-
1
-
-
33645285267
-
Retroviral DNA integration: reaction pathway and critical intermediates
-
10.1038/sj.emboj.7601005, 1422164, 16482214
-
Li M, Mizuuchi M, Burke TR, Craigie R. Retroviral DNA integration: reaction pathway and critical intermediates. EMBO J 2006, 25:1295-1304. 10.1038/sj.emboj.7601005, 1422164, 16482214.
-
(2006)
EMBO J
, vol.25
, pp. 1295-1304
-
-
Li, M.1
Mizuuchi, M.2
Burke, T.R.3
Craigie, R.4
-
2
-
-
0034622521
-
Oligomeric states of the HIV-1 integrase as measured by time-resolved fluorescence anisotropy
-
10.1021/bi000397j, 10924120
-
Deprez E, Tauc P, Leh H, Mouscadet JF, Auclair C, Brochon JC. Oligomeric states of the HIV-1 integrase as measured by time-resolved fluorescence anisotropy. Biochemistry 2000, 39:9275-9284. 10.1021/bi000397j, 10924120.
-
(2000)
Biochemistry
, vol.39
, pp. 9275-9284
-
-
Deprez, E.1
Tauc, P.2
Leh, H.3
Mouscadet, J.F.4
Auclair, C.5
Brochon, J.C.6
-
3
-
-
14244264128
-
HIV-1 integrase crosslinked oligomers are active in vitro
-
10.1093/nar/gki241, 549407, 15718297
-
Faure A, Calmels C, Desjobert C, Castroviejo M, Caumont-Sarcos A, Tarrago-Litvak L, Litvak S, Parissi V. HIV-1 integrase crosslinked oligomers are active in vitro. Nucleic Acids Res 2005, 33:977-986. 10.1093/nar/gki241, 549407, 15718297.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 977-986
-
-
Faure, A.1
Calmels, C.2
Desjobert, C.3
Castroviejo, M.4
Caumont-Sarcos, A.5
Tarrago-Litvak, L.6
Litvak, S.7
Parissi, V.8
-
4
-
-
34347226332
-
Inhibiting HIV-1 integrase by shifting its oligomerization equilibrium
-
10.1073/pnas.0700781104, 1895947, 17488811
-
Hayouka Z, Rosenbluh J, Levin A, Loya S, Lebendiker M, Veprintsev D, Kotler M, Hizi A, Loyter A, Friedler A. Inhibiting HIV-1 integrase by shifting its oligomerization equilibrium. Proc Natl Acad Sci USA 2007, 104:8316-8321. 10.1073/pnas.0700781104, 1895947, 17488811.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 8316-8321
-
-
Hayouka, Z.1
Rosenbluh, J.2
Levin, A.3
Loya, S.4
Lebendiker, M.5
Veprintsev, D.6
Kotler, M.7
Hizi, A.8
Loyter, A.9
Friedler, A.10
-
5
-
-
0346036088
-
HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells
-
Cherepanov P, Maertens G, Proost P, Devreese B, Van Beeumen J, Engelborghs Y, De Clercq E, Debyser Z. HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells. J Biol Chem 2003, 278:372-381.
-
(2003)
J Biol Chem
, vol.278
, pp. 372-381
-
-
Cherepanov, P.1
Maertens, G.2
Proost, P.3
Devreese, B.4
Van Beeumen, J.5
Engelborghs, Y.6
De Clercq, E.7
Debyser, Z.8
-
6
-
-
0041856142
-
LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells
-
10.1074/jbc.M303594200, 12796494
-
Maertens G, Cherepanov P, Pluymers W, Busschots K, De Clercq E, Debyser Z, Engelborghs Y. LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells. J Biol Chem 2003, 278:33528-33539. 10.1074/jbc.M303594200, 12796494.
-
(2003)
J Biol Chem
, vol.278
, pp. 33528-33539
-
-
Maertens, G.1
Cherepanov, P.2
Pluymers, W.3
Busschots, K.4
De Clercq, E.5
Debyser, Z.6
Engelborghs, Y.7
-
7
-
-
79960377787
-
In vitro DNA tethering of HIV-1 integrase by the transcriptional coactivator LEDGF/p75
-
10.1016/j.jmb.2011.03.073, 21763490
-
McNeely M, Hendrix J, Busschots K, Boons E, Deleersnijder A, Gerard M, Christ F, Debyser Z. In vitro DNA tethering of HIV-1 integrase by the transcriptional coactivator LEDGF/p75. J Mol Biol 2011, 410:811-830. 10.1016/j.jmb.2011.03.073, 21763490.
