메뉴 건너뛰기




Volumn 32, Issue 5, 2011, Pages 741-747

Promoter methylation of Wnt antagonists DKK1 and SFRP1 is associated with opposing tumor subtypes in two large populations of colorectal cancer patients

Author keywords

[No Author keywords available]

Indexed keywords

DICKKOPF 1 PROTEIN; SECRETED FRIZZLED RELATED PROTEIN 1;

EID: 79955773267     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgr020     Document Type: Article
Times cited : (69)

References (52)
  • 1
    • 56649111243 scopus 로고    scopus 로고
    • Cancer in Canada in 2008
    • Marrett,L.D. et al. (2008) Cancer in Canada in 2008. CMAJ, 179, 1163-1170.
    • (2008) CMAJ , vol.179 , pp. 1163-1170
    • Marrett, L.D.1
  • 3
    • 77949953247 scopus 로고    scopus 로고
    • Case-control study of overweight, obesity, and colorectal cancer risk overall and by tumor microsatellite instability status
    • Campbell,P.T. et al. (2010) Case-control study of overweight, obesity, and colorectal cancer risk, overall and by tumor microsatellite instability status. J Natl Cancer Inst, 102, 391-400.
    • (2010) J Natl Cancer Inst , vol.102 , pp. 391-400
    • Campbell, P.T.1
  • 4
    • 10744228074 scopus 로고    scopus 로고
    • Use of 5-fluorouracil and survival in patients with microsatellite-unstable colorectal cancer
    • Carethers,J.M. et al. (2004) Use of 5-fluorouracil and survival in patients with microsatellite-unstable colorectal cancer. Gastroenterology, 126, 394-401.
    • (2004) Gastroenterology , vol.126 , pp. 394-401
    • Carethers, J.M.1
  • 5
    • 0038002279 scopus 로고    scopus 로고
    • Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer
    • Ribic,C.M. et al. (2003) Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer. N Engl J Med, 349, 247-257.
    • (2003) N Engl J Med , vol.349 , pp. 247-257
    • Ribic, C.M.1
  • 6
    • 33745541234 scopus 로고    scopus 로고
    • CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer
    • Weisenberger,D.J. et al. (2006) CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer. Nat Genet, 38, 787-793.
    • (2006) Nat Genet , vol.38 , pp. 787-793
    • Weisenberger, D.J.1
  • 7
    • 33751530490 scopus 로고    scopus 로고
    • Mining the Wnt pathway for cancer therapeutics
    • Barker,N. et al. (2006) Mining the Wnt pathway for cancer therapeutics. Nat Rev Drug Discov, 5, 997-1014.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 997-1014
    • Barker, N.1
  • 8
    • 38949187882 scopus 로고    scopus 로고
    • Tumor formation due to abnormalities in the beta-catenin-independent pathway of Wnt signaling
    • Kikuchi,A. et al. (2008) Tumor formation due to abnormalities in the beta-catenin-independent pathway of Wnt signaling. Cancer Sci, 99, 202-208.
    • (2008) Cancer Sci , vol.99 , pp. 202-208
    • Kikuchi, A.1
  • 9
    • 68849097853 scopus 로고    scopus 로고
    • Wnt/planar cell polarity signaling: a new paradigm for cancer therapy
    • Wang,Y. (2009) Wnt/planar cell polarity signaling: a new paradigm for cancer therapy. Mol Cancer Ther, 8, 2103-2109.
    • (2009) Mol Cancer Ther , vol.8 , pp. 2103-2109
    • Wang, Y.1
  • 10
    • 36949039772 scopus 로고    scopus 로고
    • Frequent epigenetic inactivation of DICKKOPF family genes in human gastrointestinal tumors
    • Sato,H. et al. (2007) Frequent epigenetic inactivation of DICKKOPF family genes in human gastrointestinal tumors. Carcinogenesis, 28, 2459-2466.
    • (2007) Carcinogenesis , vol.28 , pp. 2459-2466
    • Sato, H.1
  • 11
    • 12144291274 scopus 로고    scopus 로고
    • Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer
    • Suzuki,H. et al. (2004) Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer. Nat Genet, 36, 417-422.
    • (2004) Nat Genet , vol.36 , pp. 417-422
    • Suzuki, H.1
  • 12
    • 33745765883 scopus 로고    scopus 로고
    • Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer
    • Aguilera,O. et al. (2006) Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer. Oncogene, 25, 4116-4121.
