjernberg LO (2010) Active γ-secretase is localized to detergent-resistant membranes in human brain. FEBS J 275:1174-1187. (Pubitemid 351342213)
-
(2008)
FEBS Journal
, vol.275
, Issue.6
, pp. 1174-1187
-
-
Hur, J.-Y.1
Welander, H.2
Behbahani, H.3
Aoki, M.4
Franberg, J.5
Winblad, B.6
Frykman, S.7
Tjernberg, L.O.8
-
7
-
-
33746678668
-
Lipid asymmetry of the eukaryotic plasma membrane: Functions and related enzymes
-
DOI 10.1248/bpb.29.1542
-
Ikeda M., Kihara A., Igarashi Y. (2006) Lipid asymmetry of the eukaryotic plasma membrane: Functions and related enzymes. Biol Pharm Bull 29:1542-1546. (Pubitemid 44166348)
-
(2006)
Biological and Pharmaceutical Bulletin
, vol.29
, Issue.8
, pp. 1542-1546
-
-
Ikeda, M.1
Kihara, A.2
Igarashi, Y.3
-
8
-
-
0025876649
-
Static and dynamic lipid asymmetry in cell membranes
-
Devaux P.F. (1991) Static and dynamic lipid asymmetry in cell membranes. Biochemistry 30:1163-1173.
-
(1991)
Biochemistry
, vol.30
, pp. 1163-1173
-
-
Devaux, P.F.1
-
10
-
-
0028885854
-
GM1 ganglioside-bound amyloid β-protein (Aβ): A possible form of preamyloid in Alzheimer's disease
-
Yanagisawa K., Odaka A., Suzuki N., Ihara Y. (1995) GM1 ganglioside-bound amyloid β-protein (Aβ): A possible form of preamyloid in Alzheimer's disease. Nat Med 1:1062-1066.
-
(1995)
Nat Med
, vol.1
, pp. 1062-1066
-
-
Yanagisawa, K.1
Odaka, A.2
Suzuki, N.3
Ihara, Y.4
-
11
-
-
0035816709
-
Cholesterol-dependent formation of GM1 ganglioside-bound amyloid β-protein, an endogenous seed for Alzheimer amyloid
-
Kakio A., Nishimoto S-i, Yanagisawa K., Kozutsumi Y., Matsuzaki K. (2001) Cholesterol-dependent formation of GM1 ganglioside-bound amyloid β-protein, an endogenous seed for Alzheimer amyloid. J Biol Chem 276: 24985-24990.
-
(2001)
J Biol Chem
, vol.276
, pp. 24985-24990
-
-
Kakio, A.1
Nishimoto, S.-I.2
Yanagisawa, K.3
Kozutsumi, Y.4
Matsuzaki, K.5
-
12
-
-
0037062582
-
Interactions of amyloid β-protein with various gangliosides in raft-like membranes: Importance of GM1 ganglioside-bound form as an endogenous seed for Alzheimer amyloid
-
DOI 10.1021/bi0255874
-
Kakio A., Nishimoto S-i, Yanagisawa K., Kozutsumi Y., Matsuzaki K. (2002) Interactions of amyloid β-protein with various gangliosides in raft-like membranes: Importance of GM1 ganglioside-bound form as an endogenous seed for Alzheimer amyloid. Biochemistry 41: 7385-7390. (Pubitemid 34602456)
-
(2002)
Biochemistry
, vol.41
, Issue.23
, pp. 7385-7390
-
-
Kakio, A.1
Nishimoto, S.-I.2
Yanagisawa, K.3
Kozutsumi, Y.4
Matsuzaki, K.5
-
13
-
-
0033616779
-
Interactions of amyloid β-peptide (1-40) with ganglioside-containing membranes
-
Matsuzaki K., Horikiri C. (1999) Interactions of amyloid β-peptide (1-40) with ganglioside-containing membranes. Biochemistry 38:4137-4142.
-
(1999)
Biochemistry
, vol.38
, pp. 4137-4142
-
-
Matsuzaki, K.1
Horikiri, C.2
-
15
-
-
72649096531
-
Up-and-down topological mode of amyloid β-peptide lying on hydrophilic/hydrophobic interface of ganglioside clusters
-
Utsumi M., Yamaguchi Y., Sasakawa H., Yamamoto N., Yanagisawa K., Kato K. (2009) Up-and-down topological mode of amyloid β-peptide lying on hydrophilic/hydrophobic interface of ganglioside clusters. Glyconjugate J 26:999-1006.
