메뉴 건너뛰기




Volumn 28, Issue 5-6, 2013, Pages 287-300

Gene therapy in corneal transplantation

Author keywords

Alternative splicing; Angiogenesis; Graft survival; Immunomodulation; Keratoplasty; Nanotechnology

Indexed keywords

ADENOVIRUS VECTOR; CORTICOSTEROID; CYCLOSPORIN A; DENDRIMER; IMMUNOSUPPRESSIVE AGENT; LENTIVIRUS VECTOR; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; NANOPARTICLE; RAPAMYCIN; TACROLIMUS;

EID: 84886426311     PISSN: 08820538     EISSN: 17445205     Source Type: Journal    
DOI: 10.3109/08820538.2013.825297     Document Type: Review
Times cited : (12)

References (192)
  • 1
    • 84886441306 scopus 로고    scopus 로고
    • 2011-2012 Year in review: Focused on restoring sight worldwide
    • 2011-2012 Year in Review: Focused on Restoring Sight Worldwide. Eye Bank Association of America 2012;1-13. Available at: http://issuu.com/moiremarketing/ docs/ebaa-2011-12yir-final?e=1631814/2738036
    • (2012) Eye Bank Association of America , pp. 1-13
  • 2
    • 0037625215 scopus 로고    scopus 로고
    • Long-term graft survival after penetrating keratoplasty
    • Thompson Jr RW, Price MO, Bowers PJ, et al. Long-term graft survival after penetrating keratoplasty. Ophthalmology 2003;110:1396-1402.
    • (2003) Ophthalmology , vol.110 , pp. 1396-1402
    • Thompson Jr., R.W.1    Price, M.O.2    Bowers, P.J.3
  • 3
    • 0025299379 scopus 로고
    • Immune privilege and immune regulation in the eye
    • Niederkorn JY. Immune privilege and immune regulation in the eye. Adv Immunol 1990;48:191-226.
    • (1990) Adv Immunol , vol.48 , pp. 191-226
    • Niederkorn, J.Y.1
  • 4
    • 58849097203 scopus 로고    scopus 로고
    • Risk factors for human corneal graft failure within the Australian corneal graft registry
    • Williams KA, Lowe M, Bartlett C, et al. Risk factors for human corneal graft failure within the Australian corneal graft registry. Transplantation 2008;86:1720-1724.
    • (2008) Transplantation , vol.86 , pp. 1720-1724
    • Williams, K.A.1    Lowe, M.2    Bartlett, C.3
  • 5
    • 84873726155 scopus 로고    scopus 로고
    • Long-term rejection incidence and reversibility after penetrating and lamellar keratoplasty
    • Guilbert E, Bullet J, Sandali O, et al. Long-term rejection incidence and reversibility after penetrating and lamellar keratoplasty. Am J Ophthalmol 2013;155:560-569.
    • (2013) Am J Ophthalmol , vol.155 , pp. 560-569
    • Guilbert, E.1    Bullet, J.2    Sandali, O.3
  • 6
    • 0033135940 scopus 로고    scopus 로고
    • Anterior chamber-associated immune deviation, ocular immune privilege, and orthotopic corneal allografts
    • Streilein JW, Yamada J, Dana MR, et al. Anterior chamber-associated immune deviation, ocular immune privilege, and orthotopic corneal allografts. Transplant Proc 1999;31: 1472-1475.
    • (1999) Transplant Proc , vol.31 , pp. 1472-1475
    • Streilein, J.W.1    Yamada, J.2    Dana, M.R.3
  • 7
    • 0019423220 scopus 로고
    • Clinical types of corneal transplant rejection: Their manifestations, frequency, pre-operative correlates, and treatment
    • Alldredge OC, Krachmer JH. Clinical types of corneal transplant rejection: their manifestations, frequency, pre-operative correlates, and treatment. Arch Ophthalmol 1981; 99:599-604.
    • (1981) Arch Ophthalmol , vol.99 , pp. 599-604
    • Alldredge, O.C.1    Krachmer, J.H.2
  • 8
    • 16244401628 scopus 로고    scopus 로고
    • Trends and results for organ donation and transplantation in the United States 2004
    • Port FK, Dykstra DM, Merion RM, et al. Trends and results for organ donation and transplantation in the United States, 2004. Am J Transplant 2005;5:843-849.
    • (2005) Am J Transplant , vol.5 , pp. 843-849
    • Port, F.K.1    Dykstra, D.M.2    Merion, R.M.3
  • 9
    • 84886446130 scopus 로고    scopus 로고
    • Immunologically high-risk penetrating keratoplasty
    • Krachmer J, Mannis, MJ, Jolland, EJ, eds. St. Louis: Mosby
    • Hamrah P, Mantopoulos, D, Akhtar, J, Djalilian, AR. Immunologically high-risk penetrating keratoplasty. In: Cornea, 3rd ed. Krachmer J, Mannis, MJ, Jolland, EJ, eds. St. Louis: Mosby, 2010. pp 1495-1510.
    • (2010) Cornea, 3rd Ed , pp. 1495-1510
    • Hamrah, P.1    Mantopoulos, D.2    Akhtar, J.3    Djalilian, A.R.4
  • 10
    • 51849097838 scopus 로고    scopus 로고
    • Clinical and experimental research of corneal lymphangiogenesis after keratoplasty
    • Ling S, Lin H, Xiang D, et al. Clinical and experimental research of corneal lymphangiogenesis after keratoplasty. Ophthalmologica 2008;222:308-316.
    • (2008) Ophthalmologica , vol.222 , pp. 308-316
    • Ling, S.1    Lin, H.2    Xiang, D.3
  • 11
    • 3242881656 scopus 로고    scopus 로고
    • Inhibition of hemangiogenesis and lymphangiogenesis after normal-risk corneal transplantation by neutralizing VEGF promotes graft survival
    • Cursiefen C, Cao J, Chen L, et al. Inhibition of hemangiogenesis and lymphangiogenesis after normal-risk corneal transplantation by neutralizing VEGF promotes graft survival. Invest Ophthalmol Vis Sci 2004;45: 2666-2673.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 2666-2673
    • Cursiefen, C.1    Cao, J.2    Chen, L.3
  • 12
    • 68049098957 scopus 로고    scopus 로고
    • Transient postoperative vascular endothelial growth factor (VEGF)-neutralisation improves graft survival in corneas with partly regressed inflammatory neovascularisation
    • Bachmann BO, Luetjen-Drecoll E, Bock F, et al. Transient postoperative vascular endothelial growth factor (VEGF)-neutralisation improves graft survival in corneas with partly regressed inflammatory neovascularisation. Br J Ophthalmol 2009;93:1075-1080.
    • (2009) Br J Ophthalmol , vol.93 , pp. 1075-1080
    • Bachmann, B.O.1    Luetjen-Drecoll, E.2    Bock, F.3
  • 13
    • 44649193281 scopus 로고    scopus 로고
    • Inflammatory corneal (lymph)angiogenesis is blocked by VEGFR-tyrosine kinase inhibitor ZK 261, 991, resulting in improved graft survival after corneal transplantation
    • Hos D, Bock F, Dietrich T, et al. Inflammatory corneal (lymph)angiogenesis is blocked by VEGFR-tyrosine kinase inhibitor ZK 261, 991, resulting in improved graft survival after corneal transplantation. Invest Ophthalmol Vis Sci 2008; 49:1836-1842.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 1836-1842
    • Hos, D.1    Bock, F.2    Dietrich, T.3
  • 14
    • 77954349323 scopus 로고    scopus 로고
    • Corneal neovascular-ization as a risk factor for graft failure and rejection after keratoplasty: An evidence-based meta-analysis
    • Bachmann B, Taylor RS, Cursiefen C. Corneal neovascular-ization as a risk factor for graft failure and rejection after keratoplasty: an evidence-based meta-analysis. Ophthalmology 2010;117:1300-1305.
    • (2010) Ophthalmology , vol.117 , pp. 1300-1305
    • Bachmann, B.1    Taylor, R.S.2    Cursiefen, C.3
  • 15
    • 0029802472 scopus 로고    scopus 로고
    • Loss and restoration of immune privilege in eyes with corneal neovascularization
    • Dana MR, Streilein JW. Loss and restoration of immune privilege in eyes with corneal neovascularization. Invest Ophthalmol Vis Sci 1996;37:2485-2494.
    • (1996) Invest Ophthalmol Vis Sci , vol.37 , pp. 2485-2494
    • Dana, M.R.1    Streilein, J.W.2
  • 16
    • 33646949958 scopus 로고    scopus 로고
    • Angiogenesis and lymphangiogenesis-implications for corneal immunity
    • Dana MR. Angiogenesis and lymphangiogenesis-implications for corneal immunity. Semin Ophthalmol 2006;21:19-22.
    • (2006) Semin Ophthalmol , vol.21 , pp. 19-22
    • Dana, M.R.1
  • 17
    • 70349923364 scopus 로고    scopus 로고
    • Michael Edelstein, John Wiley and Sons Ltd
    • Michael Edelstein. Gene Therapy Clinical Trials Worldwide; John Wiley and Sons Ltd., 2012. Available at: http://www.abedia.com/wiley/search-results.php? TrialCountry=&RefResults=& CategoryMain=Oculardiseases&Indication= &Vector=& Genes=&GeneTypes=&Phase=&Status= &FinalApprYear= &Submit=%A0%A0Search%A0%A0
    • (2012) Gene Therapy Clinical Trials Worldwide
  • 18
    • 84874346554 scopus 로고    scopus 로고
    • Gene therapy clinical trials worldwide to 2012: An update
    • Ginn SL, Alexander IE, Edelstein ML, et al. Gene therapy clinical trials worldwide to 2012: an update. J Gene Med 2013;15:65-77.
    • (2013) J Gene Med , vol.15 , pp. 65-77
    • Ginn, S.L.1    Alexander, I.E.2    Edelstein, M.L.3
  • 19
    • 84860492238 scopus 로고    scopus 로고
    • Role of lentivirus-mediated overexpression of programmed death-ligand 1 on corneal allograft survival
    • Nosov M, Wilk M, Morcos M, et al. Role of lentivirus-mediated overexpression of programmed death-ligand 1 on corneal allograft survival. Am J Transplant 2012;12: 1313-1322.
    • (2012) Am J Transplant , vol.12 , pp. 1313-1322
    • Nosov, M.1    Wilk, M.2    Morcos, M.3
  • 20
    • 33847776096 scopus 로고    scopus 로고
    • Effects of local and systemic viral interleukin-10 gene transfer on corneal allograft survival
    • Gong N, Pleyer U, Volk HD, et al. Effects of local and systemic viral interleukin-10 gene transfer on corneal allograft survival. Gene Ther 2007;14:484-490.
    • (2007) Gene Ther , vol.14 , pp. 484-490
    • Gong, N.1    Pleyer, U.2    Volk, H.D.3
  • 21
    • 84859851580 scopus 로고    scopus 로고
    • Corneal transduc-tion by intra-stromal injection of AAV vectors in vivo in the mouse and ex vivo in human explants
    • Hippert C, Ibanes S, Serratrice N, et al. Corneal transduc-tion by intra-stromal injection of AAV vectors in vivo in the mouse and ex vivo in human explants. PLoS One 2012;7: e35318.