    • (2006) Oncogene , vol.25 , pp. 4116-4121
    • Aguilera, O.1
  • 13
    • 40849116461 scopus 로고    scopus 로고
    • Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer
    • Suzuki,H. et al. (2008) Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer. Br J Cancer, 98, 1147-1156.
    • (2008) Br J Cancer , vol.98 , pp. 1147-1156
    • Suzuki, H.1
  • 14
    • 49649113673 scopus 로고    scopus 로고
    • Transcriptional silencing of Dickkopf gene family by CpG island hypermethylation in human gastrointestinal cancer
    • Maehata,T. et al. (2008) Transcriptional silencing of Dickkopf gene family by CpG island hypermethylation in human gastrointestinal cancer. World J Gastroenterol, 14, 2702-2714.
    • (2008) World J Gastroenterol , vol.14 , pp. 2702-2714
    • Maehata, T.1
  • 15
    • 46949109354 scopus 로고    scopus 로고
    • Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma
    • Takagi,H. et al. (2008) Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma. J Gastroenterol, 43, 378-389.
    • (2008) J Gastroenterol , vol.43 , pp. 378-389
    • Takagi, H.1
  • 16
    • 23244461593 scopus 로고    scopus 로고
    • Aberrant methylation of secreted frizzled-related protein genes in esophageal adenocarcinoma and Barrett's esophagus
    • Zou,H. et al. (2005) Aberrant methylation of secreted frizzled-related protein genes in esophageal adenocarcinoma and Barrett's esophagus. Int J Cancer, 116, 584-591.
    • (2005) Int J Cancer , vol.116 , pp. 584-591
    • Zou, H.1
  • 17
    • 4444343396 scopus 로고    scopus 로고
    • Expression of the secreted frizzled-related protein gene family is downregulated in human mesothelioma
    • Lee,A.Y. et al. (2004) Expression of the secreted frizzled-related protein gene family is downregulated in human mesothelioma. Oncogene, 23, 6672-6676.
    • (2004) Oncogene , vol.23 , pp. 6672-6676
    • Lee, A.Y.1
  • 18
    • 67349239320 scopus 로고    scopus 로고
    • Epigenetic dysregulation of secreted Frizzled-related proteins in multiple myeloma
    • Jost,E. et al. (2009) Epigenetic dysregulation of secreted Frizzled-related proteins in multiple myeloma. Cancer Lett, 281, 24-31.
    • (2009) Cancer Lett , vol.281 , pp. 24-31
    • Jost, E.1
  • 19
    • 70349311852 scopus 로고    scopus 로고
    • Wnt signaling pathway is epigenetically regulated by methylation of Wnt antagonists in acute myeloid leukemia
    • Valencia,A. et al. (2009) Wnt signaling pathway is epigenetically regulated by methylation of Wnt antagonists in acute myeloid leukemia. Leukemia, 23, 1658-1666.
    • (2009) Leukemia , vol.23 , pp. 1658-1666
    • Valencia, A.1
  • 20
    • 33845778949 scopus 로고    scopus 로고
    • Wnt antagonist family genes as biomarkers for diagnosis, staging, and prognosis of renal cell carcinoma using tumor and serum DNA
    • Urakami,S. et al. (2006) Wnt antagonist family genes as biomarkers for diagnosis, staging, and prognosis of renal cell carcinoma using tumor and serum DNA. Clin Cancer Res, 12, 6989-6997.
    • (2006) Clin Cancer Res , vol.12 , pp. 6989-6997
    • Urakami, S.1
  • 21
    • 48749092367 scopus 로고    scopus 로고
    • Epigenetic inactivation of secreted Frizzled-related proteins in acute myeloid leukaemia
    • Jost,E. et al. (2008) Epigenetic inactivation of secreted Frizzled-related proteins in acute myeloid leukaemia. Br J Haematol, 142, 745-753.
    • (2008) Br J Haematol , vol.142 , pp. 745-753
    • Jost, E.1
  • 22
    • 68349139365 scopus 로고    scopus 로고
    • Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer
    • Veeck,J. et al. (2009) Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer. BMC Cancer, 9, 217.
    • (2009) BMC Cancer , vol.9 , pp. 217
    • Veeck, J.1
  • 23
    • 47249164378 scopus 로고    scopus 로고
    • Epigenetic inactivation of the secreted frizzledrelated protein-5 (SFRP5) gene in human breast cancer is associated with unfavorable prognosis
    • Veeck,J. et al. (2008) Epigenetic inactivation of the secreted frizzledrelated protein-5 (SFRP5) gene in human breast cancer is associated with unfavorable prognosis. Carcinogenesis, 29, 991-998.
