Inhibition of suicidal erythrocyte death by blebbistatin

American Journal of Physiology - Cell Physiology

Volumn 301, Issue 2, 2011, Pages

  Lang, Elisabeth ^a   Qadri, Syed M ^a   Zelenak, Christine ^a   Gu, Shuchen ^a   Rotte, Anand ^a   Draeger, Annette ^b   Lang, Florian ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY OF BERN   (Switzerland)

Author keywords

Calcium; Cell volume; Eryptosis; Phosphatidylserine; Scrambling

Indexed keywords

BLEBBISTATIN; CALCIUM; GLUCOSE; LIPOCORTIN 5; PHOSPHATIDYLSERINE; REACTIVE OXYGEN METABOLITE;

ARTICLE; BINDING KINETICS; CALCIUM CELL LEVEL; CELL DEATH; CELL ENERGY; CELL MEMBRANE; CELL SURFACE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOSOL; ERYPTOSIS; ERYTHROCYTE; ERYTHROCYTE VOLUME; FLUORESCENCE ACTIVATED CELL SORTING; HEMATOCRIT; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IN VITRO STUDY; INHIBITION KINETICS; OSMOTIC STRESS; PRIORITY JOURNAL;

ANALYSIS OF VARIANCE; ANNEXIN A5; BLOOD GLUCOSE; CALCIUM; CELL DEATH; CELL SEPARATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENERGY METABOLISM; ERYTHROCYTE MEMBRANE; ERYTHROCYTES; FLOW CYTOMETRY; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; HUMANS; MICROSCOPY, CONFOCAL; OSMOTIC PRESSURE; PHOSPHATIDYLSERINES;

EID: 79961005303     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00043.2011     Document Type: Article

References (67)

