-
1
-
-
77950343791
-
Pattern recognition receptors and inflammation
-
O. Takeuchi, and S. Akira Pattern recognition receptors and inflammation Cell 140 2010 805 820
-
(2010)
Cell
, vol.140
, pp. 805-820
-
-
Takeuchi, O.1
Akira, S.2
-
2
-
-
79956314622
-
Immune signaling by RIG-I-like receptors
-
Y.M. Loo, and M. Gale Jr. Immune signaling by RIG-I-like receptors Immunity 34 2011 680 692
-
(2011)
Immunity
, vol.34
, pp. 680-692
-
-
Loo, Y.M.1
Gale Jr., M.2
-
3
-
-
79961133270
-
MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response
-
F. Hou, L. Sun, H. Zheng, B. Skaug, Q.X. Jiang, and Z.J. Chen MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response Cell 146 2011 448 461
-
(2011)
Cell
, vol.146
, pp. 448-461
-
-
Hou, F.1
Sun, L.2
Zheng, H.3
Skaug, B.4
Jiang, Q.X.5
Chen, Z.J.6
-
4
-
-
79956300649
-
Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
-
T. Kawai, and S. Akira Toll-like receptors and their crosstalk with other innate receptors in infection and immunity Immunity 34 2011 637 650
-
(2011)
Immunity
, vol.34
, pp. 637-650
-
-
Kawai, T.1
Akira, S.2
-
5
-
-
84855918194
-
Regulation of RLR-mediated innate immune signaling - It is all about keeping the balance
-
K. Eisenacher, and A. Krug Regulation of RLR-mediated innate immune signaling - it is all about keeping the balance Eur J Cell Biol 91 2012 36 47
-
(2012)
Eur J Cell Biol
, vol.91
, pp. 36-47
-
-
Eisenacher, K.1
Krug, A.2
-
6
-
-
80755126865
-
Mapping a dynamic innate immunity protein interaction network regulating type i interferon production
-
S. Li, L. Wang, M. Berman, Y.Y. Kong, and M.E. Dorf Mapping a dynamic innate immunity protein interaction network regulating type I interferon production Immunity 35 2011 426 440
-
(2011)
Immunity
, vol.35
, pp. 426-440
-
-
Li, S.1
Wang, L.2
Berman, M.3
Kong, Y.Y.4
Dorf, M.E.5
-
7
-
-
79955509835
-
Direct effects of type i interferons on cells of the immune system
-
S. Hervas-Stubbs, J.L. Perez-Gracia, A. Rouzaut, M.F. Sanmamed, A. Le Bon, and I. Melero Direct effects of type I interferons on cells of the immune system Clin Cancer Res 17 2011 2619 2627
-
(2011)
Clin Cancer Res
, vol.17
, pp. 2619-2627
-
-
Hervas-Stubbs, S.1
Perez-Gracia, J.L.2
Rouzaut, A.3
Sanmamed, M.F.4
Le Bon, A.5
Melero, I.6
-
8
-
-
84862794613
-
The yin and yang of viruses and interferons
-
B.X. Wang, and E.N. Fish The yin and yang of viruses and interferons Trends Immunol 33 2012 190 197
-
(2012)
Trends Immunol
, vol.33
, pp. 190-197
-
-
Wang, B.X.1
Fish, E.N.2
-
9
-
-
70350490572
-
Dynamic accumulation of plasmacytoid dendritic cells in lymph nodes is regulated by interferon-beta
-
Y. Gao, B. Majchrzak-Kita, E.N. Fish, and J.L. Gommerman Dynamic accumulation of plasmacytoid dendritic cells in lymph nodes is regulated by interferon-beta Blood 114 2009 2623 2631
-
(2009)
Blood
, vol.114
, pp. 2623-2631