-
(2011)
J Mol Biol
, vol.410
, pp. 811-830
-
-
McNeely, M.1
Hendrix, J.2
Busschots, K.3
Boons, E.4
Deleersnijder, A.5
Gerard, M.6
Christ, F.7
Debyser, Z.8
-
8
-
-
84861483595
-
LEDGF/p75-Independent HIV-1 Replication Demonstrates a Role for HRP-2 and Remains Sensitive to Inhibition by LEDGINs
-
10.1371/journal.ppat.1002558, 3291655, 22396646
-
Schrijvers R, De Rijck J, Demeulemeester J, Adachi N, Vets S, Ronen K, Christ F, Bushman FD, Debyser Z, Gijsbers R. LEDGF/p75-Independent HIV-1 Replication Demonstrates a Role for HRP-2 and Remains Sensitive to Inhibition by LEDGINs. PLoS Pathog 2012, 8:e1002558. 10.1371/journal.ppat.1002558, 3291655, 22396646.
-
(2012)
PLoS Pathog
, vol.8
-
-
Schrijvers, R.1
De Rijck, J.2
Demeulemeester, J.3
Adachi, N.4
Vets, S.5
Ronen, K.6
Christ, F.7
Bushman, F.D.8
Debyser, Z.9
Gijsbers, R.10
-
9
-
-
33750358735
-
An essential role for LEDGF/p75 in HIV integration
-
10.1126/science.1132319, 16959972
-
Llano M, Saenz DT, Meehan A, Wongthida P, Peretz M, Walker WH, Teo W, Poeschla EM. An essential role for LEDGF/p75 in HIV integration. Science 2006, 314:461-464. 10.1126/science.1132319, 16959972.
-
(2006)
Science
, vol.314
, pp. 461-464
-
-
Llano, M.1
Saenz, D.T.2
Meehan, A.3
Wongthida, P.4
Peretz, M.5
Walker, W.H.6
Teo, W.7
Poeschla, E.M.8
-
10
-
-
28644443483
-
A role for LEDGF/p75 in targeting HIV DNA integration
-
10.1038/nm1329, 16311605
-
Ciuffi A, Llano M, Poeschla E, Hoffmann C, Leipzig J, Shinn P, Ecker JR, Bushman F. A role for LEDGF/p75 in targeting HIV DNA integration. Nat Med 2005, 11:1287-1289. 10.1038/nm1329, 16311605.
-
(2005)
Nat Med
, vol.11
, pp. 1287-1289
-
-
Ciuffi, A.1
Llano, M.2
Poeschla, E.3
Hoffmann, C.4
Leipzig, J.5
Shinn, P.6
Ecker, J.R.7
Bushman, F.8
-
11
-
-
84859641222
-
Novel therapeutic strategies targeting HIV integrase
-
10.1186/1741-7015-10-34, 3348091, 22498430
-
Quashie PK, Sloan RD, Wainberg MA. Novel therapeutic strategies targeting HIV integrase. BMC Med 2012, 10:34. 10.1186/1741-7015-10-34, 3348091, 22498430.
-
(2012)
BMC Med
, vol.10
, pp. 34
-
-
Quashie, P.K.1
Sloan, R.D.2
Wainberg, M.A.3
-
12
-
-
77952553431
-
Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication
-
10.1038/nchembio.370, 20473303
-
Christ F, Voet A, Marchand A, Nicolet S, Desimmie BA, Marchand D, Bardiot D, Van der Veken NJ, Van Remoortel B, Strelkov SV. Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication. Nat Chem Biol 2010, 6:442-448. 10.1038/nchembio.370, 20473303.
