Alterations in corneal stromal dendritic cell phenotype and distribution in inflammation

Archives of Ophthalmology

Volumn 121, Issue 8, 2003, Pages 1132-1140

  Hamrah, Pedram ^a   Liu, Ying ^c   Zhang, Qiang ^c   Dana, M Reza ^b  

^a University of Louisville School of Medicine   (United States)

^b SCHEPENS EYE RESEARCH INSTITUTE   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD11B ANTIGEN; CD86 ANTIGEN; GLYCOPROTEIN P 15095; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CELL MATURATION; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CORNEA STROMA; DENDRITIC CELL; IMMUNE RESPONSE; IMMUNOFLUORESCENCE; INFLAMMATION; KERATITIS; MACROPHAGE; MALE; MONOCYTE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

ANIMALS; ANTIGENS, CD; CORNEAL STROMA; DENDRITIC CELLS; DISEASE MODELS, ANIMAL; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; IMMUNOPHENOTYPING; KERATITIS; KERATOPLASTY, PENETRATING; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL;

EID: 0037497493     PISSN: 00039950     EISSN: None     Source Type: Journal    
DOI: 10.1001/archopht.121.8.1132     Document Type: Article

References (79)

1. Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature. 1998;392:245-252.
2. Hart DNJ. Dendritic cells: unique leukocyte populations which control the primary immune response. Blood. 1997;90:3245-3287.
3. Banchereau J, Briere F, Caux C, et al. Immunobiology of dendritic cells. Annu Rev Immunol. 2000;18:767-811.
4. Steinman RM. The dendritic cell system and its role in immunogenicity. Annu Rev Immunol. 1991;9:271-296.
5. Cella M, Sallusto F, Lanzavecchia A. Origin, maturation and antigen presentation function of dendritic cells. Curr Opin Immunol. 1997;9:10-16.
6. Callanan D, Peeler JS, Niederkorn JY. Characteristics of rejection of orthotopic corneal allografts in the rat. Transplantation. 1988;45:437-443.
7. McLeish W, Rubsamen P, Atherton SS, et al. Immunobiology of Langerhans cells on the ocular surface, II: role of central corneal Langerhans cells in stromal keratitis following experimental HSV-1 infection in mice. Reg Immunol. 1989;2:236-243.
8. Jager MJ, Bradley D, Atherton SS, Streilein JW. Presence of Langerhans cells in the central cornea linked to the development of ocular herpes in mice. Exp Eye Res. 1992;54:835-841.
9. Bergstresser PR, Fletcher CR, Streilein JW. Surface density of Langerhans cells in relation to rodent epidermal sites with special immunologic properties. J Invest Dermatol. 1980;74:77-80.
10. Jager MJ. Corneal Langerhans cells and ocular immunology. Reg Immunol. 1992;4:186-195.
11. Rowden G. Expression of Ia antigens on Langerhans cells in mice, guinea pigs, and man. J Invest Dermatol. 1980;75:22-31.
12. Treseler PA, Foulks GN, Sanfilippo F. The expression of HLA antigens by cells in the human cornea. Am J Ophthalmol. 1984;98:763-772.
13. Mayer DJ, Daar AS, Casey TA, Fabre JW. Localization of HLA-A, B, C and HLA-DR antigens in the human cornea: practical significance for grafting technique and HLA typing. Proceedings of the Ninth International Congress of the Transplantation Society, Brighton, England, August 23-27, 1983. Vol 15. Montreal, Quebec: Transplantation Society: 126-129.
14. Streilein JW, Toews GB, Bergstresser PR. Corneal allografts fail to express Ia antigens. Nature. 1979;282:320-321.
15. + Langerhans cells are required for induction of delayed-type hypersensitivity but not for cytotoxic T lymphocyte responses to alloantigens. J Immunol. 1986;136:4362-4371.
16. Pepose JS, Nestor MS, Gardner KM, Foos RY, Pettit TH. Composition of cellular infiltrates in rejected human corneal allografts. Graefes Arch Clin Exp Ophthalmol. 1985;222:128-133.
