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Volumn 74, Issue 2, 2013, Pages 180-187

Loss of function of C9orf72 causes motor deficits in a zebrafish model of amyotrophic lateral sclerosis

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; MESSENGER RNA; MORPHOLINO OLIGONUCLEOTIDE;

EID: 84881531855     PISSN: 03645134     EISSN: 15318249     Source Type: Journal    
DOI: 10.1002/ana.23946     Document Type: Article
Times cited : (263)

References (31)
  • 1
    • 33747605320 scopus 로고    scopus 로고
    • Molecular biology of amyotrophic lateral sclerosis: Insights from genetics
    • Pasinelli P, Brown RH,. Molecular biology of amyotrophic lateral sclerosis: insights from genetics. Nat Rev Neurosci 2006; 7: 710-723.
    • (2006) Nat Rev Neurosci , vol.7 , pp. 710-723
    • Pasinelli, P.1    Brown, R.H.2
  • 3
    • 0037044240 scopus 로고    scopus 로고
    • The overlap of amyotrophic lateral sclerosis and frontotemporal dementia
    • Lomen-Hoerth C, Anderson T, Miller B,. The overlap of amyotrophic lateral sclerosis and frontotemporal dementia. Neurology 2002; 59: 1077-1079.
    • (2002) Neurology , vol.59 , pp. 1077-1079
    • Lomen-Hoerth, C.1    Anderson, T.2    Miller, B.3
  • 4
    • 80052924149 scopus 로고    scopus 로고
    • Motor neuron dysfunction in frontotemporal dementia
    • Burrell JR, Kiernan MC, Vucic S, Hodges JR,. Motor neuron dysfunction in frontotemporal dementia. Brain 2011; 134: 2582-2594.
    • (2011) Brain , vol.134 , pp. 2582-2594
    • Burrell, J.R.1    Kiernan, M.C.2    Vucic, S.3    Hodges, J.R.4
  • 5
    • 23844511513 scopus 로고    scopus 로고
    • Prevalence and patterns of cognitive impairment in sporadic ALS
    • Ringholz GM, Appel SH, Bradshaw M, et al. Prevalence and patterns of cognitive impairment in sporadic ALS. Neurology 2005; 65: 586-590.
    • (2005) Neurology , vol.65 , pp. 586-590
    • Ringholz, G.M.1    Appel, S.H.2    Bradshaw, M.3
  • 6
    • 33749632259 scopus 로고    scopus 로고
    • Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
    • Neumann M, Sampathu DM, Kwong LK, et al. Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science 2006; 314: 130-133.
    • (2006) Science , vol.314 , pp. 130-133
    • Neumann, M.1    Sampathu, D.M.2    Kwong, L.K.3
  • 7
    • 80054832080 scopus 로고    scopus 로고
    • Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS
    • DeJesus-Hernandez M, Mackenzie IR, Boeve BF, et al. Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS. Neuron 2011; 72: 245-256.
    • (2011) Neuron , vol.72 , pp. 245-256
    • Dejesus-Hernandez, M.1    Mackenzie, I.R.2    Boeve, B.F.3
  • 8
    • 80054837386 scopus 로고    scopus 로고
    • A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD
    • Renton AE, Majounie E, Waite A, et al. A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD. Neuron 2011; 72: 257-268.
    • (2011) Neuron , vol.72 , pp. 257-268
    • Renton, A.E.1    Majounie, E.2    Waite, A.3
  • 9
    • 84858622829 scopus 로고    scopus 로고
    • Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: A cross-sectional study
    • Majounie E, Renton AE, Mok K, et al. Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study. Lancet Neurol 2012; 11: 323-330.
    • (2012) Lancet Neurol , vol.11 , pp. 323-330
    • Majounie, E.1    Renton, A.E.2    Mok, K.3
  • 10
    • 84874303411 scopus 로고    scopus 로고
    • C9ORF72 repeat expansions in the frontotemporal dementias spectrum of diseases: A flow-chart for genetic testing
    • Le Ber I, Camuzat A, Guillot-Noel L, et al. C9ORF72 repeat expansions in the frontotemporal dementias spectrum of diseases: a flow-chart for genetic testing. J Alzheimers Dis 2013; 34: 485-499.
    • (2013) J Alzheimers Dis , vol.34 , pp. 485-499
    • Le Ber, I.1    Camuzat, A.2    Guillot-Noel, L.3
  • 11
    • 84864083825 scopus 로고    scopus 로고
    • Phenotype difference between ALS patients with expanded repeats in C9ORF72 and patients with mutations in other ALS-related genes
    • Millecamps S, Boillée S, Le Ber I, et al. Phenotype difference between ALS patients with expanded repeats in C9ORF72 and patients with mutations in other ALS-related genes. J Med Genet 2012; 49: 258-263.