-
(2010)
Nat Chem Biol
, vol.6
, pp. 442-448
-
-
Christ, F.1
Voet, A.2
Marchand, A.3
Nicolet, S.4
Desimmie, B.A.5
Marchand, D.6
Bardiot, D.7
Van der Veken, N.J.8
Van Remoortel, B.9
Strelkov, S.V.10
-
13
-
-
84870670336
-
The LEDGF/p75 integrase interaction, a novel target for anti-HIV therapy
-
10.1016/j.virol.2012.09.033, 23217620
-
Christ F, Debyser Z. The LEDGF/p75 integrase interaction, a novel target for anti-HIV therapy. Virology 2013, 435:102-109. 10.1016/j.virol.2012.09.033, 23217620.
-
(2013)
Virology
, vol.435
, pp. 102-109
-
-
Christ, F.1
Debyser, Z.2
-
14
-
-
84860871902
-
Multimode, cooperative mechanism of action of allosteric HIV-1 integrase inhibitors
-
10.1074/jbc.M112.354373, 3351293, 22437836
-
Kessl JJ, Jena N, Koh Y, Taskent-Sezgin H, Slaughter A, Feng L, de Silva S, Wu L, Le Grice SF, Engelman A. Multimode, cooperative mechanism of action of allosteric HIV-1 integrase inhibitors. J Biol Chem 2012, 287:16801-16811. 10.1074/jbc.M112.354373, 3351293, 22437836.
-
(2012)
J Biol Chem
, vol.287
, pp. 16801-16811
-
-
Kessl, J.J.1
Jena, N.2
Koh, Y.3
Taskent-Sezgin, H.4
Slaughter, A.5
Feng, L.6
de Silva, S.7
Wu, L.8
Le Grice, S.F.9
Engelman, A.10
-
15
-
-
79251545504
-
Allosteric inhibitor development targeting HIV-1 integrase
-
10.1002/cmdc.201000443, 3115487, 21275045
-
Al-Mawsawi LQ, Neamati N. Allosteric inhibitor development targeting HIV-1 integrase. ChemMedChem 2011, 6:228-241. 10.1002/cmdc.201000443, 3115487, 21275045.
-
(2011)
ChemMedChem
, vol.6
, pp. 228-241
-
-
Al-Mawsawi, L.Q.1
Neamati, N.2
-
16
-
-
84864387134
-
Small-Molecule Inhibitors of the LEDGF/p75 Binding Site of Integrase Block HIV Replication and Modulate Integrase Multimerization
-
10.1128/AAC.00717-12, 3421592, 22664975
-
Christ F, Shaw S, Demeulemeester J, Desimmie BA, Marchand A, Butler S, Smets W, Chaltin P, Westby M, Debyser Z, Pickford C. Small-Molecule Inhibitors of the LEDGF/p75 Binding Site of Integrase Block HIV Replication and Modulate Integrase Multimerization. Antimicrob Agents Chemother 2012, 56:4365-4374. 10.1128/AAC.00717-12, 3421592, 22664975.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 4365-4374
-
-
Christ, F.1
Shaw, S.2
Demeulemeester, J.3
Desimmie, B.A.4
Marchand, A.5
Butler, S.6
Smets, W.7
Chaltin, P.8
Westby, M.9
Debyser, Z.10
Pickford, C.11
-
17
-
-
84862271587
-
New Class of HIV-1 Integrase (IN) Inhibitors with a Dual Mode of Action
-
10.1074/jbc.M112.347534, 22535962
-
Tsiang M, Jones GS, Niedziela-Majka A, Kan E, Lansdon EB, Huang W, Hung M, Samuel D, Novikov N, Xu Y. New Class of HIV-1 Integrase (IN) Inhibitors with a Dual Mode of Action. J Biol Chem 2012, 287:21189-21203. 10.1074/jbc.M112.347534, 22535962.
-
(2012)
J Biol Chem
, vol.287
, pp. 21189-21203
-
-
Tsiang, M.1
Jones, G.S.2
Niedziela-Majka, A.3
Kan, E.4
Lansdon, E.B.5
Huang, W.6
Hung, M.7
Samuel, D.8
Novikov, N.9
Xu, Y.10
-
18
-
-
0035025888
-
A quantitative assay for HIV DNA integration in vivo
-
10.1038/87979, 11329067
-
Butler SL, Hansen MS, Bushman FD. A quantitative assay for HIV DNA integration in vivo. Nat Med 2001, 7:631-634. 10.1038/87979, 11329067.