-
-
Gao, Y.1
Majchrzak-Kita, B.2
Fish, E.N.3
Gommerman, J.L.4
-
10
-
-
84862855875
-
Nucleic acid sensing at the interface between innate and adaptive immunity in vaccination
-
C.J. Desmet, and K.J. Ishii Nucleic acid sensing at the interface between innate and adaptive immunity in vaccination Nat Rev Immunol 12 2012 479 491
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 479-491
-
-
Desmet, C.J.1
Ishii, K.J.2
-
11
-
-
80052143412
-
RIG-I-like receptors: Cytoplasmic sensors for non-self RNA
-
H. Kato, K. Takahasi, and T. Fujita RIG-I-like receptors: cytoplasmic sensors for non-self RNA Immunol Rev 243 2011 91 98
-
(2011)
Immunol Rev
, vol.243
, pp. 91-98
-
-
Kato, H.1
Takahasi, K.2
Fujita, T.3
-
12
-
-
79952186298
-
MicroRNAs: The fine-tuners of Toll-like receptor signalling
-
L.A. O'Neill, F.J. Sheedy, and C.E. McCoy MicroRNAs: the fine-tuners of Toll-like receptor signalling Nat Rev Immunol 11 2011 163 175
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 163-175
-
-
O'Neill, L.A.1
Sheedy, F.J.2
McCoy, C.E.3
-
13
-
-
84865298775
-
Dissecting negative regulation of Toll-like receptor signaling
-
T. Kondo, T. Kawai, and S. Akira Dissecting negative regulation of Toll-like receptor signaling Trends Immunol 2012
-
(2012)
Trends Immunol
-
-
Kondo, T.1
Kawai, T.2
Akira, S.3
-
14
-
-
79959649316
-
RIG-I like receptors and their signaling crosstalk in the regulation of antiviral immunity
-
H.J. Ramos, and M. Gale Jr. RIG-I like receptors and their signaling crosstalk in the regulation of antiviral immunity Curr Opin Virol 1 2011 167 176
-
(2011)
Curr Opin Virol
, vol.1
, pp. 167-176
-
-
Ramos, H.J.1
Gale Jr., M.2
-
15
-
-
46349085629
-
Interferon alfacon 1 inhibits SARS-CoV infection in human bronchial epithelial Calu-3 cells
-
Y. Kumaki, C.W. Day, M.K. Wandersee, B.P. Schow, J.S. Madsen, D. Grant, J.P. Roth, D.F. Smee, L.M. Blatt, and D.L. Barnard Interferon alfacon 1 inhibits SARS-CoV infection in human bronchial epithelial Calu-3 cells Biochem Biophys Res Commun 371 2008 110 113
-
(2008)
Biochem Biophys Res Commun
, vol.371
, pp. 110-113
-
-
Kumaki, Y.1
Day, C.W.2
Wandersee, M.K.3
Schow, B.P.4
Madsen, J.S.5
Grant, D.6
Roth, J.P.7
Smee, D.F.8
Blatt, L.M.9
Barnard, D.L.10
-
16
-
-
77953025376
-
A randomized controlled trial of low-dose recombinant human interferons alpha-2b nasal spray to prevent acute viral respiratory infections in military recruits
-
L. Gao, S. Yu, Q. Chen, Z. Duan, J. Zhou, C. Mao, D. Yu, W. Zhu, J. Nie, and Y. Hou A randomized controlled trial of low-dose recombinant human interferons alpha-2b nasal spray to prevent acute viral respiratory infections in military recruits Vaccine 28 2010 4445 4451
-
(2010)
Vaccine
, vol.28
, pp. 4445-4451
-
-
Gao, L.1
Yu, S.2
Chen, Q.3
Duan, Z.4
Zhou, J.5
Mao, C.6
Yu, D.7
Zhu, W.8
Nie, J.9
Hou, Y.10
-
17
-
-
15044352317
-
