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Volumn 51, Issue 4, 2013, Pages 264-270

Notch and Wnt signaling in the emergence of hematopoietic stem cells

Author keywords

AGM; Embryonic hematopoiesis; Hematopoiesis; HSC; Notch; Wnt

Indexed keywords

ANKYRIN; BETA CATENIN; DELTA LIKE LIGAND; EPIDERMAL GROWTH FACTOR; JAGGED1; NOTCH RECEPTOR; NUCLEAR FACTOR; NUCLEAR FACTOR RBPJ; PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN;

EID: 84886308051     PISSN: 10799796     EISSN: 10960961     Source Type: Journal    
DOI: 10.1016/j.bcmd.2013.07.005     Document Type: Article
Times cited : (59)

References (141)
  • 1
    • 38349179230 scopus 로고    scopus 로고
    • Of lineage and legacy: the development of mammalian hematopoietic stem cells
    • Dzierzak E., Speck N.A. Of lineage and legacy: the development of mammalian hematopoietic stem cells. Nat. Immunol. 2008, 9(2):129-136.
    • (2008) Nat. Immunol. , vol.9 , Issue.2 , pp. 129-136
    • Dzierzak, E.1    Speck, N.A.2
  • 2
    • 0033405452 scopus 로고    scopus 로고
    • Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse
    • Palis J., et al. Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse. Development 1999, 126(22):5073-5084.
    • (1999) Development , vol.126 , Issue.22 , pp. 5073-5084
    • Palis, J.1
  • 3
    • 33846907357 scopus 로고    scopus 로고
    • The megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and of definitive hematopoiesis
    • Tober J., et al. The megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and of definitive hematopoiesis. Blood 2007, 109(4):1433-1441.
    • (2007) Blood , vol.109 , Issue.4 , pp. 1433-1441
    • Tober, J.1
  • 4
    • 0030946401 scopus 로고    scopus 로고
    • Engraftment of embryonic hematopoietic cells in conditioned newborn recipients
    • Yoder M.C., Hiatt K. Engraftment of embryonic hematopoietic cells in conditioned newborn recipients. Blood 1997, 89(6):2176-2183.
    • (1997) Blood , vol.89 , Issue.6 , pp. 2176-2183
    • Yoder, M.C.1    Hiatt, K.2
  • 5
    • 0030879733 scopus 로고    scopus 로고
    • Characterization of definitive lymphohematopoietic stem cells in the day 9 murine yolk sac
    • Yoder M.C., et al. Characterization of definitive lymphohematopoietic stem cells in the day 9 murine yolk sac. Immunity 1997, 7(3):335-344.
    • (1997) Immunity , vol.7 , Issue.3 , pp. 335-344
    • Yoder, M.C.1
  • 6
    • 34247601504 scopus 로고    scopus 로고
    • Cell tracing shows the contribution of the yolk sac to adult haematopoiesis
    • Samokhvalov I.M., Samokhvalova N.I., Nishikawa S. Cell tracing shows the contribution of the yolk sac to adult haematopoiesis. Nature 2007, 446(7139):1056-1061.
    • (2007) Nature , vol.446 , Issue.7139 , pp. 1056-1061
    • Samokhvalov, I.M.1    Samokhvalova, N.I.2    Nishikawa, S.3
  • 7
    • 82755185961 scopus 로고    scopus 로고
    • Erythroid/myeloid progenitors and hematopoietic stem cells originate from distinct populations of endothelial cells
    • Chen M.J., et al. Erythroid/myeloid progenitors and hematopoietic stem cells originate from distinct populations of endothelial cells. Cell Stem Cell 2011, 9(6):541-552.
    • (2011) Cell Stem Cell , vol.9 , Issue.6 , pp. 541-552
    • Chen, M.J.1
  • 8
    • 0029980131 scopus 로고    scopus 로고
    • Two distinct endothelial lineages in ontogeny, one of them related to hemopoiesis
    • Pardanaud L., et al. Two distinct endothelial lineages in ontogeny, one of them related to hemopoiesis. Development 1996, 122(5):1363-1371.
    • (1996) Development , vol.122 , Issue.5 , pp. 1363-1371
    • Pardanaud, L.1
  • 9
    • 0034813102 scopus 로고    scopus 로고
    • Intraembryonic, but not yolk sac hematopoietic precursors, isolated before circulation, provide long-term multilineage reconstitution
    • Cumano A., et al. Intraembryonic, but not yolk sac hematopoietic precursors, isolated before circulation, provide long-term multilineage reconstitution. Immunity 2001, 15(3):477-485.
    • (2001) Immunity , vol.15 , Issue.3 , pp. 477-485
    • Cumano, A.1
  • 10
    • 56549101520 scopus 로고    scopus 로고
    • Fate tracing reveals the endothelial origin of hematopoietic stem cells
    • Zovein A.C., et al. Fate tracing reveals the endothelial origin of hematopoietic stem cells. Cell Stem Cell 2008, 3(6):625-636.
    • (2008) Cell Stem Cell , vol.3 , Issue.6 , pp. 625-636
    • Zovein, A.C.1
  • 11
    • 60149100010 scopus 로고    scopus 로고
    • Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter
    • Chen M.J., et al. Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter. Nature 2009, 457(7231):887-891.
    • (2009) Nature , vol.457 , Issue.7231 , pp. 887-891
    • Chen, M.J.1
  • 12
    • 0028467947 scopus 로고
    • Development of hematopoietic stem cell activity in the mouse embryo
    • Muller A.M., et al. Development of hematopoietic stem cell activity in the mouse embryo. Immunity 1994, 1(4):291-301.
    • (1994) Immunity , vol.1 , Issue.4 , pp. 291-301
    • Muller, A.M.1
  • 13
    • 0030595341 scopus 로고    scopus 로고
    • Definitive hematopoiesis is autonomously initiated by the AGM region
    • Medvinsky A., Dzierzak E. Definitive hematopoiesis is autonomously initiated by the AGM region. Cell 1996, 86(6):897-906.
    • (1996) Cell , vol.86 , Issue.6 , pp. 897-906
    • Medvinsky, A.1    Dzierzak, E.2
  • 14
    • 0034214284 scopus 로고    scopus 로고
    • Definitive hematopoietic stem cells first develop within the major arterial regions of the mouse embryo
    • de Bruijn M.F., et al. Definitive hematopoietic stem cells first develop within the major arterial regions of the mouse embryo. EMBO J. 2000, 19(11):2465-2474.
    • (2000) EMBO J. , vol.19 , Issue.11 , pp. 2465-2474
    • de Bruijn, M.F.1
  • 15
    • 14644416569 scopus 로고    scopus 로고
    • The placenta is a niche for hematopoietic stem cells
    • Gekas C., et al. The placenta is a niche for hematopoietic stem cells. Dev. Cell 2005, 8(3):365-375.
    • (2005) Dev. Cell , vol.8 , Issue.3 , pp. 365-375
    • Gekas, C.1
  • 16
    • 84855487703 scopus 로고    scopus 로고
    • Highly potent human hematopoietic stem cells first emerge in the intraembryonic aorta-gonad-mesonephros region
    • Ivanovs A., et al. Highly potent human hematopoietic stem cells first emerge in the intraembryonic aorta-gonad-mesonephros region. J. Exp. Med. 2011, 208(12):2417-2427.