-
(2001)
Nat Med
, vol.7
, pp. 631-634
-
-
Butler, S.L.1
Hansen, M.S.2
Bushman, F.D.3
-
19
-
-
79955570502
-
-
: World Intellectual Property Organization, WO/2005/028669, Van Acker K, Lodewij k, August, BUNKENS L, Elisabeth, Louis, DAMS G, Karel, Julia, HERTOGS K, IVENS T, Pauline, Eduard, NIJS E, Jos, Amandus
-
Van Acker K, Lodewij K, Van Acker K, Lodewij k, August, BUNKENS L, Elisabeth, Louis, DAMS G, Karel, Julia, HERTOGS K, IVENS T, Pauline, Eduard, NIJS E, Jos, Amandus Time-of-addition assay for identifying anti-viral compounds 2005, : World Intellectual Property Organization, WO/2005/028669, Van Acker K, Lodewij k, August, BUNKENS L, Elisabeth, Louis, DAMS G, Karel, Julia, HERTOGS K, IVENS T, Pauline, Eduard, NIJS E, Jos, Amandus.
-
(2005)
Time-of-addition assay for identifying anti-viral compounds
-
-
Van Acker, K.1
Lodewij, K.2
-
20
-
-
0034723439
-
Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells
-
10.1126/science.287.5453.646, 10649997
-
Hazuda DJ, Felock P, Witmer M, Wolfe A, Stillmock K, Grobler JA, Espeseth A, Gabryelski L, Schleif W, Blau C, Miller MD. Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells. Science 2000, 287:646-650. 10.1126/science.287.5453.646, 10649997.
-
(2000)
Science
, vol.287
, pp. 646-650
-
-
Hazuda, D.J.1
Felock, P.2
Witmer, M.3
Wolfe, A.4
Stillmock, K.5
Grobler, J.A.6
Espeseth, A.7
Gabryelski, L.8
Schleif, W.9
Blau, C.10
Miller, M.D.11
-
21
-
-
0024347717
-
Temporal aspects of DNA and RNA synthesis during human immunodeficiency virus infection: evidence for differential gene expression
-
250962, 2760980
-
Kim SY, Byrn R, Groopman J, Baltimore D. Temporal aspects of DNA and RNA synthesis during human immunodeficiency virus infection: evidence for differential gene expression. J Virol 1989, 63:3708-3713. 250962, 2760980.
-
(1989)
J Virol
, vol.63
, pp. 3708-3713
-
-
Kim, S.Y.1
Byrn, R.2
Groopman, J.3
Baltimore, D.4
-
22
-
-
80054990193
-
Timing of the components of the HIV life cycle in productively infected CD4+ T cells in a population of HIV-infected individuals
-
10.1128/JVI.05095-11, 3187481, 21835801
-
Murray JM, Kelleher AD, Cooper DA. Timing of the components of the HIV life cycle in productively infected CD4+ T cells in a population of HIV-infected individuals. J Virol 2011, 85:10798-10805. 10.1128/JVI.05095-11, 3187481, 21835801.
-
(2011)
J Virol
, vol.85
, pp. 10798-10805
-
-
Murray, J.M.1
Kelleher, A.D.2
Cooper, D.A.3
-
23
-
-
84865375176
-
HIV-1 Antiretroviral Drug Therapy
-
10.1101/cshperspect.a007161, 3312400, 22474613
-
Arts EJ, Hazuda DJ. HIV-1 Antiretroviral Drug Therapy. Cold Spring Harbor perspectives in medicine 2012, 2:a007161. 10.1101/cshperspect.a007161, 3312400, 22474613.
-
(2012)
Cold Spring Harbor perspectives in medicine
, vol.2
-
-
Arts, E.J.1
Hazuda, D.J.2
-
24
-
-
57649116079
-
Residues in the HIV-1 capsid assembly inhibitor binding site are essential for maintaining the assembly-competent quaternary structure of the capsid protein
-
10.1074/jbc.M804230200, 18772135
-
Bartonova V, Igonet S, Sticht J, Glass B, Habermann A, Vaney MC, Sehr P, Lewis J, Rey FA, Krausslich HG. Residues in the HIV-1 capsid assembly inhibitor binding site are essential for maintaining the assembly-competent quaternary structure of the capsid protein. J Biol Chem 2008, 283:32024-32033. 10.1074/jbc.M804230200, 18772135.
