Progranulin is neurotrophic in vivo and protects against a mutant TDP-43 induced axonopathy

PLoS ONE

Volumn 5, Issue 10, 2010, Pages

  Laird, Angela S ^a,b   van Hoecke, Annelies ^a,b   De Muynck, Louis ^a,b   Timmers, Mieke ^a,b   van den Bosch, Ludo ^a,b   Van Damme, Philip ^a,b   Robberecht, Wim ^a,b  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; MESSENGER RNA; PROGRANULIN; TAR DNA BINDING PROTEIN; DNA BINDING PROTEIN; GRN PROTEIN, HUMAN; PROTEIN TDP-43; SIGNAL PEPTIDE; SUPEROXIDE DISMUTASE;

5' UNTRANSLATED REGION; ARTICLE; BASE MISPAIRING; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE SEVERITY; EMBRYO; EMBRYO GROWTH; GENE FUNCTION; GENE MUTATION; GENE OVEREXPRESSION; GENETIC LINKAGE; HUMAN VERSUS ANIMAL COMPARISON; IN VIVO STUDY; MOTONEURON; NERVE FIBER GROWTH; NEUROPATHY; NEUROPROTECTION; NEUROTROPISM; NONHUMAN; PHENOTYPE; PROTEIN LOCALIZATION; WILD TYPE; ZEBRA FISH; ANIMAL; GENE SILENCING; GENETICS; HUMAN; MUTATION; NERVE FIBER; PATHOLOGY; PHYSIOLOGY; PRENATAL DEVELOPMENT;

DANIO RERIO;

ANIMALS; AXONS; DNA-BINDING PROTEINS; GENE KNOCKDOWN TECHNIQUES; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MUTATION; SUPEROXIDE DISMUTASE; ZEBRAFISH;

EID: 78149429744     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0013368     Document Type: Article

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