CD4+ T-cell-mediated mechanisms of corneal allograft rejection: Role of Fas-induced apoptosis

Transplantation

Volumn 79, Issue 1, 2005, Pages 23-31

  Hegde, Sushma ^b   Beauregard, Clay ^a   Mayhew, Elizabeth ^a   Niederkorn, Jerry Y ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Apoptosis; CD4+ T helper cells; Corneal allograft; Immune privilege

Indexed keywords

CD4 ANTIGEN; FAS ANTIBODY; LIPOCORTIN 5;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BINDING ASSAY; CELL INTERACTION; CONTROLLED STUDY; CORNEA TRANSPLANTATION; EFFECTOR CELL; ENDOTHELIUM CELL; EPITHELIUM CELL; FLUORESCENCE ACTIVATED CELL SORTING; GRAFT REJECTION; IMMUNOTHERAPY; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SLIT LAMP; T LYMPHOCYTE;

ANIMALS; ANTIGENS, CD95; APOPTOSIS; CD4-POSITIVE T-LYMPHOCYTES; CORNEA; CORNEAL TRANSPLANTATION; FEMALE; GRAFT REJECTION; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; TRANSPLANTATION, HOMOLOGOUS;

EID: 12344251710     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.TP.0000147196.79546.69     Document Type: Article

References (38)