Use of interferon-alpha in patients with West Nile encephalitis: Report of 2 cases
-
A.C. Kalil, M.P. Devetten, S. Singh, B. Lesiak, D.P. Poage, K. Bargenquast, P. Fayad, and A.G. Freifeld Use of interferon-alpha in patients with West Nile encephalitis: report of 2 cases Clin Infect Dis 40 2005 764 766
-
(2005)
Clin Infect Dis
, vol.40
, pp. 764-766
-
-
Kalil, A.C.1
Devetten, M.P.2
Singh, S.3
Lesiak, B.4
Poage, D.P.5
Bargenquast, K.6
Fayad, P.7
Freifeld, A.G.8
-
18
-
-
79955546684
-
Treatment of yellow fever virus with an adenovirus-vectored interferon DEF201, in a hamster model
-
J.G. Julander, J. Ennis, J. Turner, and J.D. Morrey Treatment of yellow fever virus with an adenovirus-vectored interferon DEF201, in a hamster model Antimicrob Agents Chemother 55 2011 2067 2073
-
(2011)
Antimicrob Agents Chemother
, vol.55
, pp. 2067-2073
-
-
Julander, J.G.1
Ennis, J.2
Turner, J.3
Morrey, J.D.4
-
19
-
-
0033066490
-
Evaluation of immune globulin and recombinant interferon-alpha2b for treatment of experimental Ebola virus infections
-
P.B. Jahrling, T.W. Geisbert, J.B. Geisbert, J.R. Swearengen, M. Bray, N.K. Jaax, J.W. Huggins, J.W. LeDuc, and C.J. Peters Evaluation of immune globulin and recombinant interferon-alpha2b for treatment of experimental Ebola virus infections J Infect Dis 179 Suppl. 1 1999 S224 S234
-
(1999)
J Infect Dis
, vol.179
, Issue.SUPPL. 1
-
-
Jahrling, P.B.1
Geisbert, T.W.2
Geisbert, J.B.3
Swearengen, J.R.4
Bray, M.5
Jaax, N.K.6
Huggins, J.W.7
Leduc, J.W.8
Peters, C.J.9
-
20
-
-
78649319383
-
Comparative efficacy and overall safety of different doses of consensus interferon for treatment of chronic HCV infection: A systematic review and meta-analysis
-
S.M. Alavian, B. Behnava, and S.V. Tabatabaei Comparative efficacy and overall safety of different doses of consensus interferon for treatment of chronic HCV infection: a systematic review and meta-analysis Eur J Clin Pharmacol 66 2010 1071 1079
-
(2010)
Eur J Clin Pharmacol
, vol.66
, pp. 1071-1079
-
-
Alavian, S.M.1
Behnava, B.2
Tabatabaei, S.V.3
-
21
-
-
77956710095
-
Albinterferon-alpha 2b: A new treatment option for hepatitis C
-
R. Flisiak, and I. Flisiak Albinterferon-alpha 2b: a new treatment option for hepatitis C Expert Opin Biol Ther 10 2010 1509 1515
-
(2010)
Expert Opin Biol Ther
, vol.10
, pp. 1509-1515
-
-
Flisiak, R.1
Flisiak, I.2
-
22
-
-
84875006879
-
Clinical trial of the efficacy, dosing, safety and tolerability of Y-shaped pegylated interferon (YPEG-IFNα-2a) plus ribavirin in egyptian patients with untreated chronic hepatitis C
-
San Francisco, CA
-
Ashour MKF: Clinical trial of the efficacy, dosing, safety and tolerability of Y-shaped pegylated interferon (YPEG-IFNα-2a) plus ribavirin in egyptian patients with untreated chronic hepatitis C. In American Association for the study of liver diseases. San Francisco, CA; 2011.
