Anti-apoptotic gene therapy prolongs survival of corneal endothelial cells during storage

Gene Therapy

Volumn 18, Issue 8, 2011, Pages 778-787

  Fuchsluger, T A ^a,b   Jurkunas, U ^a,c   Kazlauskas, A ^a   Dana, R ^a,c  

^a SCHEPENS EYE RESEARCH INSTITUTE   (United States)

^b UNIVERSITY HOSPITAL ESSEN   (Germany)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

apoptosis; cornea; storage; transplantation

Indexed keywords

BACULOVIRUS VECTOR; CASPASE 3; LENTIVIRUS VECTOR; RECOMBINANT PROTEIN; RECOMBINANT PROTEIN BCL XL; RECOMBINANT PROTEIN P35; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL BASED GENE THERAPY; CELL DENSITY; CELL STRUCTURE; CELL SURVIVAL; CONTROLLED STUDY; CORNEA ENDOTHELIUM; CORNEA PRESERVATION; CORNEA TRANSPLANTATION; CORNEAL ENDOTHELIAL CELL LOSS; DONOR; EYEBANK; GENE EXPRESSION; GRAFT FAILURE; HUMAN; HUMAN CELL; IN VITRO GENE TRANSFER; NICK END LABELING; OUTCOME ASSESSMENT; PRIORITY JOURNAL;

BCL-X PROTEIN; CASPASE 3; CELL SURVIVAL; CORNEAL TRANSPLANTATION; CRYOPRESERVATION; ENDOTHELIUM, CORNEAL; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; LENTIVIRUS; TISSUE PRESERVATION; VIRAL PROTEINS;

MAMMALIA;

EID: 80051802103     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2011.20     Document Type: Article

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