17. Streilein JW. Regional immunity and ocular immune privilege. Chem Immunol. 1999;73:11-38.
18. Gillette TE, Chandler JW, Greiner JV. Langerhans cells of the ocular surface. Ophthalmology. 1982;89:700-711.
19. Baudouin C, Fredj-Reygrobellet D, Gastaud P, Lapalus P. HLA DR and DQ distribution in normal human ocular structures. Curr Eye Res. 1988;7:903-911.
20. Klareskog L, Forsum U, Malmnäs T, Rask L, Peterson PA. Expression of Ia antigen-like molecules on cells in the corneal epithelium. Invest Ophthalmol Vis Sci. 1979;18:310-313.
21. Catry L, Van den Dord J, Foets B, Missotten L. Morphologic and immunophenotypic heterogeneity of corneal dendritic cells. Graefes Arch Clin Exp Ophthalmol. 1991;229:182-185.
22. Williams KA, Ash JK, Coster DJ. Histocompatibility antigen and passenger cell content of normal and diseased human cornea. Transplantation. 1985;39:265-269.
23. Williams KA, Mann TS, Lewis M, Coster DJ. The role of resident accessory cells in corneal allograft rejection in the rabbit. Transplantation. 1986;42:667-671.
24. Vantrappen L, Geboes K, Missotte L, Maudgal PC, Desmer V. Lymphocytes and Langerhans cells in the normal human cornea. Invest Ophthalmol Vis Sci. 1985;26:220-225.
25. Fujikawa LS, Colvin RB, Bhan AK, Fuller TC, Foster CS. Expression of HLA-A/B/C and -DR locus antigens on epithelial, stromal, and endothelial cells of the human cornea. Cornea. 1982;1:213-222.
26. Treseler PA, Sanfilippo F. The expression of major histocompatibility complex and leukocyte antigens by cells in the rat cornea. Transplantation. 1986;41:248-252.
27. Wang H, Kaplan HJ, Chan WC, Johnson M. The distribution and ontogeny of MHC antigen in murine ocular tissue. Invest Ophthalmol Vis Sci. 1987;28:1383-1389.
28. Pels E, van der Gaag R. HLA-A,B,C, and HLA-DR antigens and dendritic cells in fresh and organ culture preserved corneas. Cornea. 1984-1985;3:231-239.
29. Williamson JSP, DiMarco S, Streilein JW. Immunobiology of Langerhans cells on the ocular surface, I: Langerhans cells within the central cornea interfere with induction of anterior chamber associated immune deviation. Invest Ophthalmol Vis Sci. 1987;28:1527-1532.
30. Sano Y, Ksander BR, Streilein JW. Fate of orthotopic corneal allografts in eyes that cannot support anterior chamber-associated immune deviation induction. Invest Ophthalmol Vis Sci. 1995;36:2176-2185.
31. Niederkorn JY, Peeler JS, Mellon J. Phagocytosis of particulate antigens by corneal epithelial cells stimulates interleukin-1 secretion and migration of Langerhans cells into central cornea. Reg Immunol. 1989;2:83-90.
32. Liu Y, Hamrah P, Zhang Q, Taylor AW, Dana MR. Draining lymph nodes of corneal transplant hosts exhibit evidence for donor major histocompatibility complex (MHC) class II-positive dendritic cells derived from MHC class II-negative grafts. J Exp Med. 2002;195:259-268.
33. Hamrah P, Liu Y, Zhang Q, Dana MR. The corneal stroma is endowed with significant numbers of resident dendritic cells. Invest Ophthalmol Vis Sci. 2003;44:581-589.
34. Brissette-Storkus CS, Reynolds SM, Lepisto AJ, Hendricks RL. Identification of a novel macrophage population in the normal mouse corneal stroma. Invest Ophthalmol Vis Sci. 2002;43:2264-2271.
35. Hamrah P, Zhang Q, Liu Y, Dana MR. Novel characterization of MHC class II-negative population of resident corneal Langerhans cell-type dendritic cells. Invest Ophthalmol Vis Sci. 2002;43:639-646.
36. Liu Y, Hamrah P, Taylor AW, Dana MR. Resident corneal dendritic cells that migrate from corneal explants may mediate alloreactivity [ARVO abstract]. Invest Ophthalmol Vis Sci. 2002;43(suppl):S2264.