    • (2008) Carcinogenesis , vol.29 , pp. 991-998
    • Veeck, J.1
  • 24
    • 77149130202 scopus 로고    scopus 로고
    • Molecular characterization of chronic obstructive pulmonary disease-related non-small cell lung cancer through aberrant methylation and alterations of EGFR signaling
    • Suzuki,M. et al. (2009) Molecular characterization of chronic obstructive pulmonary disease-related non-small cell lung cancer through aberrant methylation and alterations of EGFR signaling. Ann Surg Oncol, 17, 878-888.
    • (2009) Ann Surg Oncol , vol.17 , pp. 878-888
    • Suzuki, M.1
  • 25
    • 35948990450 scopus 로고    scopus 로고
    • Synchronous alterations of Wnt and epidermal growth factor receptor signaling pathways through aberrant methylation and mutation in non small cell lung cancer
    • Suzuki,M. et al. (2007) Synchronous alterations of Wnt and epidermal growth factor receptor signaling pathways through aberrant methylation and mutation in non small cell lung cancer. Clin Cancer Res, 13, 6087-6092.
    • (2007) Clin Cancer Res , vol.13 , pp. 6087-6092
    • Suzuki, M.1
  • 26
    • 33845427638 scopus 로고    scopus 로고
    • Hypermethylation and expression regulation of secreted frizzled-related protein genes in colorectal tumor
    • Qi,J. et al. (2006) Hypermethylation and expression regulation of secreted frizzled-related protein genes in colorectal tumor. World J Gastroenterol, 12, 7113-7117.
    • (2006) World J Gastroenterol , vol.12 , pp. 7113-7117
    • Qi, J.1
  • 27
    • 26444564721 scopus 로고    scopus 로고
    • High frequency of hereditary colorectal cancer in Newfoundland likely involves novel susceptibility genes
    • Woods,M.O. et al. (2005) High frequency of hereditary colorectal cancer in Newfoundland likely involves novel susceptibility genes. Clin Cancer Res, 11, 6853-6861.
    • (2005) Clin Cancer Res , vol.11 , pp. 6853-6861
    • Woods, M.O.1
  • 28
    • 0036613250 scopus 로고    scopus 로고
    • A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer
    • Suzuki,H. et al. (2002) A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer. Nat Genet, 31, 141-149.
    • (2002) Nat Genet , vol.31 , pp. 141-149
    • Suzuki, H.1
  • 29
    • 38849170356 scopus 로고    scopus 로고
    • Colon Cancer Family Registry: an international resource for studies of the genetic epidemiology of colon cancer
    • Newcomb,P.A. et al. (2007) Colon Cancer Family Registry: an international resource for studies of the genetic epidemiology of colon cancer. Cancer Epidemiol Biomarkers Prev, 16, 2331-2343.
    • (2007) Cancer Epidemiol Biomarkers Prev , vol.16 , pp. 2331-2343
    • Newcomb, P.A.1
  • 30
    • 34047272113 scopus 로고    scopus 로고
    • MLH1-93G>A promoter polymorphism and the risk of microsatellite-unstable colorectal cancer
    • Raptis,S. et al. (2007) MLH1-93G>A promoter polymorphism and the risk of microsatellite-unstable colorectal cancer. J Natl Cancer Inst, 99, 463-474.
    • (2007) J Natl Cancer Inst , vol.99 , pp. 463-474
    • Raptis, S.1
  • 31
    • 33847107140 scopus 로고    scopus 로고
    • Very high incidence of familial colorectal cancer in Newfoundland: a comparison with Ontario and 13 other populationbased studies
    • Green,R.C. et al. (2007) Very high incidence of familial colorectal cancer in Newfoundland: a comparison with Ontario and 13 other populationbased studies. Fam Cancer, 6, 53-62.
    • (2007) Fam Cancer , vol.6 , pp. 53-62
    • Green, R.C.1
  • 32
    • 77950655236 scopus 로고    scopus 로고
    • Lynch syndrome-associated breast cancers: clinicopathologic characteristics of a case series from the colon cancer family registry
    • Walsh,M.D. et al. (2010) Lynch syndrome-associated breast cancers: clinicopathologic characteristics of a case series from the colon cancer family registry. Clin Cancer Res, 16, 2214-2224.