-
(2008)
J Biol Chem
, vol.283
, pp. 32024-32033
-
-
Bartonova, V.1
Igonet, S.2
Sticht, J.3
Glass, B.4
Habermann, A.5
Vaney, M.C.6
Sehr, P.7
Lewis, J.8
Rey, F.A.9
Krausslich, H.G.10
-
25
-
-
49649105669
-
Transportin-SR2 imports HIV into the nucleus
-
10.1016/j.cub.2008.07.079, 18722123
-
Christ F, Thys W, De Rijck J, Gijsbers R, Albanese A, Arosio D, Emiliani S, Rain JC, Benarous R, Cereseto A, Debyser Z. Transportin-SR2 imports HIV into the nucleus. Current biology: CB 2008, 18:1192-1202. 10.1016/j.cub.2008.07.079, 18722123.
-
(2008)
Current biology: CB
, vol.18
, pp. 1192-1202
-
-
Christ, F.1
Thys, W.2
De Rijck, J.3
Gijsbers, R.4
Albanese, A.5
Arosio, D.6
Emiliani, S.7
Rain, J.C.8
Benarous, R.9
Cereseto, A.10
Debyser, Z.11
-
26
-
-
6344219975
-
Evaluation of the functional involvement of human immunodeficiency virus type 1 integrase in nuclear import of viral cDNA during acute infection
-
10.1128/JVI.78.21.11563-11573.2004, 523288, 15479797
-
Ikeda T, Nishitsuji H, Zhou X, Nara N, Ohashi T, Kannagi M, Masuda T. Evaluation of the functional involvement of human immunodeficiency virus type 1 integrase in nuclear import of viral cDNA during acute infection. J Virol 2004, 78:11563-11573. 10.1128/JVI.78.21.11563-11573.2004, 523288, 15479797.
-
(2004)
J Virol
, vol.78
, pp. 11563-11573
-
-
Ikeda, T.1
Nishitsuji, H.2
Zhou, X.3
Nara, N.4
Ohashi, T.5
Kannagi, M.6
Masuda, T.7
-
27
-
-
48749128360
-
HIV-1 pre-integration complexes selectively target d econdensed chromatin in the nuclear periphery.
-
10.1371/journal.pone.0002413, 2398779, 18545681
-
Albanese A, Arosio D, Terreni M, Cereseto A. HIV-1 pre-integration complexes selectively target d econdensed chromatin in the nuclear periphery. PLoS One 2008, 3:e2413. 10.1371/journal.pone.0002413, 2398779, 18545681.
-
(2008)
PLoS One
, vol.3
-
-
Albanese, A.1
Arosio, D.2
Terreni, M.3
Cereseto, A.4
-
28
-
-
84859850227
-
Development of an AlphaScreen-based HIV-1 integrase dimerization assay for discovery of novel allosteric inhibitors
-
10.1177/1087057111436343, 22337657
-
Demeulemeester J, Tintori C, Botta M, Debyser Z, Christ F. Development of an AlphaScreen-based HIV-1 integrase dimerization assay for discovery of novel allosteric inhibitors. J Biomol Screen 2012, 17:618-628. 10.1177/1087057111436343, 22337657.
-
(2012)
J Biomol Screen
, vol.17
, pp. 618-628
-
-
Demeulemeester, J.1
Tintori, C.2
Botta, M.3
Debyser, Z.4
Christ, F.5
-
29
-
-
84869081642
-
Phage display-directed discovery of LEDGF/p75 binding cyclic peptide inhibitors of HIV replication
-
Desimmie BA, Humbert M, Lescrinier E, Hendrix J, Vets S, Gijsbers R, Ruprecht RM, Dietrich U, Debyser Z, Christ F. Phage display-directed discovery of LEDGF/p75 binding cyclic peptide inhibitors of HIV replication. Molecular therapy: the journal of the American Society of Gene Therapy 2012, 20:2064-2075.