    • (2011) J. Exp. Med. , vol.208 , Issue.12 , pp. 2417-2427
    • Ivanovs, A.1
  • 17
    • 70349308500 scopus 로고    scopus 로고
    • Human placenta is a potent hematopoietic niche containing hematopoietic stem and progenitor cells throughout development
    • Robin C., et al. Human placenta is a potent hematopoietic niche containing hematopoietic stem and progenitor cells throughout development. Cell Stem Cell 2009, 5(4):385-395.
    • (2009) Cell Stem Cell , vol.5 , Issue.4 , pp. 385-395
    • Robin, C.1
  • 18
    • 34547174800 scopus 로고    scopus 로고
    • Functional identification of the hematopoietic stem cell niche in the ventral domain of the embryonic dorsal aorta
    • Taoudi S., Medvinsky A. Functional identification of the hematopoietic stem cell niche in the ventral domain of the embryonic dorsal aorta. Proc. Natl. Acad. Sci. U. S. A. 2007, 104(22):9399-9403.
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , Issue.22 , pp. 9399-9403
    • Taoudi, S.1    Medvinsky, A.2
  • 19
    • 79959418692 scopus 로고    scopus 로고
    • Three-dimensional imaging of whole midgestation murine embryos shows an intravascular localization for all hematopoietic clusters
    • Yokomizo T., et al. Three-dimensional imaging of whole midgestation murine embryos shows an intravascular localization for all hematopoietic clusters. Blood 2011, 117(23):6132-6134.
    • (2011) Blood , vol.117 , Issue.23 , pp. 6132-6134
    • Yokomizo, T.1
  • 20
    • 0016811829 scopus 로고
    • Role of stem cell migration in initiation of mouse foetal liver haemopoiesis
    • Johnson G.R., Moore M.A. Role of stem cell migration in initiation of mouse foetal liver haemopoiesis. Nature 1975, 258(5537):726-728.
    • (1975) Nature , vol.258 , Issue.5537 , pp. 726-728
    • Johnson, G.R.1    Moore, M.A.2
  • 21
    • 0019849760 scopus 로고
    • Differentiation of the mouse hepatic primordium. II. Extrinsic origin of the haemopoietic cell line
    • Houssaint E. Differentiation of the mouse hepatic primordium. II. Extrinsic origin of the haemopoietic cell line. Cell Differ. 1981, 10(5):243-252.
    • (1981) Cell Differ. , vol.10 , Issue.5 , pp. 243-252
    • Houssaint, E.1
  • 22
    • 0034177619 scopus 로고    scopus 로고
    • Expansion of hematopoietic stem cells in the developing liver of a mouse embryo
    • Ema H., Nakauchi H. Expansion of hematopoietic stem cells in the developing liver of a mouse embryo. Blood 2000, 95(7):2284-2288.
    • (2000) Blood , vol.95 , Issue.7 , pp. 2284-2288
    • Ema, H.1    Nakauchi, H.2
  • 23
    • 84857873445 scopus 로고    scopus 로고
    • Hematopoietic stem cell subtypes expand differentially during development and display distinct lymphopoietic programs
    • Benz C., et al. Hematopoietic stem cell subtypes expand differentially during development and display distinct lymphopoietic programs. Cell Stem Cell 2012, 10(3):273-283.
    • (2012) Cell Stem Cell , vol.10 , Issue.3 , pp. 273-283
    • Benz, C.1
  • 24
    • 84876859901 scopus 로고    scopus 로고
    • The migration of hematopoietic progenitors from the fetal liver to the fetal bone marrow: Lessons learned and possible clinical applications
    • Ciriza J., et al. The migration of hematopoietic progenitors from the fetal liver to the fetal bone marrow: Lessons learned and possible clinical applications. Exp. Hematol. 2013, 41(5):411-423.
    • (2013) Exp. Hematol. , vol.41 , Issue.5 , pp. 411-423
    • Ciriza, J.1
  • 25
    • 64249172203 scopus 로고    scopus 로고
    • The canonical Notch signaling pathway: unfolding the activation mechanism
    • Kopan R., Ilagan M.X. The canonical Notch signaling pathway: unfolding the activation mechanism. Cell 2009, 137(2):216-233.
    • (2009) Cell , vol.137 , Issue.2 , pp. 216-233
    • Kopan, R.1    Ilagan, M.X.2
  • 26
    • 84859608557 scopus 로고    scopus 로고
    • Hematopoietic stem cells: to be or Notch to be
    • Bigas A., Espinosa L. Hematopoietic stem cells: to be or Notch to be. Blood 2012, 119(14):3226-3235.
    • (2012) Blood , vol.119 , Issue.14 , pp. 3226-3235
    • Bigas, A.1    Espinosa, L.2
  • 27
    • 0026086474 scopus 로고
    • Specific EGF repeats of Notch mediate interactions with Delta and Serrate: implications for Notch as a multifunctional receptor
    • Rebay I., et al. Specific EGF repeats of Notch mediate interactions with Delta and Serrate: implications for Notch as a multifunctional receptor. Cell 1991, 67(4):687-699.
    • (1991) Cell , vol.67 , Issue.4 , pp. 687-699
    • Rebay, I.1
  • 28
    • 0034038237 scopus 로고    scopus 로고
    • The Abruptex domain of Notch regulates negative interactions between Notch, its ligands and Fringe
    • de Celis J.F., Bray S.J. The Abruptex domain of Notch regulates negative interactions between Notch, its ligands and Fringe. Development 2000, 127(6):1291-1302.
    • (2000) Development , vol.127 , Issue.6 , pp. 1291-1302
    • de Celis, J.F.1    Bray, S.J.2
  • 29
    • 84870224298 scopus 로고    scopus 로고
    • A mutation in EGF repeat-8 of Notch discriminates between Serrate/Jagged and Delta family ligands
    • Yamamoto S., et al. A mutation in EGF repeat-8 of Notch discriminates between Serrate/Jagged and Delta family ligands. Science 2012, 338(6111):1229-1232.
    • (2012) Science , vol.338 , Issue.6111 , pp. 1229-1232
    • Yamamoto, S.1
  • 30
    • 0037074006 scopus 로고    scopus 로고
    • Regulation of notch signaling by o-linked fucose
    • Okajima T., Irvine K.D. Regulation of notch signaling by o-linked fucose. Cell 2002, 111(6):893-904.
    • (2002) Cell , vol.111 , Issue.6 , pp. 893-904
    • Okajima, T.1    Irvine, K.D.2
  • 31
    • 79955561765 scopus 로고    scopus 로고
    • Regulation of mammalian Notch signaling and embryonic development by the protein O-glucosyltransferase Rumi
    • Fernandez-Valdivia R., et al. Regulation of mammalian Notch signaling and embryonic development by the protein O-glucosyltransferase Rumi. Development 2011, 138(10):1925-1934.
    • (2011) Development , vol.138 , Issue.10 , pp. 1925-1934
    • Fernandez-Valdivia, R.1
  • 32
    • 0001395691 scopus 로고    scopus 로고
    • Fringe is a glycosyltransferase that modifies Notch
    • Moloney D.J., et al. Fringe is a glycosyltransferase that modifies Notch. Nature 2000, 406(6794):369-375.
