Pipeline for large-scale microdroplet bisulfite PCR-based sequencing allows the tracking of hepitype evolution in tumors

PLoS ONE

Volumn 6, Issue 7, 2011, Pages

  Herrmann, Alexander ^a   Haake, Andrea ^a   Ammerpohl, Ole ^a   Martin Guerrero, Idoia ^a   Szafranski, Karol ^b   Stemshorn, Kathryn ^c   Nothnagel, Michael ^a   Kotsopoulos, Steve K ^d   Richter, Julia ^a   Warner, Jason ^d   Olson, Jeff ^d   Link, Darren R ^a   Schreiber, Stefan ^a   Krawczak, Michael ^a   Platzer, Matthias ^b   Nürnberg, Peter ^c   Siebert, Reiner ^a   Hampe, Jochen ^a  

^a UNIVERSITY OF KIEL   (Germany)

^b FRITZ LIPMANN INSTITUTE   (Germany)

^c UNIVERSITY OF COLOGNE   (Germany)

^d RainDance Technologies   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BISULFITE; DNA; FGF6 PROTEIN, HUMAN; FIBROBLAST GROWTH FACTOR 6; HEPARITIN SULFOTRANSFERASE; SMALL NUCLEAR RIBONUCLEOPROTEIN; SNRPN PROTEIN, HUMAN; SULFITE; SULFOTRANSFERASE;

ARTICLE; CANCER GENETICS; COLORECTAL CANCER; CONTROLLED STUDY; DNA DETERMINATION; DNA METHYLATION; DNA SEQUENCE; FIBROBLAST GROWTH FACTOR 6 GENE; GENE TARGETING; HAPLOTYPE; HEPARAN SULFATE 3 O SULFOTRANSFERASE 2 GENE; LYMPHOMA; MOLECULAR EVOLUTION; PHYLOGENETIC TREE; POLYMERASE CHAIN REACTION; PROMOTER REGION; PYROSEQUENCING; REPRODUCIBILITY; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; SMALL NUCLEAR RIBONUCLEOPROTEIN POLYPEPTIDE N GENE; TUMOR GENE; AGED; CHEMISTRY; CLASSIFICATION; COLON TUMOR; FEMALE; FOLLICULAR LYMPHOMA; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENETICS; HUMAN; HUMAN GENOME; MALE; METHODOLOGY; MIDDLE AGED; NEOPLASM; PHYLOGENY;

AGED; COLONIC NEOPLASMS; DNA METHYLATION; DNA, NEOPLASM; FEMALE; FIBROBLAST GROWTH FACTOR 6; GENETIC PREDISPOSITION TO DISEASE; GENOME, HUMAN; GENOME-WIDE ASSOCIATION STUDY; HAPLOTYPES; HUMANS; LYMPHOMA, FOLLICULAR; MALE; MIDDLE AGED; NEOPLASMS; PHYLOGENY; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ANALYSIS, DNA; SNRNP CORE PROTEINS; SULFITES; SULFOTRANSFERASES;

EID: 79959923864     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0021332     Document Type: Article

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