    • (2012) PLoS One , vol.7
    • Hippert, C.1    Ibanes, S.2    Serratrice, N.3
  • 22
    • 3142651910 scopus 로고    scopus 로고
    • In vivo gene delivery and visualization of corneal stromal cells using an adenoviral vector and keratocyte-specific promoter
    • Carlson EC, Liu CY, Yang X, et al. In vivo gene delivery and visualization of corneal stromal cells using an adenoviral vector and keratocyte-specific promoter. Invest Ophthalmol Vis Sci 2004;45:2194-2200.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 2194-2200
    • Carlson, E.C.1    Liu, C.Y.2    Yang, X.3
  • 23
    • 43049124189 scopus 로고    scopus 로고
    • Graft failure IV. Immunologic mechanisms of corneal transplant rejection
    • Chong EM, Dana MR. Graft failure IV. Immunologic mechanisms of corneal transplant rejection. Int Ophthalmol 2008;28:209-222.
    • (2008) Int Ophthalmol , vol.28 , pp. 209-222
    • Chong, E.M.1    Dana, M.R.2
  • 24
    • 0032855582 scopus 로고    scopus 로고
    • Immunobiology and immunopathology of corneal transplantation
    • Streilein JW. Immunobiology and immunopathology of corneal transplantation. Chem Immunol 1999;73:186-206.
    • (1999) Chem Immunol , vol.73 , pp. 186-206
    • Streilein, J.W.1
  • 25
    • 0031470483 scopus 로고    scopus 로고
    • Induction of anterior chamber-associated immune deviation by corneal allografts placed in the anterior chamber
    • Yamada J, Streilein JW. Induction of anterior chamber-associated immune deviation by corneal allografts placed in the anterior chamber. Invest Ophthalmol Vis Sci 1997;38: 2833-2843.
    • (1997) Invest Ophthalmol Vis Sci , vol.38 , pp. 2833-2843
    • Yamada, J.1    Streilein, J.W.2
  • 26
    • 0037308521 scopus 로고    scopus 로고
    • The corneal stroma is endowed with a significant number of resident dendritic cells
    • Hamrah P, Liu Y, Zhang Q, et al. The corneal stroma is endowed with a significant number of resident dendritic cells. Invest Ophthalmol Vis Sci 2003;44:581-589.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 581-589
    • Hamrah, P.1    Liu, Y.2    Zhang, Q.3
  • 27
    • 0036190564 scopus 로고    scopus 로고
    • Novel characterization of MHC class II-negative population of resident corneal Langerhans cell-type dendritic cells
    • Hamrah P, Zhang Q, Liu Y, et al. Novel characterization of MHC class II-negative population of resident corneal Langerhans cell-type dendritic cells. Invest Ophthalmol Vis Sci 2002;43:639-646.
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , pp. 639-646
    • Hamrah, P.1    Zhang, Q.2    Liu, Y.3
  • 28
    • 84886435093 scopus 로고    scopus 로고
    • Trafficking of immune cells in the cornea and ocular surface Advances in Ophthalmology
    • Rumelt S, ed
    • Qazi Y, Turhan, A, Hamrah, P. Trafficking of immune cells in the cornea and ocular surface. In: Advances in Ophthalmology. Rumelt S, ed. Rijeka: InTech, 2012. pp 79-104.
    • (2012) Rijeka: InTech , pp. 79-104
    • Qazi, Y.1    Turhan, A.2    Hamrah, P.3
  • 29
    • 0030716516 scopus 로고    scopus 로고
    • Role of Fas-Fas ligand interactions in the immunorejection of allogeneic mouse corneal transplants
    • Yamagami S, Kawashima H, Tsuru T, et al. Role of Fas-Fas ligand interactions in the immunorejection of allogeneic mouse corneal transplants. Transplantation 1997;64: 1107-1111.
    • (1997) Transplantation , vol.64 , pp. 1107-1111
    • Yamagami, S.1    Kawashima, H.2    Tsuru, T.3
  • 30
    • 0030821649 scopus 로고    scopus 로고
    • CD95 ligand (FasL)-induced apoptosis is necessary for corneal allograft survival
    • Stuart PM, Griffith TS, Usui N, et al. CD95 ligand (FasL)-induced apoptosis is necessary for corneal allograft survival. J Clin Invest 1997;99:396-402.
    • (1997) J Clin Invest , vol.99 , pp. 396-402
    • Stuart, P.M.1    Griffith, T.S.2    Usui, N.3
  • 31
    • 84880109083 scopus 로고    scopus 로고
    • PD-L1/PD-1 co-stimulation, a brake for T cell activation and a T cell differentiation signal
    • Liechtenstein T, Dufait I, Bricogne C, et al. PD-L1/PD-1 co-stimulation, a brake for T cell activation and a T cell differentiation signal. J Clin Cell Immunol 2012;S12:006.
    • (2012) J Clin Cell Immunol , vol.S12 , pp. 006
    • Liechtenstein, T.1    Dufait, I.2    Bricogne, C.3
  • 32
    • 35748972357 scopus 로고    scopus 로고
    • The function of donor versus recipient programmed death-ligand 1 in corneal allograft survival
    • Shen L, Jin Y, Freeman GJ, et al. The function of donor versus recipient programmed death-ligand 1 in corneal allograft survival. J Immunol 2007;179:3672-3679.
    • (2007) J Immunol , vol.179 , pp. 3672-3679
    • Shen, L.1    Jin, Y.2    Freeman, G.J.3
  • 33
    • 58249085915 scopus 로고    scopus 로고
    • PD-L1 expression on human ocular cells and its possible role in regulating immune-mediated ocular inflammation
    • Yang W, Li H, Chen PW, et al. PD-L1 expression on human ocular cells and its possible role in regulating immune-mediated ocular inflammation. Invest Ophthalmol Vis Sci 2009;50:273-280.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 273-280
    • Yang, W.1    Li, H.2    Chen, P.W.3
  • 34
    • 84870945643 scopus 로고    scopus 로고
    • PD-1 inhibits T cell proliferation by upregulating p27 and p15 and suppressing Cdc25A
    • Patsoukis N, Sari D, Boussiotis VA. PD-1 inhibits T cell proliferation by upregulating p27 and p15 and suppressing Cdc25A. Cell Cycle 2012;11:4305-4309.
    • (2012) Cell Cycle , vol.11 , pp. 4305-4309
    • Patsoukis, N.1    Sari, D.2    Boussiotis, V.A.3
  • 35
    • 56949106507 scopus 로고    scopus 로고
    • Splenic CD8 T cells secrete TGF-beta1 to exert suppression in mice with anterior chamber-associated immune deviation
    • Jiang L, He H, Yang P, et al. Splenic CD8 T cells secrete TGF-beta1 to exert suppression in mice with anterior chamber-associated immune deviation. Graefes Arch Clin Exp Ophthalmol 2009;247:87-92.
    • (2009) Graefes Arch Clin Exp Ophthalmol , vol.247 , pp. 87-92
    • Jiang, L.1    He, H.2    Yang, P.3
  • 36
    • 0035997383 scopus 로고    scopus 로고
    • Anterior chamber associated immune deviation (ACAID): Regulation, biological relevance, and implications for therapy
    • Stein-Streilein J, Streilein JW. Anterior chamber associated immune deviation (ACAID): regulation, biological relevance, and implications for therapy. Int Rev Immunol 2002; 21:123-152.
    • (2002) Int Rev Immunol , vol.21 , pp. 123-152
    • Stein-Streilein, J.1    Streilein, J.W.2
  • 37
    • 0025791004 scopus 로고
    • Studies on the induction of anterior chamber-associated immune deviation (ACAID). 1. Evidence that an antigen-specific, ACAID-inducing, cell-associated signal exists in the peripheral blood
    • Wilbanks GA, Streilein JW. Studies on the induction of anterior chamber-associated immune deviation (ACAID). 1. Evidence that an antigen-specific, ACAID-inducing, cell-associated signal exists in the peripheral blood. J Immunol 1991;146:2610-2617.
    • (1991) J Immunol , vol.146 , pp. 2610-2617
    • Wilbanks, G.A.1    Streilein, J.W.2
  • 38
    • 0017333928 scopus 로고
    • Immune response to immunization via the anterior chamber of the eye. I. F. Lymphocyte-induced immune deviation
    • Kaplan HJ, Streilein JW. Immune response to immunization via the anterior chamber of the eye. I. F. lymphocyte-induced immune deviation. J Immunol 1977; 118:809-814.
    • (1977) J Immunol , vol.118 , pp. 809-814
    • Kaplan, H.J.1    Streilein, J.W.2
  • 39
    • 0017813457 scopus 로고
    • Immune response to immunization via the anterior chamber of the eye. II. An analysis of F1 lymphocyte-induced immune deviation
    • Kaplan HJ, Streilein JW. Immune response to immunization via the anterior chamber of the eye. II. An analysis of F1 lymphocyte-induced immune deviation. J Immunol 1978;120:689-693.
    • (1978) J Immunol , vol.120 , pp. 689-693
    • Kaplan, H.J.1    Streilein, J.W.2
  • 40
    • 0025179293 scopus 로고
    • Anterior chamber associated immune deviation: The privilege of immunity in the eye
    • Streilein JW. Anterior chamber associated immune deviation: the privilege of immunity in the eye. Surv Ophthalmol 1990;35:67-73.
    • (1990) Surv Ophthalmol , vol.35 , pp. 67-73
    • Streilein, J.W.1
  • 41
    • 0031050739 scopus 로고    scopus 로고
    • Correlation of anterior chamber-associated immune deviation with suppression of corneal epithelial rejection in mice
    • Yao YF, Inoue Y, Miyazaki D, et al. Correlation of anterior chamber-associated immune deviation with suppression of corneal epithelial rejection in mice. Invest Ophthalmol Vis Sci 1997;38:292-300.
    • (1997) Invest Ophthalmol Vis Sci , vol.38 , pp. 292-300
    • Yao, Y.F.1    Inoue, Y.2    Miyazaki, D.3
  • 42
    • 77349087851 scopus 로고    scopus 로고
    • Dendritic cell physiology and function in the eye
    • Forrester JV, Xu H, Kuffova L, et al. Dendritic cell physiology and function in the eye. Immunol Rev 2010; 234:282-304.
    • (2010) Immunol Rev , vol.234 , pp. 282-304
    • Forrester, J.V.1    Xu, H.2    Kuffova, L.3
  • 43
    • 0037497493 scopus 로고    scopus 로고
    • Alterations in corneal stromal dendritic cell phenotype and distribution in inflammation
    • Hamrah P, Liu Y, Zhang Q, et al. Alterations in corneal stromal dendritic cell phenotype and distribution in inflammation. Arch Ophthalmol 2003;121:1132-1140.
    • (2003) Arch Ophthalmol , vol.121 , pp. 1132-1140
    • Hamrah, P.1    Liu, Y.2    Zhang, Q.3
  • 44
    • 0037148515 scopus 로고    scopus 로고
    • Draining lymph nodes of corneal transplant hosts exhibit evidence for donor major histocompatibility complex (MHC) class II-positive dendritic cells derived from MHC class II-negative grafts
    • Liu Y, Hamrah P, Zhang Q, et al. Draining lymph nodes of corneal transplant hosts exhibit evidence for donor major histocompatibility complex (MHC) class II-positive dendritic cells derived from MHC class II-negative grafts. J Exp Med 2002;195:259-268.
    • (2002) J Exp Med , vol.195 , pp. 259-268
    • Liu, Y.1    Hamrah, P.2    Zhang, Q.3
  • 45
    • 84874977195 scopus 로고    scopus 로고
    • Dendritic cell modification as a route to inhibiting corneal graft rejection by the indirect pathway of allorecognition
    • Khan A, Fu H, Tan LA, et al. Dendritic cell modification as a route to inhibiting corneal graft rejection by the indirect pathway of allorecognition. Eur J Immunol 2012;43:734-746.