    • (2000) Nature , vol.406 , Issue.6794 , pp. 369-375
    • Moloney, D.J.1
  • 33
    • 0242593940 scopus 로고    scopus 로고
    • Glycosyltransferase activity of Fringe modulates Notch-Delta interactions
    • Bruckner K., et al. Glycosyltransferase activity of Fringe modulates Notch-Delta interactions. Nature 2000, 406(6794):411-415.
    • (2000) Nature , vol.406 , Issue.6794 , pp. 411-415
    • Bruckner, K.1
  • 34
    • 0032493302 scopus 로고    scopus 로고
    • The Notch1 receptor is cleaved constitutively by a furin-like convertase
    • Logeat F., et al. The Notch1 receptor is cleaved constitutively by a furin-like convertase. Proc. Natl. Acad. Sci. U. S. A. 1998, 95(14):8108-8112.
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , Issue.14 , pp. 8108-8112
    • Logeat, F.1
  • 35
    • 0028203495 scopus 로고
    • Sequence of C. elegans lag-2 reveals a cell-signalling domain shared with Delta and Serrate of Drosophila
    • Tax F.E., Yeargers J.J., Thomas J.H. Sequence of C. elegans lag-2 reveals a cell-signalling domain shared with Delta and Serrate of Drosophila. Nature 1994, 368(6467):150-154.
    • (1994) Nature , vol.368 , Issue.6467 , pp. 150-154
    • Tax, F.E.1    Yeargers, J.J.2    Thomas, J.H.3
  • 36
    • 0028950732 scopus 로고
    • Jagged: a mammalian ligand that activates Notch1
    • Lindsell C.E., et al. Jagged: a mammalian ligand that activates Notch1. Cell 1995, 80(6):909-917.
    • (1995) Cell , vol.80 , Issue.6 , pp. 909-917
    • Lindsell, C.E.1
  • 37
    • 50249096721 scopus 로고    scopus 로고
    • OSM-11 facilitates LIN-12 Notch signaling during Caenorhabditis elegans vulval development
    • Komatsu H., et al. OSM-11 facilitates LIN-12 Notch signaling during Caenorhabditis elegans vulval development. PLoS Biol. 2008, 6(8):e196.
    • (2008) PLoS Biol. , vol.6 , Issue.8
    • Komatsu, H.1
  • 38
    • 0038664363 scopus 로고    scopus 로고
    • Reconstitution of gamma-secretase activity
    • Edbauer D., et al. Reconstitution of gamma-secretase activity. Nat.Cell Biol. 2003, 5(5):486-488.
    • (2003) Nat.Cell Biol. , vol.5 , Issue.5 , pp. 486-488
    • Edbauer, D.1
  • 39
    • 18644367748 scopus 로고    scopus 로고
    • Presenilins mediate a dual intramembranous gamma-secretase cleavage of Notch-1
    • Okochi M., et al. Presenilins mediate a dual intramembranous gamma-secretase cleavage of Notch-1. EMBO J. 2002, 21(20):5408-5416.
    • (2002) EMBO J. , vol.21 , Issue.20 , pp. 5408-5416
    • Okochi, M.1
  • 40
    • 0032574993 scopus 로고    scopus 로고
    • Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain
    • Schroeter E.H., Kisslinger J.A., Kopan R. Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain. Nature 1998, 393(6683):382-386.
    • (1998) Nature , vol.393 , Issue.6683 , pp. 382-386
    • Schroeter, E.H.1    Kisslinger, J.A.2    Kopan, R.3
  • 41
    • 0032524325 scopus 로고    scopus 로고
    • Nuclear access and action of notch in vivo
    • Struhl G., Adachi A. Nuclear access and action of notch in vivo. Cell 1998, 93(4):649-660.
    • (1998) Cell , vol.93 , Issue.4 , pp. 649-660
    • Struhl, G.1    Adachi, A.2
  • 42
    • 0033867521 scopus 로고    scopus 로고
    • A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1
    • Mumm J.S., et al. A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1. Mol. Cell 2000, 5(2):197-206.
    • (2000) Mol. Cell , vol.5 , Issue.2 , pp. 197-206
    • Mumm, J.S.1
  • 43
    • 0035650895 scopus 로고    scopus 로고
    • Xenopus neuralized is a ubiquitin ligase that interacts with XDelta1 and regulates Notch signaling
    • Deblandre G.A., Lai E.C., Kintner C. Xenopus neuralized is a ubiquitin ligase that interacts with XDelta1 and regulates Notch signaling. Dev. Cell 2001, 1(6):795-806.
    • (2001) Dev. Cell , vol.1 , Issue.6 , pp. 795-806
    • Deblandre, G.A.1    Lai, E.C.2    Kintner, C.3
  • 44
    • 0035653308 scopus 로고    scopus 로고
    • Neuralized Encodes a peripheral membrane protein involved in delta signaling and endocytosis
    • Pavlopoulos E., et al. neuralized Encodes a peripheral membrane protein involved in delta signaling and endocytosis. Dev. Cell 2001, 1(6):807-816.
    • (2001) Dev. Cell , vol.1 , Issue.6 , pp. 807-816
    • Pavlopoulos, E.1
  • 45
    • 0037238008 scopus 로고    scopus 로고
    • Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta
    • Itoh M., et al. Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta. Dev. Cell 2003, 4(1):67-82.
    • (2003) Dev. Cell , vol.4 , Issue.1 , pp. 67-82
    • Itoh, M.1
  • 46
    • 0032552056 scopus 로고    scopus 로고
    • Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis
    • Chen H., et al. Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis. Nature 1998, 394(6695):793-797.
    • (1998) Nature , vol.394 , Issue.6695 , pp. 793-797
    • Chen, H.1
  • 47
    • 84862120880 scopus 로고    scopus 로고
    • Notch ligand endocytosis generates mechanical pulling force dependent on dynamin, epsins, and actin
    • Meloty-Kapella L., et al. Notch ligand endocytosis generates mechanical pulling force dependent on dynamin, epsins, and actin. Dev. Cell 2012, 22(6):1299-1312.
    • (2012) Dev. Cell , vol.22 , Issue.6 , pp. 1299-1312
    • Meloty-Kapella, L.1
  • 48
    • 0032145527 scopus 로고    scopus 로고
    • A histone deacetylase corepressor complex regulates the Notch signal transduction pathway
    • Kao H.Y., et al. A histone deacetylase corepressor complex regulates the Notch signal transduction pathway. Genes Dev. 1998, 12(15):2269-2277.
    • (1998) Genes Dev. , vol.12 , Issue.15 , pp. 2269-2277
    • Kao, H.Y.1
  • 49
    • 0033662392 scopus 로고    scopus 로고
    • MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors
    • Wu L., et al. MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors. Nat. Genet. 2000, 26(4):484-489.
    • (2000) Nat. Genet. , vol.26 , Issue.4 , pp. 484-489
    • Wu, L.1
  • 50
    • 0036606776 scopus 로고    scopus 로고
    • Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex
    • Fryer C.J., et al. Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex. Genes Dev. 2002, 16(11):1397-1411.
    • (2002) Genes Dev. , vol.16 , Issue.11 , pp. 1397-1411
    • Fryer, C.J.1
  • 51
    • 84869096429 scopus 로고    scopus 로고
    • NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function
    • Yatim A., et al. NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function. Mol. Cell 2012, 48(3):445-458.
