메뉴 건너뛰기




Volumn 1, Issue 2-3, 2008, Pages 83-86

The use of GEM models for experimental cancer therapeutics

Author keywords

[No Author keywords available]

Indexed keywords

CETUXIMAB; CISPLATIN; DOCETAXEL; DOXORUBICIN; ERLOTINIB;

EID: 64249114690     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.000570     Document Type: Editorial
Times cited : (41)

References (20)
  • 1
    • 4444254354 scopus 로고    scopus 로고
    • Antiangiogenic versus cytotoxic therapeutic approaches to human pancreas cancer: An experimental study with a vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor and gemcitabine
    • DOI 10.1016/j.ejphar.2004.07.062, PII S0014299904007952
    • Bocci, G., Danesi, R., Marangoni, G., Fioravanti, A., Boggi, U., Esposito, I., Fasciani, A., Boschi, E., Campani, D., Bevilacqua, G. et al. (2004). Antiangiogenic versus cytotoxic therapeutic approaches to human pancreas cancer: an experimental study with a vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor and gemcitabine. Eur. J. Pharmacol. 498, 9-18. (Pubitemid 39208055)
    • (2004) European Journal of Pharmacology , vol.498 , Issue.1-3 , pp. 9-18
    • Bocci, G.1    Danesi, R.2    Marangoni, G.3    Fioravanti, A.4    Boggi, U.5    Esposito, I.6    Fasciani, A.7    Boschi, E.8    Campani, D.9    Bevilacqua, G.10    Mosca, F.11    Del Tacca, M.12
  • 2
    • 0031469819 scopus 로고    scopus 로고
    • Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance
    • DOI 10.1038/37126
    • Boehm, T., Folkman, J., Browder, T. and O'Reilly, M. S. (1997). Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance. Nature 390, 404-407. (Pubitemid 28027321)
    • (1997) Nature , vol.390 , Issue.6658 , pp. 404-407
    • Boehm, T.1    Folkman, J.2    Browder, T.3    O'Reilly, M.S.4
  • 3
    • 30144443269 scopus 로고    scopus 로고
    • Paradoxical roles of the immune system during cancer development
    • DOI 10.1038/nrc1782
    • de Visser, K. E., Eichten, A. and Coussens, L. M. (2006). Paradoxical roles of the immune system during cancer development. Nat. Rev. Cancer 6, 24-37. (Pubitemid 43053650)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.1 , pp. 24-37
    • De Visser, K.E.1    Eichten, A.2    Coussens, L.M.3
  • 6
    • 34548217651 scopus 로고    scopus 로고
    • Maximizing mouse cancer models
    • Frese, K. K. and Tuveson, D. A. (2007). Maximizing mouse cancer models. Nat. Rev. Cancer 7, 645-658.
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 645-658
    • Frese, K.K.1    Tuveson, D.A.2
  • 8
    • 19344362405 scopus 로고    scopus 로고
    • G12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice
    • DOI 10.1016/j.ccr.2005.04.023, PII S1535610805001285
    • Hingorani, S. R., Wang, L., Multani, A. S., Combs, C., Deramaudt, T. B., Hruban, R. H., Rustgi, A. K., Chang, S. and Tuveson, D. A. (2005). Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice. Cancer Cell 7, 469-483. (Pubitemid 40719130)
    • (2005) Cancer Cell , vol.7 , Issue.5 , pp. 469-483
    • Hingorani, S.R.1    Wang, L.2    Multani, A.S.3    Combs, C.4    Deramaudt, T.B.5    Hruban, R.H.6    Rustgi, A.K.7    Chang, S.8    Tuveson, D.A.9
  • 10
    • 12344312012 scopus 로고    scopus 로고
    • Antiangiogenic therapy for human pancreatic carcinoma xenografts in nude mice
    • Jia, L., Zhang, M. H., Yuan, S. Z. and Huang, W. G. (2005). Antiangiogenic therapy for human pancreatic carcinoma xenografts in nude mice. World J. Gastroenterol. 11, 447-450. (Pubitemid 40125262)
    • (2005) World Journal of Gastroenterology , vol.11 , Issue.3 , pp. 447-450
    • Jia, L.1    Zhang, M.-H.2    Yuan, S.-Z.3    Huang, W.-G.4
  • 11
    • 35548941394 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled, randomized phase III trial of gemcitabine (G) plus bevacizumab (B) versus gemcitabine plus placebo (P) in patients (pts) with advanced pancreatic cancer (PC): A preliminary analysis of Cancer and Leukemia Group B (CALGB) 80303
    • 25, June 2007 Supplement