    • (2010) Clin Cancer Res , vol.16 , pp. 2214-2224
    • Walsh, M.D.1
  • 33
    • 34547405167 scopus 로고    scopus 로고
    • Incorporation of somatic BRAF mutation testing into an algorithm for the investigation of hereditary non-polyposis colorectal cancer
    • Loughrey,M.B. et al. (2007) Incorporation of somatic BRAF mutation testing into an algorithm for the investigation of hereditary non-polyposis colorectal cancer. Fam Cancer, 6, 301-310.
    • (2007) Fam Cancer , vol.6 , pp. 301-310
    • Loughrey, M.B.1
  • 34
    • 0037083484 scopus 로고    scopus 로고
    • Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumors
    • Lindor,N.M. et al. (2002) Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumors. J Clin Oncol, 20, 1043-1048.
    • (2002) J Clin Oncol , vol.20 , pp. 1043-1048
    • Lindor, N.M.1
  • 35
    • 0034654669 scopus 로고    scopus 로고
    • MethyLight: a high-throughput assay to measure DNA methylation
    • Eads,C.A. et al. (2000) MethyLight: a high-throughput assay to measure DNA methylation. Nucleic Acids Res, 28, E32.
    • (2000) Nucleic Acids Res , vol.28
    • Eads, C.A.1
  • 36
    • 29244490041 scopus 로고    scopus 로고
    • Analysis of repetitive element DNA methylation by MethyLight
    • Weisenberger,D.J. et al. (2005) Analysis of repetitive element DNA methylation by MethyLight. Nucleic Acids Res, 33, 6823-6836.
    • (2005) Nucleic Acids Res , vol.33 , pp. 6823-6836
    • Weisenberger, D.J.1
  • 37
    • 33744550591 scopus 로고    scopus 로고
    • Precision and performance characteristics of bisulfite conversion and real-time PCR (MethyLight) for quantitative DNA methylation analysis
    • Ogino,S. et al. (2006) Precision and performance characteristics of bisulfite conversion and real-time PCR (MethyLight) for quantitative DNA methylation analysis. J Mol Diagn, 8, 209-217.
    • (2006) J Mol Diagn , vol.8 , pp. 209-217
    • Ogino, S.1
  • 38
    • 77956629269 scopus 로고    scopus 로고
    • A characteristic methylation profile in CpG island methylator phenotype-negative distal colorectal cancers
    • An,B. et al. (2010) A characteristic methylation profile in CpG island methylator phenotype-negative distal colorectal cancers. Int J Cancer, 127, 2095-2105.
    • (2010) Int J Cancer , vol.127 , pp. 2095-2105
    • An, B.1
  • 39
    • 34247273521 scopus 로고    scopus 로고
    • Rare CpG island methylator phenotype in ulcerative colitis-associated neoplasias
    • Konishi,K. et al. (2007) Rare CpG island methylator phenotype in ulcerative colitis-associated neoplasias. Gastroenterology, 132, 1254-1260.
    • (2007) Gastroenterology , vol.132 , pp. 1254-1260
    • Konishi, K.1
  • 40
    • 37149041833 scopus 로고    scopus 로고
    • Molecular classification and correlates in colorectal cancer
    • Ogino,S. et al. (2008) Molecular classification and correlates in colorectal cancer. J Mol Diagn, 10, 13-27.
    • (2008) J Mol Diagn , vol.10 , pp. 13-27
    • Ogino, S.1
  • 42
    • 77949759545 scopus 로고    scopus 로고
    • The role of the CpG island methylator phenotype in colorectal cancer prognosis depends on microsatellite instability screening status
    • Dahlin,A.M. et al. (2010) The role of the CpG island methylator phenotype in colorectal cancer prognosis depends on microsatellite instability screening status. Clin Cancer Res, 16, 1845-1855.
    • (2010) Clin Cancer Res , vol.16 , pp. 1845-1855
    • Dahlin, A.M.1
  • 43
    • 20444447557 scopus 로고    scopus 로고
    • Gene expression profiling of microsatellite unstable and microsatellite stable endometrial cancers indicates distinct pathways of aberrant signaling
    • Risinger,J.I. et al. (2005) Gene expression profiling of microsatellite unstable and microsatellite stable endometrial cancers indicates distinct pathways of aberrant signaling. Cancer Res, 65, 5031-5037.
