The HIV coreceptor switch: A population dynamical perspective

Trends in Microbiology

Volumn 13, Issue 6, 2005, Pages 269-277

  Regoes, Roland R ^a   Bonhoeffer, Sebastian ^b  

^a EMORY UNIVERSITY   (United States)

^b ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CELL INTERACTION; CELL POPULATION; DISEASE COURSE; GENE MUTATION; GENE SWITCHING; HUMAN IMMUNODEFICIENCY VIRUS; HYPOTHESIS; IMMUNE RESPONSE; IMMUNE SYSTEM; MICROBIAL POPULATION DYNAMICS; MOLECULAR EVOLUTION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVIEW; STOCHASTIC MODEL; TARGET CELL; VIRUS REPLICATION; VIRUS TRANSMISSION;

DISEASE PROGRESSION; EVOLUTION, MOLECULAR; HIV; HIV INFECTIONS; HUMANS; RECEPTORS, CCR5; RECEPTORS, CXCR4; SELECTION (GENETICS);

EID: 20344399376     PISSN: 0966842X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tim.2005.04.005     Document Type: Review

References (64)

1. E.A. Berger Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease Annu. Rev. Immunol. 17 1999 657 700
2. E.A. Berger A new classification for HIV-1 Nature 391 1998 240
3. A. Bjørndal Coreceptor usage of primary human immunodeficiency virus type 1 isolates varies according to biological phenotype J. Virol. 71 1997 7478 7487
4. A.B. van't Wout Macrophage-tropic variants initiate human- immunodeficiency-virus type-1 infection after sexual, parenteral, and vertical transmission J. Clin. Invest. 94 1994 2060 2067
5. J.P. Moore Co-receptors for HIV-1 entry Curr. Opin. Immunol. 9 1997 551 562
6. R. Liu Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection Cell 86 1996 367 377
7. D.A. Wilkinson A 32-bp deletion within the CCR5 locus protects against transmission of parenterally acquired human immunodeficiency virus but does not affect progression to AIDS-defining illness J. Infect. Dis. 178 1998 1163 1166
8. H. Sheppard HIV-1 infection in individuals with the CCR5-Delta32/Delta32 genotype: acquisition of syncytium-inducing virus at seroconversion J. Acquir. Immune Defic. Syndr. 29 2002 307 313
9. H. Schuitemaker Macrophage-tropic HIV variants - initiators of infection and AIDS pathogenesis J. Leukoc. Biol. 56 1994 218 224
10. E.L. Delwart Human immunodeficiency virus type 1 populations in blood and semen J. Virol. 72 1998 617 623
11. G. Meng Primary intestinal epithelial cells selectively transfer R5 HIV-1 to CCR5+ cells Nat. Med. 8 2002 150 156
12. A. Granelli-Piperno Immature dendritic cells selectively replicate macrophagetropic (M-tropic) human immunodeficiency virus type 1, while mature cells efficiently transmit both M- and T-tropic virus to T cells J. Virol. 72 1998 2733 2737
13. J.C. Reece HIV-1 selection by epidermal dendritic cells during transmission across human skin J. Exp. Med. 187 1998 1623 1631
14. W.W. Agace Constitutive expression of stromal derived factor-1 by mucosal epithelia and its role in HIV transmission and propagation Curr. Biol. 10 2000 325 328
15. A.G. Rodrigo Dynamics of syncytium-inducing and non-syncytium-inducing type 1 human immunodeficiency viruses during primary infection AIDS Res. Hum. Retroviruses 13 1997 1447 1451
16. M. Cornelissen Syncytium-inducing (SI) phenotype suppression at seroconversion after intramuscular inoculation of a non-syncytium-inducing/SI phenotypically mixed human immunodeficiency virus population J. Virol. 69 1995 1810 1818
17. R.D. Pratt Virological characterization of primary human- immunodeficiency- virus type-1 infection in a health-care worker following needlestick injury J. Infect. Dis. 172 1995 851 854
18. E.A. Berger Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease Annu. Rev. Immunol. 17 1999 657 700