    • (2012) Eur J Immunol , vol.43 , pp. 734-746
    • Khan, A.1    Fu, H.2    Tan, L.A.3
  • 46
    • 34547829459 scopus 로고    scopus 로고
    • Corneal graft rejection is accompanied by apoptosis of the endothelium and is prevented by gene therapy with bcl-xL
    • Barcia RN, Dana MR, Kazlauskas A. Corneal graft rejection is accompanied by apoptosis of the endothelium and is prevented by gene therapy with bcl-xL. Am J Transplant 2007;7:2082-2089.
    • (2007) Am J Transplant , vol.7 , pp. 2082-2089
    • Barcia, R.N.1    Dana, M.R.2    Kazlauskas, A.3
  • 47
    • 0035838984 scopus 로고    scopus 로고
    • Dendritic cells: Specialized and regulated antigen processing machines
    • Mellman I, Steinman RM. Dendritic cells: specialized and regulated antigen processing machines. Cell 2001;106: 255-258.
    • (2001) Cell , vol.106 , pp. 255-258
    • Mellman, I.1    Steinman, R.M.2
  • 48
    • 4644225146 scopus 로고    scopus 로고
    • Relevance of the direct pathway of sensitization in corneal transplantation is dictated by the graft bed microenvironment
    • Huq S, Liu Y, Benichou G, et al. Relevance of the direct pathway of sensitization in corneal transplantation is dictated by the graft bed microenvironment. J Immunol 2004;173:4464-4469.
    • (2004) J Immunol , vol.173 , pp. 4464-4469
    • Huq, S.1    Liu, Y.2    Benichou, G.3
  • 49
    • 58949097413 scopus 로고    scopus 로고
    • Differential roles of direct and indirect allorecognition pathways in the rejection of skin and corneal transplants
    • Boisgerault F, Liu Y, Anosova N, et al. Differential roles of direct and indirect allorecognition pathways in the rejection of skin and corneal transplants. Transplantation 2009; 87:16-23.
    • (2009) Transplantation , vol.87 , pp. 16-23
    • Boisgerault, F.1    Liu, Y.2    Anosova, N.3
  • 50
    • 0034059575 scopus 로고    scopus 로고
    • Langerhans cells, orthotopic corneal allografts, and direct and indirect pathways of T-cell allorecognition
    • Sano Y, Ksander BR, Streilein JW. Langerhans cells, orthotopic corneal allografts, and direct and indirect pathways of T-cell allorecognition. Invest Ophthalmol Vis Sci 2000;41:1422-1431.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 1422-1431
    • Sano, Y.1    Ksander, B.R.2    Streilein, J.W.3
  • 51
    • 38449117237 scopus 로고    scopus 로고
    • The immunobiology of corneal transplantation
    • Williams KA, Coster DJ. The immunobiology of corneal transplantation. Transplantation 2007;84:806-813.
    • (2007) Transplantation , vol.84 , pp. 806-813
    • Williams, K.A.1    Coster, D.J.2
  • 52
    • 0033822708 scopus 로고    scopus 로고
    • Twenty-five-year panorama of corneal immunology: Emerging concepts in the immu-nopathogenesis of microbial keratitis, peripheral ulcerative keratitis, and corneal transplant rejection
    • Dana MR, Qian Y, Hamrah P. Twenty-five-year panorama of corneal immunology: emerging concepts in the immu-nopathogenesis of microbial keratitis, peripheral ulcerative keratitis, and corneal transplant rejection. Cornea 2000;19: 625-643.
    • (2000) Cornea , vol.19 , pp. 625-643
    • Dana, M.R.1    Qian, Y.2    Hamrah, P.3
  • 53
    • 0141652012 scopus 로고    scopus 로고
    • Role of resident corneal leukocytes and draining cervical lymph nodes in corneal allograft rejection
    • Yamagami S, Amano S. Role of resident corneal leukocytes and draining cervical lymph nodes in corneal allograft rejection. Cornea 2003;22:S61-65.
    • (2003) Cornea , vol.22
    • Yamagami, S.1    Amano, S.2
  • 54
    • 0033570003 scopus 로고    scopus 로고
    • Detection of minor alloantigen-specific cytotoxic T cells after rejection of murine orthotopic corneal allografts: Evidence that graft antigens are recognized exclusively via the "indirect pathway"
    • Sano Y, Streilein JW, Ksander BR. Detection of minor alloantigen-specific cytotoxic T cells after rejection of murine orthotopic corneal allografts: evidence that graft antigens are recognized exclusively via the "indirect pathway". Transplantation 1999;68:963-970.
    • (1999) Transplantation , vol.68 , pp. 963-970
    • Sano, Y.1    Streilein, J.W.2    Ksander, B.R.3
  • 55
    • 0032730575 scopus 로고    scopus 로고
    • Differential chemokine gene expression in corneal transplant rejection
    • Yamagami S, Miyazaki D, Ono SJ, et al. Differential chemokine gene expression in corneal transplant rejection. Invest Ophthalmol Vis Sci 1999;40:2892-2897.
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , pp. 2892-2897
    • Yamagami, S.1    Miyazaki, D.2    Ono, S.J.3
  • 56
    • 26244456419 scopus 로고    scopus 로고
    • Early ocular chemokine gene expression and leukocyte infiltration after high-risk corneal transplantation
    • Yamagami S, Hamrah P, Zhang Q, et al. Early ocular chemokine gene expression and leukocyte infiltration after high-risk corneal transplantation. Mol Vis 2005;11:632-640.
    • (2005) Mol Vis , vol.11 , pp. 632-640
    • Yamagami, S.1    Hamrah, P.2    Zhang, Q.3
  • 57
    • 0034720057 scopus 로고    scopus 로고
    • Characterization of cyto-kine profiles in corneal allograft with anti-adhesion therapy
    • Yamagami S, Isobe M, Tsuru T. Characterization of cyto-kine profiles in corneal allograft with anti-adhesion therapy. Transplantation 2000;69:1655-1659.
    • (2000) Transplantation , vol.69 , pp. 1655-1659
    • Yamagami, S.1    Isobe, M.2    Tsuru, T.3
  • 58
    • 0033770794 scopus 로고    scopus 로고
    • The role of cytotoxic T lymphocytes in corneal allograft rejection
    • Hegde S, Niederkorn JY. The role of cytotoxic T lymphocytes in corneal allograft rejection. Invest Ophthalmol Vis Sci 2000;41:3341-3347.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 3341-3347
    • Hegde, S.1    Niederkorn, J.Y.2
  • 59
    • 0035142634 scopus 로고    scopus 로고
    • Cytotoxic T cells play no essential role in acute rejection of orthotopic corneal allografts in mice
    • Yamada J, Ksander BR, Streilein JW. Cytotoxic T cells play no essential role in acute rejection of orthotopic corneal allografts in mice. Invest Ophthalmol Vis Sci 2001;42: 386-392.
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , pp. 386-392
    • Yamada, J.1    Ksander, B.R.2    Streilein, J.W.3
  • 60
    • 12344251710 scopus 로고    scopus 로고
    • CD4() T-cell-mediated mechanisms of corneal allograft rejection: Role of Fas-induced apoptosis
    • Hegde S, Beauregard C, Mayhew E, et al. CD4() T-cell-mediated mechanisms of corneal allograft rejection: role of Fas-induced apoptosis. Transplantation 2005;79:23-31.
    • (2005) Transplantation , vol.79 , pp. 23-31
    • Hegde, S.1    Beauregard, C.2    Mayhew, E.3
  • 61
    • 17844371993 scopus 로고    scopus 로고
    • Immunosuppression with cyclosporine A and mycophe-nolate mofetil after penetrating high-risk keratoplasty: A retrospective study
    • Birnbaum F, Bohringer D, Sokolovska Y, et al. Immunosuppression with cyclosporine A and mycophe-nolate mofetil after penetrating high-risk keratoplasty: a retrospective study. Transplantation 2005;79:964-968.
    • (2005) Transplantation , vol.79 , pp. 964-968
    • Birnbaum, F.1    Bohringer, D.2    Sokolovska, Y.3
  • 62
    • 62549111284 scopus 로고    scopus 로고
    • Case-control study of subconjunctival triamcinolone acetonide injection vs intravenous methylprednisolone pulse in the treatment of endothelial corneal allograft rejection
    • Costa DC, de Castro RS, Kara-Jose N. Case-control study of subconjunctival triamcinolone acetonide injection vs intravenous methylprednisolone pulse in the treatment of endothelial corneal allograft rejection. Eye (Lond) 2009;23: 708-714.
    • (2009) Eye (Lond) , vol.23 , pp. 708-714
    • Costa, D.C.1    De Castro, R.S.2    Kara-Jose, N.3
  • 63
    • 84886422503 scopus 로고    scopus 로고
    • Immunotherapy of ocular surface diseases and graft rejection
    • Copland R, Afshari, NA, eds. New Delhi: Jaypee Brothers
    • Yamaguchi T, Hamrah, P. Immunotherapy of ocular surface diseases and graft rejection. In: Copland and Afshari's Principles and Practice of Cornea. Copland R, Afshari, NA, eds. New Delhi: Jaypee Brothers, 2013. pp 580-600.
    • (2013) Copland and Afshari's Principles and Practice of Cornea , pp. 580-600
    • Yamaguchi, T.1    Hamrah, P.2
  • 64
    • 84890133219 scopus 로고    scopus 로고
    • The effect of different doses of subconjunctival bevacizumab injection on corneal neovascularization
    • Acar BT, Halili E, Acar S. The effect of different doses of subconjunctival bevacizumab injection on corneal neovascularization. Int Ophthalmol 2013.
    • (2013) Int Ophthalmol
    • Acar, B.T.1    Halili, E.2    Acar, S.3
  • 65
    • 84872272757 scopus 로고    scopus 로고
    • Subconjunctival bevacizumab induces regression of corneal neovascular-isation: A pilot randomised placebo-controlled double-masked trial
    • Petsoglou C, Balaggan KS, Dart JK, et al. Subconjunctival bevacizumab induces regression of corneal neovascular-isation: a pilot randomised placebo-controlled double-masked trial. Br J Ophthalmol 2013;97:28-32.
    • (2013) Br J Ophthalmol , vol.97 , pp. 28-32
    • Petsoglou, C.1    Balaggan, K.S.2    Dart, J.K.3
  • 66
    • 80052782941 scopus 로고    scopus 로고
    • Compensatory growth factor and cytokine response in tears after subconjunctival bevacizumab injection
    • Jeong JH, Chun YS, Kim ES, et al. Compensatory growth factor and cytokine response in tears after subconjunctival bevacizumab injection. Cornea 2011;30:1071-1077.
    • (2011) Cornea , vol.30 , pp. 1071-1077
    • Jeong, J.H.1    Chun, Y.S.2    Kim, E.S.3
  • 67
    • 77952514423 scopus 로고    scopus 로고
    • Effects of topical and subconjunctival bevacizumab in high-risk corneal transplant survival
    • Dastjerdi MH, Saban DR, Okanobo A, et al. Effects of topical and subconjunctival bevacizumab in high-risk corneal transplant survival. Invest Ophthalmol Vis Sci 2010; 51:2411-2417.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 2411-2417
    • Dastjerdi, M.H.1    Saban, D.R.2    Okanobo, A.3
  • 68
    • 78649832445 scopus 로고    scopus 로고
    • Subconjunctival bevacizumab for corneal neovascularization
    • Zaki AA, Farid SF. Subconjunctival bevacizumab for corneal neovascularization. Acta Ophthalmol 2010;88: 868-871.