    • (2005) Cancer Res , vol.65 , pp. 5031-5037
    • Risinger, J.I.1
  • 44
    • 42549096546 scopus 로고    scopus 로고
    • Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease
    • Bovolenta,P. et al. (2008) Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease. J Cell Sci, 121, 737-746.
    • (2008) J Cell Sci , vol.121 , pp. 737-746
    • Bovolenta, P.1
  • 45
    • 33845359084 scopus 로고    scopus 로고
    • Function and biological roles of the Dickkopf family of Wnt modulators
    • Niehrs,C. (2006) Function and biological roles of the Dickkopf family of Wnt modulators. Oncogene, 25, 7469-7481.
    • (2006) Oncogene , vol.25 , pp. 7469-7481
    • Niehrs, C.1
  • 46
    • 77953489241 scopus 로고    scopus 로고
    • Colorectal cancers show distinct mutation spectra in members of the canonical WNT signaling pathway according to their anatomical location and type of genetic instability
    • Albuquerque,C. et al. (2010) Colorectal cancers show distinct mutation spectra in members of the canonical WNT signaling pathway according to their anatomical location and type of genetic instability. Genes Chromosomes Cancer, 49, 746-759.
    • (2010) Genes Chromosomes Cancer , vol.49 , pp. 746-759
    • Albuquerque, C.1
  • 47
    • 39749167839 scopus 로고    scopus 로고
    • Differential Wnt pathway gene expression and Ecadherin truncation in sporadic colorectal cancers with and without microsatellite instability
    • Ortega,P. et al. (2008) Differential Wnt pathway gene expression and Ecadherin truncation in sporadic colorectal cancers with and without microsatellite instability. Clin Cancer Res, 14, 995-1001.
    • (2008) Clin Cancer Res , vol.14 , pp. 995-1001
    • Ortega, P.1
  • 48
    • 14644442314 scopus 로고    scopus 로고
    • Genetic and epigenetic changes of components affecting the WNT pathway in colorectal carcinomas stratified by microsatellite instability
    • Thorstensen,L. et al. (2005) Genetic and epigenetic changes of components affecting the WNT pathway in colorectal carcinomas stratified by microsatellite instability. Neoplasia, 7, 99-108.
    • (2005) Neoplasia , vol.7 , pp. 99-108
    • Thorstensen, L.1
  • 49
    • 70349975727 scopus 로고    scopus 로고
    • Down-regulation of frizzled-7 expression decreases survival, invasion and metastatic capabilities of colon cancer cells
    • Ueno,K. et al. (2009) Down-regulation of frizzled-7 expression decreases survival, invasion and metastatic capabilities of colon cancer cells. Br J Cancer, 101, 1374-1381.
    • (2009) Br J Cancer , vol.101 , pp. 1374-1381
    • Ueno, K.1
  • 50
    • 77956167800 scopus 로고    scopus 로고
    • Dishevelled-1 and dishevelled-3 affect cell invasion mainly through canonical and noncanonical Wnt pathway, respectively, and associate with poor prognosis in nonsmall cell lung cancer
    • Zhao,Y. et al. (2010) Dishevelled-1 and dishevelled-3 affect cell invasion mainly through canonical and noncanonical Wnt pathway, respectively, and associate with poor prognosis in nonsmall cell lung cancer. Mol Carcinog, 49, 760-770.
    • (2010) Mol Carcinog , vol.49 , pp. 760-770
    • Zhao, Y.1
  • 51
    • 62849100998 scopus 로고    scopus 로고
    • Canonical and noncanonical Wnt pathway: a comparison among normal ovary, benign ovarian tumor and ovarian cancer
    • Filho,L. et al. (2009) Canonical and noncanonical Wnt pathway: a comparison among normal ovary, benign ovarian tumor and ovarian cancer. Oncology Reports, 21, 313-320.
    • (2009) Oncology Reports , vol.21 , pp. 313-320
    • Filho, L.1
  • 52
    • 77950865388 scopus 로고    scopus 로고
    • Wnt5a signaling is involved in the aggressiveness of prostate cancer and expression of metalloproteinase
    • Yamamoto,H. et al. (2010) Wnt5a signaling is involved in the aggressiveness of prostate cancer and expression of metalloproteinase. Oncogene, 29, 2036-2046.
    • (2010) Oncogene , vol.29 , pp. 2036-2046
    • Yamamoto, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.