Ex vivo adenovirus-mediated gene transfer and immunomodulatory protein production in human cornea

Gene Therapy

Volumn 4, Issue 7, 1997, Pages 639-647

  Oral, H B ^a   Larkin, D F P ^a,b   Fehervari, Z ^a,c   Byrnes, A P ^d,e   Rankin, A M ^f   Haskard, D O ^a   Wood, M J A ^d   Dallman, M J ^f   George, A J T ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c GLAXOSMITHKLINE   (United Kingdom)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e JOHNS HOPKINS UNIVERSITY   (United States)

^f IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

CTLA 4 Ig; Endothelium; RT PCR; Transplantation; galactosidase

Indexed keywords

B7 ANTIGEN; BETA GALACTOSIDASE; HYBRID PROTEIN; MESSENGER RNA; T LYMPHOCYTE RECEPTOR; VIRUS DNA;

ADENOVIRUS; ARTICLE; CONTROLLED STUDY; CORNEA; CORNEA ENDOTHELIUM; CYTOMEGALOVIRUS; EXPRESSION VECTOR; GENE EXPRESSION; GENE TRANSFER; HUMAN; HUMAN TISSUE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA TRANSCRIPTION; ROUS SARCOMA ONCOVIRUS; VIRUS RECOMBINANT;

ADENOVIRIDAE; CYTOMEGALOVIRUS; DNA VIRUSES; ONCOVIRINAE; ROUS SARCOMA VIRUS;

EID: 0030840092     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3300443     Document Type: Article

References (38)