-
(2012)
Molecular therapy: the journal of the American Society of Gene Therapy
, vol.20
, pp. 2064-2075
-
-
Desimmie, B.A.1
Humbert, M.2
Lescrinier, E.3
Hendrix, J.4
Vets, S.5
Gijsbers, R.6
Ruprecht, R.M.7
Dietrich, U.8
Debyser, Z.9
Christ, F.10
-
30
-
-
0028924020
-
Human immunodeficiency virus type 1 integrase: effects of mutations on viral ability to integrate, direct viral gene expression from unintegrated viral DNA templates, and sustain viral propagation in primary cells
-
188585, 7983732
-
Wiskerchen M, Muesing MA. Human immunodeficiency virus type 1 integrase: effects of mutations on viral ability to integrate, direct viral gene expression from unintegrated viral DNA templates, and sustain viral propagation in primary cells. J Virol 1995, 69:376-386. 188585, 7983732.
-
(1995)
J Virol
, vol.69
, pp. 376-386
-
-
Wiskerchen, M.1
Muesing, M.A.2
-
31
-
-
84878652014
-
Non-Catalytic Site Integrase Inhibitors Target the Integrase Domain during Virus Production and Induce a Reverse Transcription Block
-
Yant S, Tsai L, O'Sullivan C, Cihlar T, Balakrishnan M. Non-Catalytic Site Integrase Inhibitors Target the Integrase Domain during Virus Production and Induce a Reverse Transcription Block. 2013, http://www.retroconference.org/2013b/Abstracts/46625.htm.
-
(2013)
-
-
Yant, S.1
Tsai, L.2
O'Sullivan, C.3
Cihlar, T.4
Balakrishnan, M.5
-
32
-
-
0028915128
-
Multiple effects of mutations in human immunodeficiency virus type 1 integrase on viral replication
-
188965, 7535863
-
Engelman A, Englund G, Orenstein JM, Martin MA, Craigie R. Multiple effects of mutations in human immunodeficiency virus type 1 integrase on viral replication. J Virol 1995, 69:2729-2736. 188965, 7535863.
-
(1995)
J Virol
, vol.69
, pp. 2729-2736
-
-
Engelman, A.1
Englund, G.2
Orenstein, J.M.3
Martin, M.A.4
Craigie, R.5
-
33
-
-
79952588405
-
LEDGF dominant interference proteins demonstrate prenuclear exposure of HIV-1 integrase and synergize with LEDGF depletion to destroy viral infectivity
-
10.1128/JVI.01295-10, 3067863, 21270171
-
Meehan AM, Saenz DT, Morrison J, Hu C, Peretz M, Poeschla EM. LEDGF dominant interference proteins demonstrate prenuclear exposure of HIV-1 integrase and synergize with LEDGF depletion to destroy viral infectivity. J Virol 2011, 85:3570-3583. 10.1128/JVI.01295-10, 3067863, 21270171.
-
(2011)
J Virol
, vol.85
, pp. 3570-3583
-
-
Meehan, A.M.1
Saenz, D.T.2
Morrison, J.3
Hu, C.4
Peretz, M.5
Poeschla, E.M.6
-
34
-
-
11244255412
-
Lens epithelium-derived growth factor/p75 prevents proteasomal degradation of HIV-1 integrase
-
10.1074/jbc.M408508200, 15475359
-
Llano M, Delgado S, Vanegas M, Poeschla EM. Lens epithelium-derived growth factor/p75 prevents proteasomal degradation of HIV-1 integrase. J Biol Chem 2004, 279:55570-55577. 10.1074/jbc.M408508200, 15475359.
-
(2004)
J Biol Chem
, vol.279
, pp. 55570-55577
-
-
Llano, M.1
Delgado, S.2
Vanegas, M.3
Poeschla, E.M.4
-
35
-
-
84873019961
-
Identification of low molecular weight nuclear complexes containing integrase during the early stages of HIV-1 infection
-
10.1186/1742-4690-10-13, 3571920, 23369367
-
Gerard A, Soler N, Segeral E, Belshan M, Emiliani S. Identification of low molecular weight nuclear complexes containing integrase during the early stages of HIV-1 infection. Retrovirology 2013, 10:13. 10.1186/1742-4690-10-13, 3571920, 23369367.