    • (2012) Mol. Cell , vol.48 , Issue.3 , pp. 445-458
    • Yatim, A.1
  • 52
    • 16844366556 scopus 로고    scopus 로고
    • RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells
    • Robert-Moreno A., et al. RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells. Development 2005, 132(5):1117-1126.
    • (2005) Development , vol.132 , Issue.5 , pp. 1117-1126
    • Robert-Moreno, A.1
  • 53
    • 46949110648 scopus 로고    scopus 로고
    • Impaired embryonic haematopoiesis yet normal arterial development in the absence of the Notch ligand Jagged1
    • Robert-Moreno A., et al. Impaired embryonic haematopoiesis yet normal arterial development in the absence of the Notch ligand Jagged1. EMBO J. 2008, 27(13):1886-1895.
    • (2008) EMBO J. , vol.27 , Issue.13 , pp. 1886-1895
    • Robert-Moreno, A.1
  • 54
    • 1942498907 scopus 로고    scopus 로고
    • The Notch target genes Hey1 and Hey2 are required for embryonic vascular development
    • Fischer A., et al. The Notch target genes Hey1 and Hey2 are required for embryonic vascular development. Genes Dev. 2004, 18(8):901-911.
    • (2004) Genes Dev. , vol.18 , Issue.8 , pp. 901-911
    • Fischer, A.1
  • 55
    • 84874508773 scopus 로고    scopus 로고
    • Hes repressors are essential regulators of hematopoietic stem cell development downstream of Notch signaling
    • Guiu J., et al. Hes repressors are essential regulators of hematopoietic stem cell development downstream of Notch signaling. J. Exp. Med. 2013, 210(1):71-84.
    • (2013) J. Exp. Med. , vol.210 , Issue.1 , pp. 71-84
    • Guiu, J.1
  • 56
    • 0033564756 scopus 로고    scopus 로고
    • The mouse GATA-2 gene is expressed in the para-aortic splanchnopleura and aorta-gonads and mesonephros region
    • Minegishi N., et al. The mouse GATA-2 gene is expressed in the para-aortic splanchnopleura and aorta-gonads and mesonephros region. Blood 1999, 93(12):4196-4207.
    • (1999) Blood , vol.93 , Issue.12 , pp. 4196-4207
    • Minegishi, N.1
  • 57
    • 34249037850 scopus 로고    scopus 로고
    • A Gata2 intronic enhancer confers its pan-endothelia-specific regulation
    • Khandekar M., et al. A Gata2 intronic enhancer confers its pan-endothelia-specific regulation. Development 2007, 134(9):1703-1712.
    • (2007) Development , vol.134 , Issue.9 , pp. 1703-1712
    • Khandekar, M.1
  • 58
    • 0034212710 scopus 로고    scopus 로고
    • Notch signaling is essential for vascular morphogenesis in mice
    • Krebs L.T., et al. Notch signaling is essential for vascular morphogenesis in mice. Genes Dev. 2000, 14(11):1343-1352.
    • (2000) Genes Dev. , vol.14 , Issue.11 , pp. 1343-1352
    • Krebs, L.T.1
  • 59
    • 5444242184 scopus 로고    scopus 로고
    • Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants
    • Krebs L.T., et al. Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants. Genes Dev. 2004, 18(20):2469-2473.
    • (2004) Genes Dev. , vol.18 , Issue.20 , pp. 2469-2473
    • Krebs, L.T.1
  • 60
    • 0034195220 scopus 로고    scopus 로고
    • Dll4, a novel Notch ligand expressed in arterial endothelium
    • Shutter J.R., et al. Dll4, a novel Notch ligand expressed in arterial endothelium. Genes Dev. 2000, 14(11):1313-1318.
    • (2000) Genes Dev. , vol.14 , Issue.11 , pp. 1313-1318
    • Shutter, J.R.1
  • 61
    • 5444261424 scopus 로고    scopus 로고
    • Dosage-sensitive requirement for mouse Dll4 in artery development
    • Duarte A., et al. Dosage-sensitive requirement for mouse Dll4 in artery development. Genes Dev. 2004, 18(20):2474-2478.
    • (2004) Genes Dev. , vol.18 , Issue.20 , pp. 2474-2478
    • Duarte, A.1
  • 62
    • 0038404519 scopus 로고    scopus 로고
    • Notch1 but not Notch2 is essential for generating hematopoietic stem cells from endothelial cells
    • Kumano K., et al. Notch1 but not Notch2 is essential for generating hematopoietic stem cells from endothelial cells. Immunity 2003, 18(5):699-711.
    • (2003) Immunity , vol.18 , Issue.5 , pp. 699-711
    • Kumano, K.1
  • 63
    • 25844493155 scopus 로고    scopus 로고
    • Hematopoietic stem cell fate is established by the Notch-Runx pathway
    • Burns C.E., et al. Hematopoietic stem cell fate is established by the Notch-Runx pathway. Genes Dev. 2005, 19(19):2331-2342.
    • (2005) Genes Dev. , vol.19 , Issue.19 , pp. 2331-2342
    • Burns, C.E.1
  • 64
    • 65549102186 scopus 로고    scopus 로고
    • Hematopoietic stem cell development is dependent on blood flow
    • North T.E., et al. Hematopoietic stem cell development is dependent on blood flow. Cell 2009, 137(4):736-748.
    • (2009) Cell , vol.137 , Issue.4 , pp. 736-748
    • North, T.E.1
  • 65
    • 0033757655 scopus 로고    scopus 로고
    • Arteriovenous malformations in mice lacking activin receptor-like kinase-1
    • Urness L.D., Sorensen L.K., Li D.Y. Arteriovenous malformations in mice lacking activin receptor-like kinase-1. Nat. Genet. 2000, 26(3):328-331.
    • (2000) Nat. Genet. , vol.26 , Issue.3 , pp. 328-331
    • Urness, L.D.1    Sorensen, L.K.2    Li, D.Y.3
  • 66
    • 0043164827 scopus 로고    scopus 로고
    • Loss of distinct arterial and venous boundaries in mice lacking endoglin, a vascular-specific TGFbeta coreceptor
    • Sorensen L.K., et al. Loss of distinct arterial and venous boundaries in mice lacking endoglin, a vascular-specific TGFbeta coreceptor. Dev. Biol. 2003, 261(1):235-250.
    • (2003) Dev. Biol. , vol.261 , Issue.1 , pp. 235-250
    • Sorensen, L.K.1
  • 67
    • 18344377007 scopus 로고    scopus 로고
    • Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity
    • You L.R., et al. Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity. Nature 2005, 435(7038):98-104.
    • (2005) Nature , vol.435 , Issue.7038 , pp. 98-104
    • You, L.R.1
  • 68
    • 67049108093 scopus 로고    scopus 로고
    • DLL1-mediated Notch activation regulates endothelial identity in mouse fetal arteries
    • Sorensen I., Adams R.H., Gossler A. DLL1-mediated Notch activation regulates endothelial identity in mouse fetal arteries. Blood 2009, 113(22):5680-5688.
    • (2009) Blood , vol.113 , Issue.22 , pp. 5680-5688
    • Sorensen, I.1    Adams, R.H.2    Gossler, A.3
  • 69
    • 0032897080 scopus 로고    scopus 로고
    • Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1
    • Xue Y., et al. Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1. Hum. Mol. Genet. 1999, 8(5):723-730.