    • (2012) J Med Genet , vol.49 , pp. 258-263
    • Millecamps, S.1    Boillée, S.2    Le Ber, I.3
  • 12
    • 84857054634 scopus 로고    scopus 로고
    • Clinico-pathological features in amyotrophic lateral sclerosis with expansions in C9ORF72
    • Cooper-Knock J, Hewitt C, Highley JR, et al. Clinico-pathological features in amyotrophic lateral sclerosis with expansions in C9ORF72. Brain 2012; 135: 751-764.
    • (2012) Brain , vol.135 , pp. 751-764
    • Cooper-Knock, J.1    Hewitt, C.2    Highley, J.R.3
  • 13
    • 84863393065 scopus 로고    scopus 로고
    • Distinct clinical and pathological characteristics of frontotemporal dementia associated with C9ORF72 mutations
    • Snowden JS, Rollinson S, Thompson JC, et al. Distinct clinical and pathological characteristics of frontotemporal dementia associated with C9ORF72 mutations. Brain 2012; 135: 693-708.
    • (2012) Brain , vol.135 , pp. 693-708
    • Snowden, J.S.1    Rollinson, S.2    Thompson, J.C.3
  • 14
    • 83555166183 scopus 로고    scopus 로고
    • A C9orf72 promoter repeat expansion in a Flanders-Belgian cohort with disorders of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum: A gene identification study
    • Gijselinck I, Van Langenhove T, van der Zee J, et al. A C9orf72 promoter repeat expansion in a Flanders-Belgian cohort with disorders of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum: a gene identification study. Lancet Neurol 2012; 11: 54-65.
    • (2012) Lancet Neurol , vol.11 , pp. 54-65
    • Gijselinck, I.1    Van Langenhove, T.2    Van Der Zee, J.3
  • 15
    • 84874272095 scopus 로고    scopus 로고
    • Unconventional translation of C9ORF72 GGGGCC expansion generates insoluble polypeptides specific to c9FTD/ALS
    • Ash PE, Bieniek KF, Gendron TF, et al. Unconventional translation of C9ORF72 GGGGCC expansion generates insoluble polypeptides specific to c9FTD/ALS. Neuron 2013; 77: 639-646.
    • (2013) Neuron , vol.77 , pp. 639-646
    • Ash, P.E.1    Bieniek, K.F.2    Gendron, T.F.3
  • 16
    • 84874962380 scopus 로고    scopus 로고
    • The C9orf72 GGGGCC repeat is translated into aggregating dipeptide-repeat proteins in FTLD/ALS
    • Mori K, Weng SM, Arzberger T, et al. The C9orf72 GGGGCC repeat is translated into aggregating dipeptide-repeat proteins in FTLD/ALS. Science 2013; 339: 1335-1338.
    • (2013) Science , vol.339 , pp. 1335-1338
    • Mori, K.1    Weng, S.M.2    Arzberger, T.3
  • 17
    • 84864981763 scopus 로고    scopus 로고
    • Advances in understanding the molecular basis of frontotemporal dementia
    • Rademakers R, Neumann M, Mackenzie IR,. Advances in understanding the molecular basis of frontotemporal dementia. Nat Rev Neurol 2012; 8: 423-434.
    • (2012) Nat Rev Neurol , vol.8 , pp. 423-434
    • Rademakers, R.1    Neumann, M.2    Mackenzie, I.R.3
  • 18
    • 84874970790 scopus 로고    scopus 로고
    • Neuroscience. RNA that gets RAN in neurodegeneration
    • Taylor JP,. Neuroscience. RNA that gets RAN in neurodegeneration. Science 2013; 339: 1282-1283.
    • (2013) Science , vol.339 , pp. 1282-1283
    • Taylor, J.P.1
  • 19
    • 38149126474 scopus 로고    scopus 로고
    • High-resolution in situ hybridization to whole-mount zebrafish embryos
    • Thisse C, Thisse B,. High-resolution in situ hybridization to whole-mount zebrafish embryos. Nat Protoc 2008; 3: 59-69.
    • (2008) Nat Protoc , vol.3 , pp. 59-69
    • Thisse, C.1    Thisse, B.2
  • 20
    • 77950360176 scopus 로고    scopus 로고
    • Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo
    • Kabashi E, Lin L, Tradewell ML, et al. Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo. Hum Mol Genet 2010; 19: 671-683.
    • (2010) Hum Mol Genet , vol.19 , pp. 671-683
    • Kabashi, E.1    Lin, L.2    Tradewell, M.L.3
  • 21
    • 80052374038 scopus 로고    scopus 로고
    • FUS and TARDBP but not SOD1 interact in genetic models of amyotrophic lateral sclerosis
    • Kabashi E, Bercier V, Lissouba A, et al. FUS and TARDBP but not SOD1 interact in genetic models of amyotrophic lateral sclerosis. PLoS Genet 2011; 7: e1002214.
    • (2011) PLoS Genet , vol.7
    • Kabashi, E.1    Bercier, V.2    Lissouba, A.3
  • 22
    • 84868656581 scopus 로고    scopus 로고
    • EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans
    • Van Hoecke A, Schoonaert L, Lemmens R, et al. EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans. Nat Med 2012; 18: 1418-1422.
