Strategies for discovery and validation of methylated and hydroxymethylated DNA biomarkers

Cancer Medicine

Volumn 1, Issue 2, 2012, Pages 237-260

  Olkhov Mitsel, Ekaterina ^a,b   Bapat, Bharati ^a,b,c  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

Affinity based methylation analysis; Bisulfite modification; Hydroxymethylation; Methylation sensitive restriction enzymes; Microarrays; Next generation sequencing

Indexed keywords

5 CARBOXYLCYTOSINE; 5 FORMYLCYTOSINE; 5 HYDROXYMETHYLCYTOSINE; 5 METHYLCYTOSINE; BIOLOGICAL MARKER; DNA; UNCLASSIFIED DRUG;

AFFINITY BASED ANALYSIS; BISULFITE MODIFICATION; CPG ISLAND; DIAGNOSIS; DISEASE MARKER; DNA HYDROXYMETHYLATION; DNA METHYLATION; DNA SEQUENCE; EPIGENETICS; GENE LOCUS; GENETIC ANALYSIS; GENETIC ASSOCIATION; HUMAN; MICROARRAY ANALYSIS; NONHUMAN; PATIENT MONITORING; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; RESTRICTION ENZYME DIGESTION; REVIEW; TREATMENT RESPONSE; VALIDATION STUDY;

EID: 84887129061     PISSN: None     EISSN: 20457634     Source Type: Journal    
DOI: 10.1002/cam4.22     Document Type: Review

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