Lycopodine from Lycopodium clavatum extract inhibits proliferation of HeLa cells through induction of apoptosis via caspase-3 activation

European Journal of Pharmacology

Volumn 626, Issue 2-3, 2010, Pages 115-122

  Mandal, Sushil Kumar ^a   Biswas, Raktim ^a   Bhattacharyya, Soumya Sundar ^a   Paul, Saili ^a   Dutta, Suman ^a   Pathak, Surajit ^a   Khuda Bukhsh, Anisur Rahman ^a  

^a UNIVERSITY OF KALYANI   (India)

Author keywords

Anti cancer property; Apoptosis; Cell cycle; HeLa cell; Lycopodine; Lycopodium clavatum

Indexed keywords

4 DIMETHYLAMINOAZOBENZENE; ACETIC ACID ETHYL ESTER; ANTINEOPLASTIC AGENT; CASPASE 3; CYTOCHROME C; LYCOPODINE; NATURAL PRODUCT; PETROLEUM ETHER; PHENOBARBITAL; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ALTERNATIVE MEDICINE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CANCER INHIBITION; CELL GROWTH; CELL POPULATION; CELL PROLIFERATION; CELL STRUCTURE; CELL VIABILITY; CHROMATIN CONDENSATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVATION; FLUORESCENCE ACTIVATED CELL SORTING; GROWTH INHIBITION; HELA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; LIVER CARCINOGENESIS; LYCOPODIUM; MEMBRANE DEPOLARIZATION; MICROSCOPY; MITOCHONDRIAL MEMBRANE POTENTIAL; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTEIN SECRETION; UTERINE CERVIX CARCINOMA; WESTERN BLOTTING;

ACETATES; ALKALOIDS; ALKANES; APOPTOSIS; CASPASE 3; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HELA CELLS; HUMANS; LYCOPODIUM; MEMBRANE POTENTIAL, MITOCHONDRIAL; MOLECULAR WEIGHT; PLANT EXTRACTS; QUINOLIZINES; REACTIVE OXYGEN SPECIES;

EID: 70649092075     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2009.09.033     Document Type: Article

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