DEFB1 gene polymorphisms and increased risk of HIV-1 infection in Brazilian children

AIDS

Volumn 20, Issue 12, 2006, Pages 1673-1675

  Milanese, Michele ^a   Segat, Ludovica ^a   Pontillo, Alessandra ^a   Arraes, Luiz Claudio ^b,c   De Lima Filho, José Luiz ^c   Crovella, Sergio ^a,c  

^a UNIVERSITY OF TRIESTE   (Italy)

^b INSTITUTO DE MEDICINA INTEGRAL PROF FERNANDO FIGUEIRA   (Brazil)

^c FEDERAL UNIVERSITY OF PERNAMBUCO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

DEFB1 PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

5' UNTRANSLATED REGION; ADOLESCENT; ARTICLE; BRAZIL; CHILD; CONTROLLED STUDY; DISEASE MARKER; GENETIC POLYMORPHISM; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; NONHUMAN; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ADOLESCENT; ANTI-INFECTIVE AGENTS; BETA-DEFENSINS; BRAZIL; CHILD; CHILD, PRESCHOOL; GENE FREQUENCY; GENETIC MARKERS; GENOTYPE; HIV INFECTIONS; HIV-1; HUMANS; INFANT; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS;

EID: 33746768204     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.aids.0000238417.05819.40     Document Type: Article

References (8)

1. Kagan BL, Ganz T, Lehrer RI. Defensins: a family of antimicrobial and cytotoxic peptides. Toxicology 1994; 87:131-149.
2. Quiñones-Mateu ME, Lederman MM, Feng Z, Chakraborty B, Weber J, Rangel HR, et al. Human epithelial beta-defensins 2 and 3 inhibit HIV-1 replication. AIDS 2003; 17:F39-F48.
3. Leikina E, Delanoe-Ayari H, Melikov K, Cho MS, Chen A, Waring AJ, et al. Carbohydrate-binding molecules inhibit viral fusion and entry by crosslinking membrane glycoproteins. Nat Immunol 2005; 6:995-1001.
4. Sun L, Finnegan CM, Kish-Catalone T, Blumenthal R, Garzino-Demo P, La Terra Maggiore GM, et al. Human beta-defensins suppress human immunodeficiency virus infection: potential role in mucosal protection. J Virol 2005; 79:14318-14329.
5. Braida L, Boniotto M, Pontillo A, Tovo PA, Amoroso A, Crovella S. A single-nucleotide polymorphism in the human beta-defensin 1 gene is associated with HIV-1 infection in Italian children. AIDS 2004; 18:1598-1600.
6. Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc 1995; 57:289-300.
7. Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005; 21:263-265.
8. Jurevic RJ, Chrisman P, Mancl L, Livingston R, Dale BA. Single-nucleotide polymorphisms and haplotype analysis in beta-defensin genes in different ethnic populations. Genet Test 2002; 6:261-269.