    • (2010) Acta Ophthalmol , vol.88 , pp. 868-871
    • Zaki, A.A.1    Farid, S.F.2
  • 69
    • 35348978227 scopus 로고    scopus 로고
    • Subconjunctival bevacizumab for vascularized rejected corneal grafts
    • Awadein A. Subconjunctival bevacizumab for vascularized rejected corneal grafts. J Cataract Refract Surg 2007;33: 1991-1993.
    • (2007) J Cataract Refract Surg , vol.33 , pp. 1991-1993
    • Awadein, A.1
  • 70
    • 34548722080 scopus 로고    scopus 로고
    • Subconjunctival bevacizumab for corneal neovascularization
    • Erdurmus M, Totan Y. Subconjunctival bevacizumab for corneal neovascularization. Graefes Arch Clin Exp Ophthalmol 2007;245:1577-1579.
    • (2007) Graefes Arch Clin Exp Ophthalmol , vol.245 , pp. 1577-1579
    • Erdurmus, M.1    Totan, Y.2
  • 71
    • 20444431549 scopus 로고    scopus 로고
    • Topical FK506 as immunoprophylaxis after allogeneic penetrating normal-risk keratoplasty: A randomized clinical pilot study
    • Reinhard T, Mayweg S, Reis A, et al. Topical FK506 as immunoprophylaxis after allogeneic penetrating normal-risk keratoplasty: a randomized clinical pilot study. Transpl Int 2005;18:193-197.
    • (2005) Transpl Int , vol.18 , pp. 193-197
    • Reinhard, T.1    Mayweg, S.2    Reis, A.3
  • 72
    • 42549169600 scopus 로고    scopus 로고
    • Long-term use of topical tacrolimus (FK506) in high-risk penetrating keratoplasty
    • Dhaliwal JS, Mason BF, Kaufman SC. Long-term use of topical tacrolimus (FK506) in high-risk penetrating keratoplasty. Cornea 2008;27:488-493.
    • (2008) Cornea , vol.27 , pp. 488-493
    • Dhaliwal, J.S.1    Mason, B.F.2    Kaufman, S.C.3
  • 73
    • 0034808168 scopus 로고    scopus 로고
    • Tacrolimus (FK506) in the management of high-risk corneal and limbal grafts
    • Sloper CM, Powell RJ, Dua HS. Tacrolimus (FK506) in the management of high-risk corneal and limbal grafts. Ophthalmology 2001;108:1838-1844.
    • (2001) Ophthalmology , vol.108 , pp. 1838-1844
    • Sloper, C.M.1    Powell, R.J.2    Dua, H.S.3
  • 74
    • 33846233032 scopus 로고    scopus 로고
    • Tacrolimus immunosuppression in high-risk corneal grafts
    • Joseph A, Raj D, Shanmuganathan V, et al. Tacrolimus immunosuppression in high-risk corneal grafts. Br J Ophthalmol 2007;91:51-55.
    • (2007) Br J Ophthalmol , vol.91 , pp. 51-55
    • Joseph, A.1    Raj, D.2    Shanmuganathan, V.3
  • 75
    • 77955550035 scopus 로고    scopus 로고
    • Efficacy of topical cyclosporine A 2% in prevention of graft rejection in high-risk keratoplasty: A randomized controlled trial
    • Sinha R, Jhanji V, Verma K, et al. Efficacy of topical cyclosporine A 2% in prevention of graft rejection in high-risk keratoplasty: a randomized controlled trial. Graefes Arch Clin Exp Ophthalmol 2010;248:1167-1172.
    • (2010) Graefes Arch Clin Exp Ophthalmol , vol.248 , pp. 1167-1172
    • Sinha, R.1    Jhanji, V.2    Verma, K.3
  • 76
    • 0024371199 scopus 로고
    • Topical cyclospor-ine in high-risk corneal transplants
    • Belin MW, Bouchard CS, Frantz S, et al. Topical cyclospor-ine in high-risk corneal transplants. Ophthalmology 1989;96: 1144-1150.
    • (1989) Ophthalmology , vol.96 , pp. 1144-1150
    • Belin, M.W.1    Bouchard, C.S.2    Frantz, S.3
  • 77
    • 0037531367 scopus 로고    scopus 로고
    • Topical cyclosporine in pediatric keratoplasty
    • Cosar CB, Laibson PR, Cohen EJ, et al. Topical cyclosporine in pediatric keratoplasty. Eye Contact Lens 2003;29:103-107.
    • (2003) Eye Contact Lens , vol.29 , pp. 103-107
    • Cosar, C.B.1    Laibson, P.R.2    Cohen, E.J.3
  • 78
    • 0023845570 scopus 로고
    • Successful engraftment of high-risk corneal allografts with short-term immunosuppression with cyclosporine
    • Miller K, Huber C, Niederwieser D, et al. Successful engraftment of high-risk corneal allografts with short-term immunosuppression with cyclosporine. Transplantation 1988;45:651-653.
    • (1988) Transplantation , vol.45 , pp. 651-653
    • Miller, K.1    Huber, C.2    Niederwieser, D.3
  • 79
    • 50849139860 scopus 로고    scopus 로고
    • Topical Cyclosporin A in the treatment of acute graft rejection: A randomized controlled trial
    • Poon A, Constantinou M, Lamoureux E, et al. Topical Cyclosporin A in the treatment of acute graft rejection: a randomized controlled trial. Clin Experiment Ophthalmol 2008;36:415-421.
    • (2008) Clin Experiment Ophthalmol , vol.36 , pp. 415-421
    • Poon, A.1    Constantinou, M.2    Lamoureux, E.3
  • 80
    • 0030184564 scopus 로고    scopus 로고
    • Cyclosporin-A and its metabolites in the anterior
    • chamber after topical and systemic application as determined with high-performance liquid chromatography-electrospray mass spectrometry
    • Althaus C, Dagres E, Reinhard T, et al. Cyclosporin-A and its metabolites in the anterior chamber after topical and systemic application as determined with high-performance liquid chromatography-electrospray mass spectrometry. Ger J Ophthalmol 1996;5:189-194.
    • (1996) Ger J Ophthalmol , vol.5 , pp. 189-194
    • Althaus, C.1    Dagres, E.2    Reinhard, T.3
  • 81
    • 0032713210 scopus 로고    scopus 로고
    • Mycophenolate mofetil versus cyclosporin A in high risk keratoplasty patients: A prospectively randomised clinical trial
    • Reis A, Reinhard T, Voiculescu A, et al. Mycophenolate mofetil versus cyclosporin A in high risk keratoplasty patients: a prospectively randomised clinical trial. Br J Ophthalmol 1999;83:1268-1271.
    • (1999) Br J Ophthalmol , vol.83 , pp. 1268-1271
    • Reis, A.1    Reinhard, T.2    Voiculescu, A.3
  • 82
    • 23244452959 scopus 로고    scopus 로고
    • Systemic mycophenolate mofetil avoids immune reactions in penetrating high-risk keratoplasty: Preliminary results of an ongoing prospectively randomized multicentre study
    • Reinhard T, Mayweg S, Sokolovska Y, et al. Systemic mycophenolate mofetil avoids immune reactions in penetrating high-risk keratoplasty: preliminary results of an ongoing prospectively randomized multicentre study. Transpl Int 2005;18:703-708.
    • (2005) Transpl Int , vol.18 , pp. 703-708
    • Reinhard, T.1    Mayweg, S.2    Sokolovska, Y.3
  • 83
    • 33645090964 scopus 로고    scopus 로고
    • An open prospective pilot study on the use of rapamycin after penetrating high-risk keratoplasty
    • Birnbaum F, Reis A, Bohringer D, et al. An open prospective pilot study on the use of rapamycin after penetrating high-risk keratoplasty. Transplantation 2006;81:767-772.
    • (2006) Transplantation , vol.81 , pp. 767-772
    • Birnbaum, F.1    Reis, A.2    Bohringer, D.3
  • 84
    • 77952827770 scopus 로고    scopus 로고
    • Sirolimus and mycophenolate as combination prophylaxis in corneal transplant recipients at high rejection risk
    • Chatel MA, Larkin DF. Sirolimus and mycophenolate as combination prophylaxis in corneal transplant recipients at high rejection risk. Am J Ophthalmol 2010;150:179-184.
    • (2010) Am J Ophthalmol , vol.150 , pp. 179-184
    • Chatel, M.A.1    Larkin, D.F.2
  • 85
    • 0024571784 scopus 로고
    • Usefulness of CD3 or CD6 anti-T monoclonal antibodies in the treatment of acute corneal graft rejection
    • Ippoliti G, Fronterre A. Usefulness of CD3 or CD6 anti-T monoclonal antibodies in the treatment of acute corneal graft rejection. Transplant Proc 1989;21:3133-3134.
    • (1989) Transplant Proc , vol.21 , pp. 3133-3134
    • Ippoliti, G.1    Fronterre, A.2
  • 86
    • 0023281496 scopus 로고
    • Use of locally injected anti-T monoclonal antibodies in the treatment of acute corneal graft rejection
    • Ippoliti G, Fronterre A. Use of locally injected anti-T monoclonal antibodies in the treatment of acute corneal graft rejection. Transplant Proc 1987;19:2579-2580.
    • (1987) Transplant Proc , vol.19 , pp. 2579-2580
    • Ippoliti, G.1    Fronterre, A.2
  • 87
    • 0036461383 scopus 로고    scopus 로고
    • Immunsuppression durch Kombinationstherapie mit Basiliximab und Ciclosporin bei Hochrisikokeratoplastik. Eine Pilotstudie [Immune suppression by combination therapy with basiliximab and cyclosporin in high risk keratoplasty. A pilot study]
    • Schmitz K, Hitzer S, Behrens-Baumann W. Immunsuppression durch Kombinationstherapie mit Basiliximab und Ciclosporin bei Hochrisikokeratoplastik. Eine Pilotstudie [Immune suppression by combination therapy with basiliximab and cyclosporin in high risk keratoplasty. A pilot study]. Ophthalmologe 2002;99:38-45.
    • (2002) Ophthalmologe , vol.99 , pp. 38-45
    • Schmitz, K.1    Hitzer, S.2    Behrens-Baumann, W.3
  • 88
    • 39149125787 scopus 로고    scopus 로고
    • Basiliximab als Monotherapie nach perforierender Risikokeratoplastik: eine prospektive randomisierte Pilotstudie [Basiliximab following penetrating risk-keratoplasty: a prospective randomized pilot study]
    • Birnbaum F, Jehle T, Schwartzkopff J, et al. Basiliximab als Monotherapie nach perforierender Risikokeratoplastik: eine prospektive randomisierte Pilotstudie [Basiliximab following penetrating risk-keratoplasty: a prospective randomized pilot study]. Klin Monbl Augenheilkd 2008;225: 62-65.
    • (2008) Klin Monbl Augenheilkd , vol.225 , pp. 62-65
    • Birnbaum, F.1    Jehle, T.2    Schwartzkopff, J.3
  • 89
    • 0033823767 scopus 로고    scopus 로고
    • Immune privilege and immunogenicity reside among different layers of the mouse cornea
    • Hori J, Joyce NC, Streilein JW. Immune privilege and immunogenicity reside among different layers of the mouse cornea. Invest Ophthalmol Vis Sci 2000;41: 3032-3042.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 3032-3042
    • Hori, J.1    Joyce, N.C.2    Streilein, J.W.3
  • 90
    • 33947509344 scopus 로고    scopus 로고
    • Immune privilege and angiogenic privilege of the cornea
    • Cursiefen C. Immune privilege and angiogenic privilege of the cornea. Chem Immunol Allergy 2007;92:50-57.
