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Volumn 58, Issue 6, 1998, Pages 1245-1252

The role of DNA methylation in expression of the p19/p16 locus in human bladder cancer cell lines

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; PROTEIN P16; PROTEIN P19; UNCLASSIFIED DRUG;

EID: 0032521402     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (212)

References (57)
  • 1
    • 0026708177 scopus 로고
    • Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
    • Li, E., Bestor, T., and Jaenisch, R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell, 69: 915-926, 1992.
    • (1992) Cell , vol.69 , pp. 915-926
    • Li, E.1    Bestor, T.2    Jaenisch, R.3
  • 2
    • 0027287437 scopus 로고
    • Genomic imprinting and gene activation in cancer
    • Feinberg, A. P. Genomic imprinting and gene activation in cancer. Nat Genet., 4: 110-113, 1993.
    • (1993) Nat Genet. , vol.4 , pp. 110-113
    • Feinberg, A.P.1
  • 3
    • 0028776070 scopus 로고
    • Genomic imprinting, DNA methylation, and cancer
    • Rainier, S., and Feinberg, A. P. Genomic imprinting, DNA methylation, and cancer. J. Natl. Cancer Inst., 86: 753-759, 1994.
    • (1994) J. Natl. Cancer Inst. , vol.86 , pp. 753-759
    • Rainier, S.1    Feinberg, A.P.2
  • 4
    • 0027172684 scopus 로고
    • Parental origin-specific epigenetic modification of the mouse H19 gene
    • Ferguson-Smith, A. C., Sasaki, H., Cattanach, B. M., and Surani, M. A. Parental origin-specific epigenetic modification of the mouse H19 gene. Nature (Lond.), 362: 751-755, 1993.
    • (1993) Nature (Lond.) , vol.362 , pp. 751-755
    • Ferguson-Smith, A.C.1    Sasaki, H.2    Cattanach, B.M.3    Surani, M.A.4
  • 5
    • 0027378582 scopus 로고
    • Role for DNA methylation in genomic imprinting
    • Li, E., Beard, C., and Jaenisch, R. Role for DNA methylation in genomic imprinting. Nature (Lond.), 366: 362-365, 1993.
    • (1993) Nature (Lond.) , vol.366 , pp. 362-365
    • Li, E.1    Beard, C.2    Jaenisch, R.3
  • 6
    • 0025119812 scopus 로고
    • Polymerase chain reaction-aided genomic sequencing of an X chromosome-linked CpG island: Methylation patterns suggest clonal inheritance, CpG site autonomy, and an explanation of activity state stability
    • Pfeifer, G. P., Steigerwald, S. D., Hansen, R. S., Gartler, S. M., and Riggs, A. D. Polymerase chain reaction-aided genomic sequencing of an X chromosome-linked CpG island: methylation patterns suggest clonal inheritance, CpG site autonomy, and an explanation of activity state stability. Proc. Natl. Acad. Sci. USA, 87: 8252-8256, 1990.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 8252-8256
    • Pfeifer, G.P.1    Steigerwald, S.D.2    Hansen, R.S.3    Gartler, S.M.4    Riggs, A.D.5
  • 7
    • 0023815650 scopus 로고
    • Demethylation of specific sites in the 5′ region of the inactive X-linked human phosphoglycerate kinase gene correlates with the appearance of nuclease sensitivity and gene expression
    • Hansen, R. S., Ellis, N. A., and Gartler, S. M. Demethylation of specific sites in the 5′ region of the inactive X-linked human phosphoglycerate kinase gene correlates with the appearance of nuclease sensitivity and gene expression. Mol. Cell. Biol., 8: 4692-4699, 1988.
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 4692-4699
    • Hansen, R.S.1    Ellis, N.A.2    Gartler, S.M.3
  • 8
    • 0027537296 scopus 로고
    • CpG methylation inactivates the promoter activity of the human retinoblastoma tumor-suppressor gene
    • Ohtani Fujita, N., Fujita, T., Aoike, A., Osifchin, N. E., Robbins, P. D., and Sakai, T. CpG methylation inactivates the promoter activity of the human retinoblastoma tumor-suppressor gene. Oncogene, 8: 1063-1067, 1993.
    • (1993) Oncogene , vol.8 , pp. 1063-1067
    • Ohtani Fujita, N.1    Fujita, T.2    Aoike, A.3    Osifchin, N.E.4    Robbins, P.D.5    Sakai, T.6
  • 9
    • 0027496294 scopus 로고
    • Imprinting of human H19: Allele-specific CpG methylation, loss of the active allele in Wilms tumor, and potential for somatic allele switching
    • Zhang, Y., Shields, T., Crenshaw, T., Hao, Y., Moulton, T., and Tycko, B. Imprinting of human H19: allele-specific CpG methylation, loss of the active allele in Wilms tumor, and potential for somatic allele switching. Am. J. Hum. Genet 53: 113-124, 1993.
