Differential prevalence of the HLA-C -35 CC genotype among viremic long term non-progressor and elite controller HIV+ individuals

Immunobiology

Volumn 217, Issue 9, 2012, Pages 889-894

  Ballana, Ester ^a   Ruiz de Andres, Alba ^a   Mothe, Beatriz ^a   Ramirez de Arellano, Eva ^b   Aguilar, Francisco ^b   Badia, Roger ^a   Grau, Eulalia ^a   Clotet, Bonaventura ^a   del Val, Margarita ^b,c   Brander, Christian ^a,d   Esté, José A ^a  

^a HOSPITAL UNIVERSITARI GERMANS TRIAS I PUJOL   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

^d INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

Author keywords

Elite controller; Genotype; HIV; HLA C; Long term non progressor

Indexed keywords

ANTIRETROVIRUS AGENT; CYTOSINE; HLA C ANTIGEN; THYMINE;

ARTICLE; CONTROLLED STUDY; DISEASE COURSE; GENE FREQUENCY; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; LONG TERM NON PROGRESSOR; MAJOR CLINICAL STUDY; PHENOTYPE; POPULATION RESEARCH; PREVALENCE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; VIRAL GENETICS; VIREMIA; VIRUS LOAD;

ALLELES; GENOTYPE; HIV INFECTIONS; HIV LONG-TERM SURVIVORS; HLA-C ANTIGENS; HUMANS; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; VIREMIA;

EID: 84864323575     PISSN: 01712985     EISSN: 18783279     Source Type: Journal    
DOI: 10.1016/j.imbio.2011.12.012     Document Type: Article

References (29)

