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Volumn 100, Issue 2, 2013, Pages 473-486

Insights from host genomics into HIV infection and disease: Identification of host targets for drug development

Author keywords

Genetic variation; HIV; HIV disease phenotype; Host factor; Human genomics; Novel antiviral therapy

Indexed keywords

ABACAVIR; ANTIVIRUS AGENT; APLAVIROC; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3G; ATAZANAVIR; CENICRIVIROC; CYTOKINE; EFAVIRENZ; EFAVIRENZ PLUS EMTRICITABINE PLUS TENOFOVIR DISOPROXIL; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; INDINAVIR PLUS LOPINAVIR; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; MARAVIROC; NELFINAVIR; NEVIRAPINE; PRO 140; RALTEGRAVIR; RITONAVIR; SAQUINAVIR; SMALL INTERFERING RNA; TENOFOVIR; TRANSCRIPTOME; TRIPARTITE MOTIF PROTEIN 5; UNCLASSIFIED DRUG; VICRIVIROC; ZIDOVUDINE; HOST FACTOR;

EID: 84885509308     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2013.09.017     Document Type: Review
Times cited : (11)

References (174)
  • 1
    • 70349220934 scopus 로고    scopus 로고
    • Human genetics of infectious diseases: Between proof of principle and paradigm
    • A. Alcais, L. Abel, and J.L. Casanova Human genetics of infectious diseases: between proof of principle and paradigm J. Clin. Invest. 119 2009 2506 2514
    • (2009) J. Clin. Invest. , vol.119 , pp. 2506-2514
    • Alcais, A.1    Abel, L.2    Casanova, J.L.3
  • 2
    • 84862849229 scopus 로고    scopus 로고
    • Synthesis and structure-activity relationship studies of HIV-1 virion infectivity factor (Vif) inhibitors that block viral replication
    • A. Ali, J. Wang, R.S. Nathans, H. Cao, N. Sharova, M. Stevenson, and T.M. Rana Synthesis and structure-activity relationship studies of HIV-1 virion infectivity factor (Vif) inhibitors that block viral replication ChemMedChem 7 2012 1217 1229
    • (2012) ChemMedChem , vol.7 , pp. 1217-1229
    • Ali, A.1    Wang, J.2    Nathans, R.S.3    Cao, H.4    Sharova, N.5    Stevenson, M.6    Rana, T.M.7
  • 3
    • 79953117041 scopus 로고    scopus 로고
    • Evidence for the cure of HIV infection by CCR5Delta32/Delta32 stem cell transplantation
    • K. Allers, G. Hutter, J. Hofmann, C. Loddenkemper, K. Rieger, E. Thiel, and T. Schneider Evidence for the cure of HIV infection by CCR5Delta32/Delta32 stem cell transplantation Blood 117 2011 2791 2799
    • (2011) Blood , vol.117 , pp. 2791-2799
    • Allers, K.1    Hutter, G.2    Hofmann, J.3    Loddenkemper, C.4    Rieger, K.5    Thiel, E.6    Schneider, T.7
  • 6
    • 0041314090 scopus 로고    scopus 로고
    • A tumor necrosis factor-alpha-inducible promoter variant of interferon-gamma accelerates CD4+ T cell depletion in human immunodeficiency virus-1-infected individuals
    • P. An, D. Vlahov, J.B. Margolick, J. Phair, T.R. O'Brien, J. Lautenberger, S.J. O'Brien, and C.A. Winkler A tumor necrosis factor-alpha-inducible promoter variant of interferon-gamma accelerates CD4+ T cell depletion in human immunodeficiency virus-1-infected individuals J. Infect. Dis. 188 2003 228 231
    • (2003) J. Infect. Dis. , vol.188 , pp. 228-231
    • An, P.1    Vlahov, D.2    Margolick, J.B.3    Phair, J.4    O'Brien, T.R.5    Lautenberger, J.6    O'Brien, S.J.7    Winkler, C.A.8
  • 8
    • 76749167054 scopus 로고    scopus 로고
    • Host genes associated with HIV/AIDS: Advances in gene discovery
    • P. An, and C.A. Winkler Host genes associated with HIV/AIDS: advances in gene discovery Trends Genet. 26 2010 119 131
    • (2010) Trends Genet. , vol.26 , pp. 119-131
    • An, P.1    Winkler, C.A.2