-
(2013)
Retrovirology
, vol.10
, pp. 13
-
-
Gerard, A.1
Soler, N.2
Segeral, E.3
Belshan, M.4
Emiliani, S.5
-
36
-
-
79960373686
-
A critical subset model provides a conceptual basis for the high antiviral activity of major HIV drugs
-
Shen L, Rabi SA, Sedaghat AR, Shan L, Lai J, Xing S, Siliciano RF. A critical subset model provides a conceptual basis for the high antiviral activity of major HIV drugs. Sci Transl Med 2011, 3:63-91.
-
(2011)
Sci Transl Med
, vol.3
, pp. 63-91
-
-
Shen, L.1
Rabi, S.A.2
Sedaghat, A.R.3
Shan, L.4
Lai, J.5
Xing, S.6
Siliciano, R.F.7
-
37
-
-
46049096485
-
Dose-response curve slope sets class-specific limits on inhibitory potential of anti-HIV drugs
-
10.1038/nm1777, 2743464, 18552857
-
Shen L, Peterson S, Sedaghat AR, McMahon MA, Callender M, Zhang H, Zhou Y, Pitt E, Anderson KS, Acosta EP, Siliciano RF. Dose-response curve slope sets class-specific limits on inhibitory potential of anti-HIV drugs. Nat Med 2008, 14:762-766. 10.1038/nm1777, 2743464, 18552857.
-
(2008)
Nat Med
, vol.14
, pp. 762-766
-
-
Shen, L.1
Peterson, S.2
Sedaghat, A.R.3
McMahon, M.A.4
Callender, M.5
Zhang, H.6
Zhou, Y.7
Pitt, E.8
Anderson, K.S.9
Acosta, E.P.10
Siliciano, R.F.11
-
38
-
-
33751433927
-
Potent nonnucleoside reverse transcriptase inhibitors target HIV-1 Gag-Pol
-
10.1371/journal.ppat.0020119, 1635531, 17096588
-
Figueiredo A, Moore KL, Mak J, Sluis-Cremer N, de Bethune MP, Tachedjian G. Potent nonnucleoside reverse transcriptase inhibitors target HIV-1 Gag-Pol. PLoS Pathog 2006, 2:e119. 10.1371/journal.ppat.0020119, 1635531, 17096588.
-
(2006)
PLoS Pathog
, vol.2
-
-
Figueiredo, A.1
Moore, K.L.2
Mak, J.3
Sluis-Cremer, N.4
de Bethune, M.P.5
Tachedjian, G.6
-
39
-
-
70350366737
-
HIV-1 Gag processing intermediates trans-dominantly interfere with HIV-1 infectivity
-
10.1074/jbc.M109.027144, 2785601, 19666477
-
Muller B, Anders M, Akiyama H, Welsch S, Glass B, Nikovics K, Clavel F, Tervo HM, Keppler OT, Krausslich HG. HIV-1 Gag processing intermediates trans-dominantly interfere with HIV-1 infectivity. J Biol Chem 2009, 284:29692-29703. 10.1074/jbc.M109.027144, 2785601, 19666477.
-
(2009)
J Biol Chem
, vol.284
, pp. 29692-29703
-
-
Muller, B.1
Anders, M.2
Akiyama, H.3
Welsch, S.4
Glass, B.5
Nikovics, K.6
Clavel, F.7
Tervo, H.M.8
Keppler, O.T.9
Krausslich, H.G.10
-
40
-
-
84864392088
-
Saquinavir inhibits early events associated with establishment of HIV-1 infection: potential role for protease inhibitors in prevention
-
10.1128/AAC.00399-12, 3421585, 22664974
-
Stefanidou M, Herrera C, Armanasco N, Shattock RJ. Saquinavir inhibits early events associated with establishment of HIV-1 infection: potential role for protease inhibitors in prevention. Antimicrob Agents Chemother 2012, 56:4381-4390. 10.1128/AAC.00399-12, 3421585, 22664974.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 4381-4390
-
-
Stefanidou, M.1
Herrera, C.2
Armanasco, N.3
Shattock, R.J.4
-
41
-
-
33846049539
-
Identification of the LEDGF/p75 binding site in HIV-1 integrase
-
10.1016/j.jmb.2006.10.094, 17137594
-
Busschots K, Voet A, De Maeyer M, Rain JC, Emiliani S, Benarous R, Desender L, Debyser Z, Christ F. Identification of the LEDGF/p75 binding site in HIV-1 integrase. J Mol Biol 2007, 365:1480-1492. 10.1016/j.jmb.2006.10.094, 17137594.