    • (1999) Hum. Mol. Genet. , vol.8 , Issue.5 , pp. 723-730
    • Xue, Y.1
  • 70
    • 41149156903 scopus 로고    scopus 로고
    • Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development
    • High F.A., et al. Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development. Proc. Natl. Acad. Sci. U. S. A. 2008, 105(6):1955-1959.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , Issue.6 , pp. 1955-1959
    • High, F.A.1
  • 71
    • 0028971681 scopus 로고
    • Disruption of the mouse RBP-J kappa gene results in early embryonic death
    • Oka C., et al. Disruption of the mouse RBP-J kappa gene results in early embryonic death. Development 1995, 121(10):3291-3301.
    • (1995) Development , vol.121 , Issue.10 , pp. 3291-3301
    • Oka, C.1
  • 72
    • 0037547158 scopus 로고    scopus 로고
    • Protein O-fucosyltransferase 1 is an essential component of Notch signaling pathways
    • Shi S., Stanley P. Protein O-fucosyltransferase 1 is an essential component of Notch signaling pathways. Proc. Natl. Acad. Sci. U. S. A. 2003, 100(9):5234-5239.
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , Issue.9 , pp. 5234-5239
    • Shi, S.1    Stanley, P.2
  • 73
    • 0032728957 scopus 로고    scopus 로고
    • Mice lacking both presenilin genes exhibit early embryonic patterning defects
    • Donoviel D.B., et al. Mice lacking both presenilin genes exhibit early embryonic patterning defects. Genes Dev. 1999, 13(21):2801-2810.
    • (1999) Genes Dev. , vol.13 , Issue.21 , pp. 2801-2810
    • Donoviel, D.B.1
  • 74
    • 0345689442 scopus 로고    scopus 로고
    • Characterization of Notch3-deficient mice: normal embryonic development and absence of genetic interactions with a Notch1 mutation
    • Krebs L.T., et al. Characterization of Notch3-deficient mice: normal embryonic development and absence of genetic interactions with a Notch1 mutation. Genesis 2003, 37(3):139-143.
    • (2003) Genesis , vol.37 , Issue.3 , pp. 139-143
    • Krebs, L.T.1
  • 75
    • 0032054238 scopus 로고    scopus 로고
    • Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice
    • Jiang R., et al. Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice. Genes Dev. 1998, 12(7):1046-1057.
    • (1998) Genes Dev. , vol.12 , Issue.7 , pp. 1046-1057
    • Jiang, R.1
  • 76
    • 84873094555 scopus 로고    scopus 로고
    • Uncoupling VEGFA functions in arteriogenesis and hematopoietic stem cell specification
    • Leung A., et al. Uncoupling VEGFA functions in arteriogenesis and hematopoietic stem cell specification. Dev. Cell 2013, 24(2):144-158.
    • (2013) Dev. Cell , vol.24 , Issue.2 , pp. 144-158
    • Leung, A.1
  • 77
    • 33751163726 scopus 로고    scopus 로고
    • AML1/Runx1 rescues Notch1-null mutation-induced deficiency of para-aortic splanchnopleural hematopoiesis
    • Nakagawa M., et al. AML1/Runx1 rescues Notch1-null mutation-induced deficiency of para-aortic splanchnopleural hematopoiesis. Blood 2006, 108(10):3329-3334.
    • (2006) Blood , vol.108 , Issue.10 , pp. 3329-3334
    • Nakagawa, M.1
  • 78
    • 79958290042 scopus 로고    scopus 로고
    • A somitic Wnt16/Notch pathway specifies haematopoietic stem cells
    • Clements W.K., et al. A somitic Wnt16/Notch pathway specifies haematopoietic stem cells. Nature 2011, 474(7350):220-224.
    • (2011) Nature , vol.474 , Issue.7350 , pp. 220-224
    • Clements, W.K.1
  • 79
    • 33845892748 scopus 로고    scopus 로고
    • Jagged 1 is a beta-catenin target gene required for ectopic hair follicle formation in adult epidermis
    • Estrach S., et al. Jagged 1 is a beta-catenin target gene required for ectopic hair follicle formation in adult epidermis. Development 2006, 133(22):4427-4438.
    • (2006) Development , vol.133 , Issue.22 , pp. 4427-4438
    • Estrach, S.1
  • 80
    • 65549140672 scopus 로고    scopus 로고
    • Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer
    • Rodilla V., et al. Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer. Proc. Natl. Acad. Sci. U. S. A. 2009, 106(15):6315-6320.
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , Issue.15 , pp. 6315-6320
    • Rodilla, V.1
  • 81
    • 77955977167 scopus 로고    scopus 로고
    • The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling
    • Corada M., et al. The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling. Dev. Cell 2010, 18(6):938-949.
    • (2010) Dev. Cell , vol.18 , Issue.6 , pp. 938-949
    • Corada, M.1
  • 82
    • 67649470380 scopus 로고    scopus 로고
    • Proximal events in Wnt signal transduction
    • Angers S., Moon R.T. Proximal events in Wnt signal transduction. Nat. Rev. Mol. Cell Biol. 2009, 10(7):468-477.
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , Issue.7 , pp. 468-477
    • Angers, S.1    Moon, R.T.2
  • 83
    • 0037737726 scopus 로고    scopus 로고
    • Wnt proteins are lipid-modified and can act as stem cell growth factors
    • Willert K., et al. Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature 2003, 423(6938):448-452.
    • (2003) Nature , vol.423 , Issue.6938 , pp. 448-452
    • Willert, K.1
  • 84
    • 0033616573 scopus 로고    scopus 로고
    • Biochemical characterization of Wnt-frizzled interactions using a soluble, biologically active vertebrate Wnt protein
    • Hsieh J.C., et al. Biochemical characterization of Wnt-frizzled interactions using a soluble, biologically active vertebrate Wnt protein. Proc. Natl. Acad. Sci. U. S. A. 1999, 96(7):3546-3551.
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , Issue.7 , pp. 3546-3551
    • Hsieh, J.C.1
  • 85
    • 0034727104 scopus 로고    scopus 로고
    • LDL-receptor-related proteins in Wnt signal transduction
    • Tamai K., et al. LDL-receptor-related proteins in Wnt signal transduction. Nature 2000, 407(6803):530-535.
    • (2000) Nature , vol.407 , Issue.6803 , pp. 530-535
    • Tamai, K.1
  • 86
    • 0029664368 scopus 로고    scopus 로고
    • Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly
    • Rubinfeld B., et al. Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly. Science 1996, 272(5264):1023-1026.
    • (1996) Science , vol.272 , Issue.5264 , pp. 1023-1026
    • Rubinfeld, B.1
  • 87
    • 0030800831 scopus 로고    scopus 로고
    • Three-dimensional structure of the armadillo repeat region of beta-catenin
    • Huber A.H., Nelson W.J., Weis W.I. Three-dimensional structure of the armadillo repeat region of beta-catenin. Cell 1997, 90(5):871-882.
    • (1997) Cell , vol.90 , Issue.5 , pp. 871-882
    • Huber, A.H.1    Nelson, W.J.2    Weis, W.I.3
  • 88
    • 0028069007 scopus 로고
    • Tumor-suppressor gene products in cell contacts: the cadherin-APC-armadillo connection
    • Hulsken J., Behrens J., Birchmeier W. Tumor-suppressor gene products in cell contacts: the cadherin-APC-armadillo connection. Curr. Opin. Cell Biol. 1994, 6(5):711-716.