19. R. Veazey, and A. Lackner The mucosal immune system and HIV-1 infection AIDS Rev. 5 2004 245 252
20. E.C. Holmes On the origin and evolution of the human immunodeficiency virus (HIV) Biol. Rev. Camb. Philos. Soc. 76 2001 239 254
21. A.S. Perelson Modelling viral and immune system dynamics Nat. Rev. Immunol. 2 2002 28 36
22. L.M. Mansky, and H.M. Temin Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase J. Virol. 69 1995 5087 5094
23. R.A. Fouchier Phenotype-associated sequence variation in the third variable domain of the human immunodeficiency virus type 1 gp120 molecule J. Virol. 66 1992 3183 3187
24. J.J. De Jong Minimal requirements for the human immunodeficiency virus type 1 V3 domain to support the syncytium-inducing phenotype: analysis by single amino acid substitution J. Virol. 66 1992 6777 6780
25. M.A. Jensen Improved coreceptor usage prediction and genotypic monitoring of R5-to-X4 transition by motif analysis of human immunodeficiency virus type 1 env V3 loop sequences J. Virol. 77 2003 13376 13388
26. C. Pastore Intrinsic obstacles to human immunodeficiency virus type 1 coreceptor switching J. Virol. 78 2004 7565 7574
27. M. Tersmette, and F. Miedema Interaction between HIV and the host immune system in the pathogenesis of AIDS AIDS 4 1990 S57 S66
28. F. Miedema AIDS pathogenesis: a dynamic interaction between HIV and the immune system Immunol. Today 11 1990 293 297
29. P.T.A. Schellekens Low T-cell responsiveness to activation via CD3/TCR is a prognostic marker for acquired-immunodeficiency-syndrome (AIDS) in human immunodeficiency virus-1 (HIV-1)-infected men J. Clin. Immunol. 10 1990 121 127
30. D. Wodarz, and M.A. Nowak The effect of different immune responses on the evolution of virulent CXCR4-tropic HIV Proc. R. Soc. Lond. B. Biol. Sci. 265 1998 2149 2158
31. D. Wodarz Dynamics of macrophage and T cell infection by HIV J. Theor. Biol. 196 1999 101 113
32. D.S. Callaway Virus phenotype switching and disease progression in HIV-1 infection Proc. R. Soc. Lond. B. Biol. Sci. 266 1999 2523 2530
33. S. Bonhoeffer Causes of HIV diversity Nature 376 1995 125
34. Y. Yamaguchi, and T. Gojobori Evolutionary mechanisms and population dynamics of the third variable envelope region of HIV within single hosts Proc. Natl. Acad. Sci. U. S. A. 94 1997 1264 1269
35. J.M. Harouse CD8+ T cell-mediated CXC chemokine receptor 4-simian/human immunodeficiency virus suppression in dually infected rhesus macaques Proc. Natl. Acad. Sci. U. S. A. 100 2003 10977 10982
36. D.C. Bou-Habib Cryptic nature of envelope V3 region epitopes protects primary monocytotropic human immunodeficiency virus type 1 from antibody neutralization J. Virol. 68 1994 6006 6013
37. A. Trkola Neutralization sensitivity of human immunodeficiency virus type 1 primary isolates to antibodies and CD4-based reagents is independent of coreceptor usage J. Virol. 72 1998 1876 1885
38. Z. Zhang Sexual transmission and propagation of SIV and HIV in resting and activated CD4(+) T cells Science 286 1999 1353 1357
39. B. Lee Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages Proc. Natl. Acad. Sci. U. S. A. 96 1999 5215 5220
40. C.C. Bleul The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes Proc. Natl. Acad. Sci. U. S. A. 94 1997 1925 1930
41. H. Blaak In vivo HIV-1 infection of CD45RA(+)CD4(+) T cells is established primarily by syncytium-inducing variants and correlates with the rate of CD4(+) T cell decline Proc. Natl. Acad. Sci. U. S. A. 97 2000 1269 1274
42. R.P. Van Rij Differential coreceptor expression allows for independent evolution of non-syncytium-inducing and syncytium-inducing HIV- 1 J. Clin. Invest. 106 2000 1039 1052