-
(2011)
American Association for the Study of Liver Diseases
-
-
Ashour, M.K.F.1
-
23
-
-
70349292099
-
Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance
-
D. Ge, J. Fellay, A.J. Thompson, J.S. Simon, K.V. Shianna, T.J. Urban, E.L. Heinzen, P. Qiu, A.H. Bertelsen, and A.J. Muir Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance Nature 461 2009 399 401
-
(2009)
Nature
, vol.461
, pp. 399-401
-
-
Ge, D.1
Fellay, J.2
Thompson, A.J.3
Simon, J.S.4
Shianna, K.V.5
Urban, T.J.6
Heinzen, E.L.7
Qiu, P.8
Bertelsen, A.H.9
Muir, A.J.10
-
24
-
-
70349966196
-
Genetic variation in IL28B and spontaneous clearance of hepatitis C virus
-
D.L. Thomas, C.L. Thio, M.P. Martin, Y. Qi, D. Ge, C. O'Huigin, J. Kidd, K. Kidd, S.I. Khakoo, and G. Alexander Genetic variation in IL28B and spontaneous clearance of hepatitis C virus Nature 461 2009 798 801
-
(2009)
Nature
, vol.461
, pp. 798-801
-
-
Thomas, D.L.1
Thio, C.L.2
Martin, M.P.3
Qi, Y.4
Ge, D.5
O'Huigin, C.6
Kidd, J.7
Kidd, K.8
Khakoo, S.I.9
Alexander, G.10
-
25
-
-
77955873433
-
Phase 1b study of pegylated interferon lambda 1 with or without ribavirin in patients with chronic genotype 1 hepatitis C virus infection
-
A.J. Muir, M.L. Shiffman, A. Zaman, B. Yoffe, A. de la Torre, S. Flamm, S.C. Gordon, P. Marotta, J.M. Vierling, and J.C. Lopez-Talavera Phase 1b study of pegylated interferon lambda 1 with or without ribavirin in patients with chronic genotype 1 hepatitis C virus infection Hepatology 52 2010 822 832
-
(2010)
Hepatology
, vol.52
, pp. 822-832
-
-
Muir, A.J.1
Shiffman, M.L.2
Zaman, A.3
Yoffe, B.4
De La Torre, A.5
Flamm, S.6
Gordon, S.C.7
Marotta, P.8
Vierling, J.M.9
Lopez-Talavera, J.C.10
-
26
-
-
77955880854
-
Interferon-lambda: A new addition to an old family
-
R.P. Donnelly, and S.V. Kotenko Interferon-lambda: a new addition to an old family J Interferon Cytokine Res 30 2010 555 564
-
(2010)
J Interferon Cytokine Res
, vol.30
, pp. 555-564
-
-
Donnelly, R.P.1
Kotenko, S.V.2
-
27
-
-
80051814602
-
Targeting of Toll-like receptors: A decade of progress in combating infectious diseases
-
M. Hedayat, M.G. Netea, and N. Rezaei Targeting of Toll-like receptors: a decade of progress in combating infectious diseases Lancet Infect Dis 11 2011 702 712
-
(2011)
Lancet Infect Dis
, vol.11
, pp. 702-712
-
-
Hedayat, M.1
Netea, M.G.2
Rezaei, N.3
-
28
-
-
35048865713
-
Topical imiquimod: A review of its use in the management of anogenital warts, actinic keratoses, basal cell carcinoma and other skin lesions
-
A.J. Wagstaff, and C.M. Perry Topical imiquimod: a review of its use in the management of anogenital warts, actinic keratoses, basal cell carcinoma and other skin lesions Drugs 67 2007 2187 2210
-
(2007)
Drugs
, vol.67
, pp. 2187-2210
-
-
Wagstaff, A.J.1
Perry, C.M.2
-
29
-
-
34347399259
-
Oral resiquimod in chronic HCV infection: Safety and efficacy in 2 placebo-controlled, double-blind phase IIa studies
-
P.J. Pockros, D. Guyader, H. Patton, M.J. Tong, T. Wright, J.G. McHutchison, and T.C. Meng Oral resiquimod in chronic HCV infection: safety and efficacy in 2 placebo-controlled, double-blind phase IIa studies J Hepatol 47 2007 174 182