    • Kindler, H. L., Niedzwiecki, D., Hollis, D., Oraefo, E., Schrag, D., Hurwitz, H., McLeod, H. L., Mulcahy, M. F., Schilsky, R. L., Goldberg, R. M. et al. (2007). A double-blind, placebo-controlled, randomized phase III trial of gemcitabine (G) plus bevacizumab (B) versus gemcitabine plus placebo (P) in patients (pts) with advanced pancreatic cancer (PC): a preliminary analysis of Cancer and Leukemia Group B (CALGB) 80303. J. Clin. Oncol. 25, June 2007 Supplement.
    • (2007) J. Clin. Oncol.
    • Kindler, H.L.1    Niedzwiecki, D.2    Hollis, D.3    Oraefo, E.4    Schrag, D.5    Hurwitz, H.6    McLeod, H.L.7    Mulcahy, M.F.8    Schilsky, R.L.9    Goldberg, R.M.10
  • 12
    • 0036730017 scopus 로고    scopus 로고
    • A phase II study of troglitazone, an activator of the PPARgamma receptor, in patients with chemotherapyresistant metastatic colorectal cancer
    • Kulke, M. H., Demetri, G. D., Sharpless, N. E., Ryan, D. P., Shivdasani, R., Clark, J. S., Spiegelman, B. M., Kim, H., Mayer, R. J. and Fuchs, C. S. (2002). A phase II study of troglitazone, an activator of the PPARgamma receptor, in patients with chemotherapyresistant metastatic colorectal cancer. Cancer J. 8, 395-399.
    • (2002) Cancer J. , vol.8 , pp. 395-399
    • Kulke, M.H.1    Demetri, G.D.2    Sharpless, N.E.3    Ryan, D.P.4    Shivdasani, R.5    Clark, J.S.6    Spiegelman, B.M.7    Kim, H.8    Mayer, R.J.9    Fuchs, C.S.10
  • 13
    • 33744814638 scopus 로고    scopus 로고
    • Lung adenocarcinomas induced in mice by mutant EGF receptors found in human lung cancers respond to a tyrosine kinase inhibitor or to down-regulation of the receptors
    • DOI 10.1101/gad.1417406
    • Politi, K., Zakowski, M. F., Fan, P. D., Schonfeld, E. A., Pao, W. and Varmus, H. E. (2006). Lung adenocarcinomas induced in mice by mutant EGF receptors found in human lung cancers respond to a tyrosine kinase inhibitor or to down-regulation of the receptors. Genes Dev. 20, 1496-1510. (Pubitemid 43830656)
    • (2006) Genes and Development , vol.20 , Issue.11 , pp. 1496-1510
    • Politi, K.1    Zakowski, M.F.2    Fan, P.-D.3    Schonfeld, E.A.4    Pao, W.5    Varmus, H.E.6
  • 14
    • 42749092016 scopus 로고    scopus 로고
    • Modeling therapy resistance in genetically engineered mouse cancer models
    • Rottenberg, S. and Jonkers, J. (2007). Modeling therapy resistance in genetically engineered mouse cancer models. Drug Resist. Updat. 11, 51-60.
    • (2007) Drug Resist. Updat. , vol.11 , pp. 51-60
    • Rottenberg, S.1    Jonkers, J.2
  • 18
    • 48649110453 scopus 로고    scopus 로고
    • Direct orthotopic transplantation of fresh surgical specimen preserves CD133+ tumor cells in clinically relevant mouse models of Medulloblastoma and Glioma
    • Shu, Q., Wong, K. K., Su, J. M., Adesina, A. M., Yu, L. T., Tsang, Y. T., Antalffy, B. C., Baxter, P., Perlaky, L., Yang, J. et al. (2008). Direct orthotopic transplantation of fresh surgical specimen preserves CD133+ tumor cells in clinically relevant mouse models of Medulloblastoma and Glioma. Stem Cells 26, 1414-1424.
    • (2008) Stem Cells , vol.26 , pp. 1414-1424
    • Shu, Q.1    Wong, K.K.2    Su, J.M.3    Adesina, A.M.4    Yu, L.T.5    Tsang, Y.T.6    Antalffy, B.C.7    Baxter, P.8    Perlaky, L.9    Yang, J.10
  • 19
    • 0037120985 scopus 로고    scopus 로고
    • First clinical trials of endostatin yield lukewarm results
    • Twombly, R. (2002). First clinical trials of endostatin yield lukewarm results. J. Natl. Cancer Inst. 94, 1520-1521.
    • (2002) J. Natl. Cancer Inst. , vol.94 , pp. 1520-1521
    • Twombly, R.1
  • 20
    • 17144398060 scopus 로고    scopus 로고
    • Dietary genistein reduces metastasis in a postsurgical orthotopic breast cancer model
    • Vantyghem, S. A., Wilson, S. M., Postenka, C. O., Al-Katib, W., Tuck, A. B. and Chambers, A. F. (2005). Dietary genistein reduces metastasis in a postsurgical orthotopic breast cancer model. Cancer Res. 65, 3396-3403. (Pubitemid 40524625)
    • (2005) Cancer Research , vol.65 , Issue.8 , pp. 3396-3403
    • Vantyghem, S.A.1    Wilson, S.M.2    Postenka, C.O.3    Al-Katib, W.4    Tuck, A.B.5    Chambers, A.F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.