-
(2009)
Glyconjugate J
, vol.26
, pp. 999-1006
-
-
Utsumi, M.1
Yamaguchi, Y.2
Sasakawa, H.3
Yamamoto, N.4
Yanagisawa, K.5
Kato, K.6
-
16
-
-
77649270452
-
NMR characterization of the interactions between lyso-GM1 aqueous micelles and amyloid β
-
Yagi-Utsumi M., Kameda T., Yamaguchi Y., Kato K. (2010) NMR characterization of the interactions between lyso-GM1 aqueous micelles and amyloid β. FEBS Lett 584:831-836.
-
(2010)
FEBS Lett
, vol.584
, pp. 831-836
-
-
Yagi-Utsumi, M.1
Kameda, T.2
Yamaguchi, Y.3
Kato, K.4
-
17
-
-
38349077350
-
A comparative molecular dynamics analysis of the amyloid β-peptide in a lipid bilayer
-
Lemkul J.A., Bevan D.R. (2008) A comparative molecular dynamics analysis of the amyloid β-peptide in a lipid bilayer. Arch Biochem Biophys 470:54-63.
-
(2008)
Arch Biochem Biophys
, vol.470
, pp. 54-63
-
-
Lemkul, J.A.1
Bevan, D.R.2
-
18
-
-
65549152828
-
Perturbation of membranes by the amyloid β-peptide - A molecular dynamics study
-
Lemkul J.A., Bevan D.R. (2009) Perturbation of membranes by the amyloid β-peptide - A molecular dynamics study. FEBS J 276:3060-3075.
-
(2009)
FEBS J
, vol.276
, pp. 3060-3075
-
-
Lemkul, J.A.1
Bevan, D.R.2
-
19
-
-
0347753786
-
Two Types of Alzheimer's β-Amyloid (1-40) Peptide Membrane Interactions: Aggregation Preventing Transmembrane Anchoring Versus Accelerated Surface Fibril Formation
-
DOI 10.1016/j.jmb.2003.11.046
-
Bokvist M., Lindström F., Watts A., Gröbner G. (2004) Two types of Alzheimer's β-amyloid (1-40) peptide membrane interactions: Aggregation preventing transmembrane anchoring versus accelerated surface fibril formation. J Mol Biol 335:1039-1049. (Pubitemid 38091609)
-
(2004)
Journal of Molecular Biology
, vol.335
, Issue.4
, pp. 1039-1049
-
-
Bokvist, M.1
Lindstrom, F.2
Watts, A.3
Grobner, G.4
-
20
-
-
44949154514
-
Lipid membrane templates the ordering and induces the fibrillogenesis of Alzheimer's disease amyloid-β peptide
-
DOI 10.1002/prot.21887
-
Chi E.Y., Ege C., Winans A., Majewski J., Wu G., Kjaer K., Lee K.Y.C. (2008) Lipid membrane templates the ordering and induces the fibrillogenesis of Alzheimer's disease amyloid-β peptide. Proteins 72:1-24. (Pubitemid 351809143)
-
(2008)
Proteins: Structure, Function and Genetics
, vol.72
, Issue.1
, pp. 1-24
-
-
Chi, E.Y.1
Ege, C.2
Winans, A.3
Majewski, J.4
Wu, G.5
Kjaer, K.6
Lee, K.Y.C.7
-
21
-
-
0037474240
-
Metal ions, pH, and cholesterol regulate the interactions of Alzheimer's disease amyloid-β peptide with membrane lipid
-
DOI 10.1074/jbc.M205455200
-
Curtain C.C., Ali F.E., Smith D.G., Bush A.I., Masters C.L., Barnham K.J. (2003) Metal ions, pH, and cholesterol regulate the interactions of Alzheimer's disease amyloid-βpeptide with membrane lipid. J Biol Chem 278: 2977-2982. (Pubitemid 36801204)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.5
, pp. 2977-2982
-
-
Curtain, C.C.1
Ali, F.E.2
Smith, D.G.3
Bush, A.I.4
Masters, C.L.5
Barnham, K.J.6
-
22
-
-
4444328762
-
Insertion of Alzheimer's Ab40 peptide into lipid monolayers
-
DOI 10.1529/biophysj.104.043265
-
Ege C., Lee K.Y.C. (2004) Insertion of Alzheimer's Ab40 peptide into lipid monolayers. Biophys J 87:1732-1740. (Pubitemid 39167029)
-
(2004)
Biophysical Journal
, vol.87
, Issue.3