    • (2007) Chem Immunol Allergy , vol.92 , pp. 50-57
    • Cursiefen, C.1
  • 91
    • 63649163872 scopus 로고    scopus 로고
    • Genetic manipulation of corneal endothelial cells: Transfection and viral transduction
    • Bertelmann E. Genetic manipulation of corneal endothelial cells: transfection and viral transduction. Methods Mol Biol 2009;467:229-239.
    • (2009) Methods Mol Biol , vol.467 , pp. 229-239
    • Bertelmann, E.1
  • 92
    • 84856545175 scopus 로고    scopus 로고
    • A new tool for the transfection of corneal endothelial cells: Calcium phosphate nanoparticles
    • Hu J, Kovtun A, Tomaszewski A, et al. A new tool for the transfection of corneal endothelial cells: calcium phosphate nanoparticles. Acta Biomater 2012;8:1156-1163.
    • (2012) Acta Biomater , vol.8 , pp. 1156-1163
    • Hu, J.1    Kovtun, A.2    Tomaszewski, A.3
  • 93
    • 84861127428 scopus 로고    scopus 로고
    • Nanoparticle-mediated delivery of shRNA.VEGF-A plasmids regresses corneal neovascularization
    • Qazi Y, Stagg B, Singh N, et al. Nanoparticle-mediated delivery of shRNA.VEGF-a plasmids regresses corneal neovascularization. Invest Ophthalmol Vis Sci 2012;53: 2837-2844.
    • (2012) Invest Ophthalmol Vis Sci , vol.53 , pp. 2837-2844
    • Qazi, Y.1    Stagg, B.2    Singh, N.3
  • 94
    • 1242276573 scopus 로고    scopus 로고
    • Designing gene delivery vectors for cardiovascular gene therapy
    • Baker AH. Designing gene delivery vectors for cardiovascular gene therapy. Prog Biophys Mol Biol 2004;84: 279-299.
    • (2004) Prog Biophys Mol Biol , vol.84 , pp. 279-299
    • Baker, A.H.1
  • 95
    • 0142090629 scopus 로고    scopus 로고
    • Adeno-associated viral vectors for retinal gene transfer
    • Surace EM, Auricchio A. Adeno-associated viral vectors for retinal gene transfer. Prog Retin Eye Res 2003;22:705-719.
    • (2003) Prog Retin Eye Res , vol.22 , pp. 705-719
    • Surace, E.M.1    Auricchio, A.2
  • 96
    • 0000557447 scopus 로고    scopus 로고
    • Adenoviridae: The viruses and their teplication
    • Fields B, Knipe, DM, Howley, PM, eds. Philadelphia: Lippincott-Raven
    • Shenk T. Adenoviridae: The viruses and their teplication. In: Fields Virology, 3rd ed. Fields B, Knipe, DM, Howley, PM, eds. Philadelphia: Lippincott-Raven, 1996. pp 2111-2148.
    • (1996) Fields Virology, 3rd Ed , pp. 2111-2148
    • Shenk, T.1
  • 98
    • 0031052263 scopus 로고    scopus 로고
    • Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5
    • Bergelson JM, Cunningham JA, Droguett G, et al. Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5. Science 1997;275:1320-1323.
    • (1997) Science , vol.275 , pp. 1320-1323
    • Bergelson, J.M.1    Cunningham, J.A.2    Droguett, G.3
  • 99
    • 0030915715 scopus 로고    scopus 로고
    • HCAR and MCAR: The human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses
    • Tomko RP, Xu R, Philipson L. HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses. Proc Natl Acad Sci USA 1997;94:3352-3356.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 3352-3356
    • Tomko, R.P.1    Xu, R.2    Philipson, L.3
  • 100
    • 0027166647 scopus 로고
    • Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment
    • Wickham TJ, Mathias P, Cheresh DA, et al. Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment. Cell 1993;73: 309-319.
    • (1993) Cell , vol.73 , pp. 309-319
    • Wickham, T.J.1    Mathias, P.2    Cheresh, D.A.3
  • 101
    • 3142579755 scopus 로고    scopus 로고
    • Ex vivo adeno-virus-mediated gene transfer to corneal graft endothelial cells in mice
    • Qian Y, Leong FL, Kazlauskas A, et al. Ex vivo adeno-virus-mediated gene transfer to corneal graft endothelial cells in mice. Invest Ophthalmol Vis Sci 2004;45:2187-2193.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 2187-2193
    • Qian, Y.1    Leong, F.L.2    Kazlauskas, A.3
  • 102
    • 0028953829 scopus 로고
    • An SV40-immortalized human corneal epithelial cell line and its characterization
    • Araki-Sasaki K, Ohashi Y, Sasabe T, et al. An SV40-immortalized human corneal epithelial cell line and its characterization. Invest Ophthalmol Vis Sci 1995;36: 614-621.
    • (1995) Invest Ophthalmol Vis Sci , vol.36 , pp. 614-621
    • Araki-Sasaki, K.1    Ohashi, Y.2    Sasabe, T.3
  • 103
    • 0028387355 scopus 로고
    • In vivo adenovirus-mediated gene transfer into ocular tissues
    • Mashhour B, Couton D, Perricaudet M, et al. In vivo adenovirus-mediated gene transfer into ocular tissues. Gene Ther 1994;1:122-126.
    • (1994) Gene Ther , vol.1 , pp. 122-126
    • Mashhour, B.1    Couton, D.2    Perricaudet, M.3
  • 104
    • 0028889647 scopus 로고
    • In vivo gene transfer into murine corneal endothelial and trabecular meshwork cells
    • Budenz DL, Bennett J, Alonso L, et al. In vivo gene transfer into murine corneal endothelial and trabecular meshwork cells. Invest Ophthalmol Vis Sci 1995;36: 2211-2215.
    • (1995) Invest Ophthalmol Vis Sci , vol.36 , pp. 2211-2215
    • Budenz, D.L.1    Bennett, J.2    Alonso, L.3
  • 105
    • 0030025064 scopus 로고    scopus 로고
    • Adenovirus-mediated gene delivery to the corneal endothelium
    • Larkin DF, Oral HB, Ring CJ, et al. Adenovirus-mediated gene delivery to the corneal endothelium. Transplantation 1996;61:363-370.
    • (1996) Transplantation , vol.61 , pp. 363-370
    • Larkin, D.F.1    Oral, H.B.2    Ring, C.J.3
  • 106
    • 0032413204 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer to the ocular surface epithelium
    • Tsubota K, Inoue H, Ando K, et al. Adenovirus-mediated gene transfer to the ocular surface epithelium. Exp Eye Res 1998;67:531-538.
    • (1998) Exp Eye Res , vol.67 , pp. 531-538
    • Tsubota, K.1    Inoue, H.2    Ando, K.3
  • 107
    • 0035872802 scopus 로고    scopus 로고
    • Prolongation of sheep corneal allograft survival by ex vivo transfer of the gene encoding interleukin-10
    • Klebe S, Sykes PJ, Coster DJ, et al. Prolongation of sheep corneal allograft survival by ex vivo transfer of the gene encoding interleukin-10. Transplantation 2001;71: 1214-1220.
    • (2001) Transplantation , vol.71 , pp. 1214-1220
    • Klebe, S.1    Sykes, P.J.2    Coster, D.J.3
  • 108
    • 0029887454 scopus 로고    scopus 로고
    • Ocular adenovirus gene transfer varies in efficiency and inflammatory response
    • Borras T, Tamm ER, Zigler Jr JS. Ocular adenovirus gene transfer varies in efficiency and inflammatory response. Invest Ophthalmol Vis Sci 1996;37:1282-1293.
    • (1996) Invest Ophthalmol Vis Sci , vol.37 , pp. 1282-1293
    • Borras, T.1    Tamm, E.R.2    Zigler Jr., J.S.3
  • 109
    • 0035459495 scopus 로고    scopus 로고
    • Non-invasive observation of repeated adenoviral GFP gene delivery to the anterior segment of the monkey eye in vivo
    • Borras T, Gabelt BT, Klintworth GK, et al. Non-invasive observation of repeated adenoviral GFP gene delivery to the anterior segment of the monkey eye in vivo. J Gene Med 2001;3:437-449.
    • (2001) J Gene Med , vol.3 , pp. 437-449
    • Borras, T.1    Gabelt, B.T.2    Klintworth, G.K.3
  • 110
    • 0030840092 scopus 로고    scopus 로고
    • Ex vivo adeno-virus-mediated gene transfer and immunomodulatory protein production in human cornea
    • Oral HB, Larkin DF, Fehervari Z, et al. Ex vivo adeno-virus-mediated gene transfer and immunomodulatory protein production in human cornea. Gene Ther 1997;4: 639-647.
    • (1997) Gene Ther , vol.4 , pp. 639-647
    • Oral, H.B.1    Larkin, D.F.2    Fehervari, Z.3
  • 111
    • 0001142644 scopus 로고    scopus 로고
    • Parvoviridae: The viruses and their replication
    • Knipe D, Howley PM, eds. Philadelphia: Lippincott Williams and Wilkins
    • Muzyczka N, and Berns KI. Parvoviridae: The viruses and their replication. In: Fields Virology, 4th ed. Knipe D, Howley PM, eds. Philadelphia: Lippincott Williams and Wilkins, 2001. pp 2327-2360.
    • (2001) Fields Virology, 4th Ed , pp. 2327-2360
    • Muzyczka, N.1    Berns, K.I.2
  • 112
    • 2342431902 scopus 로고    scopus 로고
    • Recombinant adeno-associated virus as delivery vector for gene therapy: A review
    • Lu Y. Recombinant adeno-associated virus as delivery vector for gene therapy: a review. Stem Cells Dev 2004;13: 133-145.
    • (2004) Stem Cells Dev , vol.13 , pp. 133-145
    • Lu, Y.1
  • 113
    • 0038150506 scopus 로고    scopus 로고
    • Helper virus-free, optically controllable, and two-plasmid-based production of adeno-associated virus vectors of serotypes 1 to 6
    • Grimm D, Kay MA, Kleinschmidt JA. Helper virus-free, optically controllable, and two-plasmid-based production of adeno-associated virus vectors of serotypes 1 to 6. Mol Ther 2003;7:839-850.
    • (2003) Mol Ther , vol.7 , pp. 839-850
    • Grimm, D.1    Kay, M.A.2    Kleinschmidt, J.A.3
  • 114
    • 0031984786 scopus 로고    scopus 로고
    • Infectious clones and vectors derived from adeno-associated virus (AAV) serotypes other than AAV type 2
    • Rutledge EA, Halbert CL, Russell DW. Infectious clones and vectors derived from adeno-associated virus (AAV) serotypes other than AAV type 2. J Virol 1998;72:309-319.
    • (1998) J Virol , vol.72 , pp. 309-319
    • Rutledge, E.A.1    Halbert, C.L.2    Russell, D.W.3
  • 115
    • 0031906147 scopus 로고    scopus 로고
    • Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions
    • Summerford C, Samulski RJ. Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions. J Virol 1998;72:1438-1445.
    • (1998) J Virol , vol.72 , pp. 1438-1445
    • Summerford, C.1    Samulski, R.J.2
  • 116
    • 0035827546 scopus 로고    scopus 로고
    • Binding of adeno-associated virus type 5 to 2, 3-linked sialic acid is required for gene transfer
    • Walters RW, Yi SM, Keshavjee S, et al. Binding of adeno-associated virus type 5 to 2, 3-linked sialic acid is required for gene transfer. J Biol Chem 2001;276:20610-20616.