-
(2007)
J Hepatol
, vol.47
, pp. 174-182
-
-
Pockros, P.J.1
Guyader, D.2
Patton, H.3
Tong, M.J.4
Wright, T.5
McHutchison, J.G.6
Meng, T.C.7
-
30
-
-
67650526658
-
Current and future treatment options for HCV
-
B. Kronenberger, and S. Zeuzem Current and future treatment options for HCV Ann Hepatol 8 2009 103 112
-
(2009)
Ann Hepatol
, vol.8
, pp. 103-112
-
-
Kronenberger, B.1
Zeuzem, S.2
-
31
-
-
79960554471
-
Randomised clinical trial: Anti-viral activity of ANA773, an oral inducer of endogenous interferons acting via TLR7, in chronic HCV
-
J.F. Bergmann, J. de Bruijne, D.M. Hotho, R.J. de Knegt, A. Boonstra, C.J. Weegink, A.A. van Vliet, J. van de Wetering, S.P. Fletcher, and L.A. Bauman Randomised clinical trial: anti-viral activity of ANA773, an oral inducer of endogenous interferons acting via TLR7, in chronic HCV Aliment Pharmacol Ther 34 2011 443 453
-
(2011)
Aliment Pharmacol Ther
, vol.34
, pp. 443-453
-
-
Bergmann, J.F.1
De Bruijne, J.2
Hotho, D.M.3
De Knegt, R.J.4
Boonstra, A.5
Weegink, C.J.6
Van Vliet, A.A.7
Van De Wetering, J.8
Fletcher, S.P.9
Bauman, L.A.10
-
32
-
-
34547789747
-
Safety, pharmacokinetics and immune effects in normal volunteers of CPG 10101 (ACTILON), an investigational synthetic toll-like receptor 9 agonist
-
A.P. Vicari, T. Schmalbach, J. Lekstrom-Himes, M.L. Morris, M.J. Al-Adhami, C. Laframboise, P. Leese, A.M. Krieg, S.M. Efler, and H.L. Davis Safety, pharmacokinetics and immune effects in normal volunteers of CPG 10101 (ACTILON), an investigational synthetic toll-like receptor 9 agonist Antivir Ther 12 2007 741 751
-
(2007)
Antivir Ther
, vol.12
, pp. 741-751
-
-
Vicari, A.P.1
Schmalbach, T.2
Lekstrom-Himes, J.3
Morris, M.L.4
Al-Adhami, M.J.5
Laframboise, C.6
Leese, P.7
Krieg, A.M.8
Efler, S.M.9
Davis, H.L.10
-
33
-
-
84867403007
-
A phase 1, multi-center, randomized, placebo-controlled, dose-escalation study of IMO-2125, a TLR9 agonist, in hepatitis C nonresponders
-
Vienna, Austria
-
A. Muir, R. Ghalib, E. Lawitz, K. Patel, M. Rodriguez-torres, A. Sheikh, S. Sapp, R. Taylor, A. Bexon, and T. Sullivan A phase 1, multi-center, randomized, placebo-controlled, dose-escalation study of IMO-2125, a TLR9 agonist, in hepatitis C nonresponders EASL 45th Annual Meeting April Vienna, Austria 2010
-
(2010)
EASL 45th Annual Meeting April
-
-
Muir, A.1
Ghalib, R.2
Lawitz, E.3
Patel, K.4
Rodriguez-Torres, M.5
Sheikh, A.6
Sapp, S.7
Taylor, R.8
Bexon, A.9
Sullivan, T.10
-
35
-
-
84875004018
-
IMO-2125 plus ribavirin gives substantial first-dose viral load reductions, cumulative antiviral effect, is well tolerated in naïve genotype 1 HCV patients: A phase 1 trial
-
Berlin, Germany
-
D. Guyader, P. Bogomolov, Z. Kobalava, V. Moiseev, J. Szlavik, B. Astruc, I. Varkonyi, T. Sullivan, K. Horgan, and A. Bexon IMO-2125 plus ribavirin gives substantial first-dose viral load reductions, cumulative antiviral effect, is well tolerated in naïve genotype 1 HCV patients: a phase 1 trial EASL 46th Annual Meeting March Berlin, Germany 2011
-
(2011)
EASL 46th Annual Meeting March
-
-
Guyader, D.1
Bogomolov, P.2
Kobalava, Z.3
Moiseev, V.4