37. O'Brien TP, Li Q, Ashraf MF, Matteson DM, Stark WJ, Chan CC. Inflammatory response in the early stages of wound healing after excimer laser keratectomy. Arch Ophthalmol. 1998;116:1470-1474.
38. Li J, Xie L, Dong X. An experimental study on epikeratophakia [in Chinese]. Zhonghua Yan Ke Za Zhi. 1996;32:233-236.
39. Hazlett LD. Corneal and ocular surface histochemistry. Prog Histochem Cytochem. 1993;25:1-60.
40. Yamagami S, Dana MR. The critical role of draining lymph nodes in corneal allosensitization. Invest Ophthalmol Vis Sci. 2001;42:1293-1298.
41. Dekaris I, Zhu SN, Dana MR. TNF-α regulates corneal Langerhans cell migration. J Immunol. 1999;162:4235-4239.
42. Metley JP, Witmer Pack MD, Agger R, Crowley MT, Lawless D, Steinman RM. The distinct leukocyte integrins of mouse spleen dendritic cells as identified with new hamster monoclonal antibodies. J Exp Med. 1990;171:1753-1771.
43. Maraskovsky E, Brasel K, Teepe M, et al. Dramatic increase in the numbers of functionally mature dendritic cells in flt3 ligand-treated mice: multiple dendritic cell subpopulations identified. J Exp Med. 1996;184:1953-1962.
44. Pulendran B, Lingappa J, Kennedy MK, et al. Developmental pathways of dendritic cells in vivo. J Immunol. 1997;159:2222-2231.
45. Dana MR, Qian Y, Hamrah P. Twenty-five-year panorama of corneal immunology: emerging concepts in the immunopathogenesis of microbial keratitis, peripheral ulcerative keratitis, and corneal transplant rejection. Cornea. 2000;19:625-643.
46. Katami M. The mechanisms of corneal graft failure in the rat. Eye. 1995;9:197-207.
47. Cotran RS. Inflammation: historical perspectives. In: Gallin JI, Snyderman R, eds. Inflammation: Basic Principles and Clinical Correlates. Philadelphia, Pa: Lippincott Williams & Wilkins; 1999:5-10.
48. Caux C, Dezutter-Dambuyant C, Schmidt D, Banchereau J. GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cells. Nature. 1992;360:258-261.
49. Cumberbatch M, Dearman RJ, Kimber I. Langerhans cells require signals from both tumor necrosis factor-α and interleukin-1β for migration. Immunology. 1997;92:388-395.
50. Heufler C, Koch F, Schuler G. Granulocyte/macrophage colony-stimulating factor and interleukin 1 mediate the maturation of murine epidermal Langerhans cells into potent immunostimulatory dendritic cells. J Exp Med. 1988;167:700-705.
51. Inaba K, Inaba M, Romani N, et al. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J Exp Med. 1992;176:1693-1702.
52. Sekine-Okano M, Lucas R, Rungger D, et al. Expression and release of tumor necrosis factor-alpha by explants of mouse cornea. Invest Ophthalmol Vis Sci. 1996;37:1302-1310.
53. Cubitt CL, Lausch RN, Oakes JE. Differential regulation of granulocyte-macrophage colony-stimulating factor gene expression in human corneal cells by pro-inflammatory cytokines. J Immunol. 1994;153:232-240.
54. Dana MR, Yamada J, Streilein JW. Topical interleukin 1 receptor antagonist promotes corneal transplant survival. Transptantation. 1997;63:1501-1507.
55. Dana MR, Dai R, Zhu SN, Yamada J, Streilein JW. Interleukin-1 receptor antagonist suppresses Langerhans cell activity and promotes ocular immune privilege. Invest Ophthalmol Vis Sci. 1998;39:70-77.
56. Dana MR, Zhu SN, Yamada J. Topical modulation of interleukin-1 activity in corneal neovascularization. Cornea. 1998;17:403-409.
57. Dekaris I, Yamada J, Streilein JW, Dana MR. Effect of topical interleukin-1 receptor antagonist (IL-1ra) on corneal allograft transplant survival in presensitized hosts. Curr Eye Res. 1999;19:456-459.
58. Qian Y, Dekaris I, Yamagami S, Dana MR. Topical soluble tumor necrosis factor receptor type I suppresses ocular chemokine gene expression and rejection of allogeneic corneal transplants. Arch Ophthalmol. 2000;118:1666-1671.