, pp. 1732-1740
-
-
Ege, C.1
Lee, K.Y.C.2
-
23
-
-
0036889671
-
Membrane destabilization induced by β-amyloid peptide 29-42: Importance of the amino-terminus
-
DOI 10.1016/S0009-3084(02)00108-1, PII S0009308402001081
-
Mingeot-Leclercq M-P, Lins L., Bensliman M., Van Bambeke F., Van Der Smissen P., Peuvot J., Schanck A., Brasseur R. (2002) Membrane destabilization induced by β-amyloid peptide 29-42: Importance of the amino-terminus. Chem Phys Lipids 120:57-74. (Pubitemid 35333400)
-
(2002)
Chemistry and Physics of Lipids
, vol.120
, Issue.1-2
, pp. 57-74
-
-
Mingeot-Leclercq, M.-P.1
Lins, L.2
Bensliman, M.3
Van Bambeke, F.4
Van Der, S.P.5
Peuvot, J.6
Schanck, A.7
Brasseur, R.8
-
24
-
-
64549140676
-
Structural characterization of a soluble amyloid β-peptide oligomer
-
Yu L., Edalji R., Harlan J.E., Holzman T.F., Lopez A.P., Labkovsky B., Hillen H., Barghorn S., Ebert U., Richardson P.L., Miesbauer L., Solomon L., Bartley D., Walter K.,Johnson R.W., Hajduk P.J., Olejniczak E.T. (2009) Structural characterization of a soluble amyloid β-peptide oligomer. Biochemistry 48:1870-1877.
-
(2009)
Biochemistry
, vol.48
, pp. 1870-1877
-
-
Yu, L.1
Edalji, R.2
Harlan, J.E.3
Holzman, T.F.4
Lopez, A.P.5
Labkovsky, B.6
Hillen, H.7
Barghorn, S.8
Ebert, U.9
Richardson, P.L.10
Miesbauer, L.11
Solomon, L.12
Bartley, D.13
Walter, K.14
Johnson, R.W.15
Hajduk, P.J.16
Olejniczak, E.T.17
-
25
-
-
0037465708
-
Insights into the amyloid folding problem from solid-state NMR
-
Tycko R. (2003) Insights into the amyloid folding problem from solid-state NMR. Biochemistry 42:3151-3159.
-
(2003)
Biochemistry
, vol.42
, pp. 3151-3159
-
-
Tycko, R.1
-
26
-
-
28444442999
-
3D structure of Alzheimer's amyloid-β(1-42) fibrils
-
Lührs T., Ritter C., Adrian M., Riek-Loher D., Bohrmann B., Döbeli H., Schubert D., Riek R. (2005) 3D structure of Alzheimer's amyloid-β(1-42) fibrils. Proc Natl Acad Sci USA 102:17342-17347.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 17342-17347
-
-
Lührs, T.1
Ritter, C.2
Adrian, M.3
Riek-Loher, D.4
Bohrmann, B.5
Döbeli, H.6
Schubert, D.7
Riek, R.8
-
27
-
-
17244372981
-
Conformational transition of amyloid β-peptide
-
Xu Y., Shen J., Luo X., Zhu W., Chen K., Ma J., Jiang H. (2005) Conformational transition of amyloid β-peptide. Proc Natl Acad Sci USA 102:5403-5407.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 5403-5407
-
-
Xu, Y.1
Shen, J.2
Luo, X.3
Zhu, W.4
Chen, K.5
Ma, J.6
Jiang, H.7
-
28
-
-
0029781703
-
2+ binding
-
Müller E., Giehl A., Schwarzmann G., Sandhoff K., Blume A. (1996) Oriented 1,2-dimyristoyl-sn-glycerol-3-phosphorylcholine/ganglioside membranes: A Fourier transform infrared attenuated total reflection spectroscopic study. Band assignments; orientational, hydrational, and phase behavior; and effects of Ca2+ binding. Biophys J 71:1400-1421. (Pubitemid 26299779)
-
(1996)
Biophysical Journal
, vol.71
, Issue.3
, pp. 1400-1421
-
-
Muller, E.1
Giehl, A.2
Schwarzmann, G.3
Sandhoff, K.4
Blume, A.5
-
29
-
-
0028982292
-
Self-association of β-amyloid peptide (1-40) in solution and binding to lipid membranes
-
Terzi E., Hölzemann G., Seelig J. (1995) Self-association of β-amyloid peptide (1-40) in solution and binding to lipid membranes. J Mol Biol 252:633-642.