  • 9
    • 79952699573 scopus 로고    scopus 로고
    • The search for host genetic factors of HIV/AIDS pathogenesis in the post-genome era: Progress to date and new avenues for discovery
    • B.E. Aouizerat, C.L. Pearce, and C. Miaskowski The search for host genetic factors of HIV/AIDS pathogenesis in the post-genome era: progress to date and new avenues for discovery Curr. HIV/AIDS Rep. 8 2011 38 44
    • (2011) Curr. HIV/AIDS Rep. , vol.8 , pp. 38-44
    • Aouizerat, B.E.1    Pearce, C.L.2    Miaskowski, C.3
  • 12
    • 34248531947 scopus 로고    scopus 로고
    • Polymorphisms in IRF-1 associated with resistance to HIV-1 infection in highly exposed uninfected Kenyan sex workers
    • T.B. Ball, H. Ji, J. Kimani, P. McLaren, C. Marlin, A.V. Hill, and F.A. Plummer Polymorphisms in IRF-1 associated with resistance to HIV-1 infection in highly exposed uninfected Kenyan sex workers AIDS 21 2007 1091 1101
    • (2007) AIDS , vol.21 , pp. 1091-1101
    • Ball, T.B.1    Ji, H.2    Kimani, J.3    McLaren, P.4    Marlin, C.5    Hill, A.V.6    Plummer, F.A.7
  • 13
    • 84864475970 scopus 로고    scopus 로고
    • HIV-1 infection and CCR5D32 homozygosis
    • E. Ballana, and J.A. Este HIV-1 infection and CCR5D32 homozygosis Future Virol. 7 2012 1 6
    • (2012) Future Virol. , vol.7 , pp. 1-6
    • Ballana, E.1    Este, J.A.2
  • 14
    • 84856860485 scopus 로고    scopus 로고
    • Rare LEDGF/p75 genetic variants in white long-term nonprogressor HIV+ individuals
    • E. Ballana, E. Gonzalo, E. Grau, J.A. Iribarren, B. Clotet, and J.A. Este Rare LEDGF/p75 genetic variants in white long-term nonprogressor HIV+ individuals AIDS 26 2012 527 528
    • (2012) AIDS , vol.26 , pp. 527-528
    • Ballana, E.1    Gonzalo, E.2    Grau, E.3    Iribarren, J.A.4    Clotet, B.5    Este, J.A.6
  • 17
    • 49849095345 scopus 로고    scopus 로고
    • Single-nucleotide polymorphisms in human beta-defensin-1 gene in Mozambican HIV-1-infected women and correlation with virologic parameters
    • S. Baroncelli, E. Ricci, M. Andreotti, G. Guidotti, P. Germano, M.C. Marazzi, S. Vella, L. Palombi, A. De Rossi, and M. Giuliano Single-nucleotide polymorphisms in human beta-defensin-1 gene in Mozambican HIV-1-infected women and correlation with virologic parameters AIDS 22 2008 1515 1517
    • (2008) AIDS , vol.22 , pp. 1515-1517
    • Baroncelli, S.1    Ricci, E.2    Andreotti, M.3    Guidotti, G.4    Germano, P.5    Marazzi, M.C.6    Vella, S.7    Palombi, L.8    De Rossi, A.9    Giuliano, M.10
  • 19
    • 80052830258 scopus 로고    scopus 로고
    • Molecular strategies to design an escape-proof antiviral therapy
    • B. Berkhout, and R.W. Sanders Molecular strategies to design an escape-proof antiviral therapy Antiviral Res. 92 2011 7 14
    • (2011) Antiviral Res. , vol.92 , pp. 7-14
    • Berkhout, B.1    Sanders, R.W.2
  • 20
    • 26444480661 scopus 로고    scopus 로고
    • Use of a combined ex vivo/in vivo population approach for screening of human genes involved in the human immunodeficiency virus type 1 life cycle for variants influencing disease progression
    • G. Bleiber, M. May, R. Martinez, P. Meylan, J. Ott, J.S. Beckmann, and A. Telenti Use of a combined ex vivo/in vivo population approach for screening of human genes involved in the human immunodeficiency virus type 1 life cycle for variants influencing disease progression J. Virol. 79 2005 12674 12680
    • (2005) J. Virol. , vol.79 , pp. 12674-12680
    • Bleiber, G.1    May, M.2    Martinez, R.3    Meylan, P.4    Ott, J.5    Beckmann, J.S.6    Telenti, A.7
  • 23
    • 3843064497 scopus 로고    scopus 로고