1. An P., Winkler C.A. Host genes associated with HIV/AIDS: advances in gene discovery. Trends Genet. 2010, 26:119-131.
2. Ballana E., Pauls E., Senserrich J., Clotet B., Perron-Sierra F., Tucker G.C., Este J.A. Cell adhesion through alphaV-containing integrins is required for efficient HIV-1 infection in macrophages. Blood 2009, 113:1278-1286.
3. Ballana E., Senserrich J., Pauls E., Faner R., Mercader J.M., Uyttebroeck F., Palou E., Mena M.P., Grau E., Clotet B., Ruiz L., Telenti A., Ciuffi A., Este J.A. ZNRD1 (zinc ribbon domain-containing 1) is a host cellular factor that influences HIV-1 replication and disease progression. Clin. Infect. Dis. 2010, 50:1022-1032.
4. Blackwell J.M., Jamieson S.E., Burgner D. HLA and infectious diseases. Clin. Microbiol. Rev. 2009, 22:370-385. (Table of contents).
5. Blankson J.N. Effector mechanisms in HIV-1 infected elite controllers: highly active immune responses?. Antiviral Res. 2010, 85:295-302.
6. Bushman F.D., Malani N., Fernandes J., D'Orso I., Cagney G., Diamond T.L., Zhou H., Hazuda D.J., Espeseth A.S., Konig R., Bandyopadhyay S., Ideker T., Goff S.P., Krogan N.J., Frankel A.D., Young J.A., Chanda S.K. Host cell factors in HIV replication: meta-analysis of genome-wide studies. PLoS Pathog. 2009, 5:e1000437.
7. Casado C., Colombo S., Rauch A., Martinez R., Gunthard H.F., Garcia S., Rodriguez C., Del Romero J., Telenti A., Lopez-Galindez C. Host and viral genetic correlates of clinical definitions of HIV-1 disease progression. PLoS One 2010, 5:e11079.
8. Catano G., Kulkarni H., He W., Marconi V.C., Agan B.K., Landrum M., Anderson S., Delmar J., Telles V., Song L., Castiblanco J., Clark R.A., Dolan M.J., Ahuja S.K. HIV-1 disease-influencing effects associated with ZNRD1, HCP5 and HLA-C alleles are attributable mainly to either HLA-A10 or HLA-B*57 alleles. PLoS One 2008, 3:e3636.
9. Corrah T.W., Goonetilleke N., Kopycinski J., Deeks S.G., Cohen M.S., Borrow P., McMichael A., Brackenridge S. Reappraisal of the relationship between the HIV-1-protective single-nucleotide polymorphism 35 kilobases upstream of the HLA-C gene and surface HLA-C expression. J. Virol. 2011, 85:3367-3374.
10. Emu B., Sinclair E., Hatano H., Ferre A., Shacklett B., Martin J.N., McCune J.M., Deeks S.G. HLA class I-restricted T-cell responses may contribute to the control of human immunodeficiency virus infection, but such responses are not always necessary for long-term virus control. J. Virol. 2008, 82:5398-5407.
11. Fellay J., Ge D., Shianna K.V., Colombo S., Ledergerber B., Cirulli E.T., Urban T.J., Zhang K., Gumbs C.E., Smith J.P., Castagna A., Cozzi-Lepri A., De Luca A., Easterbrook P., Gunthard H.F., Mallal S., Mussini C., Dalmau J., Martinez-Picado J., Miro J.M., Obel N., Wolinsky S.M., Martinson J.J., Detels R., Margolick J.B., Jacobson L.P., Descombes P., Antonarakis S.E., Beckmann J.S., O'Brien S.J., Letvin N.L., McMichael A.J., Haynes B.F., Carrington M., Feng S., Telenti A., Goldstein D.B. Common genetic variation and the control of HIV-1 in humans. PLoS Genet. 2009, 5:e1000791.
12. Fellay J., Shianna K.V., Ge D., Colombo S., Ledergerber B., Weale M., Zhang K., Gumbs C., Castagna A., Cossarizza A., Cozzi-Lepri A., De Luca A., Easterbrook P., Francioli P., Mallal S., Martinez-Picado J., Miro J.M., Obel N., Smith J.P., Wyniger J., Descombes P., Antonarakis S.E., Letvin N.L., McMichael A.J., Haynes B.F., Telenti A., Goldstein D.B. A whole-genome association study of major determinants for host control of HIV-1. Science 2007, 317:944-947.
13. Frahm N., Korber B.T., Adams C.M., Szinger J.J., Draenert R., Addo M.M., Feeney M.E., Yusim K., Sango K., Brown N.V., SenGupta D., Piechocka-Trocha A., Simonis T., Marincola F.M., Wurcel A.G., Stone D.R., Russell C.J., Adolf P., Cohen D., Roach T., StJohn A., Khatri A., Davis K., Mullins J., Goulder P.J., Walker B.D., Brander C. Consistent cytotoxic-T-lymphocyte targeting of immunodominant regions in human immunodeficiency virus across multiple ethnicities. J. Virol. 2004, 78:2187-2200.
14. Garcia-Merino I., de Las Cuevas N., Jimenez J.L., Gallego J., Gomez C., Prieto C., Serramia M.J., Lorente R., Munoz-Fernandez M.A. The Spanish HIV BioBank: a model of cooperative HIV research. Retrovirology 2009, 6:27.
15. Goulder P.J., Watkins D.I. Impact of MHC class I diversity on immune control of immunodeficiency virus replication. Nat. Rev. Immunol. 2008, 8:619-630.
16. Greene W.C., Debyser Z., Ikeda Y., Freed E.O., Stephens E., Yonemoto W., Buckheit R.W., Este J.A., Cihlar T. Novel targets for HIV therapy. Antiviral Res. 2008, 80:251-265.
17. International-HIV-Controllers-Study The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. Science 2010, 330:1551-1557.
18. Kaur G., Mehra N. Genetic determinants of HIV-1 infection and progression to AIDS: immune response genes. Tissue Antigens 2009, 74:373-385.
19. Kulkarni S., Savan R., Qi Y., Gao X., Yuki Y., Bass S.E., Martin M.P., Hunt P., Deeks S.G., Telenti A., Pereyra F., Goldstein D., Wolinsky S., Walker B., Young H.A., Carrington M. Differential microRNA regulation of HLA-C expression and its association with HIV control. Nature 2011, 472:495-498.
20. Leslie A., Matthews P.C., Listgarten J., Carlson J.M., Kadie C., Ndung'u T., Brander C., Coovadia H., Walker B.D., Heckerman D., Goulder P.J. Additive contribution of HLA class I alleles in the immune control of HIV-1 infection. J. Virol. 2010, 84:9879-9888.
21. Limou S., Le Clerc S., Coulonges C., Carpentier W., Dina C., Delaneau O., Labib T., Taing L., Sladek R., Deveau C., Ratsimandresy R., Montes M., Spadoni J.L., Lelievre J.D., Levy Y., Therwath A., Schachter F., Matsuda F., Gut I., Froguel P., Delfraissy J.F., Hercberg S., Zagury J.F. Genomewide association study of an AIDS-nonprogression cohort emphasizes the role played by HLA genes (ANRS Genomewide Association Study 02). J. Infect. Dis. 2009, 199:419-426.
22. Llano, A., Frahm, N., Brander, C., 2009. How to Optimally Define Optimal Cytotoxic T∼Lymphocyte Epitopes in HIV Infection? Los Alamos HIV database, pp. 1-23.
23. Martin M.P., Nelson G., Lee J.H., Pellett F., Gao X., Wade J., Wilson M.J., Trowsdale J., Gladman D., Carrington M. Cutting edge: susceptibility to psoriatic arthritis: influence of activating killer Ig-like receptor genes in the absence of specific HLA-C alleles. J. Immunol. 2002, 169:2818-2822.
24. Salgado M., Simon A., Sanz-Minguela B., Rallon N.I., Lopez M., Vicario J.L., Benito J.M., Rodes B. An additive effect of protective host genetic factors correlates with HIV nonprogression status. J. Acquir. Immune Defic. Syndr. 2011, 56:300-305.
25. Specht A., Telenti A., Martinez R., Fellay J., Bailes E., Evans D.T., Carrington M., Hahn B.H., Goldstein D.B., Kirchhoff F. Counteraction of HLA-C-mediated immune control of HIV-1 by Nef. J. Virol. 2010.
26. Stranger B.E., Nica A.C., Forrest M.S., Dimas A., Bird C.P., Beazley C., Ingle C.E., Dunning M., Flicek P., Koller D., Montgomery S., Tavare S., Deloukas P., Dermitzakis E.T. Population genomics of human gene expression. Nat. Genet. 2007, 39:1217-1224.
27. Telenti A., Goldstein D.B. Genomics meets HIV-1. Nat. Rev. Microbiol. 2006, 4:865-873.
28. Tozzi V. Pharmacogenetics of antiretrovirals. Antiviral Res. 2010, 85:190-200.
29. van Manen D., Kootstra N.A., Boeser-Nunnink B., Handulle M.A., van't Wout A.B., Schuitemaker H. Association of HLA-C and HCP5 gene regions with the clinical course of HIV-1 infection. AIDS 2009, 23:19-28.