-
(1995)
J Mol Biol
, vol.252
, pp. 633-642
-
-
Terzi, E.1
Hölzemann, G.2
Seelig, J.3
-
30
-
-
0035870150
-
Characterization of high-affinity binding between gangliosides and amyloid β-protein
-
DOI 10.1006/abbi.2001.2304
-
Ariga T., Kobayashi K., Hasegawa A., Kiso M., Ishida H., Miyatake T. (2001) Characterization of high-affinity binding between gangliosides and amyloid β-protein. Arch Biochem Biophys 388:225-230. (Pubitemid 32911613)
-
(2001)
Archives of Biochemistry and Biophysics
, vol.388
, Issue.2
, pp. 225-230
-
-
Ariga, T.1
Kobayashi, K.2
Hasegawa, A.3
Kiso, M.4
Ishida, H.5
Miyatake, T.6
-
31
-
-
79954534373
-
Molecular basis for the glycosphingolipid-binding specificity of α-synuclein: Key role of tyrosine-39 in membrane insertion
-
Fantini J., Yahi N. (2011) Molecular basis for the glycosphingolipid- binding specificity of α-synuclein: Key role of tyrosine-39 in membrane insertion. J Mol Biol 408: 654-669.
-
(2011)
J Mol Biol
, vol.408
, pp. 654-669
-
-
Fantini, J.1
Yahi, N.2
-
32
-
-
0027944284
-
Theoretical models of the ion channel structure of amyloid β-protein
-
Durell S.R., Guy H.R., Arispe N., Rojas E., Pollard H.B. (1994) Theoretical models of the ion channel structure of amyloid β-protein. Biophys J 67:2137-2145. (Pubitemid 24369639)
-
(1994)
Biophysical Journal
, vol.67
, Issue.6
, pp. 2137-2145
-
-
Durell, S.R.1
Guy, H.R.2
Arispe, N.3
Rojas, E.4
Pollard, H.B.5
-
33
-
-
0030892291
-
Characterization of the interactions of Alzheimer β-amyloid peptides with phospholipid membranes
-
McLaurin J., Chakrabartty A. (1997) Characterization of the interactions of Alzheimer β-amyloid peptides with phospholipid membranes. Eur J Biochem 245:355-363. (Pubitemid 27171258)
-
(1997)
European Journal of Biochemistry
, vol.245
, Issue.2
, pp. 355-363
-
-
McLaurin, J.1
Chakrabartty, A.2
-
34
-
-
0026673537
-
Effects of sulfate ions on Alzheimer β/A4 peptide assemblies: Implications for amyloid fibril-proteoglycan interactions
-
Fraser P.E., Nguyen J.T., Chin D.T., Kirschner D.A. (1992) Effects of sulfate ions on Alzheimer β/A4 peptide assemblies: Implications for amyloid fibril-proteoglycan interactions. J Neurochem 59:1531-1540.
-
(1992)
J Neurochem
, vol.59
, pp. 1531-1540
-
-
Fraser, P.E.1
Nguyen, J.T.2
Chin, D.T.3
Kirschner, D.A.4
-
35
-
-
0027504032
-
pH-dependent binding of synthetic β-amyloid peptides to glycosaminoglycans
-
DOI 10.1111/j.1471-4159.1993.tb07453.x
-
Brunden K.R., Richter-Cook N.J., Chaturvedi K., Frederickson R.C.A. (1993) pH-dependent binding of synthetic β-amyloid peptides to glycosaminoglycans. J Neurochem 61:2147-2154. (Pubitemid 23354072)
-
(1993)
Journal of Neurochemistry
, vol.61
, Issue.6
, pp. 2147-2154
-
-
Brunden, K.R.1
Richter-Cook, N.J.2
Chaturvedi, N.3
Frederickson, R.C.A.4
-
36
-
-
69549086151
-
Effect of trehalose on amyloid b (29-40)-membrane interaction
-
Reddy A.S., Izmitli A., De Pablo J.J. (2009) Effect of trehalose on amyloid b (29-40)-membrane interaction. J Chem Phys 131:085101.