    • A single-nucleotide polymorphism in the human beta-defensin 1 gene is associated with HIV-1 infection in Italian children
    • L. Braida, M. Boniotto, A. Pontillo, P.A. Tovo, A. Amoroso, and S. Crovella A single-nucleotide polymorphism in the human beta-defensin 1 gene is associated with HIV-1 infection in Italian children AIDS 18 2004 1598 1600
    • (2004) AIDS , vol.18 , pp. 1598-1600
    • Braida, L.1    Boniotto, M.2    Pontillo, A.3    Tovo, P.A.4    Amoroso, A.5    Crovella, S.6
  • 25
    • 73549103358 scopus 로고    scopus 로고
    • The development of antiretroviral therapy and its impact on the HIV-1/AIDS pandemic
    • S. Broder The development of antiretroviral therapy and its impact on the HIV-1/AIDS pandemic Antiviral Res. 85 2010 1 18
    • (2010) Antiviral Res. , vol.85 , pp. 1-18
    • Broder, S.1
  • 26
    • 84867399523 scopus 로고    scopus 로고
    • Modulation of HIV reservoirs by host HLA: Bridging the gap between vaccine and cure
    • Z.L. Brumme, D.R. Chopera, and M.A. Brockman Modulation of HIV reservoirs by host HLA: bridging the gap between vaccine and cure Curr. Opin. Virol. 2 2012 599 605
    • (2012) Curr. Opin. Virol. , vol.2 , pp. 599-605
    • Brumme, Z.L.1    Chopera, D.R.2    Brockman, M.A.3
  • 28
    • 0032837669 scopus 로고    scopus 로고
    • Genetics of HIV-1 infection: Chemokine receptor CCR5 polymorphism and its consequences
    • M. Carrington, M. Dean, M.P. Martin, and S.J. O'Brien Genetics of HIV-1 infection: chemokine receptor CCR5 polymorphism and its consequences Hum. Mol. Genet. 8 1999 1939 1945
    • (1999) Hum. Mol. Genet. , vol.8 , pp. 1939-1945
    • Carrington, M.1    Dean, M.2    Martin, M.P.3    O'Brien, S.J.4
  • 32
    • 0038581912 scopus 로고    scopus 로고
    • The influence of HLA genotype on AIDS
    • M. Carrington, and S.J. O'Brien The influence of HLA genotype on AIDS Annu. Rev. Med. 54 2003 535 551
    • (2003) Annu. Rev. Med. , vol.54 , pp. 535-551
    • Carrington, M.1    O'Brien, S.J.2
  • 35
    • 79959524146 scopus 로고    scopus 로고
    • A haplotype map of the human genome
    • H. Consortium A haplotype map of the human genome Nature 437 2005 1299 1320
    • (2005) Nature , vol.437 , pp. 1299-1320
    • Consortium, H.1
  • 39
    • 0025735965 scopus 로고
    • Transient high levels of viremia in patients with primary human immunodeficiency virus type 1 infection
    • E.S. Daar, T. Moudgil, R.D. Meyer, and D.D. Ho Transient high levels of viremia in patients with primary human immunodeficiency virus type 1 infection N. Engl. J. Med. 324 1991 961 964
    • (1991) N. Engl. J. Med. , vol.324 , pp. 961-964
    • Daar, E.S.1    Moudgil, T.2    Meyer, R.D.3    Ho, D.D.4
  • 50
    • 78650904206 scopus 로고    scopus 로고
    • Long-term inhibition of HIV-1 replication with RNA interference against cellular co-factors
    • J.J. Eekels, D. Geerts, R.E. Jeeninga, and B. Berkhout Long-term inhibition of HIV-1 replication with RNA interference against cellular co-factors Antiviral Res. 89 2011 43 53
    • (2011) Antiviral Res. , vol.89 , pp. 43-53
    • Eekels, J.J.1    Geerts, D.2    Jeeninga, R.E.3    Berkhout, B.4
  • 52
    • 84867402015 scopus 로고    scopus 로고
    • Regulators of innate immunity as novel targets for panviral therapeutics
    • S. Es-Saad, N. Tremblay, M. Baril, and D. Lamarre Regulators of innate immunity as novel targets for panviral therapeutics Curr. Opin. Virol. 2 2012 622 628
    • (2012) Curr. Opin. Virol. , vol.2 , pp. 622-628
    • Es-Saad, S.1    Tremblay, N.2    Baril, M.3    Lamarre, D.4
  • 54
