The Abruptex domain of Notch regulates negative interactions between Notch, its ligands and Fringe

Development

Volumn 127, Issue 6, 2000, Pages 1291-1302

  De Celis, Jose F ^a   Bray, Sarah J ^b  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Abruptex; fringe; Notch signalling; Wing development

Indexed keywords

LIGAND; MEMBRANE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEVELOPMENTAL GENETICS; DROSOPHILA; EMBRYO; EMBRYO DEVELOPMENT; IMAGINAL DISC; MISSENSE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ANIMALS; DROSOPHILA; DROSOPHILA PROTEINS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, INSECT; GENETIC COMPLEMENTATION TEST; INSECT PROTEINS; LIGANDS; MALE; MEMBRANE PROTEINS; MUTATION, MISSENSE; N-ACETYLGLUCOSAMINYLTRANSFERASES; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; WING;

ANIMALIA; HEXAPODA; INVERTEBRATA; VERTEBRATA;

EID: 0034038237     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (71)

1. Artavanis-Tsakonas, S., Matsuno, K. and Fortini, M. E. (1995). Notch signalling. Science 268, 225-232.
2. ArtavanisTsakonas, S., Rand, M. D. and Lake, R. J. (1999). Notch signaling: Cell fate control and signal integration in development. Science 5415, 770-776.
3. Bailey, A. M. and Posakony, J. W. (1995). Suppressor of Hairless directly activates transription of Enhancer of split complex genes in response to Notch receptor activity. Genes Dev. 9, 2609-2622.
4. Baker, N. E. (1988). Transcription of the segment-polarity gene wingless in the imaginal discs of Drosophila, and the phenotype of a pupal-lethal wg mutant. Development 102, 489-497.
5. Blair, S. S. (1995). Compartments and appendage development in Drosophila. BioEssays 4, 299-309.
6. Blair, S. S., Brower, D. L., Thomas, J. B. and Zabortink, M. (1994). The role of apterous in the control of dorsoventral compartmentalization and PS integrin gene expression in the developing wing of Drosophila. Development 120, 1805-1815.
7. Blochinger, K., Bodmer, R., Jan, L. Y. and Jan, Y. N. (1990). Patterns of expression of Cut, a protein required for external sensory organ development in wild-type and cut mutant Drosophila embryos. Genes Dev. 4, 1322-1331.
8. Blochinger, K., Jan, L. Y. and Jan, Y. N. (1993). Postembryonic patterns of expression of cut, a locus regulating sensory organ identity in Drosophila. Development 117, 441-450.
9. Cho, K.-O. and Choi, K.-W. (1998). Fringe is essential for mirror symmetry and morphogenesis in the Drosophila eye. Nature 396, 272-276:
10. Cohen, B., McGuffin, M. E., Pfeifle, C., Segal, D. and Cohen, S. M. (1992). apterous, a gene required for imaginal disc development in Drosophila encodes a menber of the LIM family of developmental regulatory proteins. Genes Dev. 6, 715-729.
11. Couso, J. P., Knust, E. and Martinez Arias, A. (1995). Serrate and wingless cooperate to induce vestigial gene expression and wing formation in Drosophila. Cur. Biol. 5, 1437-1448.
12. Couso, J. P. and Martinez-Arias, A. (1994). Notch is required for wingless signaling in the epidermis of Drosophila. Cell 79, 259-272.
13. de Celis, J. K. (1997). Expression and function of decapentaplegic and thick veins during the differentiation of the veins in the Drosophila wing. Development 124, 1007-18.
14. de Celis, J. F., Barrio, R., del Arco, A. and García-Bellido, A. (1993). Genetic and molecular characterization of a Notch mutation in its Delta-and Serrate-binding domain in Drosophila. Proc. Natl Acad. Sci. USA 90, 4037-4041.
15. de Celis, J. F. and Bray, S. (1997). Feed-back mechanisms affecting Notch activation at the dorsoventral boundary in the Drosophila wing. Development 124, 3241-3251.
16. de Celis, J. F., Bray, S. and Garcia-Bellido, A. (1997). Notch signalling regulates veinlet expression and establishes boundaries between veins and interveins in the Drosophila wing. Development 124, 1919-1928.
17. de Celis, J. F. and Garcia-Bellido, A. (1994). Modifications of the Notch function by Abruptes mutations in Drosophila melanogaster. Genetics 136, 183-194.
18. de Celis, J. F., Garcia-Bellido, A. and Bray, S. J. (1996). Activation and function of Notch at the dorsal-ventral boundary of the wing imaginal disc. Development 122, 359-369.
19. de Celis, J. F., Llimargas, M. and Casanova, J. (1995). ventral veinless, the gene encoding the Cf1a transcription factor, links positional information and cell differentiation during embryonic and imaginal development in Drosophila melanogaster. Development 121, 3405-3416.