43. M. Roederer CD8 naive T cell counts decrease progressively in HIV-infected adults J. Clin. Invest. 95 1995 2061 2066
44. J.M. Benito Quantitative alterations of the functionally distinct subsets of CD4 and CD8 T lymphocytes in asymptomatic HIV infection: changes in the expression of CD45RO, CD45RA, CD11b, CD38, HLA-DR, and CD25 antigens J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. 14 1997 128 135
45. A.M. de Roda Husman CC chemokine receptor 5 cell-surface expression in relation to CC chemokine receptor 5 genotype and the clinical course of HIV-1 infection J. Immunol. 163 1999 4597 4603
46. M.D. Hazenberg T-cell division in human immunodeficiency virus (HIV)-1 infection is mainly due to immune activation: a longitudinal analysis in patients before and during highly active antiretroviral therapy (HAART) Blood 95 2000 249 255
47. P. Simmonds Determinants of HIV disease progression: six-year longitudinal study in the Edinburgh haemophilia/HIV cohort Lancet 338 1991 1159 1163
48. M.A. Ostrowski Expression of chemokine receptors CXCR4 and CCR5 in HIV-1- infected and uninfected individuals J. Immunol. 161 1998 3195 3201
49. M.P. Davenport Cell turnover and cell tropism in HIV-1 infection Trends Microbiol. 10 2002 275 278
50. R. Shankarappa Consistent viral evolutionary changes associated with the progression of human immunodeficiency virus type 1 infection J. Virol. 73 1999 10489 10502
51. R.G. Carroll Differential regulation of HIV-1 fusion cofactor expression by CD28 costimulation of CD4+ T cells Science 276 1997 273 276
52. A. Valentin Dual effect of interleukin 4 on HIV-1 expression: implications for viral phenotypic switch and disease progression Proc. Natl. Acad. Sci. U. S. A. 95 1998 8886 8891
53. S. Glushakova Infection of human tonsil histocultures: a model for HIV pathogenesis Nat. Med. 1 1995 1320 1322
54. M.L. Penn CXCR4 utilization is sufficient to trigger CD4+ T cell depletion in HIV-1-infected human lymphoid tissue Proc. Natl. Acad. Sci. U. S. A. 96 1999 663 668
55. G.R. Picchio The cell tropism of human immunodeficiency virus type 1 determines the kinetics of plasma viremia in SCID mice reconstituted with human peripheral blood leukocytes J. Virol. 72 1998 2002 2009
56. Y. Zhang Use of inhibitors to evaluate coreceptor usage by simian and simian/human immunodeficiency viruses and human immunodeficiency virus type 2 in primary cells J. Virol. 74 2000 6893 6910
57. M.B. Feinberg, and J.P. Moore AIDS vaccine models: challenging challenge viruses Nat. Med. 8 2002 207 210
58. J.M. Harouse Distinct pathogenic sequela in rhesus macaques infected with CCR5 or CXCR4 utilizing SHIVs Science 284 1999 816 819
59. J.F. Kreisberg Cytopathicity of human immunodeficiency virus type 1 primary isolates depends on coreceptor usage and not patient disease status J. Virol. 75 2001 8842 8847
60. J.C. Grivel, and L.B. Margolis CCR5- and CXCR4-tropic HIV-1 are equally cytopathic for their T-cell targets in human lymphoid tissue Nat. Med. 5 1999 344 346
61. R.A. Seder, and R. Ahmed Similarities and differences in CD4+ and CD8+ effector and memory T cell generation Nat. Immunol. 4 2003 835 842
62. A.T. Haase Quantitative image analysis of HIV-1 infection in lymphoid tissue Science 274 1996 985 989
63. M. Koot Prognostic value of HIV-1 syncytium-inducing phenotype for rate of CD4+ cell depletion and progression to AIDS Ann. Intern. Med. 118 1993 681 688
64. J.M. Brenchley T-cell subsets that harbor human immunodeficiency virus (HIV) in vivo: implications for HIV pathogenesis J. Virol. 78 2004 1160 1168