    • 34347378496 scopus 로고    scopus 로고
    • HIV entry inhibitors
    • J.A. Este, and A. Telenti HIV entry inhibitors Lancet 370 2007 81 88
    • (2007) Lancet , vol.370 , pp. 81-88
    • Este, J.A.1    Telenti, A.2
  • 55
    • 84864149258 scopus 로고    scopus 로고
    • Toward an AIDS-free generation
    • A.S. Fauci, and G.K. Folkers Toward an AIDS-free generation JAMA 308 2012 343 344
    • (2012) JAMA , vol.308 , pp. 343-344
    • Fauci, A.S.1    Folkers, G.K.2
  • 65
    • 33750481554 scopus 로고    scopus 로고
    • Microarray data on gene modulation by HIV-1 in immune cells: 2000-2006
    • M.S. Giri, M. Nebozhyn, L. Showe, and L.J. Montaner Microarray data on gene modulation by HIV-1 in immune cells: 2000-2006 J. Leukocyte Biol. 80 2006 1031 1043
    • (2006) J. Leukocyte Biol. , vol.80 , pp. 1031-1043
    • Giri, M.S.1    Nebozhyn, M.2    Showe, L.3    Montaner, L.J.4
  • 69
    • 53949113588 scopus 로고    scopus 로고
    • Single-molecule DNA sequencing technologies for future genomics research
    • P.K. Gupta Single-molecule DNA sequencing technologies for future genomics research Trends Biotechnol. 26 2008 602 611
    • (2008) Trends Biotechnol. , vol.26 , pp. 602-611
    • Gupta, P.K.1
  • 70
    • 61549117852 scopus 로고    scopus 로고
    • High-throughput screening of HCV RNA replication inhibitors by means of a reporter replicon system
    • W. Hao, and R. Duggal High-throughput screening of HCV RNA replication inhibitors by means of a reporter replicon system Methods Mol. Biol. 510 2009 243 250
    • (2009) Methods Mol. Biol. , vol.510 , pp. 243-250
    • Hao, W.1    Duggal, R.2
  • 71
    • 84875969816 scopus 로고    scopus 로고
    • Entry inhibitors and their use in the treatment of HIV-1 infection
    • A.A. Haqqani, and J.C. Tilton Entry inhibitors and their use in the treatment of HIV-1 infection Antiviral Res. 98 2013 158 170
    • (2013) Antiviral Res. , vol.98 , pp. 158-170
    • Haqqani, A.A.1    Tilton, J.C.2
  • 74
    • 33750457001 scopus 로고    scopus 로고
    • Type i interferon production in HIV-infected patients
    • A. Hosmalin, and P. Lebon Type I interferon production in HIV-infected patients J. Leukocyte Biol. 80 2006 984 993
    • (2006) J. Leukocyte Biol. , vol.80 , pp. 984-993
    • Hosmalin, A.1    Lebon, P.2
  • 77
    • 33947419675 scopus 로고    scopus 로고
    • Distinct transcriptional profiles in ex vivo CD4+ and CD8+ T cells are established early in human immunodeficiency virus type 1 infection and are characterized by a chronic interferon response as well as extensive transcriptional changes in CD8+ T cells
    • M.D. Hyrcza, C. Kovacs, M. Loutfy, R. Halpenny, L. Heisler, S. Yang, O. Wilkins, M. Ostrowski, and S.D. Der Distinct transcriptional profiles in ex vivo CD4+ and CD8+ T cells are established early in human immunodeficiency virus type 1 infection and are characterized by a chronic interferon response as well as extensive transcriptional changes in CD8+ T cells J. Virol. 81 2007 3477 3486
    • (2007) J. Virol. , vol.81 , pp. 3477-3486
    • Hyrcza, M.D.1    Kovacs, C.2    Loutfy, M.3    Halpenny, R.4    Heisler, L.5    Yang, S.6    Wilkins, O.7    Ostrowski, M.8    Der, S.D.9
  • 81
    • 0345064728 scopus 로고    scopus 로고
    • Acute human immunodeficiency virus type 1 infection
    • J.O. Kahn, and B.D. Walker Acute human immunodeficiency virus type 1 infection N. Engl. J. Med. 339 1998 33 39
    • (1998) N. Engl. J. Med. , vol.339 , pp. 33-39
    • Kahn, J.O.1    Walker, B.D.2
  • 85
    • 84873349819 scopus 로고    scopus 로고
    • Polymorphic LEDGF/p75 variants support efficient HIV-1 infection ex vivo