    • (1994) Curr. Opin. Cell Biol. , vol.6 , Issue.5 , pp. 711-716
    • Hulsken, J.1    Behrens, J.2    Birchmeier, W.3
  • 89
    • 0032562603 scopus 로고    scopus 로고
    • Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta
    • Behrens J., et al. Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta. Science 1998, 280(5363):596-599.
    • (1998) Science , vol.280 , Issue.5363 , pp. 596-599
    • Behrens, J.1
  • 90
    • 0033635606 scopus 로고    scopus 로고
    • Crystal structure of a beta-catenin/Tcf complex
    • Graham T.A., et al. Crystal structure of a beta-catenin/Tcf complex. Cell 2000, 103(6):885-896.
    • (2000) Cell , vol.103 , Issue.6 , pp. 885-896
    • Graham, T.A.1
  • 91
    • 0026661360 scopus 로고
    • The vertebrate adhesive junction proteins beta-catenin and plakoglobin and the Drosophila segment polarity gene armadillo form a multigene family with similar properties
    • Peifer M., et al. The vertebrate adhesive junction proteins beta-catenin and plakoglobin and the Drosophila segment polarity gene armadillo form a multigene family with similar properties. J. Cell Biol. 1992, 118(3):681-691.
    • (1992) J. Cell Biol. , vol.118 , Issue.3 , pp. 681-691
    • Peifer, M.1
  • 92
    • 0028572556 scopus 로고
    • E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton
    • Hulsken J., Birchmeier W., Behrens J. E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton. J. Cell Biol. 1994, 127(6 Pt 2):2061-2069.
    • (1994) J. Cell Biol. , vol.127 , Issue.6 PART 2 , pp. 2061-2069
    • Hulsken, J.1    Birchmeier, W.2    Behrens, J.3
  • 93
    • 0030978351 scopus 로고    scopus 로고
    • Beta-catenin is a target for the ubiquitin-proteasome pathway
    • Aberle H., et al. beta-catenin is a target for the ubiquitin-proteasome pathway. EMBO J. 1997, 16(13):3797-3804.
    • (1997) EMBO J. , vol.16 , Issue.13 , pp. 3797-3804
    • Aberle, H.1
  • 94
    • 0037022275 scopus 로고    scopus 로고
    • Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex
    • Gao Z.H., et al. Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex. Proc. Natl. Acad. Sci. U. S. A. 2002, 99(3):1182-1187.
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , Issue.3 , pp. 1182-1187
    • Gao, Z.H.1
  • 95
    • 0036571011 scopus 로고    scopus 로고
    • Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway
    • Amit S., et al. Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway. Genes Dev. 2002, 16(9):1066-1076.
    • (2002) Genes Dev. , vol.16 , Issue.9 , pp. 1066-1076
    • Amit, S.1
  • 96
    • 0037155691 scopus 로고    scopus 로고
    • Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism
    • Liu C., et al. Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism. Cell 2002, 108(6):837-847.
    • (2002) Cell , vol.108 , Issue.6 , pp. 837-847
    • Liu, C.1
  • 97
    • 0029994517 scopus 로고    scopus 로고
    • A new member of the frizzled family from Drosophila functions as a Wingless receptor
    • Bhanot P., et al. A new member of the frizzled family from Drosophila functions as a Wingless receptor. Nature 1996, 382(6588):225-230.
    • (1996) Nature , vol.382 , Issue.6588 , pp. 225-230
    • Bhanot, P.1
  • 98
    • 0033714885 scopus 로고    scopus 로고
    • Control of beta-catenin stability: reconstitution of the cytoplasmic steps of the wnt pathway in Xenopus egg extracts
    • Salic A., et al. Control of beta-catenin stability: reconstitution of the cytoplasmic steps of the wnt pathway in Xenopus egg extracts. Mol. Cell 2000, 5(3):523-532.
    • (2000) Mol. Cell , vol.5 , Issue.3 , pp. 523-532
    • Salic, A.1
  • 99
    • 0029781509 scopus 로고    scopus 로고
    • Functional interaction of beta-catenin with the transcription factor LEF-1
    • Behrens J., et al. Functional interaction of beta-catenin with the transcription factor LEF-1. Nature 1996, 382(6592):638-642.
    • (1996) Nature , vol.382 , Issue.6592 , pp. 638-642
    • Behrens, J.1
  • 100
    • 0001003110 scopus 로고    scopus 로고
    • XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos
    • Molenaar M., et al. XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos. Cell 1996, 86(3):391-399.
    • (1996) Cell , vol.86 , Issue.3 , pp. 391-399
    • Molenaar, M.1
  • 101
    • 0030999806 scopus 로고    scopus 로고
    • Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF
    • van de Wetering M., et al. Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF. Cell 1997, 88(6):789-799.
    • (1997) Cell , vol.88 , Issue.6 , pp. 789-799
    • van de Wetering, M.1
  • 102
    • 0036148208 scopus 로고    scopus 로고
    • Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway
    • Jho E.H., et al. Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway. Mol. Cell. Biol. 2002, 22(4):1172-1183.
    • (2002) Mol. Cell. Biol. , vol.22 , Issue.4 , pp. 1172-1183
    • Jho, E.H.1
  • 103
    • 0037043688 scopus 로고    scopus 로고
    • Wnt-11 activation of a non-canonical Wnt signalling pathway is required for cardiogenesis
    • Pandur P., et al. Wnt-11 activation of a non-canonical Wnt signalling pathway is required for cardiogenesis. Nature 2002, 418(6898):636-641.
    • (2002) Nature , vol.418 , Issue.6898 , pp. 636-641
    • Pandur, P.1
  • 104
    • 0043234810 scopus 로고    scopus 로고
    • Wnt-5/pipetail functions in vertebrate axis formation as a negative regulator of Wnt/beta-catenin activity
    • Westfall T.A., et al. Wnt-5/pipetail functions in vertebrate axis formation as a negative regulator of Wnt/beta-catenin activity. J. Cell Biol. 2003, 162(5):889-898.
    • (2003) J. Cell Biol. , vol.162 , Issue.5 , pp. 889-898
    • Westfall, T.A.1
  • 105
    • 80053466165 scopus 로고    scopus 로고
    • Wnt/Ca2+ signaling pathway: a brief overview
    • De A. Wnt/Ca2+ signaling pathway: a brief overview. Acta Biochim. Biophys. Sin. 2011, 43(10):745-756.
    • (2011) Acta Biochim. Biophys. Sin. , vol.43 , Issue.10 , pp. 745-756
    • De, A.1
  • 106
    • 21244479003 scopus 로고    scopus 로고
    • Essential role of non-canonical Wnt signalling in neural crest migration
    • De Calisto J., et al. Essential role of non-canonical Wnt signalling in neural crest migration. Development 2005, 132(11):2587-2597.
    • (2005) Development , vol.132 , Issue.11 , pp. 2587-2597
    • De Calisto, J.1
  • 107
    • 77951888466 scopus 로고    scopus 로고
    • Dishevelled: The hub of Wnt signaling
    • Gao C., Chen Y.G. Dishevelled: The hub of Wnt signaling. Cell. Signal. 2010, 22(5):717-727.