1. Allingham JS, Smith R, Rayment I. The structural basis of blebbistatin inhibition and specificity for myosin II. Nat Struct Mol Biol 12: 378-379, 2005.
2. Andrews DA, Low PS. Role of red blood cells in thrombosis. Curr Opin Hematol 6: 76-82, 1999.
3. Avissar N, de Vries A, Ben Shaul Y, Cohen I. Actin-activated ATPase from human erythrocytes. Biochim Biophys Acta 375: 35-43, 1975.
4. Basu S, Banerjee D, Ghosh M, Chakrabarti A. Erythrocyte membrane defects and asymmetry in paroxysmal nocturnal hemoglobinuria and myelodysplastic syndrome. Hematology 15: 236-239, 2010.
5. Berg CP, Engels IH, Rothbart A, Lauber K, Renz A, Schlosser SF, Schulze-Osthoff K, Wesselborg S. Human mature red blood cells express caspase-3 and caspase-8, but are devoid of mitochondrial regulators of apoptosis. Cell Death Differ 8: 1197-1206, 2001.
6. Bernhardt I, Weiss E, Robinson HC, Wilkins R, Bennekou P. Differential effect of HOE642 on two separate monovalent cation transporters in the human red cell membrane. Cell Physiol Biochem 20: 601-606, 2007.
7. Bhavsar SK, Bobbala D, Xuan NT, Foller M, Lang F. Stimulation of suicidal erythrocyte death by alpha-lipoic acid. Cell Physiol Biochem 26: 859-868, 2010.
8. Bhavsar SK, Eberhard M, Bobbala D, Lang F. Monensin induced suicidal erythrocyte death. Cell Physiol Biochem 25: 745-752, 2010.
9. Bobbala D, Alesutan I, Foller M, Huber SM, Lang F. Effect of anandamide in plasmodium Berghei-infected mice. Cell Physiol Biochem 26: 355-362, 2010.
10. Bookchin RM, Ortiz OE, Lew VL. Activation of calcium-dependent potassium channels in deoxygenated sickled red cells. Prog Clin Biol Res 240: 193-200, 1987.
11. Bratosin D, Estaquier J, Petit F, Arnoult D, Quatannens B, Tissier JP, Slomianny C, Sartiaux C, Alonso C, Huart JJ, Montreuil J, Ameisen JC. Programmed cell death in mature erythrocytes: a model for investigating death effector pathways operating in the absence of mitochondria. Cell Death Differ 8: 1143-1156, 2001.
12. Braun M, Foller M, Gulbins E, Lang F. Eryptosis triggered by bismuth. Biometals 22: 453-460, 2009.
13. Brugnara C, de Franceschi L, Alper SL. Inhibition of Ca(2+)-dependent K+ transport and cell dehydration in sickle erythrocytes by clotrimazole and other imidazole derivatives. J Clin Invest 92: 520-526, 1993.
14. Chadebech P, Habibi A, Nzouakou R, Bachir D, Meunier-Costes N, Bonin P, Rodet M, Chami B, Galacteros F, Bierling P, Noizat-Pirenne F. Delayed hemolytic transfusion reaction in sickle cell disease patients: evidence of an emerging syndrome with suicidal red blood cell death. Transfusion 49: 1785-1792, 2009.
15. Chadebech P, Michel M, Janvier D, Yamada K, Copie-Bergman C, Bodivit G, Bensussan A, Fournie JJ, Godeau B, Bierling P, Izui S, Noizat-Pirenne F. IgA-mediated human autoimmune hemolytic anemia as a result of hemagglutination in the spleen, but independent of complement activation and FcalphaRI. Blood 116: 4141-4147, 2010.
16. Chung SM, Bae ON, Lim KM, Noh JY, Lee MY, Jung YS, Chung JH. Lysophosphatidic acid induces thrombogenic activity through phosphatidylserine exposure and procoagulant microvesicle generation in human erythrocytes. Arterioscler Thromb Vasc Biol 27: 414-421, 2007.
17. - cotransporter? Am J Physiol Cell Physiol 289: C68-C81, 2005.
18. Cibert C, Pruliere G, Lacombe C, Deprette C, Cassoly R. Calculation of a Gap restoration in the membrane skeleton of the red blood cell: possible role for myosin II in local repair. Biophys J 76: 1153-1165, 1999.
19. Closse C, Dachary-Prigent J, Boisseau MR. Phosphatidylserine-related adhesion of human erythrocytes to vascular endothelium. Br J Haematol 107: 300-302, 1999.
20. Delic D, Warskulat U, Borsch E, Al Qahtani S, Al Quraishi S, Haussinger D, Wunderlich F. Loss of ability to self-heal malaria upon taurine transporter deletion. Infect Immun 78: 1642-1649, 2010.
21. Dou Y, Arlock P, Arner A. Blebbistatin specifically inhibits actin-myosin interaction in mouse cardiac muscle. Am J Physiol Cell Physiol 293: C1148-C1153, 2007.
22. Eberhard M, Ferlinz K, Alizzi K, Cacciato PM, Faggio C, Foller M, Lang F. FTY720-induced suicidal erythrocyte death. Cell Physiol Biochem 26: 761-766, 2010.
23. Foller M, Bobbala D, Koka S, Huber SM, Gulbins E, Lang F. Suicide for survival- death of infected erythrocytes as a host mechanism to survive malaria. Cell Physiol Biochem 24: 133-140, 2009.
