The implications of heterogeneous DNA methylation for the accurate quantification of methylation

Epigenomics

Volumn 2, Issue 4, 2010, Pages 561-573

  Mikeska, Thomas ^a,b   Candiloro, Ida L M ^a,b   Dobrovic, Alexander ^a,b  

^a PETER MACCALLUM CANCER CENTRE   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

biomarker; cancer; CDKN2B; digital PCR; high resolution melting; MGMT; minimal residual disease; molecular diagnostics

Indexed keywords

TUMOR MARKER;

ALLELE; COMBINED BISULFITE RESTRICTION ANALYSIS; CPG ISLAND; DNA METHYLATION; GENE AMPLIFICATION; GENE LOCUS; GENE SEQUENCE; GENE SILENCING; GENETIC PROCEDURES; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; METHYLATION SENSITIVE SINGLE NUCLEOTIDE PRIMER EXTENSION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; REVIEW; SEQUENCE ANALYSIS;

ALLELES; CPG ISLANDS; CYCLIN-DEPENDENT KINASE INHIBITOR P15; DNA METHYLATION; GENETIC HETEROGENEITY; HUMANS; MASS SPECTROMETRY; NEOPLASMS; POLYMERASE CHAIN REACTION; RESTRICTION MAPPING; SEQUENCE ANALYSIS, DNA; SULFITES; TRANSITION TEMPERATURE; TUMOR MARKERS, BIOLOGICAL;

EID: 77955450160     PISSN: 17501911     EISSN: 1750192X     Source Type: Journal    
DOI: 10.2217/epi.10.32     Document Type: Review

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