    • (1993) Am. J. Hum. Genet , vol.53 , pp. 113-124
    • Zhang, Y.1    Shields, T.2    Crenshaw, T.3    Hao, Y.4    Moulton, T.5    Tycko, B.6
  • 11
    • 0029011539 scopus 로고
    • 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
    • Merlo, A., Herman, J. G., Mao, L., Lee, D. J., Gabrielson, E., Burger, P. C., Baylin, S. B., and Sidransky, D. 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Nat. Med., 1: 686-692, 1995.
    • (1995) Nat. Med. , vol.1 , pp. 686-692
    • Merlo, A.1    Herman, J.G.2    Mao, L.3    Lee, D.J.4    Gabrielson, E.5    Burger, P.C.6    Baylin, S.B.7    Sidransky, D.8
  • 12
    • 0029898837 scopus 로고    scopus 로고
    • DNA methylation errors and cancer
    • Jones, P. A. DNA methylation errors and cancer. Cancer Res., 56: 2463-2467, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 2463-2467
    • Jones, P.A.1
  • 13
    • 0030902720 scopus 로고    scopus 로고
    • Mutagenic and epigenetic effects of DNA methylation
    • Gonzalgo, M. L., and Jones, P. A. Mutagenic and epigenetic effects of DNA methylation. Mutat. Res., 386: 107-118, 1997.
    • (1997) Mutat. Res. , vol.386 , pp. 107-118
    • Gonzalgo, M.L.1    Jones, P.A.2
  • 14
    • 0026076727 scopus 로고
    • Abnormal patterns of DNA methylation in human neoplasia: Potential consequences for tumor progression
    • Baylin, S. B., Makos, M., Wu, J. J., Yen, R. W., de Bustros, A., Vertino, P., and Nelkin, B. D. Abnormal patterns of DNA methylation in human neoplasia: potential consequences for tumor progression. Cancer Cells, 3: 383-390, 1991.
    • (1991) Cancer Cells , vol.3 , pp. 383-390
    • Baylin, S.B.1    Makos, M.2    Wu, J.J.3    Yen, R.W.4    De Bustros, A.5    Vertino, P.6    Nelkin, B.D.7
  • 15
    • 0026742792 scopus 로고
    • CpG islands as gene markers in the human genome
    • Larsen, F., Gundersen, G., Lopez, R., and Prydz, H. CpG islands as gene markers in the human genome. Genomics, 13: 1095-1107, 1992.
    • (1992) Genomics , vol.13 , pp. 1095-1107
    • Larsen, F.1    Gundersen, G.2    Lopez, R.3    Prydz, H.4
  • 16
    • 0022540321 scopus 로고
    • CpG-rich islands and the function of DNA methylation
    • Bird, A. P. CpG-rich islands and the function of DNA methylation. Nature (Lond.), 321: 209-213, 1986.
    • (1986) Nature (Lond.) , vol.321 , pp. 209-213
    • Bird, A.P.1
  • 17
    • 0030115772 scopus 로고    scopus 로고
    • Creation of genomic methylation patterns
    • Bestor, T. H., and Tycko, B. Creation of genomic methylation patterns. Nat. Genet., 12: 363-367, 1996.
    • (1996) Nat. Genet. , vol.12 , pp. 363-367
    • Bestor, T.H.1    Tycko, B.2
  • 18
    • 0030840954 scopus 로고    scopus 로고
    • Cytosine methylation and the ecology of intragenomic parasites
    • Yoder, J. A., Walsh, C. P., and Bestor, T. H. Cytosine methylation and the ecology of intragenomic parasites. Trends Genet., 13: 335-340, 1997.
    • (1997) Trends Genet. , vol.13 , pp. 335-340
    • Yoder, J.A.1    Walsh, C.P.2    Bestor, T.H.3
  • 19
    • 0026653420 scopus 로고
    • The essentials of DNA methylation
    • Bird, A. P. The essentials of DNA methylation. Cell, 70: 5-8, 1992.
    • (1992) Cell , vol.70 , pp. 5-8
    • Bird, A.P.1
  • 20
    • 0023216891 scopus 로고
    • CpG islands in vertebrate genomes
    • Gardiner-Garden, M., and Frommer, M. CpG islands in vertebrate genomes. J. Mol. Biol., 196: 261-282, 1987.