    • Y. Koh, E. Ballana, J. Este, and A. Engelman Polymorphic LEDGF/p75 variants support efficient HIV-1 infection ex vivo AIDS 27 2013 665 667
    • (2013) AIDS , vol.27 , pp. 665-667
    • Koh, Y.1    Ballana, E.2    Este, J.3    Engelman, A.4
  • 94
    • 0038555813 scopus 로고    scopus 로고
    • Association of polymorphisms in human leukocyte antigen class i and transporter associated with antigen processing genes with resistance to human immunodeficiency virus type 1 infection
    • C. Liu, M. Carrington, R.A. Kaslow, X. Gao, C.R. Rinaldo, L.P. Jacobson, J.B. Margolick, J. Phair, S.J. O'Brien, and R. Detels Association of polymorphisms in human leukocyte antigen class I and transporter associated with antigen processing genes with resistance to human immunodeficiency virus type 1 infection J. Infect. Dis. 187 2003 1404 1410
    • (2003) J. Infect. Dis. , vol.187 , pp. 1404-1410
    • Liu, C.1    Carrington, M.2    Kaslow, R.A.3    Gao, X.4    Rinaldo, C.R.5    Jacobson, L.P.6    Margolick, J.B.7    Phair, J.8    O'Brien, S.J.9    Detels, R.10
  • 102
    • 49249137457 scopus 로고    scopus 로고
    • Development of an HTS assay for the search of anti-influenza agents targeting the interaction of viral RNA with the NS1 protein
    • M. Maroto, Y. Fernandez, J. Ortin, F. Pelaez, and M.A. Cabello Development of an HTS assay for the search of anti-influenza agents targeting the interaction of viral RNA with the NS1 protein J. Biomol. Screen 13 2008 581 590
    • (2008) J. Biomol. Screen , vol.13 , pp. 581-590
    • Maroto, M.1    Fernandez, Y.2    Ortin, J.3    Pelaez, F.4    Cabello, M.A.5
  • 108
  • 109
    • 84875010204 scopus 로고    scopus 로고
    • Molecular basis of human immunodeficiency virus type 1 drug resistance. Overview and recent developments
    • L. Menendez-Arias Molecular basis of human immunodeficiency virus type 1 drug resistance. Overview and recent developments Antiviral Res. 98 2013 93 120
    • (2013) Antiviral Res. , vol.98 , pp. 93-120
    • Menendez-Arias, L.1
  • 110
    • 84930480295 scopus 로고    scopus 로고
    • The dual role of pharmacogenetics in HIV treatment: Mutations and polymorphisms regulating antiretroviral drug resistance and disposition
    • V. Michaud, T. Bar-Magen, J. Turgeon, D. Flockhart, Z. Desta, and M.A. Wainberg The dual role of pharmacogenetics in HIV treatment: mutations and polymorphisms regulating antiretroviral drug resistance and disposition Pharmacol. Rev. 64 2012 803 833
    • (2012) Pharmacol. Rev. , vol.64 , pp. 803-833
    • Michaud, V.1    Bar-Magen, T.2    Turgeon, J.3    Flockhart, D.4    Desta, Z.5    Wainberg, M.A.6
  • 111
    • 33746768204 scopus 로고    scopus 로고
    • DEFB1 gene polymorphisms and increased risk of HIV-1 infection in Brazilian children
    • M. Milanese, L. Segat, A. Pontillo, L.C. Arraes, J.L. de Lima Filho, and S. Crovella DEFB1 gene polymorphisms and increased risk of HIV-1 infection in Brazilian children AIDS 20 2006 1673 1675
    • (2006) AIDS , vol.20 , pp. 1673-1675
    • Milanese, M.1    Segat, L.2    Pontillo, A.3    Arraes, L.C.4    De Lima Filho, J.L.5    Crovella, S.6
  • 115
    • 37349119039 scopus 로고    scopus 로고
    • HIV-1 escape to CCR5 coreceptor antagonism through selection of CXCR4-using variants in vitro
    • G. Moncunill, M. Armand-Ugon, E. Pauls, B. Clotet, and J.A. Este HIV-1 escape to CCR5 coreceptor antagonism through selection of CXCR4-using variants in vitro AIDS 22 2008 23 31
    • (2008) AIDS , vol.22 , pp. 23-31
    • Moncunill, G.1    Armand-Ugon, M.2    Pauls, E.3    Clotet, B.4    Este, J.A.5
