Oxidative stress in sickle cell disease: An overview of erythrocyte redox metabolism and current antioxidant therapeutic strategies

Free Radical Biology and Medicine

Volumn 65, Issue , 2013, Pages 1101-1109

  Silva, Danilo Grunig Humberto ^a   Belini Junior, Edis ^a   De Almeida, Eduardo Alves ^a   Bonini Domingos, Claudia Regina ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

Erythrocytes; Free radicals; Hemoglobin S; Redox process

Indexed keywords

ACETYLCYSTEINE; ALPHA TOCOPHEROL; ANTIOXIDANT; ARGININE; ASCORBIC ACID; GARLIC EXTRACT; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUTAMINE; GLUTATHIONE; HEMOGLOBIN S; HYDROXYUREA; IRON CHELATING AGENT; LEVACECARNINE; MEVINOLIN; REACTIVE OXYGEN METABOLITE; SIMVASTATIN; TETRAHYDROBIOPTERIN; THIOCTIC ACID; ZINC;

APOPTOSIS; BIOAVAILABILITY; CELL ADHESION; CELL METABOLISM; DEPOLYMERIZATION; DISEASE SEVERITY; ERYTHROCYTE; ERYTHROCYTE COUNT; HEMOGLOBIN SYNTHESIS; HEMOLYSIS; HUMAN; LIPID PEROXIDATION; NONHUMAN; OCCLUSION; OSMOTIC STRESS; OXIDATION REDUCTION POTENTIAL; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; POLYMERIZATION; PRIORITY JOURNAL; REPERFUSION INJURY; REVIEW; SICKLE CELL; SICKLE CELL ANEMIA; THALASSEMIA; VITAMIN SUPPLEMENTATION;

ERYTHROCYTES; FREE RADICALS; HEMOGLOBIN S; REDOX PROCESS;

ANEMIA, SICKLE CELL; ANTIOXIDANTS; BETA-GLOBINS; CELL ADHESION; ERYTHROCYTES; HEMOGLOBIN, SICKLE; HEMOLYSIS; HUMANS; OXIDATION-REDUCTION; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; REPERFUSION INJURY;

EID: 84884681035     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.08.181     Document Type: Review

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