    • (2010) Cell. Signal. , vol.22 , Issue.5 , pp. 717-727
    • Gao, C.1    Chen, Y.G.2
  • 108
    • 0142042539 scopus 로고    scopus 로고
    • Frizzled signalling and cell polarisation in Drosophila and vertebrates
    • Strutt D. Frizzled signalling and cell polarisation in Drosophila and vertebrates. Development 2003, 130(19):4501-4513.
    • (2003) Development , vol.130 , Issue.19 , pp. 4501-4513
    • Strutt, D.1
  • 109
    • 0041695485 scopus 로고    scopus 로고
    • A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling
    • Veeman M.T., Axelrod J.D., Moon R.T. A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling. Dev. Cell 2003, 5(3):367-377.
    • (2003) Dev. Cell , vol.5 , Issue.3 , pp. 367-377
    • Veeman, M.T.1    Axelrod, J.D.2    Moon, R.T.3
  • 110
    • 84866443757 scopus 로고    scopus 로고
    • Hematopoietic stem cell development requires transient Wnt/beta-catenin activity
    • Ruiz-Herguido C., et al. Hematopoietic stem cell development requires transient Wnt/beta-catenin activity. J. Exp. Med. 2012, 209(8):1457-1468.
    • (2012) J. Exp. Med. , vol.209 , Issue.8 , pp. 1457-1468
    • Ruiz-Herguido, C.1
  • 111
    • 66249120015 scopus 로고    scopus 로고
    • Patterns of Wnt/Fzd/LRP gene expression during embryonic hematopoiesis
    • Corrigan P.M., et al. Patterns of Wnt/Fzd/LRP gene expression during embryonic hematopoiesis. Stem Cells Dev. 2009, 18(5):759-772.
    • (2009) Stem Cells Dev. , vol.18 , Issue.5 , pp. 759-772
    • Corrigan, P.M.1
  • 112
    • 33750973380 scopus 로고    scopus 로고
    • Cultured endothelial cells display endogenous activation of the canonical Wnt signaling pathway and express multiple ligands, receptors, and secreted modulators of Wnt signaling
    • Goodwin A.M., Sullivan K.M., D'Amore P.A. Cultured endothelial cells display endogenous activation of the canonical Wnt signaling pathway and express multiple ligands, receptors, and secreted modulators of Wnt signaling. Dev. Dyn. 2006, 235(11):3110-3120.
    • (2006) Dev. Dyn. , vol.235 , Issue.11 , pp. 3110-3120
    • Goodwin, A.M.1    Sullivan, K.M.2    D'Amore, P.A.3
  • 113
    • 70350126572 scopus 로고    scopus 로고
    • Microwell-mediated control of embryoid body size regulates embryonic stem cell fate via differential expression of WNT5a and WNT11
    • Hwang Y.S., et al. Microwell-mediated control of embryoid body size regulates embryonic stem cell fate via differential expression of WNT5a and WNT11. Proc. Natl. Acad. Sci. U. S. A. 2009, 106(40):16978-16983.
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , Issue.40 , pp. 16978-16983
    • Hwang, Y.S.1
  • 114
    • 0141768242 scopus 로고    scopus 로고
    • The conditional inactivation of the beta-catenin gene in endothelial cells causes a defective vascular pattern and increased vascular fragility
    • Cattelino A., et al. The conditional inactivation of the beta-catenin gene in endothelial cells causes a defective vascular pattern and increased vascular fragility. J. Cell Biol. 2003, 162(6):1111-1122.
    • (2003) J. Cell Biol. , vol.162 , Issue.6 , pp. 1111-1122
    • Cattelino, A.1
  • 115
    • 0029911964 scopus 로고    scopus 로고
    • Targeted disruption of the Wnt2 gene results in placentation defects
    • Monkley S.J., et al. Targeted disruption of the Wnt2 gene results in placentation defects. Development 1996, 122(11):3343-3353.
    • (1996) Development , vol.122 , Issue.11 , pp. 3343-3353
    • Monkley, S.J.1
  • 116
    • 0035155579 scopus 로고    scopus 로고
    • Mouse Wnt receptor gene Fzd5 is essential for yolk sac and placental angiogenesis
    • Ishikawa T., et al. Mouse Wnt receptor gene Fzd5 is essential for yolk sac and placental angiogenesis. Development 2001, 128(1):25-33.
    • (2001) Development , vol.128 , Issue.1 , pp. 25-33
    • Ishikawa, T.1
  • 117
    • 77951197865 scopus 로고    scopus 로고
    • Convergence of Notch and beta-catenin signaling induces arterial fate in vascular progenitors
    • Yamamizu K., et al. Convergence of Notch and beta-catenin signaling induces arterial fate in vascular progenitors. J. Cell Biol. 2010, 189(2):325-338.
    • (2010) J. Cell Biol. , vol.189 , Issue.2 , pp. 325-338
    • Yamamizu, K.1
  • 118
    • 0035899466 scopus 로고    scopus 로고
    • IGF-II induces rapid beta-catenin relocation to the nucleus during epithelium to mesenchyme transition
    • Morali O.G., et al. IGF-II induces rapid beta-catenin relocation to the nucleus during epithelium to mesenchyme transition. Oncogene 2001, 20(36):4942-4950.
    • (2001) Oncogene , vol.20 , Issue.36 , pp. 4942-4950
    • Morali, O.G.1
  • 119
    • 77949911441 scopus 로고    scopus 로고
    • In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium
    • Boisset J.C., et al. In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium. Nature 2010, 464(7285):116-120.
    • (2010) Nature , vol.464 , Issue.7285 , pp. 116-120
    • Boisset, J.C.1
  • 120
    • 77949895151 scopus 로고    scopus 로고
    • Haematopoietic stem cells derive directly from aortic endothelium during development
    • Bertrand J.Y., et al. Haematopoietic stem cells derive directly from aortic endothelium during development. Nature 2010, 464(7285):108-111.
    • (2010) Nature , vol.464 , Issue.7285 , pp. 108-111
    • Bertrand, J.Y.1
  • 121
    • 62149148156 scopus 로고    scopus 로고
    • Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration
    • Goessling W., et al. Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration. Cell 2009, 136(6):1136-1147.
    • (2009) Cell , vol.136 , Issue.6 , pp. 1136-1147
    • Goessling, W.1
  • 122
    • 60249101799 scopus 로고    scopus 로고
    • Wnt3a deficiency irreversibly impairs hematopoietic stem cell self-renewal and leads to defects in progenitor cell differentiation
    • Luis T.C., et al. Wnt3a deficiency irreversibly impairs hematopoietic stem cell self-renewal and leads to defects in progenitor cell differentiation. Blood 2009, 113(3):546-554.
    • (2009) Blood , vol.113 , Issue.3 , pp. 546-554
    • Luis, T.C.1
  • 123
    • 36649002031 scopus 로고    scopus 로고
    • Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivo
    • Zhao C., et al. Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivo. Cancer Cell 2007, 12(6):528-541.
    • (2007) Cancer Cell , vol.12 , Issue.6 , pp. 528-541
    • Zhao, C.1
  • 124
    • 38049105637 scopus 로고    scopus 로고
    • Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin
    • Jeannet G., et al. Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin. Blood 2008, 111(1):142-149.