    • (2001) J Biol Chem , vol.276 , pp. 20610-20616
    • Walters, R.W.1    Yi, S.M.2    Keshavjee, S.3
  • 117
    • 0036140216 scopus 로고    scopus 로고
    • Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduc-tion with broad specificity
    • Rabinowitz JE, Rolling F, Li C, et al. Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduc-tion with broad specificity. J Virol 2002;76:791-801.
    • (2002) J Virol , vol.76 , pp. 791-801
    • Rabinowitz, J.E.1    Rolling, F.2    Li, C.3
  • 119
    • 0037373780 scopus 로고    scopus 로고
    • Gene transfer into rabbit keratocytes using AAV and lipid-mediated plasmid DNA vectors with a lamellar flap for stromal access
    • Mohan RR, Schultz GS, Hong JW, et al. Gene transfer into rabbit keratocytes using AAV and lipid-mediated plasmid DNA vectors with a lamellar flap for stromal access. Exp Eye Res 2003;76:373-383.
    • (2003) Exp Eye Res , vol.76 , pp. 373-383
    • Mohan, R.R.1    Schultz, G.S.2    Hong, J.W.3
  • 120
    • 0034069618 scopus 로고    scopus 로고
    • Adeno-associated and herpes simplex viruses as vectors for gene transfer to the corneal endothelium
    • Hudde T, Rayner SA, De Alwis M, et al. Adeno-associated and herpes simplex viruses as vectors for gene transfer to the corneal endothelium. Cornea 2000;19:369-373.
    • (2000) Cornea , vol.19 , pp. 369-373
    • Hudde, T.1    Rayner, S.A.2    De Alwis, M.3
  • 121
    • 0036187464 scopus 로고    scopus 로고
    • Inducible adeno-associated virus vector-delivered transgene expression in corneal endothelium
    • Tsai ML, Chen SL, Chou PI, et al. Inducible adeno-associated virus vector-delivered transgene expression in corneal endothelium. Invest Ophthalmol Vis Sci 2002;43: 751-757.
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , pp. 751-757
    • Tsai, M.L.1    Chen, S.L.2    Chou, P.I.3
  • 122
    • 0037015049 scopus 로고    scopus 로고
    • Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy
    • Gao GP, Alvira MR, Wang L, et al. Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy. Proc Natl Acad Sci USA 2002;99: 11854-11859.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 11854-11859
    • Gao, G.P.1    Alvira, M.R.2    Wang, L.3
  • 123
    • 73149120964 scopus 로고    scopus 로고
    • Transduction efficiency of AAV 2/6, 2/8 and 2/9 vectors for delivering genes in human corneal fibroblasts
    • Sharma A, Ghosh A, Hansen ET, et al. Transduction efficiency of AAV 2/6, 2/8 and 2/9 vectors for delivering genes in human corneal fibroblasts. Brain Res Bull 2010;81: 273-278.
    • (2010) Brain Res Bull , vol.81 , pp. 273-278
    • Sharma, A.1    Ghosh, A.2    Hansen, E.T.3
  • 124
    • 0034121397 scopus 로고    scopus 로고
    • A new dual-vector approach to enhance recombinant adeno-associated virus-mediated gene expression through intermolecular cis activation
    • Duan D, Yue Y, Yan Z, et al. A new dual-vector approach to enhance recombinant adeno-associated virus-mediated gene expression through intermolecular cis activation. Nat Med 2000;6:595-598.
    • (2000) Nat Med , vol.6 , pp. 595-598
    • Duan, D.1    Yue, Y.2    Yan, Z.3
  • 125
    • 0034121579 scopus 로고    scopus 로고
    • Overcoming adeno-associated virus vector size limitation through viral DNA hetero-dimerization
    • Sun L, Li J, Xiao X. Overcoming adeno-associated virus vector size limitation through viral DNA hetero-dimerization. Nat Med 2000;6:599-602.
    • (2000) Nat Med , vol.6 , pp. 599-602
    • Sun, L.1    Li, J.2    Xiao, X.3
  • 126
    • 79551634862 scopus 로고    scopus 로고
    • Novel properties of tyrosine-mutant AAV2 vectors in the mouse retina
    • Petrs-Silva H, Dinculescu A, Li Q, et al. Novel properties of tyrosine-mutant AAV2 vectors in the mouse retina. Mol Ther 2011;19:293-301.
    • (2011) Mol Ther , vol.19 , pp. 293-301
    • Petrs-Silva, H.1    Dinculescu, A.2    Li, Q.3
  • 127
    • 61649095399 scopus 로고    scopus 로고
    • High-efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectors
    • Petrs-Silva H, Dinculescu A, Li Q, et al. High-efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectors. Mol Ther 2009;17:463-471.
    • (2009) Mol Ther , vol.17 , pp. 463-471
    • Petrs-Silva, H.1    Dinculescu, A.2    Li, Q.3
  • 128
    • 54549096772 scopus 로고    scopus 로고
    • Tyrosine-phosphor-ylation of AAV2 vectors and its consequences on viral intracellular trafficking and transgene expression
    • Zhong L, Li B, Jayandharan G, et al. Tyrosine-phosphor-ylation of AAV2 vectors and its consequences on viral intracellular trafficking and transgene expression. Virology 2008;381:194-202.
    • (2008) Virology , vol.381 , pp. 194-202
    • Zhong, L.1    Li, B.2    Jayandharan, G.3
  • 129
    • 45549090635 scopus 로고    scopus 로고
    • Next generation of adeno-associated virus 2 vectors: Point mutations in tyrosines lead to high-efficiency transduction at lower doses
    • Zhong L, Li B, Mah CS, et al. Next generation of adeno-associated virus 2 vectors: point mutations in tyrosines lead to high-efficiency transduction at lower doses. Proc Natl Acad Sci USA 2008;105:7827-7832.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 7827-7832
    • Zhong, L.1    Li, B.2    Mah, C.S.3
  • 131
    • 13344261388 scopus 로고    scopus 로고
    • Molecular biology and pathogen-esis of animal lentivirus infections
    • Clements JE, Zink MC. Molecular biology and pathogen-esis of animal lentivirus infections. Clin Microbiol Rev 1996;9:100-117.
    • (1996) Clin Microbiol Rev , vol.9 , pp. 100-117
    • Clements, J.E.1    Zink, M.C.2
  • 132
    • 0025072487 scopus 로고
    • Functions of the auxiliary gene products of the human immunodeficiency virus type 1
    • Cullen BR, Greene WC. Functions of the auxiliary gene products of the human immunodeficiency virus type 1. Virology 1990;178:1-5.
    • (1990) Virology , vol.178 , pp. 1-5
    • Cullen, B.R.1    Greene, W.C.2
  • 133
    • 0023759168 scopus 로고
    • HIV infection does not require endocytosis of its receptor, CD4
    • Maddon PJ, McDougal JS, Clapham PR, et al. HIV infection does not require endocytosis of its receptor, CD4. Cell 1988;54:865-874.
    • (1988) Cell , vol.54 , pp. 865-874
    • Maddon, P.J.1    McDougal, J.S.2    Clapham, P.R.3
  • 134
    • 0023028190 scopus 로고
    • The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain
    • Maddon PJ, Dalgleish AG, McDougal JS, et al. The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain. Cell 1986;47:333-348.
    • (1986) Cell , vol.47 , pp. 333-348
    • Maddon, P.J.1    Dalgleish, A.G.2    McDougal, J.S.3
  • 136
    • 0033994663 scopus 로고    scopus 로고
    • Efficient and sustained transgene expression in human corneal cells mediated by a lentiviral vector
    • Wang X, Appukuttan B, Ott S, et al. Efficient and sustained transgene expression in human corneal cells mediated by a lentiviral vector. Gene Ther 2000;7:196-200.
    • (2000) Gene Ther , vol.7 , pp. 196-200
    • Wang, X.1    Appukuttan, B.2    Ott, S.3
  • 137
    • 0035182556 scopus 로고    scopus 로고
    • In vivo gene transfer to the mouse eye using an HIV-based lentiviral vector; Efficient long-term transduction of corneal endo-thelium and retinal pigment epithelium
    • Bainbridge JW, Stephens C, Parsley K, et al. In vivo gene transfer to the mouse eye using an HIV-based lentiviral vector; efficient long-term transduction of corneal endo-thelium and retinal pigment epithelium. Gene Ther 2001;8: 1665-1668.
    • (2001) Gene Ther , vol.8 , pp. 1665-1668
    • Bainbridge, J.W.1    Stephens, C.2    Parsley, K.3
  • 138
    • 0036376655 scopus 로고    scopus 로고
    • Sustained transduc-tion of ocular cells with a bovine immunodeficiency viral vector
    • Takahashi K, Luo T, Saishin Y, et al. Sustained transduc-tion of ocular cells with a bovine immunodeficiency viral vector. Hum Gene Ther 2002;13:1305-1316.
    • (2002) Hum Gene Ther , vol.13 , pp. 1305-1316
    • Takahashi, K.1    Luo, T.2    Saishin, Y.3
  • 139
    • 79955449949 scopus 로고    scopus 로고
    • Corneal endothelial cells are protected from apoptosis by gene therapy
    • Fuchsluger TA, Jurkunas U, Kazlauskas A, et al. Corneal endothelial cells are protected from apoptosis by gene therapy. Hum Gene Ther 2011;22:549-558.
    • (2011) Hum Gene Ther , vol.22 , pp. 549-558
    • Fuchsluger, T.A.1    Jurkunas, U.2    Kazlauskas, A.3
  • 140
    • 80051802103 scopus 로고    scopus 로고
    • Anti-apoptotic gene therapy prolongs survival of corneal endothelial cells during storage
    • Fuchsluger TA, Jurkunas U, Kazlauskas A, et al. Anti-apoptotic gene therapy prolongs survival of corneal endothelial cells during storage. Gene Ther 2011;18: 778-787.
    • (2011) Gene Ther , vol.18 , pp. 778-787
    • Fuchsluger, T.A.1    Jurkunas, U.2    Kazlauskas, A.3
  • 141
    • 77954641049 scopus 로고    scopus 로고
    • Lentivirus-mediated gene transfer of interleukin 10 to the ovine and human cornea
    • Parker DG, Coster DJ, Brereton HM, et al. Lentivirus-mediated gene transfer of interleukin 10 to the ovine and human cornea. Clin Experiment Ophthalmol 2010;38: 405-413.
    • (2010) Clin Experiment Ophthalmol , vol.38 , pp. 405-413
    • Parker, D.G.1    Coster, D.J.2    Brereton, H.M.3
  • 142
    • 77951768401 scopus 로고    scopus 로고
    • Ocular tolerance to a topical formulation of hyaluronic acid and chitosan-based nanoparticles
    • Contreras-Ruiz L, de la Fuente M, Garcia-Vazquez C, et al. Ocular tolerance to a topical formulation of hyaluronic acid and chitosan-based nanoparticles. Cornea 2010;29: 550-558.
    • (2010) Cornea , vol.29 , pp. 550-558
    • Contreras-Ruiz, L.1    De La Fuente, M.2    Garcia-Vazquez, C.3
  • 143
    • 78649739026 scopus 로고    scopus 로고
    • In vivo evaluation of novel nanoparticles containing dexametha-sone for ocular drug delivery on rabbit eye
    • Rafie F, Javadzadeh Y, Javadzadeh AR, et al. In vivo evaluation of novel nanoparticles containing dexametha-sone for ocular drug delivery on rabbit eye. Curr Eye Res 2010;35:1081-1089.