  • 117
    • 61849090826 scopus 로고    scopus 로고
    • Confirmation of differential binding of Interferon Regulatory Factor-1 (IRF-1) to the functional and HIV disease-influencing-2578 A/G polymorphism in CCL2
    • author reply 199
    • S. Mummidi, G.B. Bonello, and S.K. Ahuja Confirmation of differential binding of Interferon Regulatory Factor-1 (IRF-1) to the functional and HIV disease-influencing-2578 A/G polymorphism in CCL2 Genes Immun. 10 2009 197 198 author reply 199
    • (2009) Genes Immun. , vol.10 , pp. 197-198
    • Mummidi, S.1    Bonello, G.B.2    Ahuja, S.K.3
  • 122
    • 2642563503 scopus 로고    scopus 로고
    • Human genes that limit AIDS
    • S.J. O'Brien, and G.W. Nelson Human genes that limit AIDS Nat. Genet. 36 2004 565 574
    • (2004) Nat. Genet. , vol.36 , pp. 565-574
    • O'Brien, S.J.1    Nelson, G.W.2
  • 124
    • 0032903104 scopus 로고    scopus 로고
    • Analysis of the CC chemokine receptor 5 m303 mutation in infants born to HIV-1-seropositive mothers
    • L. Ometto, R. Bertorelle, M. Mainardi, M. Giurisato, L. Chieco-Bianchi, and A. De Rossi Analysis of the CC chemokine receptor 5 m303 mutation in infants born to HIV-1-seropositive mothers AIDS 13 1999 871 872
    • (1999) AIDS , vol.13 , pp. 871-872
    • Ometto, L.1    Bertorelle, R.2    Mainardi, M.3    Giurisato, M.4    Chieco-Bianchi, L.5    De Rossi, A.6
  • 125
    • 84879880354 scopus 로고    scopus 로고
    • Restrictions to HIV-1 replication in resting CD4+ T lymphocytes
    • X. Pan, H.M. Baldauf, O.T. Keppler, and O.T. Fackler Restrictions to HIV-1 replication in resting CD4+ T lymphocytes Cell Res. 23 2013 876 885
    • (2013) Cell Res. , vol.23 , pp. 876-885
    • Pan, X.1    Baldauf, H.M.2    Keppler, O.T.3    Fackler, O.T.4
  • 126
    • 84871988769 scopus 로고    scopus 로고
    • Nucleotide embargo by SAMHD1: A strategy to block retroviral infection
    • E. Pauls, E. Ballana, and J.A. Este Nucleotide embargo by SAMHD1: a strategy to block retroviral infection Antiviral Res. 97 2013 180 182
    • (2013) Antiviral Res. , vol.97 , pp. 180-182
    • Pauls, E.1    Ballana, E.2    Este, J.A.3
  • 130
    • 72949104926 scopus 로고    scopus 로고
    • Polymorphisms in toll-like receptor 4 and toll-like receptor 9 influence viral load in a seroincident cohort of HIV-1-infected individuals
    • S.O. Pine, M.J. McElrath, and P.Y. Bochud Polymorphisms in toll-like receptor 4 and toll-like receptor 9 influence viral load in a seroincident cohort of HIV-1-infected individuals AIDS 23 2009 2387 2395
    • (2009) AIDS , vol.23 , pp. 2387-2395
    • Pine, S.O.1    McElrath, M.J.2    Bochud, P.Y.3
  • 133
    • 20344399376 scopus 로고    scopus 로고
    • The HIV coreceptor switch: A population dynamical perspective
    • R.R. Regoes, and S. Bonhoeffer The HIV coreceptor switch: a population dynamical perspective Trends Microbiol. 13 2005 269 277
    • (2005) Trends Microbiol. , vol.13 , pp. 269-277
    • Regoes, R.R.1    Bonhoeffer, S.2
  • 134
    • 58049092568 scopus 로고    scopus 로고
    • Polymorphisms in the regulatory region of the Cyclophilin A gene influence the susceptibility for HIV-1 infection
    • M.A. Rits, K.A. van Dort, and N.A. Kootstra Polymorphisms in the regulatory region of the Cyclophilin A gene influence the susceptibility for HIV-1 infection PLoS One 3 2008 e3975
    • (2008) PLoS One , vol.3 , pp. 3975
    • Rits, M.A.1    Van Dort, K.A.2    Kootstra, N.A.3
  • 139
    • 0030835663 scopus 로고    scopus 로고
    • Bicyclams, a class of potent anti-HIV agents, are targeted at the HIV coreceptor fusin/CXCR-4