Szlavik, J.5
Astruc, B.6
Varkonyi, I.7
Sullivan, T.8
Horgan, K.9
Bexon, A.10
-
36
-
-
34250854079
-
The vaccine adjuvant monophosphoryl lipid A as a TRIF-biased agonist of TLR4
-
V. Mata-Haro, C. Cekic, M. Martin, P.M. Chilton, C.R. Casella, and T.C. Mitchell The vaccine adjuvant monophosphoryl lipid A as a TRIF-biased agonist of TLR4 Science 316 2007 1628 1632
-
(2007)
Science
, vol.316
, pp. 1628-1632
-
-
Mata-Haro, V.1
Cekic, C.2
Martin, M.3
Chilton, P.M.4
Casella, C.R.5
Mitchell, T.C.6
-
37
-
-
33845905223
-
Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling
-
A.L. Gavin, K. Hoebe, B. Duong, T. Ota, C. Martin, B. Beutler, and D. Nemazee Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling Science 314 2006 1936 1938
-
(2006)
Science
, vol.314
, pp. 1936-1938
-
-
Gavin, A.L.1
Hoebe, K.2
Duong, B.3
Ota, T.4
Martin, C.5
Beutler, B.6
Nemazee, D.7
-
39
-
-
34247234090
-
New hepatitis B vaccine formulated with an improved adjuvant system
-
M. Kundi New hepatitis B vaccine formulated with an improved adjuvant system Expert Rev Vaccines 6 2007 133 140
-
(2007)
Expert Rev Vaccines
, vol.6
, pp. 133-140
-
-
Kundi, M.1
-
40
-
-
77949889253
-
Clinical update of the AS04-adjuvanted human papillomavirus-16/18 cervical cancer vaccine, Cervarix
-
T.F. Schwarz Clinical update of the AS04-adjuvanted human papillomavirus-16/18 cervical cancer vaccine, Cervarix Adv Ther 26 2009 983 998
-
(2009)
Adv Ther
, vol.26
, pp. 983-998
-
-
Schwarz, T.F.1
-
41
-
-
77249176352
-
AS04, an aluminum salt- and TLR4 agonist-based adjuvant system, induces a transient localized innate immune response leading to enhanced adaptive immunity
-
A.M. Didierlaurent, S. Morel, L. Lockman, S.L. Giannini, M. Bisteau, H. Carlsen, A. Kielland, O. Vosters, N. Vanderheyde, and F. Schiavetti AS04, an aluminum salt- and TLR4 agonist-based adjuvant system, induces a transient localized innate immune response leading to enhanced adaptive immunity J Immunol 183 2009 6186 6197
-
(2009)
J Immunol
, vol.183
, pp. 6186-6197
-
-
Didierlaurent, A.M.1
Morel, S.2
Lockman, L.3
Giannini, S.L.4
Bisteau, M.5
Carlsen, H.6
Kielland, A.7
Vosters, O.8
Vanderheyde, N.9
Schiavetti, F.10
-
42
-
-
63849177560
-
Vaccine adjuvants: Scientific challenges and strategic initiatives
-
A.M. Harandi, G. Davies, and O.F. Olesen Vaccine adjuvants: scientific challenges and strategic initiatives Expert Rev Vaccines 8 2009 293 298
-
(2009)
Expert Rev Vaccines
, vol.8
, pp. 293-298
-
-
Harandi, A.M.1
Davies, G.2
Olesen, O.F.3
-
43
-
-
78650827526
-
Immunopotentiation of trivalent influenza vaccine when given with VAX102, a recombinant influenza M2e vaccine fused to the TLR5 ligand flagellin
-
H.K. Talbot, M.T. Rock, C. Johnson, L. Tussey, U. Kavita, A. Shanker, A.R. Shaw, and D.N. Taylor Immunopotentiation of trivalent influenza vaccine when given with VAX102, a recombinant influenza M2e vaccine fused to the TLR5 ligand flagellin PLoS ONE 5 2010 e14442
-
(2010)
PLoS ONE
, vol.5
, pp. 14442
-
-
Talbot, H.K.1
Rock, M.T.2
Johnson, C.3
Tussey, L.4
Kavita, U.5
Shanker, A.6
Shaw, A.R.7
Taylor, D.N.8
-
44
-
-
84864945063
-