24. Foller M, Kasinathan RS, Koka S, Lang C, Shumilina E, Birnbaumer L, Lang F, Huber SM. TRPC6 contributes to the Ca(2+) leak of human erythrocytes. Cell Physiol Biochem 21: 183-192, 2008.
25. Foller M, Sopjani M, Koka S, Gu S, Mahmud H, Wang K, Floride E, Schleicher E, Schulz E, Munzel T, Lang F. Regulation of erythrocyte survival by AMP-activated protein kinase. FASEB J 23: 1072-1080, 2009.
26. Fowler VM. An actomyosin contractile mechanism for erythrocyte shape transformations. J Cell Biochem 31: 1-9, 1986.
27. Gallagher PG, Chang SH, Rettig MP, Neely JE, Hillery CA, Smith BD, Low PS. Altered erythrocyte endothelial adherence and membrane phospholipid asymmetry in hereditary hydrocytosis. Blood 101: 4625-4627, 2003.
28. Goeckeler ZM, Bridgman PC, Wysolmerski RB. Nonmuscle myosin II is responsible for maintaining endothelial cell basal tone and stress fiber integrity. Am J Physiol Cell Physiol 295: C994-C1006, 2008.
29. Gu BJ, Rathsam C, Stokes L, McGeachie AB, Wiley JS. Extracellular ATP dissociates nonmuscle myosin from P2X(7) complex: this dissociation regulates P2X(7) pore formation. Am J Physiol Cell Physiol 297: C430-C439, 2009.
30. Kaestner L, Bernhardt I. Ion channels in the human red blood cell membrane: their further investigation and physiological relevance. Bioelectrochemistry 55: 71-74, 2002.
31. Kaestner L, Christophersen P, Bernhardt I, Bennekou P. The nonselective voltage-activated cation channel in the human red blood cell membrane: reconciliation between two conflicting reports and further characterisation. Bioelectrochemistry 52: 117-125, 2000.
32. Keerthivasan G, Small S, Liu H, Wickrema A, Crispino JD. Vesicle trafficking plays a novel role in erythroblast enucleation. Blood 116: 3331-3340, 2010.
33. Klarl BA, Lang PA, Kempe DS, Niemoeller OM, Akel A, Sobiesiak M, Eisele K, Podolski M, Huber SM, Wieder T, Lang F. Protein kinase C mediates erythrocyte "programmed cell death" following glucose depletion. Am J Physiol Cell Physiol 290: C244-C253, 2006.
34. Koka S, Bobbala D, Lang C, Boini KM, Huber SM, Lang F. Influence of paclitaxel on parasitemia and survival of Plasmodium berghei infected mice. Cell Physiol Biochem 23: 191-198, 2009.
35. Krejbich-Trotot P, Denizot M, Hoarau JJ, Jaffar-Bandjee MC, Das T, Gasque P. Chikungunya virus mobilizes the apoptotic machinery to invade host cell defenses. FASEB J 25: 314-325, 2011.
36. Lang F, Gulbins E, Lang PA, Zappulla D, Foller M. Ceramide in suicidal death of erythrocytes. Cell Physiol Biochem 26: 21-28, 2010.
37. Lang F, Gulbins E, Lerche H, Huber SM, Kempe DS, Föller M. Eryptosis, a window to systemic disease. Cell Physiol Biochem 22: 373-380, 2008.
38. Lang PA, Kasinathan RS, Brand VB, Duranton C, Lang C, Koka S, Shumilina E, Kempe DS, Tanneur V, Akel A, Lang KS, Foller M, Kun JF, Kremsner PG, Wesselborg S, Laufer S, Clemen CS, Herr C, Noegel AA, Wieder T, Gulbins E, Lang F, Huber SM. Accelerated clearance of Plasmodium-infected erythrocytes in sickle cell trait and annexin-A7 deficiency. Cell Physiol Biochem 24: 415-428, 2009.
39. Mahmud H, Foller M, Lang F. Arsenic-induced suicidal erythrocyte death. Arch Toxicol 83: 107-113, 2009.
40. Mahmud H, Mauro D, Foller M, Lang F. Inhibitory effect of thymol on suicidal erythrocyte death. Cell Physiol Biochem 24: 407-414, 2009.
41. Mahmud H, Mauro D, Qadri SM, Foller M, Lang F. Triggering of suicidal erythrocyte death by amphotericin B. Cell Physiol Biochem 24: 263-270, 2009.
42. Malek AM, Xu C, Kim ES, Alper SL. Hypertonicity triggers RhoAdependent assembly of myosin-containing striated polygonal actin networks in endothelial cells. Am J Physiol Cell Physiol 292: C1645-C1659, 2007.
43. Mandal D, Moitra PK, Saha S, Basu J. Caspase 3 regulates phosphatidylserine externalization and phagocytosis of oxidatively stressed erythrocytes. FEBS Lett 513: 184-188, 2002.
44. Marqueze-Pouey B, Martin-Moutot N, Sakkou-Norton M, Leveque C, Ji Y, Cornet V, Hsiao WL, Seagar M. Toxicity and endocytosis of spinocerebellar ataxia type 6 polyglutamine domains: role of myosin IIb. Traffic 9: 1088-1100, 2008.
45. 2+ concentration on force produced during stretch of skeletal muscle fibers. Am J Physiol Cell Physiol 299: C1127-C1135, 2010.
46. Moss DK, Wilde A, Lane JD. Dynamic release of nuclear RanGTP triggers TPX2-dependent microtubule assembly during the apoptotic execution phase. J Cell Sci 122: 644-655, 2009.
