Advanced intravital subcellular imaging reveals vital three-dimensional signalling events driving cancer cell behaviour and drug responses in live tissue

FEBS Journal

Volumn 280, Issue 21, 2013, Pages 5177-5197

  Nobis, Max ^a   Carragher, Neil O ^b   McGhee, Ewan J ^a   Morton, Jennifer P ^a   Sansom, Owen J ^a   Anderson, Kurt I ^a   Timpson, Paul ^c,d  

^a BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^d UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

adhesions; biosensors; drug discovery; fluorescence lifetime imaging microscopy; fluorescence recovery after photobleaching; fluorescence resonance energy transfer; intravital imaging; invasion; metastasis; optical windows

Indexed keywords

GREEN FLUORESCENT PROTEIN; RED FLUORESCENT PROTEIN; TRANSFORMING GROWTH FACTOR BETA; YELLOW FLUORESCENT PROTEIN;

BIOSENSOR; CANCER CELL; CANCER MODEL; CELL INVASION; CELL MIGRATION; CELL TRACKING; CONFERENCE PAPER; EXTRACELLULAR MATRIX; FLUORESCENCE MICROSCOPY; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; FLUORESCENCE RESONANCE ENERGY TRANSFER; FLUORESCENT LIFETIME IMAGING MICROSCOPY; IMAGING; INTRAVITAL IMAGING; METASTASIS; MOLECULAR DYNAMICS; NONHUMAN; PHARMACODYNAMICS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; THREE DIMENSIONAL IMAGING; TUMOR ASSOCIATED LEUKOCYTE; TUMOR INVASION; TUMOR MICROENVIRONMENT;

ADHESIONS; BIOSENSORS; DRUG DISCOVERY; FLUORESCENCE LIFETIME IMAGING MICROSCOPY; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; FLUORESCENCE RESONANCE ENERGY TRANSFER; INTRAVITAL IMAGING; INVASION; METASTASIS; OPTICAL WINDOWS;

ANIMALS; ANTINEOPLASTIC AGENTS; DIAGNOSTIC IMAGING; DRUG DISCOVERY; HUMANS; MICROSCOPY, FLUORESCENCE; NEOPLASMS; SIGNAL TRANSDUCTION; TUMOR MICROENVIRONMENT;

EID: 84886099515     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12348     Document Type: Conference Paper

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