Development of VAX128, a recombinant hemagglutinin (HA) influenza-flagellin fusion vaccine with improved safety and immune response
-
D.N. Taylor, J.J. Treanor, E.A. Sheldon, C. Johnson, S. Umlauf, L. Song, U. Kavita, G. Liu, L. Tussey, and K. Ozer Development of VAX128, a recombinant hemagglutinin (HA) influenza-flagellin fusion vaccine with improved safety and immune response Vaccine 2012
-
(2012)
Vaccine
-
-
Taylor, D.N.1
Treanor, J.J.2
Sheldon, E.A.3
Johnson, C.4
Umlauf, S.5
Song, L.6
Kavita, U.7
Liu, G.8
Tussey, L.9
Ozer, K.10
-
45
-
-
78649741148
-
Safety and immunogenicity of a recombinant hemagglutinin influenza-flagellin fusion vaccine (VAX125) in healthy young adults
-
J.J. Treanor, D.N. Taylor, L. Tussey, C. Hay, C. Nolan, T. Fitzgerald, G. Liu, U. Kavita, L. Song, and I. Dark Safety and immunogenicity of a recombinant hemagglutinin influenza-flagellin fusion vaccine (VAX125) in healthy young adults Vaccine 28 2010 8268 8274
-
(2010)
Vaccine
, vol.28
, pp. 8268-8274
-
-
Treanor, J.J.1
Taylor, D.N.2
Tussey, L.3
Hay, C.4
Nolan, C.5
Fitzgerald, T.6
Liu, G.7
Kavita, U.8
Song, L.9
Dark, I.10
-
46
-
-
84904236282
-
Targeted impairment of innate antiviral responses in the liver of chronic hepatitis C patients
-
L. Jouan, L. Chatel-Chaix, P. Melancon, I.G. Rodrigue-Gervais, V.A. Raymond, S. Selliah, M. Bilodeau, N. Grandvaux, and D. Lamarre Targeted impairment of innate antiviral responses in the liver of chronic hepatitis C patients J Hepatol 2011
-
(2011)
J Hepatol
-
-
Jouan, L.1
Chatel-Chaix, L.2
Melancon, P.3
Rodrigue-Gervais, I.G.4
Raymond, V.A.5
Selliah, S.6
Bilodeau, M.7
Grandvaux, N.8
Lamarre, D.9
-
47
-
-
75549086227
-
Distinct antiviral signaling pathways in primary human hepatocytes and their differential disruption by HCV NS3 protease
-
L. Jouan, P. Melancon, I.G. Rodrigue-Gervais, V.A. Raymond, S. Selliah, G. Boucher, M. Bilodeau, N. Grandvaux, and D. Lamarre Distinct antiviral signaling pathways in primary human hepatocytes and their differential disruption by HCV NS3 protease J Hepatol 52 2010 167 175
-
(2010)
J Hepatol
, vol.52
, pp. 167-175
-
-
Jouan, L.1
Melancon, P.2
Rodrigue-Gervais, I.G.3
Raymond, V.A.4
Selliah, S.5
Boucher, G.6
Bilodeau, M.7
Grandvaux, N.8
Lamarre, D.9
-
48
-
-
34249791501
-
Poly(I:C) and lipopolysaccharide innate sensing functions of circulating human myeloid dendritic cells are affected in vivo in hepatitis C virus-infected patients
-
I.G. Rodrigue-Gervais, L. Jouan, G. Beaule, D. Sauve, J. Bruneau, B. Willems, R.P. Sekaly, and D. Lamarre Poly(I:C) and lipopolysaccharide innate sensing functions of circulating human myeloid dendritic cells are affected in vivo in hepatitis C virus-infected patients J Virol 81 2007 5537 5546
-
(2007)
J Virol
, vol.81
, pp. 5537-5546
-
-
Rodrigue-Gervais, I.G.1
Jouan, L.2
Beaule, G.3
Sauve, D.4
Bruneau, J.5
Willems, B.6
Sekaly, R.P.7
Lamarre, D.8
-
49
-
-
79953890803
-
The structural biology of Toll-like receptors
-
I. Botos, D.M. Segal, and D.R. Davies The structural biology of Toll-like receptors Structure 19 2011 447 459
-
(2011)
Structure
, vol.19
, pp. 447-459
-
-
Botos, I.1
Segal, D.M.2
Davies, D.R.3
-