59. Yamada J, Dana MR, Zhu SN, Alard P, Streilein JW. Interleukin 1 receptor antagonist suppresses allosensitization in corneal transplantation. Arch Ophthalmol. 1998;116:1351-1357.
60. Zhu S, Dekaris I, Duncker G, Dana MR. Early expression of proinflammatory cytokines interleukin-1 and tumor necrosis factor-alpha after corneal transplantation. J Interferon Cytokine Res. 1999;19:661-669.
61. Keane-Myers AM, Miyazaki D, Liu G, Dekaris I, Ono S, Dana MR. Prevention of allergic eye disease by treatment with IL-1 receptor antagonist. Invest Ophthalmol Vis Sci. 1999;40:3041-3046.
62. Springer TA. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell. 1994;76:301-314.
63. Zhu SN, Dana MR. Expression of cell adhesion molecules on limbal and neovascular endothelium in corneal inflammatory neovascularization. Invest Ophthalmol Vis Sci. 1999;40:1427-1434.
64. Zhu SN, Yamada J, Streilein JW, Dana MR. ICAM-1 deficiency suppresses host allosensitization and rejection of MHC-disparate corneal transplants. Transplantation. 2000;69:1008-1013.
65. Yamagami S, Miyazaki D, Ono S, Dana MR. Differential chemokine gene expression after corneal transplantation. Invest Ophthalmol Vis Sci. 1999;40:2892-2897.
66. Hamrah P, Liu Y, Yamagami S, Zhang Q, Vora S, Dana MR. Targeting the chemokine receptor CCR1 suppresses corneal alloimmunity and promotes allograft survival [abstract]. Clin Immunol 2001;99(suppl):S118.
67. Qian Y, Hamrah P, Boisgérault F, et al. Mechanisms of immunotherapeutic intervention by anti-CD154 (CD40L) antibody in high-risk corneal transplantation. J Interferon Cytokine Res. 2002;22:1217-1225.
68. Ruedl C, Koebel P, Bachmann M, Hess M, Karialainen K. Anatomical origin of dendritic cells determines their life span in peripheral lymph nodes. J Immunol 2000;165:4910-4916.
69. Thomson AW, Lu L, Murase N, Demetris AJ, Rao AS, Starzl TE. Microchimerism, dendritic cell progenitors and transplantation tolerance. Stem Cells. 1995;13:622-639.
70. Henke PK, Bergamini TM, Brittian KR, Polk HC. Prostaglandin E2 modulates MHC-II (Ia) suppression in biomaterial infection. J Surg Res. 1997;69:372-378.
71. Enk AH, Saloga J, Becker D, Mohamadzadeh M, Knop J. Induction of hapten-specific tolerance by interleukin-10 in vivo. J Exp Med. 1994;179:1397-1402.
72. Kawamura T, Furue M. Comparative analysis of B7-1 and B7-2 expression in Langerhans cells: differential regulation by T helper type 1 and T helper type 2 cytokines. Eur J Immunol. 1995;25:1913-1917.
73. Zhang Y, Zhang Y-Y, Ogata M, et al. Transforming growth factor-β1 polarizes murine hematopoietic progenitor cells to generate Langerhans cell-like dendritic cells through a monocyte/macrophage differentiation pathway. Blood. 1999;93:1208-1220.
74. Koppelmann B, Neefjes JJ, de Vries JE, de Waal Malefyl R. Interleukin-10 down-regulates MHC class II αβ peptide complexes at the plasma membrane of monocytes by affecting arrival and recycling. Immunity. 1997;7:861-871.
75. Snyder DS, Beller DI, Unanue ER. Prostaglandins modulate macrophage Ia expression. Nature. 1982;299:163-165.
76. Sano Y, Ksander BR, Streilein JW. Langerhans cells, orthotopic corneal allografts, and direct and indirect pathways of T-cell allorecognition. Invest Ophthalmol Vis Sci. 2000;41:1422-1431.
77. Snell GD. The homograft reaction. Annu Rev Microbiol. 1957;11:439-458.
78. Lafferty KJ, Prowse SJ, Simeonovic CJ, Warren HS. Immunobiology of tissue transplantation: a return to the passenger leukocyte concept. Annu Rev Immunol. 1983;1:143-173.
79. Ross J, Callanan D, Kunz H, Niederkorn JY. Evidence that the fate of class II-disparate corneal grafts is determined by the timing of class II expression. Transplantation. 1991;51:532-536.