-
(2007)
J Mol Biol
, vol.365
, pp. 1480-1492
-
-
Busschots, K.1
Voet, A.2
De Maeyer, M.3
Rain, J.C.4
Emiliani, S.5
Benarous, R.6
Desender, L.7
Debyser, Z.8
Christ, F.9
-
42
-
-
27644457706
-
Upscaling of lentiviral vector production by tangential flow filtration
-
10.1002/jgm.778, 15906396
-
Geraerts M, Michiels M, Baekelandt V, Debyser Z, Gijsbers R. Upscaling of lentiviral vector production by tangential flow filtration. J Gene Med 2005, 7:1299-1310. 10.1002/jgm.778, 15906396.
-
(2005)
J Gene Med
, vol.7
, pp. 1299-1310
-
-
Geraerts, M.1
Michiels, M.2
Baekelandt, V.3
Debyser, Z.4
Gijsbers, R.5
-
43
-
-
0037384693
-
Impact of the central polypurine tract on the kinetics of human immunodeficiency virus type 1 vector transduction
-
10.1128/JVI.77.8.4685-4694.2003, 152151, 12663775
-
Van Maele B, De Rijck J, De Clercq E, Debyser Z. Impact of the central polypurine tract on the kinetics of human immunodeficiency virus type 1 vector transduction. J Virol 2003, 77:4685-4694. 10.1128/JVI.77.8.4685-4694.2003, 152151, 12663775.
-
(2003)
J Virol
, vol.77
, pp. 4685-4694
-
-
Van Maele, B.1
De Rijck, J.2
De Clercq, E.3
Debyser, Z.4
-
44
-
-
0034694017
-
Rev-independent expression of synthetic gag-pol genes of human immunodeficiency virus type 1 and simian immunodeficiency virus: implications for the safety of lentiviral vectors
-
10.1089/104303400750038507, 11096444
-
Wagner R, Graf M, Bieler K, Wolf H, Grunwald T, Foley P, Uberla K. Rev-independent expression of synthetic gag-pol genes of human immunodeficiency virus type 1 and simian immunodeficiency virus: implications for the safety of lentiviral vectors. Hum Gene Ther 2000, 11:2403-2413. 10.1089/104303400750038507, 11096444.
-
(2000)
Hum Gene Ther
, vol.11
, pp. 2403-2413
-
-
Wagner, R.1
Graf, M.2
Bieler, K.3
Wolf, H.4
Grunwald, T.5
Foley, P.6
Uberla, K.7
-
45
-
-
16544395270
-
Site-directed, Ligase-Independent Mutagenesis (SLIM): a single-tube methodology approaching 100% efficiency in 4 h
-
10.1093/nar/gnh172, 535700, 15585660
-
Chiu J, March PE, Lee R, Tillett D. Site-directed, Ligase-Independent Mutagenesis (SLIM): a single-tube methodology approaching 100% efficiency in 4 h. Nucleic Acids Res 2004, 32:e174. 10.1093/nar/gnh172, 535700, 15585660.
-
(2004)
Nucleic Acids Res
, vol.32
-
-
Chiu, J.1
March, P.E.2
Lee, R.3
Tillett, D.4
-
46
-
-
23044514646
-
Construction of a set Gateway-based destination vectors for high-throughput cloning and expression screening in Escherichia coli
-
10.1016/j.ab.2005.05.015, 15993367
-
Busso D, Delagoutte-Busso B, Moras D. Construction of a set Gateway-based destination vectors for high-throughput cloning and expression screening in Escherichia coli. Anal Biochem 2005, 343:313-321. 10.1016/j.ab.2005.05.015, 15993367.
-
(2005)
Anal Biochem
, vol.343
, pp. 313-321
-
-
Busso, D.1
Delagoutte-Busso, B.2
Moras, D.3
|