20. de Celis, J. F., Mari-Beffa, M. and Garcia-Bellido, A. (1991a). Function of trans-acting genes of the achaetae-scute complex in sensory organ patterning in the mesonotum of Drosophila. Roux's Arch. Dev. Biol. 200, 64-76.
21. de Celis, J. F., Marí-Beffa, M. and García-Bellido, A. (1991b). Cell-autonomous role of Notch, an epidermal growth factor homologue, in sensory organ differentiation in Drosophila. Proc. Natl Acad. Sci. USA 88, 632-6366.
22. de Celis, J. F., Tyler, D. M., de Celis, J. and Bray, S. J. (1998). Notch signalling mediates segmentation of the Drosophila leg. Development 23, 4617-26.
23. de la Concha, A., Dietrich, U., Weigel, D. and Campos-Ortega, J. A. (1988). Functional interactions of neurogenic genes of Drosophila melanogaster. Genetics 118, 499-508.
24. Diaz-Benjumea, F. and Cohen, S. M. (1993). Interactions between dorsal and ventral cells in the imaginal disc directs wing development in Drosophila. Cell 75, 741-752.
25. Diaz-Benjumea, F. J. and Cohen, S. M. (1995). Serrate signals through Notch to establish a wingless-dependent organized at the dorsal/ventral compartment boundary of the Drosophila wing. Development 121, 4215-4225.
26. Doherty, D., Feger, G., Younger-Shepherd, S., Jan, L. Y. and Jan, Y. N. (1996). Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation. Genes Dev. 10, 421-434.
27. Dominguez, M. and de Celis, J. F. (1998). A dorsal/ventral boundary established by Notch controls growth and polarity in the Drosophila eye. Nature 396, 276-278.
28. Fehon, R. G., Johansen, K., Rebay, I. and Artavanis-Tsakonas, S. (1991). Complex cellular and subcellular regulation of Notch expression during embryonic and imaginal development of Drosophila: implications for Notch function. J. Cell Biol. 113, 657-669.
29. Fehon, R. G., Kooh, P. J., Rabay, I., Regan, C. L., Xu, T., Muskavitch, M. A. T. and Artavanis-Tsakonas, S. (1990). Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila. Cell 61, 523-534.
30. Fleming, R. J., Gu, Y. and Hukriede, N. A. (1997). Serrate-mediated activation of Notch is specifically blocked by the product of the gene fringe in the dorsal compartment of the Drosophila wing imaginal disc. Development 124, 2973-2981.
31. Foster, G. (1975). Negative complementation at the Notch locus of Drosophila melanogaster. Genetics 81, 99-120.
32. Gomez-Skarmeta, J. L., Diez del Corral, R., de la Calle, E., Ferrer-Marco, D. and Modolell, J. (1996). araucan and caupolican, two members of the novel Iroquois complex, encode homeoproteins that control proneural and vein-forming genes. Cell 85, 95-105.
33. Heitzler, P. and Simpson, P. (1993). Altered epidermal growth factor-like sequences provide evidence for a role of Notch as a receptor in cell fate decisions. Development 117, 1113-1123.
34. Heitzler, P. and Simpson, P. (1991). The choice of cell fate in the epidermis of Drosophila. Cell 64, 1032-1042.
35. Hing, H. K., Sun, X. and Artavanis-Tsakonas, S. (1994). Modulation of wingless signaling by Notch in Drosophila. Mech. Dev. 47, 261-268.
36. Hukriede, N. A., Gu, Y. and Fleming, R. J. (1997). A dominat-negative form of Serrate acts as a gneral antagonist of Notch activation. Development 124, 3427-3437.
37. Huppert, S., Jacobsen, T. and Muskavitch, M. A. T. (1997). Feedback regulation is central to Delta-Notch signalling required for Drosophila wing vein morphogenesis. Development 124, 3283-3291.
38. Irvine, K. D. and Vogt, T. F. (1997). Dorso-ventral signalling in limb development. Cur. Opin. Cell Biol. 9, 867-876.
39. Irvine, K. D. and Wieschaus, E. (1994). fringe, a boundary-specific signalling molecule, mediates interactions between dorsal and ventral cells during Drosophila wing development. Cell 79, 595-606.
40. Ito, K., Awano, W., Suzuki, K., Hiromi, Y. and Yamamoto, D. (1997). The Drosophila mushroom body is a quadruple structure of clonal units each of which contains a virtually identical set of neurones and glial cells. Development 124, 761-771.
41. Jack, J., Dorsett, D., Delotto, Y. and Liu, S. (1991). Expression of the cut locus in the Drosophila wing margin is required for cell type specification and is regulated by a distant enhancer. Development 113, 735-747.
42. Jonsson, F. and Knust, E. (1996). Distinct functions of the Drosophila genes Serrate and Delta revealed by ectopic expression during wing development. Dev. Genes Evol. 206, 91-101.
43. Kelley, M. R., Kidd, S., Deutsh, W. A. and Young, M. W. (1987). Mutations altering the structure of epidermal growth factor-like coding sequences at the Drosophila Notch locus. Cell 51, 539-548.
