Genomic editing opens new avenues for zebrafish as a model for neurodegeneration

Journal of Neurochemistry

Volumn 127, Issue 4, 2013, Pages 461-470

  Schmid, Bettina ^a,c   Haass, Christian ^a,b,c  

^a GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c Munich Cluster for Systems Neurology ^*  (Germany)

Author keywords

CRISPR Cas (clustered regularly interspaced short palindromic repeats); genomics; neurodegeneration; TALEN; zebrafish

Indexed keywords

CAS9 PROTEIN; DEOXYRIBONUCLEASE; DOUBLE STRANDED DNA; FOK1 NUCLEASE; FUSED IN SARCOMA PROTEIN; GUIDE RNA; MESSENGER RNA; PROGRANULIN; TAR DNA BINDING PROTEIN; TARDBPL PROTEIN; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR PROTEIN; UNCLASSIFIED DRUG; ZINC FINGER NUCLEASE;

AMYOTROPHIC LATERAL SCLEROSIS; BASE PAIRING; C9ORF72 GENE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; DISEASE MODEL; DNA CLEAVAGE; DNA END JOINING REPAIR; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVITY; FRONTOTEMPORAL DEMENTIA; GENE; GENE IDENTIFICATION; GENE INACTIVATION; GENE LOCUS; GENE TARGETING; GENETIC ASSOCIATION; GENETIC ENGINEERING; GENETIC MODEL; GENOME; GENOME EDITING; GGGGCC HEXANUCLEOTIDE REPEAT; LOSS OF FUNCTION MUTATION; MOLECULAR CLONING; MOLECULAR RECOGNITION; MOLECULARLY TARGETED THERAPY; MOTONEURON; NERVE DEGENERATION; NERVE FIBER; NONHUMAN; NUCLEOTIDE REPEAT; PHENOTYPE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; REVIEW; ZEBRA FISH; ZINC FINGER MOTIF;

CRISPR/CAS (CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS); GENOMICS; NEURODEGENERATION; TALEN; ZEBRAFISH;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; DEOXYRIBONUCLEASES; DISEASE MODELS, ANIMAL; GENE KNOCK-IN TECHNIQUES; GENE KNOCKOUT TECHNIQUES; GENETIC ENGINEERING; GENOME; HUMANS; NEURODEGENERATIVE DISEASES; ZEBRAFISH; ZINC FINGERS;

DANIO RERIO;

EID: 84887084914     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12460     Document Type: Review

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