1. Price FW, Whitson WE, Collins KS, Marks RG. Five-year corneal graft survival. Arch Ophthalmol 1993; 111: 799-805.
2. Vail A et al. Corneal transplantation in the United Kindom and Republic of Ireland. Br J Ophthalmol 1993; 77: 650-652.
3. Bourne FW, Hodge DO, Nelson LR. Corneal endothelium five years after transplantation. Am J Ophthalmol 1994; 118: 185-196.
4. Larkin DFP et al. Adenovirus-mediated gene delivery to the corneal endothehum. Transplantation 1996; 61: 363-370.
5. Fehervari Z et al. Gene transfer to ex vivo stored corneas. Cornea (in press).
6. Schofield JP, Caskey CT. Non-viral approaches to gene therapy. Br Med Bull 1995; 51: 56-71.
7. Khodadoust AA, Silverstein AM. Transplantation and rejection of individual cell layers of the cornea. Invest Ophthalmol 1969; 8: 180-195.
8. Williams KA et al. Patterns of corneal graft rejection in the rabbit and reversal of rejection with monoclonal antibodies. Transplantation 1992; 54: 38-43.
9. Larkin DFP, Calder VL, Lightman SL. Identification and characterisation of cells infiltrating the graft and aqueous humour in rat corneal allograft rejection. Clin Exp Immunol 1997; 107: 381-391.
10. Mueller DL, Jenkins MK, Schwartz RH. Clonal expansion versus functional clonal mactivation: a costimulatury signalling pathway determines the outcome of T cell antigen receptor occupancy. Annu Rev Immunol 1989; 7: 445-480.
11. Linsley PS et al. Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation. J Exp Med 1991; 173: 721-730.
12. Gimmi CD et al. B-cell surface antigen B7 provides a costimulatory signal that induces T cells to proliferate and secrete interleukin 2. Proc Natl Acad Sci USA 1991; 88: 6575-6579.
13. Harding FA et al. CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T cell clones. Nature 1992; 356: 607-609.
14. Tan P et al. Induction of alloantigen-specific hyporesponsiveness in human T lymphocytes by blocking interaction of CD28 with its natural ligand B7/BB1. J Exp Med 1993; 177 165-173.
15. Boussiotis VA et al. B7 but not intracellular adhesion molecule-1 costimulation prevents the induction of human alloantigen-specific tolerance. J Exp Med 1993; 178: 1753-1763.
16. Linsley PS et al. CTLA-4 is a second receptor for the B cell activation antigen B7. J Exp Med 1991; 174: 561-569.
17. Harper K et al. CTLA-4 and CD28 activated lymphocyte molecules are closely related in both mouse and human as to sequence, message expression, gene structure, and chromosomal location. J Immunol 1991; 147: 1037-1044.
18. Lenschaw DJ et al. Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA4Ig Science 1992; 257: 789-792.
19. Lin H et al. Long-term acceptance of major histocompatibility complex mismatched cardiac allografts induced by CTLA-4 Ig plus donor specific transfusion. J Exp Med 1993; 178: 1801-1806.
20. Pearson TC et al. Transplantation tolerance induced by CTLA-4 Ig. Transplantation 1994; 57: 1701-1706
21. Mashhour B, Couton D, Perricaudet M, Briand P In vivo adenovirus-mediated gene transfer into ocular tissues. Gene Therapy 1994; 1: 122-126.
22. Feldman ST et al. Gene transfer to the anterior segment of the eye by infection with recombinant viral vector. Invest Opthalmol Vis Sci 1994; 35 (Suppl.): 1383 (Abstr).
23. Budenz DL, Bennett J, Alonso L, Maguire A. In vivo gene transfer into murine corneal endothelial and trabecular meshwork cells. Invest Opthalmol Vis Sci 1995; 36: 2211-2215.
24. Chodosh J, Miller D, Stoop WG, Pflugfelder SC. Adenovirus epithelial keratitis. Cornea 1995; 14: 167-174.
25. Guzman RJ et al. Efficient and selective adenovirus-mediated gene transfer into vascular neointima. Circulation 1993; 88: 2838-2848.
26. Larkin DFP. Corneal allograft rejection. Br J Ophthalmol 1994; 78: 649-652.
27. Edgell C-JS, McDonald CC, Graham JB. Permanent cell line expressing human factor VIII-related antigen established by hybridization. Proc Natl Acad Sci USA 1983; 80: 3734-3737.
28. - T cells is dependent on B7 (CD80), augmented by CD58, but relatively uninfluenced by CD54 expression. Int Immunol 1995; 7: 1505-1513.
29. Graham FL, Smiley J, Russell WC, Nairn R. Characteristics of a human cell line transformed by DNA from human adenovirus type 5. J Gen Viral 1977, 36: 59-74.
30. Byrnes AP, Rusby JE, Wood MJA, Charlton HM. Adenovirus gene transfer causes inflammation in the brain. Neuroscience 1995; 66: 1015-1024.
31. McGrory WJ, Bautista DS, Graham FL. A simple technique for the rescue of early region I mutations into infectious human adenovirus type 5. Virology 1988; 163: 614-617.
32. Simmons DL. Cloning cell surface molecules by transient expression in mammalian cells. In: Hartley D (ed). Cellular Interactions in Development. Oxford University Press: Oxford, 1993, pp 93-127.
33. Green M, Wold WSM. Human adenoviruses: growth, purification and transfection assay. Meth Enzymol 1979; 58: 434-435.
34. Sanes JR, Rubinstein JLR, Nicholas J-F. Use of recombinant retroviruses to study post-implantation cell image in mouse embryos. EMBO J 1986; 5: 3133-3142.
35. Krezse G-B. Methods for protein determination. In: Bergmeyer J, Grassl M (eds). Methods of Enzymatic Analysis: Samples, Reagents, Assessment of Results, vol 2. Verlag Chemie: Weinheim, 1983, pp 89-92.
36. Zhang M et al. Interleukin-12 at the site of disease in tuberculosis. J Clin Invest 1994; 93: 1733-1739.
37. Moore DD. Preparation of genomic DNA. In: Ausubel FM et al (eds). Current Protocols in Molecular Biology, vol 1. John Wiley: New York, NY, 1992, pp 2.2.1-2.2.3.
38. Csete ME et al. Efficient gene transfer to pancreatic islets mediated by adenoviral vectors. Transplantation 1995; 59: 263-268.