44. Kidd, S., Lockett T. and Young, M. W. (1983). The Notch locus of Drosophila melanogaster. Cell 34, 421-433.
45. Kim, J., Irvine, K. D. and Carroll, S. B. (1995). Cell recognition, signal induction, and symmetrical gene activation at the dorsal-ventral boundary of the developing Drosophila wing. Cell 82, 795-802.
46. Klein, T., Brennan, K., & Martinez-Arias, A. (1997). An intrinsic dominant negative activity of Serrate that is modulated during wing development in Drosophila. Dev. Biol. 186
47. Klein, T. and Martinez-Arias, A. (1998). Interactions among Delta, Serrate and Fringe modulate Notch activity during Drosophila wing development. Development 125, 2951-2962.
48. Kooh, P. J., Fehon, R. G. and Muskavitch, A. T. (1993). Implications of dynamic patterns of Delta and Notch expression for cellular interactions during Drosophila development. Development 117, 493-507.
49. Kopan, R., Schroeter, E. H., Weintraub, H. and Nye, J. S. (1996). Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain. Proc. Natl Acad. Sci. USA 93, 1683-1688.
50. Lecourtois, M. and Schweisguth, F. (1995). The neurogenic Suppressor of Hairless DNA-binding protein mediates the transcriptional activation of the Enhancer of split Complex genes triggered by Notch signalling. Genes Dev. 9, 2598-2608.
51. Lecourtois, M. and Schweisguth, F. (1998). Indirect evidence for Delta-dependent intracellular processing of Notch in Drosophila embryos. Cur. Biol. 8, 771-774.
52. Lecuit, T. and Cohen, S. M. (1997). Proximal-distal axis formation in the Drosophila leg. Nature 388, 139-145.
53. Lieber, T., Wesley, C. S., Alcamo, E., Hassel, B., Krane, J. F., Campos-Ortega, J. A., & Young, M. W. (1992). Single amino acid sustitutions in EGF-like elements of Notch and Delta modify Drosophila development and affect cell adhesion in vitro. Neuron 9, 847-859.
54. Lindsley, D. and Zimm, G. G. (1992). The Genome of Drosophila melanogaster. San Diego, USA: Academic Press Inc.
55. Micchelli, C. A. and Blair, S. S. (1999). Dorsoventral lineage restriction in wing imaginal discs requires Notch. Nature 401, 473-475.
56. Micchelli, C. A., Rulifson, E. J. and Blair, S. (1997). The function and regulation of cut expression on the wing margin of Drosophila: Notch, Wingless and a dominant negative role for Delta and Serrate. Development 124, 1485-1495.
57. Muskavitch, M. A. T. (1994). Delta-Notch signaling and Drosophila cell fate choice. Dev. Biol. 166, 415-430.
58. Nye, J. S. and Kopan, R. (1995). Vertebrate ligands for Notch. Cur. Biol. 5, 966-969.
59. Panin, V. M., Papayannopoulos, V., Wilson, R. and Irvine, K. D. (1997). Fringe modulates Notch-ligand interactions. Nature 387, 908-912.
60. Papayannopoulos, V., Tomlinson, A., Panin, V. M., Rauskolb, C. and Irvine, K. D. (1998). Dorsal-ventral signaling in the Drosophila eye. Science 281, 2031-4.
61. Portin, P. (1975). Allelic negative complementation at the Abruptex locus of Drosophila melanogaster. Genetics 81, 99-120.
62. Portin, P. (1977). Effects of temperature on interactions of Abruptex and recessive alleles of the Notch complex locus of Drosophila melanogaster. Hereditas 87, 77-84.
63. Portin, P. and Sirem, M. (1976). Timing of temperature-sensitive period for lethality of Abruptex mutations of Drosophila melanogaster. Hereditas 84, 109-116.
64. Rauskolb, C., Correia, T. and Irvine, K. D. (1999). Fringe-dependent separation of dorsal and ventral cells in the Drosophila wing. Nature 401, 476-480.
65. Rebay, I., Fleming, R. J., Fehon, R. G., Chervas, P. and Artavanis-Tsakonas, S. (1991). Specific EGF repeats of Notch mediate interactions with Delta and Serrate: implications for Notch as a multifunctional receptor. Cell 67, 687-699.
66. Speicher, S. A., Thomas, U., Hinz, U. and Knust, E. (1994). The Serrate locus of Drosophila and its role in morphogenesis of the wing imaginal discs: control of cell proliferation. Development 120, 535-544.
67. Struhl, G. and Adachi, A. (1998). Nuclear access and action of Notch in vivo. Cell 93, 649-660.
68. Tamura, K., Taniguchi, Y., Minoguchi, S., Kakai, T., Tun, T., Furukawa, T. and Honjo, T. (1995). Physical interactions between a novel domain of the receptor Notch and the transcription factor RBP-Jk/Su(H). Cur. Biol. 5, 1416-1423.
69. D, a dominant allele of the Drosophila gene Serrate. Genetics 139, 203-213.
70. Yuan, Y. P., Schultz, J., Mlodzik, M. and Bork, P. (1997). Secreted Fringe-like signaling molecules may be glycosyltransferases. Cell 88, 9-11.
71. Zecca, M., Basler, K. and Struhl, G. (1996). Direct and long-range action of a Wingless morphogen gradient. Cell 87, 833-844.