1. Streilein JW. Ocular immune privilege: therapeutic opportunities from an experiment of nature. Nat Rev Immunol 2003; 3: 879.
2. Niederkorn JY. The immune privilege of corneal grafts. J Leukoc Biol 2003; 74: 167.
3. Group CCTSR. The collaborative corneal transplantation studies (CCTS). Effectiveness of histocompatibility matching in high-risk corneal transplantation. Arch Ophthalmol 1992; 110: 1392.
4. Larkin DF, Calder VL, Lightman SL. Identification and characterization of cells infiltrating the graft and aqueous humour in rat corneal allograft rejection. Clin Exp Immunol 1997; 107: 381.
5. Larkin DF, Alexander RA, Cree IA. Infiltrating inflammatory cell phenotypes and apoptosis in rejected human corneal allografts. Eye 1997; 11:68.
6. Pepose JS, Nestor MS, Gardner KM, et al. Composition of cellular infiltrates in rejected human corneal allografts. Graefes Arch Clin Exp Ophthalmol 1985; 222: 128.
7. Williams KA, White MA, Ash JK, et al. Leukocytes in the graft bed associated with corneal graft failure. Analysis by immunohistology and actuarial graft survival. Ophthalmology 1989; 96: 38.
8. He YG, Ross J, Niederkorn JY. Promotion of murine orthotopic corneal allograft survival by systemic administration of anti-CD4 monoclonal antibody. Invest Ophthalmol Vis Sci 1991; 32: 2723.
9. Ayliffe W, Alam Y, Bell EB, et al. Prolongation of rat corneal graft survival by treatment with anti-CD4 monoclonal antibody. Br J Ophthalmol 1992; 76: 602.
10. Yamada J, Kurimoto I, Streilein JW. Role of CD4+ T cells in immunobiology of orthotopic corneal transplants in mice. Invest Ophthalmol Vis Sci 1999; 40: 2614.
11. Abbas AK, Murphy KM, Sher A. Functional diversity of helper T lymphocytes. Nature 1996; 383: 787.
12. Shresta S, Pham CT, Thomas DA, et al. How do cytotoxic lymphocytes kill their targets? Curr Opin Immunol 1998; 10: 581.
13. He YG, Niederkorn JY. Depletion of donor-derived Langerhans cells promotes corneal allograft survival. Cornea 1996; 15: 82.
14. Ma D, Mellon J, Niederkorn JY. Conditions affecting enhanced corneal allograft survival by oral immunization. Invest Ophthalmol Vis Sci 1998; 39: 1835.
15. He YG, McCulley JP. Growing human corneal epithelium on collagen shield and subsequent transfer to denuded cornea in vitro. Curr Eye Res 1991; 10: 851.
16. Yue BY, Sugar J, Gilboy JE, et al. Growth of human corneal endothelial cells in culture. Invest Ophthalmol Vis Sci 1989; 30: 248.
17. Wilson SE, Weng J, Blair S, et al. Expression of E6/E7 or SV40 large T antigencoding oncogenes in human corneal endothelial cells indicates regulated highproliferative capacity. Invest Ophthalmol Vis Sci 1995; 36: 32.
18. van Klink F, Taylor WM, Alizadeh H, et al. The role of macrophages in Acanthamoeba keratitis. Invest Ophthalmol Vis Sci 1996; 37: 1271.
19. Skelsey ME, Mayhew E, Niederkorn JY. Splenic B cells act as antigen presenting cells for the induction of anterior chamber-associated immune deviation. Invest Ophthalmol Vis Sci 2003; 44: 5242.
20. Dvorak HF, Galli SJ, Dvorak AM. Cellular and vascular manifestations of cell-mediated immunity. Hum Pathol 1986; 17: 122.
21. Yamamoto N, Einaga-Naito K, Kuriyama M, et al. Cellular basis of skin allograft rejection in mice: specific lysis of allogeneic skin components by non-T cells. Transplantation 1998; 65: 818.
22. Van der Veen G, Broersma L, Dijkstra CD, et al. Prevention of corneal allograft rejection in rats treated with subconjunctival injections of liposomes containing dichloromethylene diphosphonate. Invest Ophthalmol Vis Sci 1994; 35: 3505.
23. Wilson SE, Li Q, Weng J, et al. The Fas- Fas ligand system and other modulators of apoptosis in the cornea. Invest Ophthalmol Vis Sci 1996; 37: 1582.
24. Ogasawara J, Watanabe-Fukunaga R, Adachi M, et al. Lethal effect of the anti-Fas antibody in mice. Nature 1993; 364: 806.
25. Reference deleted.
26. Hegde S, Niederkorn JY. The role of cytotoxic T lymphocytes in corneal allograft rejection. Invest Ophthalmol Vis Sci 2000; 41: 3341.
27. Hegde S, Mellon JK, Hargrave SL, et al. Effect of alloantibodies on corneal allograft survival. Invest Ophthalmol Vis Sci 2002; 43: 1012.
28. Goslings WR, Yamada J, Dana MR, et al. Corneal transplantation in antibody-deficient hosts. Invest Ophthalmol Vis Sci 1999; 40: 250.
29. Chu JL, Drappa J, Parnassa A, et al. The defect in Fas mRNA expression in MRL/lpr mice is associated with insertion of the retrotransposon, ETn. J Exp Med 1993; 178: 723.
30. Nagata S, Golstein P. The Fas death factor. Science 1995; 267: 1449.
31. Seino K, Kayagaki N, Bashuda H, et al. Contribution of Fas ligand to cardiac allograft rejection. Int Immunol 1996; 8: 1347.
32. Selvaggi G, Ricordi C, Podack ER, et al. The role of the perforin and Fas pathways of cytotoxicity in skin graft rejection. Transplantation 1996; 62: 1912.
33. Smith CA, Farrah T, Goodwin RG. The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and death. Cell 1994; 76: 959.
34. Miwa K, Asano M, Horai R, et al. Caspase 1-independent IL-1beta release and inflammation induced by the apoptosis inducer Fas ligand. Nat Med 1998; 4: 1287.
35. Gregory MS, Repp AC, Holhbaum AM, et al. Membrane Fas ligand activates innate immunity and terminates ocular immune privilege. J Immunol 2002; 169: 2727.
36. Takamizawa S, Okamoto S, Wen J, et al. Overexpression of Fas-ligand by neuroblastoma: a novel mechanism of tumor-cell killing. J Pediatr Surg 2000; 35: 375.
37. Yamada J, Streilein JW, Dana MR. Role of tumor necrosis factor receptors TNFR-I (P55) and TNFR-II (P75) in corneal transplantation. Transplantation 1999; 68: 944.
38. Hargrave SL, Hay C, Mellon J, et al. Fate of MHC-matched corneal allografts in Th1-deficient hosts. Invest Ophthalmol Vis Sci 2004; 45: 1188.