    • (2012) Nat Med , vol.18 , pp. 1418-1422
    • Van Hoecke, A.1    Schoonaert, L.2    Lemmens, R.3
  • 23
    • 84866760281 scopus 로고    scopus 로고
    • Length of normal alleles of C9ORF72 GGGGCC repeat do not influence disease phenotype
    • Rutherford NJ, Heckman MG, Dejesus-Hernandez M, et al. Length of normal alleles of C9ORF72 GGGGCC repeat do not influence disease phenotype. Neurobiol Aging 2012; 33: 2950.e5-e7.
    • (2012) Neurobiol Aging , vol.33
    • Rutherford, N.J.1    Heckman, M.G.2    Dejesus-Hernandez, M.3
  • 24
    • 84876411369 scopus 로고    scopus 로고
    • Large C9orf72 hexanucleotide repeat expansions are seen in multiple neurodegenerative syndromes and are more frequent than expected in the UK population
    • Beck J, Poulter M, Hensman D, et al. Large C9orf72 hexanucleotide repeat expansions are seen in multiple neurodegenerative syndromes and are more frequent than expected in the UK population. Am J Hum Genet 2013; 92: 345-353.
    • (2013) Am J Hum Genet , vol.92 , pp. 345-353
    • Beck, J.1    Poulter, M.2    Hensman, D.3
  • 25
    • 77956850818 scopus 로고    scopus 로고
    • TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia
    • Mackenzie IR, Rademakers R, Neumann M,. TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia. Lancet Neurol 2010; 9: 995-1007.
    • (2010) Lancet Neurol , vol.9 , pp. 995-1007
    • Mackenzie, I.R.1    Rademakers, R.2    Neumann, M.3
  • 26
    • 84155167265 scopus 로고    scopus 로고
    • Gains or losses: Molecular mechanisms of TDP-43-mediated neurodegeneration
    • Lee EB, Lee VM, Trojanowski JQ,. Gains or losses: molecular mechanisms of TDP-43-mediated neurodegeneration. Nat Rev Neurosci 2011; 13: 38-50.
    • (2011) Nat Rev Neurosci , vol.13 , pp. 38-50
    • Lee, E.B.1    Lee, V.M.2    Trojanowski, J.Q.3
  • 27
    • 79953745706 scopus 로고    scopus 로고
    • Repeat associated non-ATG translation initiation: One DNA, two transcripts, seven reading frames, potentially nine toxic entities!
    • Pearson CE,. Repeat associated non-ATG translation initiation: one DNA, two transcripts, seven reading frames, potentially nine toxic entities! PLoS Genet 2011; 7: e1002018.
    • (2011) PLoS Genet , vol.7
    • Pearson, C.E.1
  • 28
    • 84864400774 scopus 로고    scopus 로고
    • Methylene blue protects against TDP-43 and FUS neuronal toxicity in C. Elegans and D. Rerio
    • Vaccaro A, Patten SA, Ciura S, et al. Methylene blue protects against TDP-43 and FUS neuronal toxicity in C. elegans and D. rerio. PLoS One 2012; 7: e42117.
    • (2012) PLoS One , vol.7
    • Vaccaro, A.1    Patten, S.A.2    Ciura, S.3
  • 29
    • 77955089579 scopus 로고    scopus 로고
    • In the swim of things: Recent insights to neurogenetic disorders from zebrafish
    • Kabashi E, Champagne N, Brustein E, Drapeau P,. In the swim of things: recent insights to neurogenetic disorders from zebrafish. Trends Genet 2010; 26: 373-381.
    • (2010) Trends Genet , vol.26 , pp. 373-381
    • Kabashi, E.1    Champagne, N.2    Brustein, E.3    Drapeau, P.4
  • 30
    • 84872719753 scopus 로고    scopus 로고
    • Calcium channel agonists protect against neuromuscular dysfunction in a genetic model of TDP-43 mutation in ALS
    • Armstrong GA, Drapeau P,. Calcium channel agonists protect against neuromuscular dysfunction in a genetic model of TDP-43 mutation in ALS. J Neurosci 2013; 33: 1741-1752.
    • (2013) J Neurosci , vol.33 , pp. 1741-1752
    • Armstrong, G.A.1    Drapeau, P.2
  • 31
    • 84884213153 scopus 로고    scopus 로고
    • Early interneuron dysfunction in ALS: Insights from a mutant sod1 zebrafish model
    • McGown A, McDearmid JR, Panagiotaki N, et al. Early interneuron dysfunction in ALS: insights from a mutant sod1 zebrafish model. Ann Neurol 2013; 73: 246-258.
    • (2013) Ann Neurol , vol.73 , pp. 246-258
    • McGown, A.1    McDearmid, J.R.2    Panagiotaki, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.