    • (2008) Blood , vol.111 , Issue.1 , pp. 142-149
    • Jeannet, G.1
  • 125
    • 1642499734 scopus 로고    scopus 로고
    • Beta-catenin is dispensable for hematopoiesis and lymphopoiesis
    • Cobas M., et al. Beta-catenin is dispensable for hematopoiesis and lymphopoiesis. J. Exp. Med. 2004, 199(2):221-229.
    • (2004) J. Exp. Med. , vol.199 , Issue.2 , pp. 221-229
    • Cobas, M.1
  • 126
    • 38049139201 scopus 로고    scopus 로고
    • Simultaneous loss of beta- and gamma-catenin does not perturb hematopoiesis or lymphopoiesis
    • Koch U., et al. Simultaneous loss of beta- and gamma-catenin does not perturb hematopoiesis or lymphopoiesis. Blood 2008, 111(1):160-164.
    • (2008) Blood , vol.111 , Issue.1 , pp. 160-164
    • Koch, U.1
  • 127
    • 0037737728 scopus 로고    scopus 로고
    • A role for Wnt signalling in self-renewal of haematopoietic stem cells
    • Reya T., et al. A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature 2003, 423(6938):409-414.
    • (2003) Nature , vol.423 , Issue.6938 , pp. 409-414
    • Reya, T.1
  • 128
    • 28844455024 scopus 로고    scopus 로고
    • Constitutively active beta-catenin confers multilineage differentiation potential on lymphoid and myeloid progenitors
    • Baba Y., Garrett K.P., Kincade P.W. Constitutively active beta-catenin confers multilineage differentiation potential on lymphoid and myeloid progenitors. Immunity 2005, 23(6):599-609.
    • (2005) Immunity , vol.23 , Issue.6 , pp. 599-609
    • Baba, Y.1    Garrett, K.P.2    Kincade, P.W.3
  • 129
    • 33748850636 scopus 로고    scopus 로고
    • Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block
    • Kirstetter P., et al. Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block. Nat. Immunol. 2006, 7(10):1048-1056.
    • (2006) Nat. Immunol. , vol.7 , Issue.10 , pp. 1048-1056
    • Kirstetter, P.1
  • 130
    • 33748859509 scopus 로고    scopus 로고
    • Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation
    • Scheller M., et al. Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation. Nat. Immunol. 2006, 7(10):1037-1047.
    • (2006) Nat. Immunol. , vol.7 , Issue.10 , pp. 1037-1047
    • Scheller, M.1
  • 131
    • 80053907201 scopus 로고    scopus 로고
    • Canonical wnt signaling regulates hematopoiesis in a dosage-dependent fashion
    • Luis T.C., et al. Canonical wnt signaling regulates hematopoiesis in a dosage-dependent fashion. Cell Stem Cell 2011, 9(4):345-356.
    • (2011) Cell Stem Cell , vol.9 , Issue.4 , pp. 345-356
    • Luis, T.C.1
  • 132
    • 84870866912 scopus 로고    scopus 로고
    • Maintenance of hematopoietic stem cells through regulation of Wnt and mTOR pathways
    • Huang J., et al. Maintenance of hematopoietic stem cells through regulation of Wnt and mTOR pathways. Nat. Med. 2012, 18(12):1778-1785.
    • (2012) Nat. Med. , vol.18 , Issue.12 , pp. 1778-1785
    • Huang, J.1
  • 133
    • 22344436360 scopus 로고    scopus 로고
    • P21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation
    • Devgan V., et al. p21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation. Genes Dev. 2005, 19(12):1485-1495.
    • (2005) Genes Dev. , vol.19 , Issue.12 , pp. 1485-1495
    • Devgan, V.1
  • 134
    • 0036332950 scopus 로고    scopus 로고
    • Axial skeletal defects caused by mutation in the spondylocostal dysplasia/pudgy gene Dll3 are associated with disruption of the segmentation clock within the presomitic mesoderm
    • Dunwoodie S.L., et al. Axial skeletal defects caused by mutation in the spondylocostal dysplasia/pudgy gene Dll3 are associated with disruption of the segmentation clock within the presomitic mesoderm. Development 2002, 129(7):1795-1806.
    • (2002) Development , vol.129 , Issue.7 , pp. 1795-1806
    • Dunwoodie, S.L.1
  • 135
    • 50649085986 scopus 로고    scopus 로고
    • Hes genes and neurogenin regulate non-neural versus neural fate specification in the dorsal telencephalic midline
    • Imayoshi I., et al. Hes genes and neurogenin regulate non-neural versus neural fate specification in the dorsal telencephalic midline. Development 2008, 135(15):2531-2541.
    • (2008) Development , vol.135 , Issue.15 , pp. 2531-2541
    • Imayoshi, I.1
  • 136
    • 5444223724 scopus 로고    scopus 로고
    • GATA-2 plays two functionally distinct roles during the ontogeny of hematopoietic stem cells
    • Ling K.W., et al. GATA-2 plays two functionally distinct roles during the ontogeny of hematopoietic stem cells. J. Exp. Med. 2004, 200(7):871-882.
    • (2004) J. Exp. Med. , vol.200 , Issue.7 , pp. 871-882
    • Ling, K.W.1
  • 137
    • 0028022916 scopus 로고
    • An early haematopoietic defect in mice lacking the transcription factor GATA-2
    • Tsai F.Y., et al. An early haematopoietic defect in mice lacking the transcription factor GATA-2. Nature 1994, 371(6494):221-226.
    • (1994) Nature , vol.371 , Issue.6494 , pp. 221-226
    • Tsai, F.Y.1
  • 138
    • 78649881432 scopus 로고    scopus 로고
    • When whorls collide: the development of hair patterns in frizzled 6 mutant mice
    • Wang Y., Chang H., Nathans J. When whorls collide: the development of hair patterns in frizzled 6 mutant mice. Development 2010, 137(23):4091-4099.
    • (2010) Development , vol.137 , Issue.23 , pp. 4091-4099
    • Wang, Y.1    Chang, H.2    Nathans, J.3
  • 139
    • 79953215305 scopus 로고    scopus 로고
    • T-cell factor 4 functions as a tumor suppressor whose disruption modulates colon cell proliferation and tumorigenesis
    • Angus-Hill M.L., et al. T-cell factor 4 functions as a tumor suppressor whose disruption modulates colon cell proliferation and tumorigenesis. Proc. Natl. Acad. Sci. U. S. A. 2011, (12):4914-4919.
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , Issue.12 , pp. 4914-4919
    • Angus-Hill, M.L.1
  • 140
    • 0034614937 scopus 로고    scopus 로고
    • Requirement for beta-catenin in anterior-posterior axis formation in mice
    • Huelsken J., et al. Requirement for beta-catenin in anterior-posterior axis formation in mice. J. Cell Biol. 2000, 148(3):567-578.
    • (2000) J. Cell Biol. , vol.148 , Issue.3 , pp. 567-578
    • Huelsken, J.1
  • 141
    • 0028971954 scopus 로고
    • Lack of beta-catenin affects mouse development at gastrulation
    • Haegel H., et al. Lack of beta-catenin affects mouse development at gastrulation. Development 1995, 121(11):3529-3537.
    • (1995) Development , vol.121 , Issue.11 , pp. 3529-3537
    • Haegel, H.1


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