-
(2009)
J Chem Phys
, vol.131
, pp. 085101
-
-
Reddy, A.S.1
Izmitli, A.2
De Pablo, J.J.3
-
37
-
-
0035118736
-
Amyloid-b peptide assembly: A critical step in fibrillogenesis and membrane disruption
-
Yip C.M., McLaurin J. (2001) Amyloid-b peptide assembly: A critical step in fibrillogenesis and membrane disruption. Biophys J 80:1359-1371. (Pubitemid 32182160)
-
(2001)
Biophysical Journal
, vol.80
, Issue.3
, pp. 1359-1371
-
-
Yip, C.M.1
McLaurin, J.2
-
38
-
-
17744391390
-
Fusogenic Alzheimer's peptide fragment Aβ (29-42) in interaction with lipid bilayers: Secondary structure, dynamics, and specific interaction with phosphatidyl ethanolamine polar heads as revealed by solid-state NMR
-
DOI 10.1110/ps.041291405
-
Ravault S., Soubias O., Saurel O., Thomas A., Brasseur R., Milon A. (2005) Fusogenic Alzheimer's peptide fragment Aβ (29-42) in interaction with lipid bilayers: Secondary structure, dynamics, and specific interaction with phosphatidyl ethanolamine polar heads as revealed by solid-state NMR. Protein Sci 14:1181-1189. (Pubitemid 40577798)
-
(2005)
Protein Science
, vol.14
, Issue.5
, pp. 1181-1189
-
-
Ravault, S.1
Soubias, O.2
Saurel, O.3
Thomas, A.4
Brasseur, R.5
Milon, A.6
-
39
-
-
2942666417
-
Modeling amyloid β-peptide insertion into lipid bilayers
-
DOI 10.1529/biophysj.103.032342
-
Mobley D.L., Cox D.L., Singh R.R.P., Maddox M.W., Longo M.L. (2004) Modeling amyloid β-peptide insertion into lipid bilayers. Biophys J 86:3585-3597. (Pubitemid 38780238)
-
(2004)
Biophysical Journal
, vol.86
, Issue.6
, pp. 3585-3597
-
-
Mobley, D.L.1
Cox, D.L.2
Singh, R.R.P.3
Maddox, M.W.4
Longo, M.L.5
-
40
-
-
61549084018
-
Interaction between amyloid-β (1-42) peptide and phospholipid bilayers: A molecular dynamics study
-
Davis C.H., Berkowitz M.L. (2009) Interaction between amyloid-β (1-42) peptide and phospholipid bilayers: A molecular dynamics study. Biophys J 96:785-797.
-
(2009)
Biophys J
, vol.96
, pp. 785-797
-
-
Davis, C.H.1
Berkowitz, M.L.2
-
41
-
-
70350397192
-
Structure of the amyloid- β (1-42) monomer absorbed to model phospholipid bilayers: A molecular dynamics study
-
Davis C.H., Berkowitz M.L. (2009) Structure of the amyloid- β (1-42) monomer absorbed to model phospholipid bilayers: a molecular dynamics study. J Phys Chem B 113:14480-11486.
-
(2009)
J Phys Chem B
, vol.113
, pp. 14480-111486
-
-
Davis, C.H.1
Berkowitz, M.L.2
-
42
-
-
46749127364
-
Are current molecular dynamics force fields too helical?
-
Best R.B., Buchete N-V, Hummer G. (2008) Are current molecular dynamics force fields too helical? Biophys J 95:L07-L09.
-
(2008)
Biophys J
, vol.95
-
-
Best, R.B.1
Buchete, N.-V.2
Hummer, G.3
-
43
-
-
68949107624
-
Secondary structure propensities in peptide folding simulations: A systematic comparison of molecular mechanics interaction schemes
-
Matthes D., De Groot B.L. (2009) Secondary structure propensities in peptide folding simulations: A systematic comparison of molecular mechanics interaction schemes. Biophys J 97:599-608.
-
(2009)
Biophys J
, vol.97
, pp. 599-608
-
-
Matthes, D.1
De Groot, B.L.2
-
44
-
-
61949248657
-
Effect of dehydration on the aggregation kinetics of two amyloid peptides
-
Mukherjee S., Chowdhury P., Gai F. (2009) Effect of dehydration on the aggregation kinetics of two amyloid peptides. J Phys Chem B 113:531-535.