    • (2010) Curr Eye Res , vol.35 , pp. 1081-1089
    • Rafie, F.1    Javadzadeh, Y.2    Javadzadeh, A.R.3
  • 144
    • 34248570405 scopus 로고    scopus 로고
    • Efficient non-viral ocular gene transfer with compacted DNA nanoparticles
    • Farjo R, Skaggs J, Quiambao AB, et al. Efficient non-viral ocular gene transfer with compacted DNA nanoparticles. PLoS One 2006;1:e38.
    • (2006) PLoS One , vol.1
    • Farjo, R.1    Skaggs, J.2    Quiambao, A.B.3
  • 145
    • 0042844771 scopus 로고    scopus 로고
    • Ocular drug delivery targeting the retina and retinal pigment epithelium using polylactide nanoparticles
    • Bourges JL, Gautier SE, Delie F, et al. Ocular drug delivery targeting the retina and retinal pigment epithelium using polylactide nanoparticles. Invest Ophthalmol Vis Sci 2003; 44:3562-3569.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 3562-3569
    • Bourges, J.L.1    Gautier, S.E.2    Delie, F.3
  • 146
    • 77951632478 scopus 로고    scopus 로고
    • Gene delivery to mitotic and postmitotic photoreceptors via compacted DNA nanoparticles results in improved phenotype in a mouse model of retinitis pigmentosa
    • Cai X, Conley SM, Nash Z, et al. Gene delivery to mitotic and postmitotic photoreceptors via compacted DNA nanoparticles results in improved phenotype in a mouse model of retinitis pigmentosa. Faseb J 2010;24:1178-1191.
    • (2010) Faseb J , vol.24 , pp. 1178-1191
    • Cai, X.1    Conley, S.M.2    Nash, Z.3
  • 147
    • 70350733741 scopus 로고    scopus 로고
    • Ocular delivery of compacted DNA-nanoparticles does not elicit toxicity in the mouse retina
    • Ding XQ, Quiambao AB, Fitzgerald JB, et al. Ocular delivery of compacted DNA-nanoparticles does not elicit toxicity in the mouse retina. PLoS One 2009;4:e7410.
    • (2009) PLoS One , vol.4
    • Ding, X.Q.1    Quiambao, A.B.2    Fitzgerald, J.B.3
  • 148
    • 0347917175 scopus 로고    scopus 로고
    • Minimal toxicity of stabilized compacted DNA nanoparticles in the murine lung
    • Ziady AG, Gedeon CR, Muhammad O, et al. Minimal toxicity of stabilized compacted DNA nanoparticles in the murine lung. Mol Ther 2003;8:948-956.
    • (2003) Mol Ther , vol.8 , pp. 948-956
    • Ziady, A.G.1    Gedeon, C.R.2    Muhammad, O.3
  • 149
    • 84874502028 scopus 로고    scopus 로고
    • Development of solid lipid nanoparticles and nanostructured lipid carriers for improving ocular delivery of acyclovir
    • Seyfoddin A, Al-Kassas R. Development of solid lipid nanoparticles and nanostructured lipid carriers for improving ocular delivery of acyclovir. Drug Dev Ind Pharm 2013;39:508-519.
    • (2013) Drug Dev Ind Pharm , vol.39 , pp. 508-519
    • Seyfoddin, A.1    Al-Kassas, R.2
  • 150
    • 84856022970 scopus 로고    scopus 로고
    • Polymeric cyclosporine-A nanoparticles for ocular application
    • Basaran E, Demirel M, Sirmagul B, et al. Polymeric cyclosporine-A nanoparticles for ocular application. J Biomed Nanotechnol 2011;7:714-723.
    • (2011) J Biomed Nanotechnol , vol.7 , pp. 714-723
    • Basaran, E.1    Demirel, M.2    Sirmagul, B.3
  • 151
    • 84871276292 scopus 로고    scopus 로고
    • Comparative analysis of DNA nanoparticles and AAVs for ocular gene delivery
    • Han Z, Conley SM, Makkia R, et al. Comparative analysis of DNA nanoparticles and AAVs for ocular gene delivery. PLoS One 2012;7:e52189.
    • (2012) PLoS One , vol.7
    • Han, Z.1    Conley, S.M.2    Makkia, R.3
  • 152
    • 19944398726 scopus 로고    scopus 로고
    • Compacted DNA nanoparticles administered to the nasal mucosa of cystic fibrosis subjects are safe and demonstrate partial to complete cystic fibrosis transmembrane regulator reconstitution
    • Konstan MW, Davis PB, Wagener JS, et al. Compacted DNA nanoparticles administered to the nasal mucosa of cystic fibrosis subjects are safe and demonstrate partial to complete cystic fibrosis transmembrane regulator reconstitution. Hum Gene Ther 2004;15:1255-1269.
    • (2004) Hum Gene Ther , vol.15 , pp. 1255-1269
    • Konstan, M.W.1    Davis, P.B.2    Wagener, J.S.3
  • 154
    • 84855878356 scopus 로고    scopus 로고
    • Development of surface-functionalised nanoparticles for FGF2 receptor-based solid tumour targeting
    • Jain A, Gulbake A, Shilpi S, et al. Development of surface-functionalised nanoparticles for FGF2 receptor-based solid tumour targeting. J Microencapsul 2012;29:95-102.
    • (2012) J Microencapsul , vol.29 , pp. 95-102
    • Jain, A.1    Gulbake, A.2    Shilpi, S.3
  • 155
    • 61849100392 scopus 로고    scopus 로고
    • Click chemistry functionalized polymeric nanoparticles target corneal epithelial cells through RGD-cell surface receptors
    • Lu J, Shi M, Shoichet MS. Click chemistry functionalized polymeric nanoparticles target corneal epithelial cells through RGD-cell surface receptors. Bioconjug Chem 2009; 20:87-94.
    • (2009) Bioconjug Chem , vol.20 , pp. 87-94
    • Lu, J.1    Shi, M.2    Shoichet, M.S.3
  • 156
    • 0030013694 scopus 로고    scopus 로고
    • Efficient transfer of genetic material into mammalian cells using Starburst polyamidoamine dendrimers
    • Kukowska-Latallo JF, Bielinska AU, Johnson J, et al. Efficient transfer of genetic material into mammalian cells using Starburst polyamidoamine dendrimers. Proc Natl Acad Sci USA 1996;93:4897-4902.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 4897-4902
    • Kukowska-Latallo, J.F.1    Bielinska, A.U.2    Johnson, J.3
  • 157
    • 0030042315 scopus 로고    scopus 로고
    • Preliminary biological evaluation of polyamidoamine (PAMAM) starburst den-drimers
    • Roberts JC, Bhalgat MK, Zera RT. Preliminary biological evaluation of polyamidoamine (PAMAM) starburst den-drimers. J Biomed Mater Res 1996;30:53-65.
    • (1996) J Biomed Mater Res , vol.30 , pp. 53-65
    • Roberts, J.C.1    Bhalgat, M.K.2    Zera, R.T.3
  • 158
    • 0033016739 scopus 로고    scopus 로고
    • Activated polyamidoamine dendrimers, a non-viral vector for gene transfer to the corneal endothelium
    • Hudde T, Rayner SA, Comer RM, et al. Activated polyamidoamine dendrimers, a non-viral vector for gene transfer to the corneal endothelium. Gene Ther 1999;6:939-943.
    • (1999) Gene Ther , vol.6 , pp. 939-943
    • Hudde, T.1    Rayner, S.A.2    Comer, R.M.3
  • 159
    • 78149491409 scopus 로고    scopus 로고
    • Blocking neuropilin-2 enhances corneal allograft survival by selectively inhibiting lymphangiogenesis on vascularized beds
    • Tang XL, Sun JF, Wang XY, et al. Blocking neuropilin-2 enhances corneal allograft survival by selectively inhibiting lymphangiogenesis on vascularized beds. Mol Vis 2010;16:2354-2361.
    • (2010) Mol Vis , vol.16 , pp. 2354-2361
    • Tang, X.L.1    Sun, J.F.2    Wang, X.Y.3
  • 160
    • 84861157207 scopus 로고    scopus 로고
    • Flt23k nanoparticles offer additive benefit in graft survival and anti-angiogenic effects when combined with triamcinolone
    • Cho YK, Uehara H, Young JR, et al. Flt23k nanoparticles offer additive benefit in graft survival and anti-angiogenic effects when combined with triamcinolone. Invest Ophthalmol Vis Sci 2012;53:2328-2336.
    • (2012) Invest Ophthalmol Vis Sci , vol.53 , pp. 2328-2336
    • Cho, Y.K.1    Uehara, H.2    Young, J.R.3
  • 161
    • 84873357686 scopus 로고    scopus 로고
    • Vascular Endothelial Growth Factor Receptor 1 morpholino increases graft survival in a murine penetrating keratoplasty model
    • Cho YK, Zhang X, Uehara H, et al. Vascular Endothelial Growth Factor Receptor 1 morpholino increases graft survival in a murine penetrating keratoplasty model. Invest Ophthalmol Vis Sci 2012;53:8458-8471.
    • (2012) Invest Ophthalmol Vis Sci , vol.53 , pp. 8458-8471
    • Cho, Y.K.1    Zhang, X.2    Uehara, H.3
  • 162
    • 0346957021 scopus 로고    scopus 로고
    • Prospects for gene therapy in corneal disease
    • Jun AS, Larkin DF. Prospects for gene therapy in corneal disease. Eye (Lond) 2003;17:906-911.
    • (2003) Eye (Lond) , vol.17 , pp. 906-911
    • Jun, A.S.1    Larkin, D.F.2
  • 163
    • 0036202821 scopus 로고    scopus 로고
    • Effect of administration of CTLA4-Ig as protein or cDNA on corneal allograft survival
    • Comer RM, King WJ, Ardjomand N, et al. Effect of administration of CTLA4-Ig as protein or cDNA on corneal allograft survival. Invest Ophthalmol Vis Sci 2002; 43:1095-1103.
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , pp. 1095-1103
    • Comer, R.M.1    King, W.J.2    Ardjomand, N.3
  • 164
    • 33646239375 scopus 로고    scopus 로고
    • Influence of local and systemic CTLA4Ig gene transfer on corneal allograft survival
    • Gong N, Pleyer U, Yang J, et al. Influence of local and systemic CTLA4Ig gene transfer on corneal allograft survival. J Gene Med 2006;8:459-467.
    • (2006) J Gene Med , vol.8 , pp. 459-467
    • Gong, N.1    Pleyer, U.2    Yang, J.3
  • 165
    • 0033847776 scopus 로고    scopus 로고
    • Ballistic transfer of minimalistic immunologically defined expression constructs for IL4 and CTLA4 into the corneal epithelium in mice after orthotopic corneal allograft transplantation
    • Konig Merediz SA, Zhang EP, Wittig B, et al. Ballistic transfer of minimalistic immunologically defined expression constructs for IL4 and CTLA4 into the corneal epithelium in mice after orthotopic corneal allograft transplantation. Graefes Arch Clin Exp Ophthalmol 2000; 238:701-707.
    • (2000) Graefes Arch Clin Exp Ophthalmol , vol.238 , pp. 701-707
    • Konig Merediz, S.A.1    Zhang, E.P.2    Wittig, B.3
  • 166
    • 23444461955 scopus 로고    scopus 로고
    • Prolongation of sheep corneal allograft survival by transfer of the gene encoding ovine IL-12-p40 but not IL-4 to donor corneal endothe-lium
    • Klebe S, Coster DJ, Sykes PJ, et al. Prolongation of sheep corneal allograft survival by transfer of the gene encoding ovine IL-12-p40 but not IL-4 to donor corneal endothe-lium. J Immunol 2005;175:2219-2226.