50
-
-
79959647082
-
RIG-I like receptors in antiviral immunity and therapeutic applications
-
R.C. Ireton, and M. Gale Jr. RIG-I like receptors in antiviral immunity and therapeutic applications Viruses 3 2011 906 919
-
(2011)
Viruses
, vol.3
, pp. 906-919
-
-
Ireton, R.C.1
Gale Jr., M.2
-
51
-
-
81555204380
-
Structural basis of RNA recognition and activation by innate immune receptor RIG-I
-
F. Jiang, A. Ramanathan, M.T. Miller, G.Q. Tang, M. Gale Jr., S.S. Patel, and J. Marcotrigiano Structural basis of RNA recognition and activation by innate immune receptor RIG-I Nature 479 2011 423 427
-
(2011)
Nature
, vol.479
, pp. 423-427
-
-
Jiang, F.1
Ramanathan, A.2
Miller, M.T.3
Tang, G.Q.4
Gale Jr., M.5
Patel, S.S.6
Marcotrigiano, J.7
-
52
-
-
80054685883
-
Structural insights into RNA recognition by RIG-I
-
D. Luo, S.C. Ding, A. Vela, A. Kohlway, B.D. Lindenbach, and A.M. Pyle Structural insights into RNA recognition by RIG-I Cell 147 2011 409 422
-
(2011)
Cell
, vol.147
, pp. 409-422
-
-
Luo, D.1
Ding, S.C.2
Vela, A.3
Kohlway, A.4
Lindenbach, B.D.5
Pyle, A.M.6
-
53
-
-
77953462221
-
Gold nanorod delivery of an ssRNA immune activator inhibits pandemic H1N1 influenza viral replication
-
K.V. Chakravarthy, A.C. Bonoiu, W.G. Davis, P. Ranjan, H. Ding, R. Hu, J.B. Bowzard, E.J. Bergey, J.M. Katz, and P.R. Knight Gold nanorod delivery of an ssRNA immune activator inhibits pandemic H1N1 influenza viral replication Proc Natl Acad Sci U S A 107 2010 10172 10177
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 10172-10177
-
-
Chakravarthy, K.V.1
Bonoiu, A.C.2
Davis, W.G.3
Ranjan, P.4
Ding, H.5
Hu, R.6
Bowzard, J.B.7
Bergey, E.J.8
Katz, J.M.9
Knight, P.R.10
-
54
-
-
78651410969
-
Coexpressed RIG-I agonist enhances humoral immune response to influenza virus DNA vaccine
-
J.M. Luke, G.G. Simon, J. Soderholm, J.S. Errett, J.T. August, M. Gale Jr., C.P. Hodgson, and J.A. Williams Coexpressed RIG-I agonist enhances humoral immune response to influenza virus DNA vaccine J Virol 85 2011 1370 1383
-
(2011)
J Virol
, vol.85
, pp. 1370-1383
-
-
Luke, J.M.1
Simon, G.G.2
Soderholm, J.3
Errett, J.S.4
August, J.T.5
Gale Jr., M.6
Hodgson, C.P.7
Williams, J.A.8
-
55
-
-
63149129764
-
A signaling polypeptide derived from an innate immune adaptor molecule can be harnessed as a new class of vaccine adjuvant
-
K. Kobiyama, F. Takeshita, K.J. Ishii, S. Koyama, T. Aoshi, S. Akira, A. Sakaue-Sawano, A. Miyawaki, Y. Yamanaka, and H. Hirano A signaling polypeptide derived from an innate immune adaptor molecule can be harnessed as a new class of vaccine adjuvant J Immunol 182 2009 1593 1601
-
(2009)
J Immunol
, vol.182
, pp. 1593-1601
-
-
Kobiyama, K.1
Takeshita, F.2
Ishii, K.J.3
Koyama, S.4
Aoshi, T.5
Akira, S.6
Sakaue-Sawano, A.7
Miyawaki, A.8
Yamanaka, Y.9
Hirano, H.10
-
56
-
-
44649110160
-
Viral and cellular microRNAs as determinants of viral pathogenesis and immunity
-
E. Gottwein, and B.R. Cullen Viral and cellular microRNAs as determinants of viral pathogenesis and immunity Cell Host Microbe 3 2008 375 387
-
(2008)
Cell Host Microbe
, vol.3
, pp. 375-387
-
-
Gottwein, E.1
Cullen, B.R.2
|