    • (1987) J. Mol. Biol. , vol.196 , pp. 261-282
    • Gardiner-Garden, M.1    Frommer, M.2
  • 21
    • 0030479536 scopus 로고    scopus 로고
    • The origin of interspersed repeats in the human genome
    • Smit, A. F. The origin of interspersed repeats in the human genome. Curr. Opin. Genet. Dev., 6: 743-748, 1996.
    • (1996) Curr. Opin. Genet. Dev. , vol.6 , pp. 743-748
    • Smit, A.F.1
  • 22
    • 0029685023 scopus 로고    scopus 로고
    • Alu: Structure, origin, evolution, significance and function of one-tenth of human DNA
    • Schmid, C. W. Alu: structure, origin, evolution, significance and function of one-tenth of human DNA. Prog. Nucleic Acid Res. Mol. Biol., 53: 283-319, 1996.
    • (1996) Prog. Nucleic Acid Res. Mol. Biol. , vol.53 , pp. 283-319
    • Schmid, C.W.1
  • 23
    • 0028356544 scopus 로고
    • Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms' tumour
    • Steenman, M. J., Rainier, S., Dobry, C. J., Grundy, P., Horon, I. L., and Feinberg, A. P. Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms' tumour. Nat. Genet., 7: 433-439, 1994.
    • (1994) Nat. Genet. , vol.7 , pp. 433-439
    • Steenman, M.J.1    Rainier, S.2    Dobry, C.J.3    Grundy, P.4    Horon, I.L.5    Feinberg, A.P.6
  • 24
    • 0026781474 scopus 로고
    • Parental imprinting: Potentially active chromatin of the repressed maternal allele of the mouse insulin-like growth factor II (Igf2) gene
    • Sasaki, M., Jones, P. A., Chaillet, J. R., Ferguson-Smith, A. C., Barton, S. C., Reik, W., and Surani, M. A. Parental imprinting: potentially active chromatin of the repressed maternal allele of the mouse insulin-like growth factor II (Igf2) gene. Genes Dev., 6: 1843-1856, 1992.
    • (1992) Genes Dev. , vol.6 , pp. 1843-1856
    • Sasaki, M.1    Jones, P.A.2    Chaillet, J.R.3    Ferguson-Smith, A.C.4    Barton, S.C.5    Reik, W.6    Surani, M.A.7
  • 25
    • 0027769876 scopus 로고
    • A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
    • Serrano, M., Hannon, G. J., and Beach, D. A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature (Lond.), 366: 704-707, 1993.
    • (1993) Nature (Lond.) , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3
  • 28
    • 0028275733 scopus 로고
    • Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers
    • Nobori, T., Miura, K., Wu, D. J., Lois, A., Takabayashi, K., and Carson, D. A. Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature (Lond.), 368: 753-756, 1994.
    • (1994) Nature (Lond.) , vol.368 , pp. 753-756
    • Nobori, T.1    Miura, K.2    Wu, D.J.3    Lois, A.4    Takabayashi, K.5    Carson, D.A.6
  • 29
    • 0030025518 scopus 로고    scopus 로고
    • Compilation of somatic mutations of the CDKN2 gene in human cancers: Non-random distribution of base substitutions
    • Pollock, P. M., Pearson, J. V., and Hayward, N. K. Compilation of somatic mutations of the CDKN2 gene in human cancers: non-random distribution of base substitutions. Genes Chromosomes Cancer, 15: 77-88, 1996.