-
(2009)
J Phys Chem B
, vol.113
, pp. 531-535
-
-
Mukherjee, S.1
Chowdhury, P.2
Gai, F.3
-
45
-
-
0025840201
-
B A4 amyloid protein deposition in brain after head trauma
-
Roberts G.W., Gentleman S.M., Lynch A., Graham D.I. (1991) b A4 amyloid protein deposition in brain after head trauma. Lancet 338:1422-1423.
-
(1991)
Lancet
, vol.338
, pp. 1422-1423
-
-
Roberts, G.W.1
Gentleman, S.M.2
Lynch, A.3
Graham, D.I.4
-
46
-
-
34249734831
-
Depletion of GGA3 Stabilizes BACE and Enhances β-Secretase Activity
-
DOI 10.1016/j.neuron.2007.05.012, PII S0896627307003467
-
Tesco G., Koh Y.H., Kang E.L., Cameron A.N., Das S., Sena-Esteves M., Hiltunen M., Yang S-H, Zhong Z., Shen Y., Simpkins J.W., Tanzi R.E. (2007) Depletion of GGA3 stabilizes BACE and enhances β-secretase activity. Neuron 54:721-737. (Pubitemid 46843521)
-
(2007)
Neuron
, vol.54
, Issue.5
, pp. 721-737
-
-
Tesco, G.1
Koh, Y.H.2
Kang, E.L.3
Cameron, A.N.4
Das, S.5
Sena-Esteves, M.6
Hiltunen, M.7
Yang, S.-H.8
Zhong, Z.9
Shen, Y.10
Simpkins, J.W.11
Tanzi, R.E.12
-
47
-
-
0032951553
-
Alamethicin helices in a bilayer and in solution: Molecular dynamics simulations
-
Tieleman D.P., Sansom M.S.P., Berendsen H.J.C. (1999) Alamethicin helices in a bilayer and in solution: Molecular dynamics simulations. Biophys J 76:40-49. (Pubitemid 29202436)
-
(1999)
Biophysical Journal
, vol.76
, Issue.1 I
, pp. 40-49
-
-
Tieleman, D.P.1
Sansom, M.S.P.2
Berendsen, H.J.C.3
-
48
-
-
1542285301
-
+ Counterions and NaCl
-
Mukhopadhyay P., Monticelli L., Tieleman D.P. (2004) Molecular dynamics simulation of a palmitoyl-oleoyl phosphatidylserine bilayer with Na+ counterions and NaCl. Biophys J 86:1601-1609. (Pubitemid 38295593)
-
(2004)
Biophysical Journal
, vol.86
, Issue.3
, pp. 1601-1609
-
-
Mukhopadhyay, P.1
Monticelli, L.2
Tieleman, D.P.3
-
49
-
-
41649087624
-
Experimental and computational studies investigating trehalose protection of HepG2 cells from palmitate-induced toxicity
-
Leekumjorn S., Wu Y., Sum A.K., Chan C. (2008) Experimental and computational studies investigating trehalose protection of HepG2 cells from palmitate-induced toxicity. Biophys J 94:2869-2883.
-
(2008)
Biophys J
, vol.94
, pp. 2869-2883
-
-
Leekumjorn, S.1
Wu, Y.2
Sum, A.K.3
Chan, C.4
-
50
-
-
0032534843
-
Lipid properties and the orientation of aromatic residues in OmpF, influenza M2, and alamethicin systems: Molecular dynamics simulations
-
Tieleman D.P., Forrest L.R., Sansom M.S.P., Berendsen H.J.C. (1998) Lipid properties and the orientation of aromatic residues in OmpF, influenza M2, and alamethicin systems: Molecular dynamics simulations. Biochemistry 37:17554-17561.
-
(1998)
Biochemistry
, vol.37
, pp. 17554-17561
-
-
Tieleman, D.P.1
Forrest, L.R.2
Sansom, M.S.P.3
Berendsen, H.J.C.4
-
51
-
-
33847249878
-
Assessing the nature of lipid raft membranes
-
Niemelä P.S., Ollila S., Hyvönen M.T., Karttunen M., Vattulainen I. (2007) Assessing the nature of lipid raft membranes. PLoS Comp Biol 3:e34.