47. O'Hara SP, Gajdos GB, Trussoni CE, Splinter PL, LaRusso NF. Cholangiocyte myosin IIB is required for localized aggregation of sodium glucose cotransporter 1 to sites of Cryptosporidium parvum cellular invasion and facilitates parasite internalization. Infect Immun 78: 2927-2936, 2010.
48. Ohgushi M, Matsumura M, Eiraku M, Murakami K, Aramaki T, Nishiyama A, Muguruma K, Nakano T, Suga H, Ueno M, Ishizaki T, Suemori H, Narumiya S, Niwa H, Sasai Y. Molecular pathway and cell state responsible for dissociation-induced apoptosis in human pluripotent stem cells. Cell Stem Cell 7: 225-239, 2010.
49. Orlando KA, Stone NL, Pittman RN. Rho kinase regulates fragmentation and phagocytosis of apoptotic cells. Exp Cell Res 312: 5-15, 2006.
50. Pandolfi A, Di Pietro N, Sirolli V, Giardinelli A, Di Silvestre S, Amoroso L, Di Tomo P, Capani F, Consoli A, Bonomini M. Mechanisms of uremic erythrocyte-induced adhesion of human monocytes to cultured endothelial cells. J Cell Physiol 213: 699-709, 2007.
51. Papakonstanti EA, Stournaras C. Cell responses regulated by early reorganization of actin cytoskeleton. FEBS Lett 582: 2120-2127, 2008.
52. Ponsaerts R, D'hondt C, Bultynck G, Srinivas SP, Vereecke J, Himpens B. The myosin II ATPase inhibitor blebbistatin prevents thrombininduced inhibition of intercellular calcium wave propagation in corneal endothelial cells. Invest Ophthalmol Vis Sci 49: 4816-4827, 2008.
53. Ponsaerts R, De Vuyst E, Retamal M, D'hondt C, Vermeire D, Wang N, De Smedt H, Zimmermann P, Himpens B, Vereecke J, Leybaert L, Bultynck G. Intramolecular loop/tail interactions are essential for connexin 43-hemichannel activity. FASEB J 24: 4378-4395, 2010.
54. Rao J, Li N. Microfilament actin remodeling as a potential target for cancer drug development. Curr Cancer Drug Targets 4: 345-354, 2004.
55. Sagan D, Jermnim N, Tangvarasittichai O. CD95 is not functional in human erythrocytes. Int J Lab Hematol 32: e244-e247, 2010.
56. Sbrana F, Sassoli C, Meacci E, Nosi D, Squecco R, Paternostro F, Tiribilli B, Zecchi-Orlandini S, Francini F, Formigli L. Role for stress fiber contraction in surface tension development and stretch-activated channel regulation in C2C12 myoblasts. Am J Physiol Cell Physiol 295: C160-C172, 2008.
57. Siraskar B, Ballal A, Bobbala D, Foller M, Lang F. Effect of amphotericin B on parasitemia and survival of plasmodium berghei-infected mice. Cell Physiol Biochem 26: 347-354, 2010.
58. Svetina S, Bozic B, Derganc J, Zeks B. Mechanical and functional aspects of membrane skeletons. Cell Mol Biol Lett 6: 677-690, 2001.
59. Vasudevan S, Chen GC, Andika M, Agarwal S, Chen P, Olivo M. Dynamic quantitative photothermal monitoring of cell death of individual human red blood cells upon glucose depletion. J Biomed Opt 15: 057001, 2010.
60. Waheed F, Speight P, Kawai G, Dan Q, Kapus A, Szaszi K. Extracellular signal-regulated kinase and GEF-H1 mediate depolarization-induced Rho activation and paracellular permeability increase. Am J Physiol Cell Physiol 298: C1376-C1387, 2010.
61. Watanabe M, Yumoto M, Tanaka H, Wang HH, Katayama T, Yoshiyama S, Black J, Thatcher SE, Kohama K. Blebbistatin, a myosin II inhibitor, suppresses contraction and disrupts contractile filaments organization of skinned taenia cecum from guinea pig. Am J Physiol Cell Physiol 298: C1118-C1126, 2010.
62. Weil M, Jacobson MD, Raff MC. Are caspases involved in the death of cells with a transcriptionally inactive nucleus? Sperm and chicken erythrocytes. J Cell Sci 111: 2707-2715, 1998.
63. Wood BL, Gibson DF, Tait JF. Increased erythrocyte phosphatidylserine exposure in sickle cell disease: flow-cytometric measurement and clinical associations. Blood 88: 1873-1880, 1996.
64. Wyss HM, Henderson JM, Byfield FJ, Bruggeman LA, Ding Y, Huang C, Suh JH, Franke T, Mele E, Pollak MR, Miner JH, Janmey PA, Weitz DA, Miller RT. Biophysical properties of normal and diseased renal glomeruli. Am J Physiol Cell Physiol 300: C397-C405, 2011.
65. Xiao L, Eto M, Kazanietz MG. ROCK mediates phorbol ester-induced apoptosis in prostate cancer cells via p21Cip1 up-regulation and JNK. J Biol Chem 284: 29365-29375, 2009.
66. Zappulla D. Environmental stress, erythrocyte dysfunctions, inflammation, and the metabolic syndrome: adaptations to CO2 increases? J Cardiometab Syndr 3: 30-34, 2008.
67. Zwaal RF, Comfurius P, Bevers EM. Surface exposure of phosphatidylserine in pathological cells. Cell Mol Life Sci 62: 971-988, 2005.