    • (2005) J Immunol , vol.175 , pp. 2219-2226
    • Klebe, S.1    Coster, D.J.2    Sykes, P.J.3
  • 167
    • 0034994905 scopus 로고    scopus 로고
    • TNF receptor secretion after ex vivo adenoviral gene transfer to cornea and effect on in vivo graft survival
    • Rayner SA, Larkin DF, George AJ. TNF receptor secretion after ex vivo adenoviral gene transfer to cornea and effect on in vivo graft survival. Invest Ophthalmol Vis Sci 2001;42: 1568-1573.
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , pp. 1568-1573
    • Rayner, S.A.1    Larkin, D.F.2    George, A.J.3
  • 168
    • 84857358618 scopus 로고    scopus 로고
    • Expression of Stat3 and indoleamine 2, 3-dioxygenase in cornea keratocytes as factor of ocular immune privilege
    • Yang JW, Ham DS, Kim HW, et al. Expression of Stat3 and indoleamine 2, 3-dioxygenase in cornea keratocytes as factor of ocular immune privilege. Graefes Arch Clin Exp Ophthalmol 2012;250:25-31.
    • (2012) Graefes Arch Clin Exp Ophthalmol , vol.250 , pp. 25-31
    • Yang, J.W.1    Ham, D.S.2    Kim, H.W.3
  • 169
    • 35148819139 scopus 로고    scopus 로고
    • Expression of indoleamine 2, 3-dioxy-genase in human corneal cells as a local immunosup-pressive factor
    • Ryu YH, Kim JC. Expression of indoleamine 2, 3-dioxy-genase in human corneal cells as a local immunosup-pressive factor. Invest Ophthalmol Vis Sci 2007;48: 4148-4152.
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 4148-4152
    • Ryu, Y.H.1    Kim, J.C.2
  • 170
    • 0033519278 scopus 로고    scopus 로고
    • Inhibition of T cell proliferation by macrophage tryptophan catabolism
    • Munn DH, Shafizadeh E, Attwood JT, et al. Inhibition of T cell proliferation by macrophage tryptophan catabolism. J Exp Med 1999;189:1363-1372.
    • (1999) J Exp Med , vol.189 , pp. 1363-1372
    • Munn, D.H.1    Shafizadeh, E.2    Attwood, J.T.3
  • 171
    • 33644955010 scopus 로고    scopus 로고
    • Function of indoleamine 2, 3-dioxygenase in corneal allograft rejection and prolongation of allograft survival by over-expression
    • Beutelspacher SC, Pillai R, Watson MP, et al. Function of indoleamine 2, 3-dioxygenase in corneal allograft rejection and prolongation of allograft survival by over-expression. Eur J Immunol 2006;36:690-700.
    • (2006) Eur J Immunol , vol.36 , pp. 690-700
    • Beutelspacher, S.C.1    Pillai, R.2    Watson, M.P.3
  • 172
    • 84873547819 scopus 로고    scopus 로고
    • Pretreatment of rapamycin before allogenic corneal transplant promotes graft survival through increasing CD4()CD25()Foxp3() regulatory T cells
    • Wang X, Wang W, Xu J, et al. Pretreatment of rapamycin before allogenic corneal transplant promotes graft survival through increasing CD4()CD25()Foxp3() regulatory T cells. Exp Clin Transplant 2013;11:56-62.
    • (2013) Exp Clin Transplant , vol.11 , pp. 56-62
    • Wang, X.1    Wang, W.2    Xu, J.3
  • 173
    • 80052157997 scopus 로고    scopus 로고
    • Rapamycin and IL-2 reduce lethal acute graft-versus-host disease associated with increased expansion of donor type CD4CD25Foxp3 regulatory T cells
    • Shin HJ, Baker J, Leveson-Gower DB, et al. Rapamycin and IL-2 reduce lethal acute graft-versus-host disease associated with increased expansion of donor type CD4CD25Foxp3 regulatory T cells. Blood 2011;118: 2342-2350.
    • (2011) Blood , vol.118 , pp. 2342-2350
    • Shin, H.J.1    Baker, J.2    Leveson-Gower, D.B.3
  • 174
    • 37449030662 scopus 로고    scopus 로고
    • Preparation of rapamycin-loaded chitosan/PLA nanoparticles for immunosuppression in corneal transplantation
    • Yuan XB, Yuan YB, Jiang W, et al. Preparation of rapamycin-loaded chitosan/PLA nanoparticles for immunosuppression in corneal transplantation. Int J Pharm 2008;349:241-248.
    • (2008) Int J Pharm , vol.349 , pp. 241-248
    • Yuan, X.B.1    Yuan, Y.B.2    Jiang, W.3
  • 175
    • 33745154865 scopus 로고    scopus 로고
    • Keratocyte apoptosis and failure of corneal allografts
    • Beauregard C, Huq SO, Barabino S, et al. Keratocyte apoptosis and failure of corneal allografts. Transplantation 2006;81:1577-1582.
    • (2006) Transplantation , vol.81 , pp. 1577-1582
    • Beauregard, C.1    Huq, S.O.2    Barabino, S.3
  • 176
    • 0041342123 scopus 로고    scopus 로고
    • Predicting endo-thelial cell loss and long-term corneal graft survival
    • Armitage WJ, Dick AD, Bourne WM. Predicting endo-thelial cell loss and long-term corneal graft survival. Invest Ophthalmol Vis Sci 2003;44:3326-3331.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 3326-3331
    • Armitage, W.J.1    Dick, A.D.2    Bourne, W.M.3
  • 177
  • 178
    • 0030702084 scopus 로고    scopus 로고
    • Caspases: Intracellular signaling by proteolysis
    • Salvesen GS, Dixit VM. Caspases: intracellular signaling by proteolysis. Cell 1997;91:443-446.
    • (1997) Cell , vol.91 , pp. 443-446
    • Salvesen, G.S.1    Dixit, V.M.2
  • 180
    • 0031736865 scopus 로고    scopus 로고
    • Identification of the cornea-specific keratin 12 promoter by in vivo particle-mediated gene transfer
    • Shiraishi A, Converse RL, Liu CY, et al. Identification of the cornea-specific keratin 12 promoter by in vivo particle-mediated gene transfer. Invest Ophthalmol Vis Sci 1998;39:2554-2561.
    • (1998) Invest Ophthalmol Vis Sci , vol.39 , pp. 2554-2561
    • Shiraishi, A.1    Converse, R.L.2    Liu, C.Y.3
  • 181
    • 36148962376 scopus 로고    scopus 로고
    • Eye drop delivery of nano-polymeric micelle formulated genes with cornea-specific promoters
    • Tong YC, Chang SF, Liu CY, et al. Eye drop delivery of nano-polymeric micelle formulated genes with cornea-specific promoters. J Gene Med 2007;9:956-966.
    • (2007) J Gene Med , vol.9 , pp. 956-966
    • Tong, Y.C.1    Chang, S.F.2    Liu, C.Y.3
  • 182
    • 33746863749 scopus 로고    scopus 로고
    • Gene therapy progress and prospects: The eye
    • Bainbridge JW, Tan MH, Ali RR. Gene therapy progress and prospects: the eye. Gene Ther 2006;13: 1191-1197.
    • (2006) Gene Ther , vol.13 , pp. 1191-1197
    • Bainbridge, J.W.1    Tan, M.H.2    Ali, R.R.3
  • 183
  • 184
    • 70249143628 scopus 로고    scopus 로고
    • A steroid-inducible promoter for the cornea
    • Parker DG, Brereton HM, Klebe S, et al. A steroid-inducible promoter for the cornea. Br J Ophthalmol 2009; 93:1255-1259.
    • (2009) Br J Ophthalmol , vol.93 , pp. 1255-1259
    • Parker, D.G.1    Brereton, H.M.2    Klebe, S.3
  • 185
    • 84871910943 scopus 로고    scopus 로고
    • Dual suppression of hemangiogenesis and lymphangiogenesis by splice-shifting morpholinos targeting vascular endothelial growth factor receptor 2 (KDR)
    • Uehara H, Cho Y, Simonis J, et al. Dual suppression of hemangiogenesis and lymphangiogenesis by splice-shifting morpholinos targeting vascular endothelial growth factor receptor 2 (KDR). Faseb J 2013; 27:76-85.
    • (2013) Faseb J , vol.27 , pp. 76-85
    • Uehara, H.1    Cho, Y.2    Simonis, J.3
  • 186
    • 84863275784 scopus 로고    scopus 로고
    • Morpholino-mediated increase in soluble Flt-1 expression results in decreased ocular and tumor neovascularization
    • Owen LA, Uehara H, Cahoon J, et al. Morpholino-mediated increase in soluble Flt-1 expression results in decreased ocular and tumor neovascularization. PLoS One 2012;7:e33576.
    • (2012) PLoS One , vol.7
    • Owen, L.A.1    Uehara, H.2    Cahoon, J.3
  • 187
    • 84859253128 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor 1 morpholino decreases angiogen-esis in a murine corneal suture model
    • Cho YK, Uehara H, Young JR, et al. Vascular endothelial growth factor receptor 1 morpholino decreases angiogen-esis in a murine corneal suture model. Invest Ophthalmol Vis Sci 2012;53:685-692.
    • (2012) Invest Ophthalmol Vis Sci , vol.53 , pp. 685-692
    • Cho, Y.K.1    Uehara, H.2    Young, J.R.3
  • 188
    • 77649242176 scopus 로고    scopus 로고
    • Gene therapy for Leber's congenital amaurosis is safe and effective through 1.5 years after vector administration
    • Simonelli F, Maguire AM, Testa F, et al. Gene therapy for Leber's congenital amaurosis is safe and effective through 1.5 years after vector administration. Mol Ther 2010;18: 643-650.
    • (2010) Mol Ther , vol.18 , pp. 643-650
    • Simonelli, F.1    Maguire, A.M.2    Testa, F.3
  • 189
    • 85007302654 scopus 로고    scopus 로고
    • AAV2 gene therapy readministration in three adults with congenital blindness
    • Bennett J, Ashtari M, Wellman J, et al. AAV2 gene therapy readministration in three adults with congenital blindness. Sci Transl Med 2012;4:120ra115.
    • (2012) Sci Transl Med , vol.4
    • Bennett, J.1    Ashtari, M.2    Wellman, J.3
  • 190
    • 70350620424 scopus 로고    scopus 로고
    • Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: A phase 1 dose-escalation trial
    • Maguire AM, High KA, Auricchio A, et al. Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial. Lancet 2009;374:1597-1605.
    • (2009) Lancet , vol.374 , pp. 1597-1605
    • Maguire, A.M.1    High, K.A.2    Auricchio, A.3
  • 191
    • 84873830812 scopus 로고    scopus 로고
    • AAV9 targets cone photoreceptors in the nonhuman primate retina
    • Vandenberghe LH, Bell P, Maguire AM, et al. AAV9 targets cone photoreceptors in the nonhuman primate retina. PLoS One 2013;8:e53463.
    • (2013) PLoS One , vol.8
    • Vandenberghe, L.H.1    Bell, P.2    Maguire, A.M.3
  • 192
    • 83155177072 scopus 로고    scopus 로고
    • Dosage thresholds for AAV2 and AAV8 photoreceptor gene therapy in monkey
    • Vandenberghe LH, Bell P, Maguire AM, et al. Dosage thresholds for AAV2 and AAV8 photoreceptor gene therapy in monkey. Sci Transl Med 2011;3:88ra54.
    • (2011) Sci Transl Med , vol.3
    • Vandenberghe, L.H.1    Bell, P.2    Maguire, A.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.