    • D. Schols, J.A. Este, G. Henson, and E. De Clercq Bicyclams, a class of potent anti-HIV agents, are targeted at the HIV coreceptor fusin/CXCR-4 Antiviral Res. 35 1997 147 156
    • (1997) Antiviral Res. , vol.35 , pp. 147-156
    • Schols, D.1    Este, J.A.2    Henson, G.3    De Clercq, E.4
  • 142
    • 37749031255 scopus 로고    scopus 로고
    • Next-generation sequencing transforms today's biology
    • S.C. Schuster Next-generation sequencing transforms today's biology Nat. Methods 5 2008 16 18
    • (2008) Nat. Methods , vol.5 , pp. 16-18
    • Schuster, S.C.1
  • 143
    • 0034769960 scopus 로고    scopus 로고
    • Viruses and interferons
    • G.C. Sen Viruses and interferons Annu. Rev. Microbiol. 55 2001 255 281
    • (2001) Annu. Rev. Microbiol. , vol.55 , pp. 255-281
    • Sen, G.C.1
  • 144
    • 33646465596 scopus 로고    scopus 로고
    • Understanding the "lucky few": The conundrum of HIV-exposed, seronegative individuals
    • B.L. Shacklett Understanding the "lucky few": the conundrum of HIV-exposed, seronegative individuals Curr. HIV/AIDS Rep. 3 2006 26 31
    • (2006) Curr. HIV/AIDS Rep. , vol.3 , pp. 26-31
    • Shacklett, B.L.1
  • 145
    • 0037043699 scopus 로고    scopus 로고
    • Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein
    • A.M. Sheehy, N.C. Gaddis, J.D. Choi, and M.H. Malim Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein Nature 418 2002 646 650
    • (2002) Nature , vol.418 , pp. 646-650
    • Sheehy, A.M.1    Gaddis, N.C.2    Choi, J.D.3    Malim, M.H.4
  • 147
    • 33645038567 scopus 로고    scopus 로고
    • Impact of MCP-1-2518-G allele on the HIV-1 disease of children in the United States
    • K.K. Singh, M.D. Hughes, J. Chen, and S.A. Spector Impact of MCP-1-2518-G allele on the HIV-1 disease of children in the United States AIDS 20 2006 475 478
    • (2006) AIDS , vol.20 , pp. 475-478
    • Singh, K.K.1    Hughes, M.D.2    Chen, J.3    Spector, S.A.4
  • 150
    • 80051799415 scopus 로고    scopus 로고
    • Host genetic polymorphisms associated with innate immune factors and HIV-1
    • M.E. Sobieszczyk, J.R. Lingappa, and M.J. McElrath Host genetic polymorphisms associated with innate immune factors and HIV-1 Curr. Opin. HIV AIDS 6 2011 427 434
    • (2011) Curr. Opin. HIV AIDS , vol.6 , pp. 427-434
    • Sobieszczyk, M.E.1    Lingappa, J.R.2    McElrath, M.J.3
  • 152
    • 77950343791 scopus 로고    scopus 로고
    • Pattern recognition receptors and inflammation
    • O. Takeuchi, and S. Akira Pattern recognition receptors and inflammation Cell 140 2010 805 820
    • (2010) Cell , vol.140 , pp. 805-820
    • Takeuchi, O.1    Akira, S.2
  • 153
    • 0036318823 scopus 로고    scopus 로고
    • Favorable and unfavorable HLA class i alleles and haplotypes in Zambians predominantly infected with clade C human immunodeficiency virus type 1
    • J. Tang, S. Tang, E. Lobashevsky, A.D. Myracle, U. Fideli, G. Aldrovandi, S. Allen, R. Musonda, and R.A. Kaslow Favorable and unfavorable HLA class I alleles and haplotypes in Zambians predominantly infected with clade C human immunodeficiency virus type 1 J. Virol. 76 2002 8276 8284
    • (2002) J. Virol. , vol.76 , pp. 8276-8284
    • Tang, J.1    Tang, S.2    Lobashevsky, E.3    Myracle, A.D.4    Fideli, U.5    Aldrovandi, G.6    Allen, S.7    Musonda, R.8    Kaslow, R.A.9
  • 156
    • 73549092165 scopus 로고    scopus 로고
    • Entry inhibitors in the treatment of HIV-1 infection
    • J.C. Tilton, and R.W. Doms Entry inhibitors in the treatment of HIV-1 infection Antiviral Res. 85 2010 91 100
    • (2010) Antiviral Res. , vol.85 , pp. 91-100