    • (1996) Genes Chromosomes Cancer , vol.15 , pp. 77-88
    • Pollock, P.M.1    Pearson, J.V.2    Hayward, N.K.3
  • 30
    • 0028071555 scopus 로고
    • Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular palhogenesis
    • Greenblatt, M. S., Bennett, W. P., Hollstein, M., and Harris, C. C. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular palhogenesis. Cancer Res., 54: 4855-4878, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 4855-4878
    • Greenblatt, M.S.1    Bennett, W.P.2    Hollstein, M.3    Harris, C.C.4
  • 31
    • 0028845142 scopus 로고
    • Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers
    • Herman, J. G., Merlo, A., Mao, L., Lapidus, R. G., Issa, J. P., Davidson, N. E., Sidransky, D., and Baylin, S. B. Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Res., 55: 4525-4530, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 4525-4530
    • Herman, J.G.1    Merlo, A.2    Mao, L.3    Lapidus, R.G.4    Issa, J.P.5    Davidson, N.E.6    Sidransky, D.7    Baylin, S.B.8
  • 33
    • 0028875205 scopus 로고
    • Methylation of the 5′ CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing
    • Gonzalez-Zulueta, M., Bender, C. M., Yang, A. S., Nguyen, T., Beart, R. W., Van Tornout, J. M., and Jones, P. A. Methylation of the 5′ CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing. Cancer Res., 55: 4531-4535, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 4531-4535
    • Gonzalez-Zulueta, M.1    Bender, C.M.2    Yang, A.S.3    Nguyen, T.4    Beart, R.W.5    Van Tornout, J.M.6    Jones, P.A.7
  • 35
    • 0029967152 scopus 로고    scopus 로고
    • Silencing of p16/CDKN2 expression in human gliomas by methylation and chromatin condensation
    • Costello, J. F., Berger, M. S., Huang, H. S., and Cavenee, W. K. Silencing of p16/CDKN2 expression in human gliomas by methylation and chromatin condensation. Cancer Res., 56: 2405-2410, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 2405-2410
    • Costello, J.F.1    Berger, M.S.2    Huang, H.S.3    Cavenee, W.K.4
  • 36
    • 9444268107 scopus 로고    scopus 로고
    • Inactivation of the CDKN2 gene by homozygous deletion and de novo methylation is associated with advanced stage esophageal squamous cell carcinoma
    • Maesawa, C., Tamura, G., Nishizuka, S., Ogasawara, S., Ishida, K., Terashima, M., Sakata, K., Sato, N., Saito, K., and Satodate, R. Inactivation of the CDKN2 gene by homozygous deletion and de novo methylation is associated with advanced stage esophageal squamous cell carcinoma. Cancer Res., 56: 3875-3878, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 3875-3878
    • Maesawa, C.1    Tamura, G.2    Nishizuka, S.3    Ogasawara, S.4    Ishida, K.5    Terashima, M.6    Sakata, K.7    Sato, N.8    Saito, K.9    Satodate, R.10
  • 39
    • 0029587551 scopus 로고
    • Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
    • Quelle, D. E., Zindy, F., Ashmun, R. A., and Sherr, C. J. Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest. Cell, 83: 993-1000, 1995.
    • (1995) Cell , vol.83 , pp. 993-1000
    • Quelle, D.E.1    Zindy, F.2    Ashmun, R.A.3    Sherr, C.J.4
  • 42
    • 0022032204 scopus 로고
    • Altering gene expression with 5-azacytidine
    • Jones, P. A. Altering gene expression with 5-azacytidine. Cell, 40: 485-486, 1985.
    • (1985) Cell , vol.40 , pp. 485-486
    • Jones, P.A.1
  • 43
    • 0031964055 scopus 로고    scopus 로고
    • Inhibition of DNA methylation by 5-aza-2′-deoxycytidine suppresses the growth of human tumor cell lines
    • Bender, C. M., Pao, M. M., and Jones, P. A. Inhibition of DNA methylation by 5-aza-2′-deoxycytidine suppresses the growth of human tumor cell lines. Cancer Res., 58: 95-101, 1998.
    • (1998) Cancer Res. , vol.58 , pp. 95-101
    • Bender, C.M.1    Pao, M.M.2    Jones, P.A.3
  • 44
    • 0029670840 scopus 로고    scopus 로고
    • Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence
    • Hara, E., Smith, R., Parry, D., Tahara, H., Stone, S., and Peters, G. Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence. Mol. Cell. Biol., 16: 859-867, 1996.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 859-867
    • Hara, E.1    Smith, R.2    Parry, D.3    Tahara, H.4    Stone, S.5    Peters, G.6
  • 45
    • 0001136210 scopus 로고
    • Gene activation by 5-azacytidine
    • A. Razin, H. Cedar, and A. D. Riggs (eds.), New York: Springer-Verlag
    • Jones, P. A. Gene activation by 5-azacytidine. In: A. Razin, H. Cedar, and A. D. Riggs (eds.), DNA Methylation: Biochemistry and Biological Significance, pp. 165-187. New York: Springer-Verlag, 1984.