-
(2007)
PLoS Comp Biol
, vol.3
-
-
Niemelä, P.S.1
Ollila, S.2
Hyvönen, M.T.3
Karttunen, M.4
Vattulainen, I.5
-
53
-
-
4444282928
-
A biomolecular force field based on the free enthalpy of hydration and solvation: The GROMOS force-field parameter sets 53A5 and 53A6
-
Oostenbrink C., Villa A., Mark A.E., Van Gunsteren W.F. (2004) A biomolecular force field based on the free enthalpy of hydration and solvation: The GROMOS force-field parameter sets 53A5 and 53A6. J Comput Chem 25:1656-1676.
-
(2004)
J Comput Chem
, vol.25
, pp. 1656-1676
-
-
Oostenbrink, C.1
Villa, A.2
Mark, A.E.3
Van Gunsteren, W.F.4
-
54
-
-
0030999097
-
Molecular dynamics simulations of a fluid bilayer of dipalmitoylphosphatidylcholine at full hydration, constant pressure, and constant temperature
-
Berger O., Edholm O., Jähnig F. (1997) Molecular dynamics simulations of a fluid bilayer of dipalmitoylphosphatidylcholine at full hydration, constant pressure, and constant temperature. Biophys J 72: 2002-2013. (Pubitemid 27184429)
-
(1997)
Biophysical Journal
, vol.72
, Issue.5
, pp. 2002-2013
-
-
Berger, O.1
Edholm, O.2
Jahnig, F.3
-
55
-
-
0032483035
-
Solution structure of amyloid β-peptide(1-40) in a water-micelle environment. Is the membrane-spanning domain where we think it is?
-
DOI 10.1021/bi972979f, PII S0006296097029796
-
Coles M., Bicknell W., Watson A.A., Fairlie D.P., Craik D.J. (1998) Solution structure of amyloid β-peptide(1-40) in a water-micelle environment. Is the membrane-spanning domain where we think it is? Biochemistry 37: 11064-11077. (Pubitemid 28368933)
-
(1998)
Biochemistry
, vol.37
, Issue.31
, pp. 11064-11077
-
-
Coles, M.1
Bicknell, W.2
Watson, R.A.3
Fairlie, D.P.4
Craik, D.J.5
-
56
-
-
33947139278
-
Setting up and running molecular dynamics simulations of membrane proteins
-
DOI 10.1016/j.ymeth.2006.08.006, PII S1046202306001873
-
Kandt C., Ash W.L., Tieleman D.P. (2007) Setting up and running molecular dynamics simulations of membrane proteins. Methods 41:475-488. (Pubitemid 46400527)
-
(2007)
Methods
, vol.41
, Issue.4
, pp. 475-488
-
-
Kandt, C.1
Ash, W.L.2
Peter, T.D.3
-
57
-
-
0002775934
-
Interaction models for water in relation to protein hydration
-
Pullman B, Ed Dordrecht: Reidel
-
Berendsen H.J.C., Postma J.P.M., Van Gunsteren W.F., Hermans J, Interaction models for water in relation to protein hydration In: Pullman B, Ed (1981) Intermolecular forces. Dordrecht: Reidel, p 331.
-
(1981)
Intermolecular Forces
, pp. 331
-
-
Berendsen, H.J.C.1
Postma, J.P.M.2
Van Gunsteren, W.F.3
Hermans, J.4
-
58
-
-
51549106517
-
Structural studies of the transmembrane C-terminal domain of the amyloid precursor protein (APP): Does APP function as a cholesterol sensor?
-
Beel A.J., Mobley C.K., Kim H.J., Tian F., Hadziselimovic A., Jap B., Prestegard J.H., Sanders C.R. (2008) Structural studies of the transmembrane C-terminal domain of the amyloid precursor protein (APP): Does APP function as a cholesterol sensor? Biochemistry 47: 9428-9446.
-
(2008)
Biochemistry
, vol.47
, pp. 9428-9446
-
-
Beel, A.J.1
Mobley, C.K.2
Kim, H.J.3
Tian, F.4
Hadziselimovic, A.5
Jap, B.6
Prestegard, J.H.7
Sanders, C.R.8
-
59
-
-
46249092554
-
GROMACS 4: Algorithms for highly efficient, load-balanced, and scalable molecular simulation
-
Hess B., Kutzner C., Van der Spoel D., Lindahl E. (2008) GROMACS 4: Algorithms for highly efficient, load-balanced, and scalable molecular simulation. J Chem Theory Comput 4:435-447.