    • Tilton, J.C.1    Doms, R.W.2
  • 157
    • 73549101090 scopus 로고    scopus 로고
    • Pharmacogenetics of antiretrovirals
    • V. Tozzi Pharmacogenetics of antiretrovirals Antiviral Res. 85 2010 190 200
    • (2010) Antiviral Res. , vol.85 , pp. 190-200
    • Tozzi, V.1
  • 160
    • 33748898695 scopus 로고    scopus 로고
    • APOBEC3G genetic variants and their association with risk of HIV infection in highly exposed Caucasians
    • H.S. Valcke, N.F. Bernard, J. Bruneau, M. Alary, C.M. Tsoukas, and M. Roger APOBEC3G genetic variants and their association with risk of HIV infection in highly exposed Caucasians AIDS 20 2006 1984 1986
    • (2006) AIDS , vol.20 , pp. 1984-1986
    • Valcke, H.S.1    Bernard, N.F.2    Bruneau, J.3    Alary, M.4    Tsoukas, C.M.5    Roger, M.6
  • 165
    • 35748948369 scopus 로고    scopus 로고
    • Elite control of HIV Infection: Implications for vaccines and treatment
    • B.D. Walker Elite control of HIV Infection: implications for vaccines and treatment Top HIV Med. 15 2007 134 136
    • (2007) Top HIV Med. , vol.15 , pp. 134-136
    • Walker, B.D.1
  • 168
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3000 shared controls
    • WTTC
    • WTTC Genome-wide association study of 14,000 cases of seven common diseases and 3000 shared controls Nature 447 2007 661 678
    • (2007) Nature , vol.447 , pp. 661-678
    • Wttc1
  • 169
    • 52249115840 scopus 로고    scopus 로고
    • Transcriptional profiles in CD8+ T cells from HIV+ progressors on HAART are characterized by coordinated up-regulation of oxidative phosphorylation enzymes and interferon responses
    • J.Q. Wu, D.E. Dwyer, W.B. Dyer, Y.H. Yang, B. Wang, and N.K. Saksena Transcriptional profiles in CD8+ T cells from HIV+ progressors on HAART are characterized by coordinated up-regulation of oxidative phosphorylation enzymes and interferon responses Virology 380 2008 124 135
    • (2008) Virology , vol.380 , pp. 124-135
    • Wu, J.Q.1    Dwyer, D.E.2    Dyer, W.B.3    Yang, Y.H.4    Wang, B.5    Saksena, N.K.6
  • 170
    • 79952702444 scopus 로고    scopus 로고
    • Genome-wide analysis of primary CD4+ and CD8+ T cell transcriptomes shows evidence for a network of enriched pathways associated with HIV disease
    • J.Q. Wu, D.E. Dwyer, W.B. Dyer, Y.H. Yang, B. Wang, and N.K. Saksena Genome-wide analysis of primary CD4+ and CD8+ T cell transcriptomes shows evidence for a network of enriched pathways associated with HIV disease Retrovirology 8 2011 18
    • (2011) Retrovirology , vol.8 , pp. 18
    • Wu, J.Q.1    Dwyer, D.E.2    Dyer, W.B.3    Yang, Y.H.4    Wang, B.5    Saksena, N.K.6
  • 171
    • 67749148923 scopus 로고    scopus 로고
    • A genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replication
    • M.L. Yeung, L. Houzet, V.S. Yedavalli, and K.T. Jeang A genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replication J. Biol. Chem. 284 2009 19463 19473
    • (2009) J. Biol. Chem. , vol.284 , pp. 19463-19473
    • Yeung, M.L.1    Houzet, L.2    Yedavalli, V.S.3    Jeang, K.T.4
  • 173
    • 84870408680 scopus 로고    scopus 로고
    • Evidence for selection at HIV host susceptibility genes in a West Central African human population
    • K. Zhao, Y. Ishida, T.K. Oleksyk, C.A. Winkler, and A.L. Roca Evidence for selection at HIV host susceptibility genes in a West Central African human population BMC Evol. Biol. 12 2012 237
    • (2012) BMC Evol. Biol. , vol.12 , pp. 237
    • Zhao, K.1    Ishida, Y.2    Oleksyk, T.K.3    Winkler, C.A.4    Roca, A.L.5


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