FLIM-FRET imaging in vivo reveals 3D-environment spatially regulates RhoGTPase activity during cancer cell invasion

Small GTPases

Volumn 2, Issue 4, 2011, Pages 239-244

  McGhee, Ewan J ^a   Morton, Jennifer P ^a   von Kriegsheim, Alex ^a   Schwarz, Juliane P ^a   Karim, Saadia A ^a   Carragher, Neil O ^b   Sansom, Owen J ^a   Anderson, Kurt I ^a   Timpson, Paul ^a  

^a BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Biosensor; FLIM; FRET; Intravital imaging; Invasion; Metastasis; RhoGTPases

Indexed keywords

PROTEIN P53; RAC1 PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ARTICLE; CANCER CELL; CANCER INVASION; DRUG SCREENING; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME REGULATION; FLUORESCENCE IMAGING; FLUORESCENCE LIFETIME IMAGING MICROSCOPY; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMAN; IN VIVO STUDY; MOLECULAR IMAGING; NONHUMAN; SIGNAL TRANSDUCTION; TUMOR MICROENVIRONMENT;

EID: 80053313416     PISSN: 21541248     EISSN: 21541256     Source Type: Journal    
DOI: 10.4161/sgtp.2.4.17275     Document Type: Article

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