-
(2008)
J Chem Theory Comput
, vol.4
, pp. 435-447
-
-
Hess, B.1
Kutzner, C.2
Van Der Spoel, D.3
Lindahl, E.4
-
60
-
-
33846823909
-
Particle mesh Ewald: An N·log(N) method for Ewald sums in large systems
-
Darden T., York D., Pedersen L. (1993) Particle mesh Ewald: An N·log(N) method for Ewald sums in large systems. J Chem Phys 98:10089-10092.
-
(1993)
J Chem Phys
, vol.98
, pp. 10089-10092
-
-
Darden, T.1
York, D.2
Pedersen, L.3
-
61
-
-
33645961739
-
A smooth particle mesh Ewald method
-
Essmann U., Perera L., Berkowitz M.L., Darden T., Lee H., Pedersen L.G. (1995) A smooth particle mesh Ewald method. J Chem Phys 103:8577-8593.
-
(1995)
J Chem Phys
, vol.103
, pp. 8577-8593
-
-
Essmann, U.1
Perera, L.2
Berkowitz, M.L.3
Darden, T.4
Lee, H.5
Pedersen, L.G.6
-
62
-
-
38749123962
-
P-LINCS: A parallel linear constraint solver for molecular simulation
-
Hess B. (2008) P-LINCS: A parallel linear constraint solver for molecular simulation. J Chem Theory Comput 4:116-122.
-
(2008)
J Chem Theory Comput
, vol.4
, pp. 116-122
-
-
Hess, B.1
-
63
-
-
33750587438
-
Molecular dynamics with coupling to an external bath
-
Berendsen H.J.C., Postma J.P.M., Van Gunsteren W.F., DiNola A., Haak J.R. (1984) Molecular dynamics with coupling to an external bath. J Chem Phys 81:3684-3690.
-
(1984)
J Chem Phys
, vol.81
, pp. 3684-3690
-
-
Berendsen, H.J.C.1
Postma, J.P.M.2
Van Gunsteren, W.F.3
DiNola, A.4
Haak, J.R.5
-
64
-
-
34547809547
-
A unified formulation of the constant temperature molecular dynamics methods
-
Nosé S. (1984) A unified formulation of the constant temperature molecular dynamics methods. J Chem Phys 81:511-519.
-
(1984)
J Chem Phys
, vol.81
, pp. 511-519
-
-
Nosé, S.1
-
65
-
-
0001538909
-
Canonical dynamics: Equilibrium phase-space distributions
-
Hoover W.G. (1985) Canonical dynamics: Equilibrium phase-space distributions. Phys Rev A: At Mol Opt Phys 31:1695-1697.
-
(1985)
Phys Rev A: At Mol Opt Phys
, vol.31
, pp. 1695-1697
-
-
Hoover, W.G.1
-
66
-
-
0019707626
-
POLYMORPHIC TRANSITIONS IN SINGLE CRYSTALS: A NEW MOLECULAR DYNAMICS METHOD.
-
DOI 10.1063/1.328693
-
Parrinello M., Rahman A. (1981) Polymorphic transitions in single crystals: A new molecular dynamics method. J Appl Phys 52:7182-7190. (Pubitemid 12456820)
-
(1981)
Journal of Applied Physics
, vol.52
, Issue.12
, pp. 7182-7190
-
-
Parrinello, M.1
Rahman, A.2
-
67
-
-
84926811618
-
Constant pressure molecular dynamics for molecular systems
-
Nosé S., Klein M.L. (1983) Constant pressure molecular dynamics for molecular systems. Mol Phys 50: 1055-1076.
-
(1983)
Mol Phys
, vol.50
, pp. 1055-1076
-
-
Nosé, S.1
Klein, M.L.2
-
68
-
-
0020997912
-
Dictionary of protein secondary structure: Pattern recognition of hydrogenbonded and geometrical features
-
Kabsch W., Sander C. (1983) Dictionary of protein secondary structure: Pattern recognition of hydrogenbonded and geometrical features. Biopolymers 22: 2577-2637.
-
(1983)
Biopolymers
, vol.22
, pp. 2577-2637
-
-
Kabsch, W.1
Sander, C.2
|