    • (1984) DNA Methylation: Biochemistry and Biological Significance , pp. 165-187
    • Jones, P.A.1
  • 47
    • 0030738231 scopus 로고    scopus 로고
    • Rapid quantitation of methylation differences at specific sites using melhylation-sensitive single nucleotide primer extension (Ms-SNuPE)
    • Gonzalgo, M. L., and Jones, P. A. Rapid quantitation of methylation differences at specific sites using melhylation-sensitive single nucleotide primer extension (Ms-SNuPE). Nucleic Acids Res., 25: 2529-2531, 1997.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 2529-2531
    • Gonzalgo, M.L.1    Jones, P.A.2
  • 49
    • 0028840682 scopus 로고
    • Transcriptional activation of the Epstein-Barr virus latency C promoter after 5-aza-cytidine treatment: Evidence that demethylation at a single CpG site is crucial
    • Robertson, K. D., Hayward, S. D., Ling, P. D., Samid, D., and Ambinder, R. F. Transcriptional activation of the Epstein-Barr virus latency C promoter after 5-aza-cytidine treatment: evidence that demethylation at a single CpG site is crucial. Mol. Cell. Biol., 15: 6150-6159, 1995.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6150-6159
    • Robertson, K.D.1    Hayward, S.D.2    Ling, P.D.3    Samid, D.4    Ambinder, R.F.5
  • 50
    • 0026629881 scopus 로고
    • Vector methylation inhibits transcription from the SV40 early promoter
    • Bryans, M., Kass, S., Seivwright, C., and Adams, R. L. Vector methylation inhibits transcription from the SV40 early promoter. FEBS Lett., 309: 97-102, 1992.
    • (1992) FEBS Lett. , vol.309 , pp. 97-102
    • Bryans, M.1    Kass, S.2    Seivwright, C.3    Adams, R.L.4
  • 51
    • 0021050532 scopus 로고
    • Complete DNA methylation does not prevent polyoma and simian virus 40 virus early gene expression
    • Graessmann, M., Graessmann, A., Wagner, H., Werner, E., and Simon, D. Complete DNA methylation does not prevent polyoma and simian virus 40 virus early gene expression. Proc. Natl. Acad. Sci. USA, 80: 6470-6474, 1983.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 6470-6474
    • Graessmann, M.1    Graessmann, A.2    Wagner, H.3    Werner, E.4    Simon, D.5
  • 52
    • 0028333951 scopus 로고
    • Ubiquitous and tenacious methylation of the CpG site in codon 248 of the p53 gene may explain its frequent appearance as a mutational hotspot in human cancer
    • Magewu, A. N., and Jones, P. A. Ubiquitous and tenacious methylation of the CpG site in codon 248 of the p53 gene may explain its frequent appearance as a mutational hotspot in human cancer. Mol. Cell. Biol., 14: 4225-4232, 1994.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 4225-4232
    • Magewu, A.N.1    Jones, P.A.2
  • 53
    • 0029927415 scopus 로고    scopus 로고
    • The rate of CpG mutation in Alu repetitive elements within the p53 tumor suppressor gene in the primate germline
    • Yang, A. S., Gonzalgo, M. L., Zingg, J. M., Millar, R. P., Buckley, J. D., and Jones, P. A. The rate of CpG mutation in Alu repetitive elements within the p53 tumor suppressor gene in the primate germline. J. Mol. Biol., 258: 240-250, 1996.
    • (1996) J. Mol. Biol. , vol.258 , pp. 240-250
    • Yang, A.S.1    Gonzalgo, M.L.2    Zingg, J.M.3    Millar, R.P.4    Buckley, J.D.5    Jones, P.A.6
  • 54
    • 0028014280 scopus 로고
    • Enhancement of reporter gene de novo methylation by DNA fragments from the α-fetoprotein control region
    • Hasse, A., and Schulz, W. A. Enhancement of reporter gene de novo methylation by DNA fragments from the α-fetoprotein control region. J. Biol. Chem., 269: 1821-1826, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 1821-1826
    • Hasse, A.1    Schulz, W.A.2
  • 55
    • 0027253045 scopus 로고
    • A methylated CpG island 3′ in the apolipoprotein-E gene does not repress its transcription
    • Larsen, F., Solheim, J., and Prydz, H. A methylated CpG island 3′ in the apolipoprotein-E gene does not repress its transcription. Hum. Mol. Genet., 2: 775-780, 1993.
    • (1993) Hum. Mol. Genet. , vol.2 , pp. 775-780
    • Larsen, F.1    Solheim, J.2    Prydz, H.3
  • 56
    • 0027400888 scopus 로고
    • Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal
    • Stoger, R., Kubicka, P., Liu, C. G., Kafri, T., Razin, A., Cedar, H., and Barlow, D. P. Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal. Cell, 73: 61-71, 1993.
    • (1993) Cell , vol.73 , pp. 61-71
    • Stoger, R.1    Kubicka, P.2    Liu, C.G.3    Kafri, T.4    Razin, A.5    Cedar, H.6    Barlow, D.P.7
  • 57
    • 0021924990 scopus 로고
    • Effect of regional DNA methylation on gene expression
    • Keshet, I., Yisraeli, J., and Cedar, H. Effect of regional DNA methylation on gene expression. Proc. Natl. Acad. Sci. USA, 82: 2560-2564, 1985.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 2560-2564
    • Keshet, I.1    Yisraeli, J.2    Cedar, H.3


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